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List of works by Helen Heslop

"Mini" bank of only 8 donors supplies CMV-directed T cells to diverse recipients

scientific article published on 01 September 2019

A backpack revs up T-cell activity

scientific article published on 01 August 2018

A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells

scientific article published on 23 June 2005

A less sour sweet; blocking galectin ⬇️

scientific article published on April 21, 2011

A method for preparing leucocyte depleted erythrocytes from rat blood ⬇️

scientific article published on January 1, 1978

A phase 2/3 multicenter randomized clinical trial of ABX-CBL versus ATG as secondary therapy for steroid-resistant acute graft-versus-host disease

scientific article

A phase I clinical trial of recombinant interleukin 2 following high dose chemo-radiotherapy for haematological malignancy: applicability to the elimination of minimal residual disease

scientific article

A single institution experience with pediatric nasopharyngeal carcinoma: high incidence of toxicity associated with platinum-based chemotherapy plus IMRT.

scientific article published in July 2007

A strategy for treatment of Epstein-Barr virus-positive Hodgkin's disease by targeting interleukin 12 to the tumor environment using tumor antigen-specific T cells

scientific article published on February 2004

ASBMT committee report: white paper on measurement of quality outcomes

scientific article published on 01 May 2006

Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex).

scientific article

Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT.

scientific article

Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity.

scientific article

Add-back of allodepleted donor T cells to improve immune reconstitution after haplo-identical stem cell transplantation

scientific article

Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to LMP2A antigen: a potential treatment strategy for Epstein-Barr virus--positive Hodgkin's lymphoma

scientific article published in September 2001

Adenovirus infection after pediatric bone marrow transplantation

scientific article

Adenovirus infection rates in pediatric recipients of alternate donor allogeneic bone marrow transplants receiving either antithymocyte globulin (ATG) or alemtuzumab (Campath).

scientific article

Administration of latent membrane protein 2-specific cytotoxic T lymphocytes to patients with relapsed Epstein-Barr virus-positive lymphoma

scientific article published in January 2006

Administration of neomycin resistance gene marked EBV specific cytotoxic T-lymphocytes to patients with relapsed EBV-positive Hodgkin disease.

scientific article published on May 1998

Administration of neomycin resistance gene-marked EBV-specific cytotoxic T-lymphocytes as therapy for patients receiving a bone marrow transplant for relapsed EBV-positive Hodgkin disease

scientific article published on July 2000

Administration of neomycin-resistance-gene-marked EBV-specific cytotoxic T lymphocytes to recipients of mismatched-related or phenotypically similar unrelated donor marrow grafts

scientific article published on March 1994

Adoptive Immunotherapy with Antigen-Specific T Cells Expressing a Native TCR

scientific article published on 01 April 2019

Adoptive T cell therapy of cancer

scientific article

Adoptive T-cell therapy for EBV-associated post-transplant lymphoproliferative disease

scientific article published on January 2003

Adoptive T-cell therapy for Epstein-Barr virus-positive Hodgkin's disease

scientific article published on January 2003

Adoptive T-cell transfer in cancer immunotherapy

scientific article

Adoptive cellular immunotherapy for EBV lymphoproliferative disease

scientific article published on June 1997

Adoptive cellular immunotherapy for viral diseases

scientific article published on 5 November 2007

Adoptive cellular therapy with T cells specific for EBV-derived tumor antigens

scientific article published on March 2008

Adoptive immunotherapy for EBV-associated malignancies

scientific article published on 01 January 2005

Adoptive immunotherapy for Epstein-Barr virus-related lymphoma

scientific article published on October 1996

Adoptive immunotherapy for posttransplantation viral infections

scientific article published on March 2004

Adoptive immunotherapy for primary immunodeficiency disorders with virus-specific T lymphocytes

scientific article (publication date: May 2016)

Adoptive immunotherapy of EBV-associated malignancies with EBV-specific cytotoxic T-cell lines

scientific article

Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation

scientific article

Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma

scientific article

Adoptive transfer of rapidly-generated multivirus-specific T cells to treat Adv, EBV, CMV, BK and HHV6 infections of HSCT recipients

scientific article published on 7 November 2013

Adverse events following infusion of T cells for adoptive immunotherapy: a 10-year experience

scientific article

Aggressive peripheral CD70-positive T-cell lymphoma associated with severe chronic active EBV infection

scientific article published on 12 October 2011

Allogeneic bone marrow transplantation for children with histiocytic disorders: use of TBI and omission of etoposide in the conditioning regimen

scientific article published in June 2003

Allogeneic bone marrow transplantation in children failing prior autologous bone marrow transplantation

scientific article

Allogeneic haematopoietic cell transplantation for myelofibrosis in 30 patients 60–78 years of age ⬇️

