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List of works by Shimon Sakaguchi

4-1BB-dependent inhibition of immunosuppression by activated CD4+CD25+ T cells

scientific article published on 23 December 2003

A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model

scientific article published on August 2007

A distinct subpopulation of CD25- T-follicular regulatory cells localizes in the germinal centers

scientific article published on 11 July 2017

A novel model of rheumatoid arthritis-associated interstitial lung disease in SKG mice

scientific article published on 20 December 2011

A novel modifier of regulatory T cells

scientific article published in July 2009

A paragon of self-tolerance: CD25+CD4+ regulatory T cells and the control of immune responses

scientific article

A promoter-level mammalian expression atlas

scientific article

A role for Dicer in immune regulation

scientific article

A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

scientific article

A simple detection method for low-affinity membrane protein interactions by baculoviral display

scientific article

A trans-ethnic genetic study of rheumatoid arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations ⬇️

scientific article published on May 24, 2011

Addendum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment.

scientific article published in October 2017

Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity

scientific article

Alteration of the immune environment in bone marrow from children with recurrent B cell precursor acute lymphoblastic leukemia

scientific article

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

scientific article published in Nature

Analyses of Peripheral Blood Mononuclear Cells in Operational Tolerance After Pediatric Living Donor Liver Transplantation

scientific article published on 01 December 2004

Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation

scientific article published in July 2005

Animal models of arthritis caused by systemic alteration of the immune system

scientific article

Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans.

scientific article published on 14 October 2013

Antibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes

scientific article

Are naïve T cells and class-switched memory (IgD CD27) B cells not essential for establishment and maintenance of pregnancy? Insights from a case of common variable immunodeficiency with pregnancy

scientific article published on 08 September 2018

Arthritis and pneumonitis produced by the same T cell clones from mice with spontaneous autoimmune arthritis

scientific article published on 18 August 2008

Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.

scientific article

Autoimmune arthritis caused by altered thymic T-cell selection due to a mutation of the ZAP-70 gene.

scientific article

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations

scientific article

CD25+CD4+ T cells in human cord blood: an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene.

scientific article

CD25+CD4+ regulatory T cells in infection

scientific article published on 01 June 2009

CD28 signals the differential control of regulatory T cells and effector T cells

scientific article published on 01 April 2014

CD4+ Tregs and immune control

scientific article

CD4+ regulatory cells as a potential immunotherapy

scientific article

CD4+CD25+Foxp3+ T cells and CD4+CD25-Foxp3+ T cells in aged mice

scientific article published on June 2006

CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2

scientific article

CD8 T cell-intrinsic GITR is required for T cell clonal expansion and mouse survival following severe influenza infection

scientific article published on 12 November 2010

CD8⁺ tumor-infiltrating lymphocytes at primary sites as a possible prognostic factor of cutaneous angiosarcoma.

scientific article

CSF-1-dependent red pulp macrophages regulate CD4 T cell responses

scientific article published on 14 January 2011

Cancer/testis antigens are novel targets of immunotherapy for adult T-cell leukemia/lymphoma

scientific article published on 8 February 2012

Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation

scientific article published on 30 June 2011

Chronic arthritis leads to disturbances in the bone collagen network.

scientific article

Clinical importance of the expression of CD4+CD8+ T cells in Renal Cell Carcinoma

scientific article published on 17 January 2020

Clinical, immunological, and pathological aspects of operational tolerance after pediatric living-donor liver transplantation

scientific article

Combination of IL-2, rapamycin, DNA methyltransferase and histone deacetylase inhibitors for the expansion of human regulatory T cells

scientific article published on 28 July 2016

Comment on "cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans"

scientific article published on 01 April 2015

Complement drives Th17 cell differentiation and triggers autoimmune arthritis.

scientific article published on 10 May 2010

Comprehensive exploration of autoantibody in Behçet's disease: a novel autoantibody to claudin-1, an essential protein for tight junctions, is identified

scientific article published on 29 April 2014

Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

scientific article

Conditional stability of T cells

scientific article published in Nature

Constitutive expression of IDO by dendritic cells of mesenteric lymph nodes: functional involvement of the CTLA-4/B7 and CCL22/CCR4 interactions.