scientific article published on February 17, 2011

Allogeneic hematopoietic stem cell transplant for relapsed and refractory non-Hodgkin lymphoma in pediatric patients

scientific article published on 01 September 2019

Allogeneic virus-specific T cells with HLA alloreactivity do not produce GVHD in human subjects

scientific article

An Epstein-Barr virus deletion mutant associated with fatal lymphoproliferative disease unresponsive to therapy with virus-specific CTLs

scientific article

An inducible caspase 9 safety switch for T-cell therapy

scientific article published on 22 February 2005

An inducible caspase 9 suicide gene to improve the safety of mesenchymal stromal cell therapies

scientific article published on June 2010

Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma

scientific article published on 23 July 2020

Anti-pan T lymphocyte ricin A chain immunotoxin (H65-RTA) and methylprednisolone for acute GVHD prophylaxis following allogeneic BMT from HLA-identical sibling donors

scientific article published on 01 January 1993

Antigen-specific T cell therapies for cancer

scientific article published on 09 July 2015

Antigen-specific cytotoxic T lymphocytes can target chemoresistant side-population tumor cells in Hodgkin lymphoma

scientific article

Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma

scientific article published on 7 October 2011

Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-beta receptor

scientific article

Antiviral T-cell therapy

scientific article

Assessing the safety of cytotoxic T lymphocytes transduced with a dominant negative transforming growth factor-beta receptor.

scientific article published in May 2006

Assessment of the efficacy of purging by using gene marked autologous marrow transplantation for children with AML in first complete remission

scientific article published on 01 April 1994

Autologous Epstein-Barr virus (EBV)-specific cytotoxic T cells for the treatment of persistent active EBV infection

scientific article published on August 2002

Autologous HER2 CMV bispecific CAR T cells are safe and demonstrate clinical benefit for glioblastoma in a Phase I trial

scientific article published on 4 November 2015

Biology and treatment of Epstein-Barr virus-associated non-Hodgkin lymphomas

scientific article

Blood and Marrow Transplant Clinical Trials Network State of the Science Symposium 2007

scientific article published on 01 November 2007

Blood and marrow transplant clinical trials network state of the Science Symposium 2014

scientific article published on 15 October 2014

Bone marrow transplantation for therapy-induced acute myeloid leukemia in children with previous lymphoid malignancies

scientific article

Bronchiolitis obliterans organizing pneumonia (BOOP) in children after allogeneic bone marrow transplantation

scientific article published on February 1994

CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma

scientific article published on 8 June 2017

CAR-T Cell Therapy for Lymphoma.

scientific article published on 26 August 2015

CAR-T cell Therapy for Non-Hodgkin Lymphomas: A New Treatment Paradigm

scientific article published on 28 March 2019

CARs on track in the clinic

scientific article

CD20 monoclonal antibody (rituximab) for therapy of Epstein-Barr virus lymphoma after hemopoietic stem-cell transplantation

scientific article published in February 2000

CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients

scientific article

CD52 and CD45 monoclonal antibodies for reduced intensity hemopoietic stem cell transplantation from HLA matched and one antigen mismatched unrelated donors

scientific article published in June 2005

CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo

scientific article published on April 2015

CRISPR-Edited Immune Effectors: The End of the Beginning

scientific article published on 22 March 2020

Cellular immunity to Epstein-Barr virus in liver transplant recipients treated with rituximab for post-transplant lymphoproliferative disease

scientific article

Cellular therapy of Epstein-Barr-virus-associated post-transplant lymphoproliferative disease

scientific article published in September 2004

Characteristics of T-cell receptor repertoire and myelin-reactive T cells reconstituted from autologous haematopoietic stem-cell grafts in multiple sclerosis

scientific article published on 25 February 2004

Characterization and treatment of chronic active Epstein-Barr virus disease: a 28-year experience in the United States

scientific article

Characterization of latent membrane protein 2 specificity in CTL lines from patients with EBV-positive nasopharyngeal carcinoma and lymphoma

scientific article published in September 2005

Checkpoint inhibition and cellular immunotherapy in lymphoma

scientific article published on December 2016

Children with acute leukemia: A comparison of outcomes from allogeneic blood stem cell and bone marrow transplantation ⬇️

scientific article published on January 1, 2011

Clinical Utilization of Chimeric Antigen Receptor T Cells in B Cell Acute Lymphoblastic Leukemia: An Expert Opinion from the European Society for Blood and Marrow Transplantation and the American Society for Blood and Marrow Transplantation

scientific article published on 18 December 2018

Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes

scientific article published on 14 August 2017

Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS post-allogeneic transplant

scientific article published on 03 December 2020

Clinical responses with T lymphocytes targeting malignancy-associated κ light chains

scientific article published on 06 June 2016

Clinical utilization of Chimeric Antigen Receptor T-cells (CAR-T) in B-cell acute lymphoblastic leukemia (ALL)-an expert opinion from the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Tran

scientific article published on 15 May 2019

Clonal Dynamics In Vivo of Virus Integration Sites of T Cells Expressing a Safety Switch

scientific article

Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15

scientific article

Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes.

scientific article

Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma.

scientific article published on 13 August 2013

Combining drugs and biologics to treat nasopharyngeal cancer

scientific article published on January 2014

Commentary on journal of immunotherapy paper by melenhorst et al

scientific article published on 01 July 2006

Comparable outcome of alternative donor and matched sibling donor hematopoietic stem cell transplant for children with acute lymphoblastic leukemia in first or second remission using alemtuzumab in a myeloablative conditioning regimen

scientific article

Comparable outcomes of matched-related and alternative donor stem cell transplantation for pediatric severe aplastic anemia

scientific article published in December 2006

Comparison of the efficiency of transduction of leukemic cells by fiber-modified adenoviruses.

scientific article published on December 2004

Comparison of two CD40-ligand/interleukin-2 vaccines in patients with chronic lymphocytic leukemia ⬇️

scientific article published on July 12, 2011

Complement-fixing CD45 monoclonal antibodies to facilitate stem cell transplantation in mouse and man.

scientific article published in May 2003

Complementation of antigen-presenting cells to generate T lymphocytes with broad target specificity

scientific article

Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer

scientific article

Computer-assisted quantitative evaluation of therapeutic responses for lymphoma using serial PET/CT imaging

scientific article

Control of virus-induced lymphoproliferation: Epstein-Barr virus-induced lymphoproliferation and host immunity

scientific article published on January 1997

Correction of Duncan's syndrome by allogeneic bone marrow transplantation

scientific article published on 01 September 1993

Crosstalk between Medulloblastoma Cells and Endothelium Triggers a Strong Chemotactic Signal Recruiting T Lymphocytes to the Tumor Microenvironment ⬇️

scientific article published on May 27, 2011

Current Allogeneic Hematopoietic Stem Cell Transplantation for Pediatric Acute Lymphocytic Leukemia: Success, Failure and Future Perspectives-A Single-Center Experience, 2008 to 2016.

scientific article

Current status of genetic modification of T cells for cancer treatment

scientific article

Cytomegalovirus (CMV) infections and CMV-specific cellular immune reconstitution following reduced intensity conditioning allogeneic stem cell transplantation with Alemtuzumab

scientific article

Cytotoxic T lymphocyte therapy for Epstein-Barr virus+ Hodgkin's disease

scientific article

Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation

scientific article published on 21 August 2009

Cytotoxic T lymphocytes as immune-therapy in haematological practice

scientific article

Cytotoxic T lymphocytes directed to the preferentially expressed antigen of melanoma (PRAME) target chronic myeloid leukemia

scientific article

Cytotoxic T lymphocytes simultaneously targeting multiple tumor-associated antigens to treat EBV negative lymphoma

scientific article

Definitions of histocompatibility typing terms ⬇️

scientific article published on October 14, 2011

Definitions of histocompatibility typing terms: Harmonization of Histocompatibility Typing Terms Working Group ⬇️

scientific article published on June 15, 2011

Delayed Induction of Proto-Oncogene Expression in B-CLL Cells by Tumor Necrosis Factor

scientific article

Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation

scientific article

Diagnosis and treatment of posttransplantation lymphoproliferative disease after hematopoietic stem cell transplantation

scientific article

Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells.

scientific article

Donor T cells to treat EBV-associated lymphoma

scientific article published on 01 September 1994

EBV specific CTL: a model for immune therapy

scientific article published in January 1998

EBV/LMP-specific T cells maintain remissions of T- and B-cell EBV lymphomas after allogeneic bone marrow transplantation

scientific article published on 27 September 2018

Early identification of Epstein-Barr virus-associated post-transplantation lymphoproliferative disease

scientific article

Effects of interferon alpha on autocrine growth factor loops in B lymphoproliferative disorders

scientific article

Effects of recombinant interleukin-2 administration on cytotoxic function following high-dose chemo-radiotherapy for hematological malignancy

scientific article published on 01 November 1989

Effects of tumour necrosis factor and alpha interferon on chronic B cell malignancies

scientific article published on 01 January 1988

Efficacy of deferred dosing of granulocyte colony-stimulating factor in autologous hematopoietic transplantation for multiple myeloma.