scientific article published in November 2009

Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression

scientific article published on 20 May 2013

Continuous T cell receptor signals maintain a functional regulatory T cell pool.

scientific article published on 6 November 2014

Contribution of Th-1, Th-2, Th-17 or regulatory T cells to connective tissue diseases

scientific article

Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells

scientific article published in November 2004

Control of Germinal Center Responses by T-Follicular Regulatory Cells

article

Control of Regulatory T Cells by Co-signal Molecules

scientific article published on 01 January 2019

Control of autoimmune myocarditis and multiorgan inflammation by glucocorticoid-induced TNF receptor family-related protein(high), Foxp3-expressing CD25+ and CD25- regulatory T cells

scientific article published on 01 April 2006

Control of autoimmunity by naturally arising regulatory CD4+ T cells

scientific article published on January 2003

Control of foreign Ag-specific Ab responses by Treg and Tfr

scientific article published on 20 June 2020

Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor.

scientific article

Control of immune responses by naturally arising CD4+ regulatory T cells that express toll-like receptors

scientific article published on February 2003

Control of regulatory T cell development by the transcription factor Foxp3

scientific article (publication date: 14 February 2003)

Conversion of alloantigen-specific CD8+ T cell anergy to CD8+ T cell priming through in vivo ligation of glucocorticoid-induced TNF receptor

scientific article published on 01 May 2006

Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19

scientific article published on 01 October 2019

Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells

scientific article published on June 2004

Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

scientific article

Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

scientific article

Definition of target antigens for naturally occurring CD4(+) CD25(+) regulatory T cells

scientific article

Delineation of immunoregulatory properties of adult T-cell leukemia cells

scientific article published on July 2006

Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease

scientific article

Detection of self-reactive CD8⁺ T cells with an anergic phenotype in healthy individuals

scientific article published in Science

Development and Maintenance of Regulatory T cells ⬇️

scientific article published on March 21, 2013

Development and function of CD25+CD4+ regulatory T cells

scientific article published on April 2004

Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice

scientific article published on 01 February 2005

Dietary Folic Acid Promotes Survival of Foxp3+ Regulatory T Cells in the Colon ⬇️

scientific article published on 06 August 2012

Differential control of allo-antigen-specific regulatory T cells and effector T cells by anti-CD4 and other agents in establishing transplantation tolerance.

scientific article published on 19 February 2009

Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody

scientific article published on 26 December 2018

Differential effects of inhibition of bone morphogenic protein (BMP) signalling on T-cell activation and differentiation

scientific article published on 20 December 2011

Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation

scientific article published on 27 March 2014

Distinct contribution of IL-6, TNF-alpha, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice

scientific article published on August 2004

Dynamic Imprinting of the Treg Cell-Specific Epigenetic Signature in Developing Thymic Regulatory T Cells

scientific article published on 11 October 2019

Dynamics of effector and naïve Regulatory T cells throughout pregnancy

scientific article published on 19 April 2020

Dynamics of peripheral tolerance and immune regulation mediated by Treg

scientific article published in September 2009

Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine

scientific article published on 22 June 2016

Effector Regulatory T Cells Reflect the Equilibrium between Antitumor Immunity and Autoimmunity in Adult T-cell Leukemia.

scientific article published on 23 May 2016

Emerging challenges in regulatory T cell function and biology

scientific article published on 01 August 2007

Emerging possibilities in the development and function of regulatory T cells

scientific article

Enhancement of T-cell-mediated anti-tumour immunity via the ectopically expressed glucocorticoid-induced tumour necrosis factor receptor-related receptor ligand (GITRL) on tumours

scientific article published on 01 August 2009

Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction

scientific article published on 23 April 2019

Epigenetic control of thymic Treg-cell development

scientific article

Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation

scientific article published on 15 May 2020

Erratum

scholarly article published in Journal of Experimental Medicine

Erratum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment.

scientific article

Essential Roles of SATB1 in Specifying T Lymphocyte Subsets

scientific article published in May 2017

FANTOM5 CAGE profiles of human and mouse samples

scientific article published on 29 August 2017

FOXP3+ regulatory T cells in the human immune system

scientific article (publication date: 18 June 2010)