scientific article published on 07 October 2013

Efficient infection of primitive hematopoietic stem cells by modified adenovirus

scientific article published in June 2001

Endogenously generated activated killer cells circulate after autologous and allogeneic marrow transplantation but not after chemotherapy

scientific article published on 01 April 1989

Energy expenditure in children undergoing hematopoietic stem cell transplantation

scientific article published in July 2002

Engineered off-the-shelf therapeutic T cells resist host immune rejection

scientific article published on 13 July 2020

Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety

scientific article published on 29 April 2010

Enhancement of monoclonal antibody dependent cell mediated cytotoxicity by IL2 and GM-CSF

scientific article published on 01 December 1989

Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients

scientific article published on 29 October 2008

Epigenetic Inhibition Puts Target Antigen in the Crosshairs of CAR T Cells

scientific article published on 18 April 2019

Epipodophyllotoxin-related acute myeloid leukemia: a study of 35 cases

scientific article published on 01 December 1995

Epstein Barr virus specific cytotoxic T lymphocytes expressing the anti-CD30zeta artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease

scientific article

Epstein-Barr infection after bone marrow transplantation

scientific article published on 01 March 1994

Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the prevention and treatment of EBV-associated post-transplant lymphomas

scientific article published on January 2002

Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the treatment of patients with EBV-positive relapsed Hodgkin's disease ⬇️

scientific article published on April 15, 1998

Epstein-Barr virus lymphoproliferative disease after hematopoietic stem cell transplant

scientific article

Equal opportunity CAR T cells

scientific article

Equal-opportunity treatment of EBV-PTLD ⬇️

scientific article published on March 15, 2012

Evidence for the presentation of major histocompatibility complex class I-restricted Epstein-Barr virus nuclear antigen 1 peptides to CD8+ T lymphocytes

scientific article

Ex vivo gene transfer for improved adoptive immunotherapy of cancer

scientific article published on 17 March 2011

Excellent survival after sibling or unrelated donor stem cell transplantation for chronic granulomatous disease

scientific article published on 12 November 2011

Exhausting alloreactivity of donor-derived CAR T cells

scientific article published in February 2017

Expansion of EBV latent membrane protein 2a specific cytotoxic T cells for the adoptive immunotherapy of EBV latency type 2 malignancies: influence of recombinant IL12 and IL15

scientific article published on 01 January 2003

Expansion of T cells targeting multiple antigens of cytomegalovirus, Epstein-Barr virus and adenovirus to provide broad antiviral specificity after stem cell transplantation

scientific article published on 4 May 2011

Exploiting cytokine secretion to rapidly produce multivirus-specific T cells for adoptive immunotherapy

scientific article published on September 2008

Fall of the mutants: T cells targeting BCR-ABL.

scientific article published on February 2017

Fine-tuning the CAR spacer improves T-cell potency

scientific article published on 8 November 2016

Flanking-sequence exponential anchored-polymerase chain reaction amplification: a sensitive and highly specific method for detecting retroviral integrant-host-junction sequences

scientific article

Forecasting Cytokine Storms with New Predictive Biomarkers

scientific article

Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes

scientific article published on 14 May 2009

Gamma delta T lymphocyte regeneration after T lymphocyte-depleted bone marrow transplantation from mismatched family members or matched unrelated donors

scientific article published on 01 February 1996

Gamma-interferon and tumor necrosis factor production after bone marrow transplantation is augmented by exposure to marrow fibroblasts infected with cytomegalovirus

scientific article published on 01 September 1990

Gene and cell transfer for specific immunotherapy

scientific article published in January 1998

Gene marking after bone marrow transplantation.

scientific article

Gene marking and autologous bone marrow transplantation

scientific article published on May 1994

Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients

scientific article published on 01 November 1993

Gene therapy for paediatric leukaemia ⬇️

scientific article published on July 1, 2001

Gene transfer and bone marrow transplantation

scientific article published on 01 January 1994

Gene transfer into human hemopoietic progenitor cells

scientific article published on January 1995

Gene-marked autologous hematopoietic stem cell transplantation of autoimmune disease

scientific article

Gene-marking and haemopoietic stem-cell transplantation

scientific article published on December 1995

Gene-marking studies of hematopoietic cells

scientific article

Generating CTLs against the subdominant Epstein-Barr virus LMP1 antigen for the adoptive immunotherapy of EBV-associated malignancies

scientific article published on 31 October 2002

Generation of EBV-specific CD4+ cytotoxic T cells from virus naive individuals

scientific article

Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506)

scientific article published on 16 September 2009

Generation of autologous Epstein-Barr virus-specific cytotoxic T cells for adoptive immunotherapy in solid organ transplant recipients

scientific article

Generation of multivirus-specific T cells by a single stimulation of peripheral blood mononuclear cells with a peptide mixture using serum-free medium

scientific article published on 17 August 2018

Generation of polyclonal CMV-specific T cells for the adoptive immunotherapy of glioblastoma

scientific article published on February 2012

Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis.

scientific article published on 9 April 2018

Genetic engineering of T-cell receptors: TCR takes to titin ⬇️

scientific article published on August 8, 2013

Genetic manipulation of tumor-specific cytotoxic T lymphocytes to restore responsiveness to IL-7.

scientific article published on 3 March 2009

Genetic modification of T cells

scientific article

Genetically engineered T-cells for adoptive immunotherapy.

scientific article

Getting Personal with Melanoma ⬇️

scientific article published on June 28, 2011

Go-CART: an animal-free system for the assessment of CAR T cell function.

scientific article published on 4 November 2015

Graft versus leukaemia effects after marrow transplantation in man.

scientific article published on July 1991

Graft versus leukemia response without graft-versus-host disease elicited by adoptively transferred multivirus-specific T-cells

scientific article published on 30 September 2014

Graft-versus-host reactions and bone-marrow transplantation ⬇️

scientific article published on October 1, 1991

Guidance for developing phase II cell therapy trial proposals for consideration by the Blood and Marrow Transplant Clinical Trials Network

scientific article

Guillain-Barré syndrome after allogeneic hematopoietic stem cell transplantation

scientific article

HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial

scientific article published on 20 April 2017

HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors

scientific article published on 12 January 2010

Haemopoietic stem cell transplantation for acute lymphoblastic leukaemia

scientific article

Harmonizing Immune Effector Toxicity Reporting

scientific article published on 05 January 2019

Hematopoietic and immunomodulatory effects of lytic CD45 monoclonal antibodies in patients with hematologic malignancy

scientific article published on 01 April 2003

Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosis

scientific article published on October 2008

Hemolytic uremic syndrome after bone marrow transplantation: clinical characteristics and outcome in children

scientific article

Hemorrhagic cystitis after allogeneic bone marrow transplantation in children: clinical characteristics and outcome

scientific article

High Incidence of Autoimmune Disease after Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease

scientific article published on 6 April 2018

High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells

scientific article

Homeostatic action of interleukin-4 on endogenous and recombinant interleukin-2-induced activated killer cell function

scientific article published on 01 March 1991

How I treat EBV lymphoproliferation

scientific article published on September 2009

Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma

scientific article published on 23 March 2015

Human gene marker/therapy clinical protocols

scientific article published on 01 August 1996

Human gene marker/therapy clinical protocols

scientific article published on 01 December 1996

Human gene marker/therapy clinical protocols

scientific article published on 01 December 1999

Human gene marker/therapy clinical protocols

scientific article published on 01 April 2000

Human gene marker/therapy clinical protocols

scientific article published on 01 December 1997

Human herpesvirus-6 encephalitis following allogeneic hematopoietic stem cell transplantation

scientific article published on 2 April 2007

Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes for adoptive immunotherapy of HPV-associated malignancies.

scientific article

IL-2 infusion abrogates humoral immune responses in humans

scientific article published in March 1992

Identification of HLA-DP3-restricted peptides from EBNA1 recognized by CD4(+) T cells.

scientific article published in December 2002

Identification of hexon-specific CD4 and CD8 T-cell epitopes for vaccine and immunotherapy

scientific article

Immune therapy for EBV infections after hemopoietic stem-cell transplant

scientific article

Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation

scientific article

Immunotherapy for Epstein-Barr virus-associated cancers

scientific article published in January 1998

Immunotherapy for Epstein-Barr virus-associated cancers in children

scientific article

Immunotherapy for Hodgkin's disease.

scientific article published on January 2002

Immunotherapy for epstein-barr virus-related lymphomas ⬇️

scientific article published on November 17, 2009

Immunotherapy for osteosarcoma: genetic modification of T cells overcomes low levels of tumor antigen expression.

scientific article

Immunotherapy for post-transplant lymphoproliferative disease

scientific article

Immunotherapy of hematologic malignancy.

scientific article published on January 2003

Immunotherapy of high-risk acute leukemia with a recipient (autologous) vaccine expressing transgenic human CD40L and IL-2 after chemotherapy and allogeneic stem cell transplantation.