FOXP3+ regulatory T cells: control of FOXP3 expression by pharmacological agents ⬇️

scientific article published on January 13, 2011

FRT - Fondation Rene Touraine

Factors affecting operational tolerance after pediatric living-donor liver transplantation: impact of early post-transplant events and HLA match* ⬇️

scientific article published on November 26, 2011

Foxo1 and Foxo3 help Foxp3 ⬇️

scientific article published on December 14, 2010

Foxp3 and Aire in thymus-generated Treg cells: a link in self-tolerance

scientific article published on 01 April 2007

Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1

scientific article

Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease

scientific article

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

scholarly article

Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis.

scientific article

Foxp3: a critical regulator of the development and function of regulatory T cells

scientific article published on July 2004

Foxp3⁺ T(reg) cells in humoral immunity.

scientific article published on 09 December 2013

Functional Roles of the IgM Fc Receptor in the Immune System

scientific article published on 03 May 2019

Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor

scientific article published on 21 May 2009

Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection

scientific article published in March 2004

GITR activation induces an opposite effect on alloreactive CD4(+) and CD8(+) T cells in graft-versus-host disease

scientific article

Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis.

scientific article published in August 2009

Genetic and epigenetic basis of Treg cell development and function: from a FoxP3-centered view to an epigenome-defined view of natural Treg cells

scientific article published on May 2014

Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity.

scientific article published on June 2006

Glucocorticoid-induced tumour necrosis factor receptor family-related receptor signalling exacerbates hapten-induced colitis by CD4+ T cells

scientific article published on 01 December 2006

Graded attenuation of TCR signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function.

scientific article published on 19 July 2010

Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment.

scientific article published on 19 December 2016

Guidelines for the use of flow cytometry and cell sorting in immunological studies

scientific article published on October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

scientific article published on 01 October 2019

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

scholarly article

HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo

scientific article

HTLV-1 bZIP factor-mediated dysfunction of regulatory T cells in vivo.

scientific article published on 6 June 2011

Homeostasis of thymus-derived Foxp3+ regulatory T cells is controlled by ultraviolet B exposure in the skin

scientific article published on 27 October 2014

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

scientific article

Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer

scientific article published on 01 February 2019

Human FoxP3+ regulatory T cells in systemic autoimmune diseases

scientific article published on 18 May 2011

Human FoxP3+CD4+ regulatory T cells: their knowns and unknowns ⬇️

scientific article published on February 8, 2011

Hyper-Progressive Disease: The Potential Role and Consequences of T-Regulatory Cells Foiling Anti-PD-1 Cancer Immunotherapy

scientific article published on 26 December 2020

Hypomethylation of the Treg-Specific Demethylated Region in FOXP3 Is a Hallmark of the Regulatory T-cell Subtype in Adult T-cell Leukemia

scientific article published on 17 December 2015

ICER/CREM-mediated transcriptional attenuation of IL-2 and its role in suppression by regulatory T cells

article

ICOS+ Foxp3+ TILs in gastric cancer are prognostic markers and effector regulatory T cells associated with Helicobacter pylori

scientific article

IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells

scientific article published on 01 February 2004

Identification of Novel and Noninvasive Biomarkers of Acute Cellular Rejection After Liver Transplantation by Protein Microarray

scientific article

Identification of novel markers for mouse CD4(+) T follicular helper cells

scientific article published on 14 October 2013

Immune rejection of mouse tumors expressing mutated self.

scientific article published on 7 April 2009

Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system.

scientific article published on 13 April 2016

Immunologic tolerance maintained by regulatory T cells: implications for autoimmunity, tumor immunity and transplantation tolerance.

scientific article

Immunology. Damping by depletion

scientific article published in Science

Immunology. Early life Aire

scientific article published on 30 April 2015

Impaired T cell receptor signaling and development of T cell-mediated autoimmune arthritis

scientific article published on 16 January 2020

In vivo induction of T-follicular helper cells by modulation of regulatory T cell function

scientific article published on 01 January 2015

Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells

scientific article published in October 2009

Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells

scientific article published on 5 July 2004

Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood

scientific article published on 11 April 2016

Induction of tolerance by adoptive transfer of Treg cells

scientific article published on January 2007

Innate Myeloid Cell Subset-Specific Gene Expression Patterns in the Human Colon are Altered in Crohn's Disease Patients

article

Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation

scientific article published on 4 November 2014

Intracellular tumor-associated antigens represent effective targets for passive immunotherapy.

scientific article published on 8 February 2012

Investigation of the relationship between the onset of arthritis and uveitis in genetically predisposed SKG mice

scientific article

Lamtor1 Is Critically Required for CD4(+) T Cell Proliferation and Regulatory T Cell Suppressive Function.

scientific article

Long-term Functioning of Allogeneic Islets in Subcutaneous Tissue Pretreated with a Novel Cyclic Peptide without Immunosuppressive Medication

scientific article published on 30 August 2017

Loss of TET proteins in regulatory T cells promotes abnormal proliferation, Foxp3 destabilization and IL-17 expression

scientific article published on 01 April 2019

Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice ⬇️

scientific article published on 10 June 2016

MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cells

scientific article published on 9 July 2015

Maturation of effector regulatory T cells ⬇️

scientific article published on April 1, 2011

Minimal but essential doses of immunosuppression: a more realistic approach to improve long-term outcomes for pediatric living-donor liver transplantation

scientific article published on 01 April 2011

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

scientific article published in January 2017

Molecular Determinants of Regulatory T Cell Development: The Essential Roles of Epigenetic Changes ⬇️

scientific article published on May 10, 2013

Molecular control of regulatory T cell development and function

scientific article published on 21 October 2017

Multiple antitumor mechanisms downstream of prophylactic regulatory T-cell depletion

scientific article published on 23 March 2010

Multiple treg suppressive modules and their adaptability.

scientific article published on 29 June 2012

Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma

scientific article published in 2022

NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner

scientific article published in February 2004

Natural regulatory T cells: mechanisms of suppression

scientific article published on 24 January 2007

Naturally arising CD25+CD4+ regulatory T cells in maintaining immunologic self-tolerance and preventing autoimmune disease

scientific article published on December 2003

Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth

scientific article

New Treg cell-based therapies of autoimmune diseases: towards antigen-specific immune suppression

scientific article published on 18 August 2020

Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis

article

Novel interferon-γ enzyme-linked immunoSpot assay using activated cells for identifying hypersensitivity-inducing drug culprits

scientific article published on 14 March 2017

Overcoming regulatory T-cell suppression by a lyophilized preparation of Streptococcus pyogenes

scientific article published on 26 February 2013

PD-1 regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer

scientific article published on 26 April 2019

PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis

scientific article published on 15 October 2020

Peacekeepers of the immune system

scientific article published on 01 October 2006

Pillars Article: Control of Regulatory T Cell Development by the Transcription Factor Foxp3. Science 2003. 299: 1057-1061.

scientific article published in February 2017

Pillars article: immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 1995 ⬇️

scientific article published on April 1, 2011

Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.

scientific article

Pregnancy amelioration of arthritis in SKG mice corresponds with alterations in serum amyloid A3 levels

scientific article

Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by 18F-FDG-PET is associated with the KRAS mutation status and prognosis.

scientific article

Preparation of Immunotolerant Space under the Skin and Transplantation of Islets in the Pockets

scientific article published on 28 December 2018

Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function

scientific article published on 07 August 2020

Re-establishing immunological self-tolerance in autoimmune disease ⬇️

scientific article published on 06 January 2012

Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4.

scientific article published on 12 May 2017

Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity

scientific article published on 11 February 2019

Reduction of retrovirus-induced immunosuppression by in vivo modulation of T cells during acute infection

scientific article

Regulation of Zap70 expression during thymocyte development enables temporal separation of CD4 and CD8 repertoire selection at different signaling thresholds

scientific article published on 23 March 2010

Regulation of autoimmune diabetes by non-islet-specific T cells - a role for the glucocorticoid-induced TNF receptor

scientific article published on 01 February 2004

Regulation of tumour immunity by CD25+ T cells

scientific article

Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases

scientific article published on 26 April 2020

Regulatory T Cells and Human Disease

scientific article published on 04 February 2020

Regulatory T Cells: History and Perspective ⬇️

scientific article published on January 1, 2011

Regulatory T cell-mediated suppression: potential role of ICER.