scientific article published on 25 October 2005

Immunotherapy of leukemia

scientific article published in January 1992

Immunotherapy targeting EBV-expressing lymphoproliferative diseases

scientific article published on September 2008

Immunotherapy to reconstitute immunity to DNA viruses

scientific article

Immunotherapy: opportunities, risks and future perspectives

scientific article

Impending challenges in the hematopoietic stem cell transplantation physician workforce

scientific article published on 23 September 2009

Improving Chimeric Antigen Receptor-Modified T Cell Function by Reversing the Immunosuppressive Tumor Microenvironment of Pancreatic Cancer

scientific article published on 4 January 2017

Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4

scientific article published on 9 September 2011

In Vivo Fate and Activity of Second- versus Third-Generation CD19-Specific CAR-T Cells in B Cell Non-Hodgkin's Lymphomas

scientific article published on 13 September 2018

In vitro analysis of the interactions of recombinant IL-2 with regenerating lymphoid and myeloid cells after allogeneic marrow transplantation

scientific article published on 01 May 1988

In vivo expansion of LMP 1- and 2-specific T-cells in a patient who received donor-derived EBV-specific T-cells after allogeneic stem cell transplantation

scientific article published in May 2006

In vivo induction of gamma interferon and tumor necrosis factor by interleukin-2 infusion following intensive chemotherapy or autologous marrow transplantation

scientific article published on 01 September 1989

Incorporation of thiotepa in a reduced intensity conditioning regimen may improve engraftment after transplant for HLH

scientific article published on 27 January 2020

Increased transduction efficiency of primary hematopoietic cells by physical colocalization of retrovirus and target cells

scientific article published in June 1998

Increasing the purity, potency and specificity of ebv-specific T cells to improve the treatment of EBV-positive lymphoma

scientific article published on 4 November 2015

Inducible apoptosis as a safety switch for adoptive cell therapy

scientific article (publication date: 3 November 2011)

Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation

scientific article published on 29 May 2007

Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation

scientific article published on 14 May 2015

Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients ⬇️

scientific article published on September 1, 1998

Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study

scientific article published on 12 September 2013

Intensive chemotherapy with hematopoietic stem-cell support for children with recurrent or refractory NHL

scientific article published on 01 January 2002

Interleukin 15 provides relief to CTLs from regulatory T cell-mediated inhibition: implications for adoptive T cell-based therapies for lymphoma

scientific article published on 13 November 2012

Interleukin 2 infusion induces haemopoietic growth factors and modifies marrow regeneration after chemotherapy or autologous marrow transplantation

scientific article published on 01 February 1991

Interleukin-2 infusion after autologous bone marrow transplantation enhances hemopoietic regeneration

scientific article published on 01 February 1991

Intravenous Cidofovir therapy for disseminated adenovirus in a pediatric liver transplant recipient

scientific article published in October 2002

Is retroviral gene marking too dangerous to use?

scientific article published on 01 January 2003

Kinetics of tumor destruction by chimeric antigen receptor-modified T cells

scientific article published on 28 November 2013

Large-scale expansion of dendritic cell-primed polyclonal human cytotoxic T-lymphocyte lines using lymphoblastoid cell lines for adoptive immunotherapy

scientific article published on 01 May 2003

Late-onset severe chronic active EBV in a patient for five years with mutations in STXBP2 (MUNC18-2) and PRF1 (perforin 1).

scientific article published on 7 May 2015

Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene

scientific article

Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients

scientific article

Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes

scientific article published in May 1996

Lymphoproliferative disorders involving Epstein-Barr virus after hemopoietic stem cell transplantation

scientific article

Malignant plasma cells are sensitive to LAK cell lysis: pre-clinical and clinical studies of interleukin 2 in the treatment of multiple myeloma

scientific article published on August 1990

Modulating TNFα activity allows transgenic IL15-Expressing CLL-1 CAR T cells to safely eliminate acute myeloid leukemia

scientific article published on 01 September 2020

Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals

scientific article published on 24 September 2006

Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation

scientific article published on 22 April 2013

Neuropathic dermatomes and cutaneous ulceration in patients with chronic GVHD.

scientific article published on 28 April 2014

New ISSCR guidelines: clinical translation of stem cell research

scientific article published in The Lancet

New approaches in alternative donor transplantation

scientific article published on 27 October 2012

Nucleofection of DCs to generate Multivirus-specific T cells for prevention or treatment of viral infections in the immunocompromised host.

scientific article

Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation

scientific article published on 7 August 2017

Optimizing the production of suspension cells using the G-Rex "M" series

scientific article

Options for T-cell based therapies

scientific article published on July 2004

Outcome of hematopoietic stem cell transplant as salvage therapy for Hodgkin's lymphoma in adolescents and young adults at a single institution

scientific article published on April 2010

Outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation (RISCT) using antilymphocyte antibodies in patients with high-risk acute myeloid leukemia (AML)

scientific article published on 01 March 2006

Outcomes after Allogeneic Transplant in Patients with Wiskott-Aldrich Syndrome

scientific article published on 28 November 2017

Outcomes after Second Hematopoietic Stem Cell Transplantations in Pediatric Patients with Relapsed Hematological Malignancies