scientific article published on 6 October 2006

Regulatory T cells

scientific article published on 01 August 2006

Regulatory T cells - a brief history and perspective

scientific article published on November 2007

Regulatory T cells and immune tolerance

scientific article (publication date: 30 May 2008)

Regulatory T cells as potential immunotherapy in allergy

scientific article published on December 2006

Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4.

scientific article published on 6 December 2014

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

scientific article

Regulatory T cells expressing PPAR-γ control inflammation in obesity

scientific article published on 01 July 2012

Regulatory T cells expressing abundant CTLA-4 on the cell surface with a proliferative gene profile are key features of human head and neck cancer

scientific article published on 16 December 2018

Regulatory T cells for the control of physiological and pathological immune responses

scientific article published on 23 November 2011

Regulatory T cells in cancer immunotherapy

scientific article published on 14 January 2014

Regulatory T cells in cancer immunotherapy

scientific article published on 20 December 2016

Regulatory T cells in immune surveillance and treatment of cancer.

scientific article

Regulatory T cells in immunologic self-tolerance and autoimmune disease

scientific article

Regulatory T cells in the past and for the future

scientific article

Regulatory T cells in transplantation tolerance

scientific article

Regulatory T cells in tumor immunity

scientific article published on August 2010

Regulatory T cells, derived from naïve CD4+CD25- T cells by in vitro Foxp3 gene transfer, can induce transplantation tolerance.

scientific article published in May 2005

Regulatory T cells: how do they suppress immune responses?

scientific article published on 07 September 2009

Regulatory T cells: mediating compromises between host and parasite

scientific article published in January 2003

Regulatory T cells: recommendations to simplify the nomenclature.

scientific article published in April 2013

Regulatory T cells: roles of T cell receptor for their development and function

scientific article published on 24 February 2010

Regulatory T-cell deficiency and autoimmune skin disease: Beyond the scurfy mouse and immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome

scholarly article by Takashi Hashimoto et al published September 2018 in The Journal of Allergy and Clinical Immunology

Regulatory T-cell directed therapies in liver diseases.

scientific article published on 29 May 2013

Regulatory cells in transplantation.

scientific article published on January 2003

Regulatory roles of IL-10-producing human follicular T cells

scientific article published on 17 June 2019

Reply to Slominski et al.: UVB irradiation induces proenkephalin<sup>+</sup> regulatory T cells with a wound-healing function

scientific article published on 01 January 2021

Requirement of protocol biopsy before and after complete cessation of immunosuppression after liver transplantation

scientific article published in February 2009

SKG arthritis as a model for evaluating therapies in rheumatoid arthritis with special focus on bone changes.

scientific article published on 5 September 2012

SLAP deficiency enhances number and function of regulatory T cells preventing chronic autoimmune arthritis in SKG mice

scientific article

Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation

scientific article published in Nature Communications

Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells

scientific article published on 03 June 2021

Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3high regulatory T cells in humans

scientific article published on 26 May 2015

Skin controls immune regulators

scientific article published on 01 December 2006

Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells

scientific article published in November 2017

Spontaneous development of autoimmune arthritis due to genetic anomaly of T cell signal transduction: Part 1.

scientific article

Spontaneous large-scale lymphoid neogenesis and balanced autoimmunity versus tolerance in the stomach of H+/K+-ATPase-reactive TCR transgenic mouse

scientific article published on 01 December 2006

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

scientific article

Stimulation of the glucocorticoid-induced TNF receptor family-related receptor on CD8 T cells induces protective and high-avidity T cell responses to tumor-specific antigens

scientific article

Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation

scientific article published on 24 April 2019

Synovial Tissue Inflammation Mediated by Autoimmune T Cells

scientific article published on 21 August 2019

Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice.

scientific article

Systemic targeting of CpG-ODN to the tumor microenvironment with anti-neu-CpG hybrid molecule and T regulatory cell depletion induces memory responses in BALB-neuT tolerant mice

scientific article published on September 2008

T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow.

scientific article published on February 2017

T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development

scientific article published on 01 November 2012

T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis.