scientific article published on 10 March 2015

Outcomes of transplantation with matched-sibling and unrelateddonor bone marrow in children with leukaemia ⬇️

scientific article published on September 13, 1997

Pharmacotherapy versus T lymphocytes for CMV ⬇️

scientific article published on May 2, 2013

Phase I study of chemokine and cytokine gene-modified autologous neuroblastoma cells for treatment of relapsed/refractory neuroblastoma using an adenoviral vector

scientific article

Plasma Markers of B-Cell Activation and Clonality in Pediatric Liver and Hematopoietic Stem Cell Transplant Recipients ⬇️

scientific article published on February 15, 2013

Policy: Global standards for stem-cell research

scientific article

Possible mechanism of action of interferon alpha in chronic B-cell malignancies

scientific article published on October 1991

Possible mechanism of selective killing of myeloid leukemic blast cells by lymphokine-activated killer cells ⬇️

scientific article published on 01 May 1991

Post-transplant lymphoproliferative disorders

scientific article

Posttransplant lymphoproliferative disease following liver transplantation

scientific article published on June 2011

Preparing for growth: current capacity and challenges in hematopoietic stem cell transplantation programs

scientific article published on 16 February 2010

Priorities for Improving Outcomes for Nonmalignant Blood Diseases: A Report from the Blood and Marrow Transplant Clinical Trials Network

scientific article published on 05 February 2020

Production of genetically modified Epstein-Barr virus-specific cytotoxic T cells for adoptive transfer to patients at high risk of EBV-associated lymphoproliferative disease

scientific article published on April 1995

Production of good manufacturing practice-grade cytotoxic T lymphocytes specific for Epstein-Barr virus, cytomegalovirus and adenovirus to prevent or treat viral infections post-allogeneic hematopoietic stem cell transplant

scientific article published on January 2012

Prompt versus preemptive intervention for EBV lymphoproliferative disease

scientific article published on 29 January 2004

Psychological effects of bone marrow transplantation on children and adolescents: preliminary report of a longitudinal study

scientific article published on 01 June 1995

Quantification of a low cellular immune response to aid in identification of pediatric liver transplant recipients at high-risk for EBV infection

scientific article published in November 2006

Quantitative EBV viral loads and immunosuppression alterations can decrease PTLD incidence in pediatric liver transplant recipients

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Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases: the evolution from myeloablative to lymphoablative transplant regimens

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Rapidly generated multivirus-specific cytotoxic T lymphocytes for the prophylaxis and treatment of viral infections

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Recent advances in T-cell immunotherapy for haematological malignancies

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Reconstitution of adenovirus-specific cell-mediated immunity in pediatric patients after hematopoietic stem cell transplantation

scientific article published on 9 April 2007

Reconstitution of the T cell receptor alpha beta repertoire in recipients of allogeneic BMT

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Regression of experimental medulloblastoma following transfer of HER2-specific T cells

scientific article published in June 2007

Replication-competent retroviruses in gene-modified T cells used in clinical trials: is it time to revise the testing requirements?

scientific article published on February 2012

Reply to S. Yuan et al.

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Requirements for the adoptive transfer of antibody responses to a priming antigen in man.

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Response of steroid-resistant graft-versus-host disease to lymphoblast antibody CBL1 ⬇️

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Reversal of tumor immune inhibition using a chimeric cytokine receptor

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Robust T cell responses to aspergillosis in chronic granulomatous disease: implications for immunotherapy

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Robust and cost effective expansion of human regulatory T cells highly functional in a xenograft model of graft-versus-host disease

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Safer CARS.

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Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant

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Seek and You Will Not Find: Ending the Hunt for Replication-Competent Retroviruses during Human Gene Therapy

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Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression

scientific article published on 18 November 2009

Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses

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Selective elimination of a chemoresistant side population of B-CLL cells by cytotoxic T lymphocytes in subjects receiving an autologous hCD40L/IL-2 tumor vaccine

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Serial Activation of the Inducible Caspase 9 Safety Switch After Human Stem Cell Transplantation

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Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines

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Spontaneous and interleukin 2 induced secretion of tumour necrosis factor and gamma interferon following autologous marrow transplantation or chemotherapy

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Successful treatment of stem cell graft failure in pediatric patients using a submyeloablative regimen of campath-1H and fludarabine

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Survival outcomes of allogeneic hematopoietic cell transplants with EBV-positive or EBV-negative post-transplant lymphoproliferative disorder, A CIBMTR study

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Survivin-specific T cell receptor targets tumor but not T cells

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Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins

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Systemic inflammatory response syndrome after administration of unmodified T lymphocytes

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T cell receptor repertoire of CD4+ and CD8+ T cell subsets in the allogeneic bone marrow transplant recipient ⬇️

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T cell therapies

scientific article published on 01 January 2006

T cell therapy in allogeneic stem cell transplantation

scientific article published on January 2008

T cells for viral infections after allogeneic hematopoietic stem cell transplant

scientific article published on 20 May 2016

T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model.

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T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells

scientific article published on 22 August 2006

T lymphocytes targeting native receptors

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T-Cell Receptor Stimulation Enhances the Expansion and Function of CD19 Chimeric Antigen Receptor-Expressing T Cells

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T-cell immunotherapy for adenoviral infections of stem-cell transplant recipients

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T-cell immunotherapy: looking forward

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T-cell receptor sequencing demonstrates persistence of virus-specific T cells after antiviral immunotherapy

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T-cell therapy for viral infections

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T-cell therapy in the treatment of post-transplant lymphoproliferative disease

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T-cell-based therapies for malignancy and infection in childhood

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TCR expression; quantitative easing by CD3

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TNF and chronic B lymphoproliferative disorders

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TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy ⬇️

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The clone ranger?

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The costs and cost-effectiveness of allogeneic peripheral blood stem cell transplantation versus bone marrow transplantation in pediatric patients with acute leukemia

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The generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin disease

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The immunogenicity of virus-derived 2A sequences in immunocompetent individuals ⬇️

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The safety and clinical effects of administering a multiantigen-targeted T cell therapy to patients with multiple myeloma

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The t(9;22) translocation in Philadelphia-positive essential thrombocythaemia does not involve the T lymphocyte lineage

scientific article published on 01 January 1990

The use of chimeric antigen receptor T cells in patients with non-Hodgkin lymphoma

The use of cytotoxic t cells for the prevention and treatment of epstein-barr virus induced lymphoma in transplant recipients

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Transduction of CD34(+) and CD34(-)/lin(-) hemopoietic progenitors by lentivirus vectors

scientific article published in January 1999

Transfer of EBV-specific CTL to prevent EBV lymphoma post bone marrow transplant

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Transfer of marker genes into hemopoietic progenitor cells

scientific article published on September 1, 1996

Transfusion-related acute lung injury (TRALI) following allogeneic stem cell transplant for acute myeloid leukemia

scientific article published on January 2004

Transmission of integrated human herpesvirus-6 in allogeneic hematopoietic stem cell transplantation

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Treatment of Epstein-Barr virus lymphoproliferative disease after hematopoietic stem-cell transplantation with hydroxyurea and cytotoxic T-cell lymphocytes

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Treatment of Epstein-Barr virus-associated malignancies with specific T cells

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Treatment of nasopharyngeal carcinoma with Epstein-Barr virus--specific T lymphocytes

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Treatment of relapsed Hodgkin's disease using EBV-specific cytotoxic T cells

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Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific cytotoxic T lymphocytes (CTLs)

scientific article published on 11 July 2006

Treatment of steroid-refractory acute graft-versus-host disease with anti-CD147 monoclonal antibody ABX-CBL.

scientific article published in October 2001

Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs

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Tumor necrosis factor mediates autocrine growth inhibition in a chronic leukemia

scientific article published on 01 December 1989

Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma

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Tumor-Specific T-Cells Engineered to Overcome Tumor Immune Evasion Induce Clinical Responses in Patients With Relapsed Hodgkin Lymphoma

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Tumour necrosis factor as an autocrine tumour growth factor for chronic B-cell malignancies

scientific article published on 01 April 1988

Ultra low-dose IL-2 for GVHD prophylaxis after allogeneic hematopoietic stem cell transplantation mediates expansion of regulatory T cells without diminishing antiviral and antileukemic activity.

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Use of Chimeric Antigen Receptor T Cell Therapy in Clinical Practice for Relapsed/Refractory Aggressive B Cell Non-Hodgkin Lymphoma: An Expert Panel Opinion from the American Society for Transplantation and Cellular Therapy

scientific article published on 22 August 2019

Use of cytokine polymorphisms and Epstein-Barr virus viral load to predict development of post-transplant lymphoproliferative disorder in paediatric liver transplant recipients

scientific article published in May 2006

Use of double marking with retroviral vectors to determine rate of reconstitution of untreated and cytokine expanded CD34+ selected marrow cells in patients undergoing autologous bone marrow transplantation

scientific article published on 01 March 1996

Use of gene marking in bone marrow transplantation

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Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation

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Viral lymphomagenesis

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Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

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XomaZyme-CD5 immunotoxin in conjunction with partial T cell depletion for prevention of graft rejection and graft-versus-host disease after bone marrow transplantation from matched unrelated donors

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