scientific article published on 16 January 2007

T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man.

scientific article published on March 2012

TCR diversity and Treg cells, sometimes more is more.

scientific article published on 20 October 2011

TREG-cell therapies for autoimmune rheumatic diseases.

scientific article published on July 2014

Taming transplantation with T cells

scientific article published on 01 September 2003

Targeting Treg cells in cancer immunotherapy

scientific article published on 05 July 2019

Testosterone is protective in the sexually dimorphic development of arthritis and lung disease in SKG mice.

scientific article published on June 2013

The Long-Term Survival Potential of Mature T Lymphocytes Is Programmed During Development in the Thymus ⬇️

scientific article published on November 15, 2011

The Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-Analysis

scientific article

The dichotomous role of IL-2: tolerance versus immunity.

scientific article

The generation of donor-specific CD4+CD25++CD45RA+ naive regulatory T cells in operationally tolerant patients after pediatric living-donor liver transplantation

scientific article published in December 2010

The origin of FOXP3-expressing CD4+ regulatory T cells: thymus or periphery ⬇️

scientific article published on November 1, 2003

The plasticity and stability of regulatory T cells

scientific article published on 17 May 2013

The presence of Foxp3 expressing T cells within grafts of tolerant human liver transplant recipients

The role of regulatory T cells in controlling immunologic self-tolerance

scientific article published on January 1, 2003

Theoretical modeling reveals that regulatory T cells increase T-cell interaction with antigen-presenting cells for stable immune tolerance

scientific article published on 01 October 2019

Therapeutic approaches to allergy and autoimmunity based on FoxP3+ regulatory T-cell activation and expansion

scientific article published on April 2009

Therapeutic glucocorticoid-induced TNF receptor-mediated amplification of CD4+ T cell responses enhances antiparasitic immunity

scientific article published on 5 February 2010

Therapeutic immunity by adoptive tumor-primed CD4(+) T-cell transfer in combination with in vivo GITR ligation

scientific article published on 05 May 2009

Thymic generation and selection of CD25+CD4+ regulatory T cells: implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance

scientific article published on January 1, 2003

Thymus, innate immunity and autoimmune arthritis: Interplay of gene and environment ⬇️

scientific article published on October 21, 2011

Transcriptional and Epigenetic Control of Regulatory T Cell Development

scientific article

Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases

scientific article published on 04 May 2020

Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancer

scientific article published on 6 June 2014

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells.

scientific article

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3CD25CD4 regulatory T cells

scientific article published in February 2012

Treg Cells Acquire New Directions, Cytokines Navigate ⬇️

scientific article published on September 21, 2012

Tumour grade significantly correlates with total dysfunction of tumour tissue-infiltrating lymphocytes in renal cell carcinoma

scientific article published on 10 April 2020

Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers

scientific article

Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals.

scientific article

Two modes of immune suppression by Foxp3(+) regulatory T cells under inflammatory or non-inflammatory conditions

scientific article

Tyrosine kinase inhibitor imatinib augments tumor immunity by depleting effector regulatory T cells

scientific article published on 01 February 2020

UVB Exposure Prevents Atherosclerosis by Regulating Immunoinflammatory Responses.

scientific article published on 20 October 2016

Ultraviolet B-Induced Maturation of CD11b-Type Langerin- Dendritic Cells Controls the Expansion of Foxp3+ Regulatory T Cells in the Skin

scientific article published on 20 November 2017

Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells

scientific article

Utility of CD127 combined with FOXP3 for identification of operational tolerance after liver transplantation

scientific article published on 19 April 2016

VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data

scientific article published on 10 May 2020

VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data

scientific article published on 05 October 2020

Value of FOXP3 expression in peripheral blood as rejection marker after miniature swine lung transplantation

scientific article

[Aetiology of rheumatoid arthritis]

scientific article published on 01 September 2005

[Etiology of rheumatoid arthritis in an animal model]

scientific article published on 01 December 2002

[Liver transplantation]

scientific article published on 01 April 2005

[Peripheral tolerance to allergen mediated by regulatory T cells]

scientific article published on 01 November 2009

[Regulatory T cell and autoimmune diseases]

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