List of works - Emmanuelle Charpentier

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

scientific article

A Two-Component Regulatory System Impacts Extracellular Membrane-Derived Vesicle Production in Group A Streptococcus

scientific article (publication date: November 2016)

A crucial role for Lyn in TIMP-1 erythroid cell survival signalling pathway

scientific article published on 11 April 2013

A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum

scientific article

Adaptation in CRISPR-Cas Systems

scientific article published on 2 March 2016

Adopt a moratorium on heritable genome editing

scientific article published on 01 March 2019

Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes

scientific article published on 26 April 2016

An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3'-to-5' exoRNases and RNase Y

scientific article published on 27 March 2020

An outbreak of rubella in the Federation of Bosnia and Herzegovina between December 2009 and May 2010 indicates failure to vaccinate during wartime (1992–1995) ⬇️

scientific article published on April 28, 2011

An overview of RNAs with regulatory functions in gram-positive bacteria

scientific article published on 27 October 2009

An updated evolutionary classification of CRISPR-Cas systems

scientific article

Antibiotic resistance in Listeria spp.

scientific article

Bacterial flagella grow through an injection-diffusion mechanism

scientific article published on 06 March 2017

Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity

scientific article

Biotechnology: Rewriting a genome

scientific article published in March 2013

Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches

scientific article published on 02 March 2020

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

scientific article

CRISPR germline engineering--the community speaks

scientific article published on May 2015

CRISPR-Cas in Streptococcus pyogenes

scientific article published on 11 March 2019

CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo

scientific article published on June 2017

CRISPR-Cas9: how research on a bacterial RNA-guided mechanism opened new perspectives in biotechnology and biomedicine

scientific article published on 21 March 2015

CRISPR-Cas: biology, mechanisms and relevance

scientific article

CRISPR-Cas: more than ten years and still full of mysteries

scientific article published on 01 April 2019

Candida bloodstream infection in patients with systemic autoimmune diseases

scientific article published on 26 February 2020

Catalytically Active Cas9 Mediates Transcriptional Interference to Facilitate Bacterial Virulence

scientific article published on 27 June 2019

Characterization of a new class of tetracycline-resistance gene tet(S) in Listeria monocytogenes BM4210.

scientific article

Characterization of a transcriptional TPP riboswitch in the human pathogen Neisseria meningitidis

scientific article published on 20 February 2020

Classification and evolution of type II CRISPR-Cas systems

scientific article

Comparative impact of standard approach, FDG PET and FDG dual-head coincidence gamma camera imaging in preoperative staging of patients with non-small-cell lung cancer

scientific article published in December 2003

Conjugative Mobilization of the Rolling-Circle Plasmid pIP823 from Listeria monocytogenes BM4293 among Gram-Positive and Gram-Negative Bacteria.

scientific article published in August 1999

Conjugative mobilization of the rolling-circle plasmid pIP823 from Listeria monocytogenes BM4293 among gram-positive and gram-negative bacteria

scientific article

Control of laser treatment of 58 cervical condylomas: cyto-colposcopic correlations at 3, 6 and 12 months

scientific article

Control of membrane barrier during bacterial type-III protein secretion

scientific article published on 28 June 2021

DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes

scientific article published on 30 April 2015

Detection of a new subgenotype of hepatitis B virus genotype A in Cameroon but not in neighbouring Nigeria

scientific article

Distinct Polysaccharide Utilization Determines Interspecies Competition between Intestinal Prevotella spp

scientific article published on 13 October 2020

Dynamin inhibition interferes with inflammasome activation and cytokine gene expression in Streptococcus pyogenes-infected human macrophages

scientific article published on November 2014

Editorial overview: Novel technologies in microbiology: Recent advances in techniques in microbiology

scientific article published on 01 June 2014

Editorial: RNA in bacteria: biogenesis, regulatory mechanisms and functions

scientific article published on May 2015

Emergence of the trimethoprim resistance gene dfrD in Listeria monocytogenes BM4293.

scientific article

Emergence of vancomycin tolerance in Streptococcus pneumoniae

scientific article published in June 1999

Engineering of temperature- and light-switchable Cas9 variants

scientific article (publication date: 16 November 2016)

Ethoxyfagaronine, a synthetic analogue of fagaronine that inhibits vascular endothelial growth factor-1, as a new anti-angiogeneic agent.

scientific article published on 19 November 2014

Evolution and classification of the CRISPR-Cas systems

scientific article (publication date: June 2011)

Evolution of polyvalent intravenous immunoglobulins (IVIg) prescription, at the Assistance Publique - Hopitaux de Paris between 1988 and 1997. Results of the plan of action set up in order to regulate the prescription

scientific article published in May 2000

Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants

scientific article published on 19 December 2019

Extracellular Vesicle RNA: A Universal Mediator of Microbial Communication?

scientific article published on 13 March 2018

Extracellular targeting of choline-binding proteins in Streptococcus pneumoniae by a zinc metalloprotease

scientific article published on April 2000

Finding Her Niche: An Interview with Emmanuelle Charpentier

scientific article published on 01 February 2019

Functional Diversity of AAA+ Protease Complexes in Bacillus subtilis

scientific article

Functional analysis of the group A streptococcal luxS/AI-2 system in metabolism, adaptation to stress and interaction with host cells

scientific article

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

scientific article

Group A streptococcus activates type I interferon production and MyD88-dependent signaling without involvement of TLR2, TLR4, and TLR9.

scientific article published on 14 May 2008

Harnessing CRISPR-Cas9 immunity for genetic engineering

scientific article (publication date: June 2014)

Hypothesis: RNA and DNA Viral Sequence Integration into the Mammalian Host Genome Supports Long-Term B Cell and T Cell Adaptive Immunity

scientific article

Identification of a Streptococcus pneumoniae gene locus encoding proteins of an ABC phosphate transporter and a two-component regulatory system

scientific article

Identification of endoribonuclease specific cleavage positions reveals novel targets of RNase III in Streptococcus pyogenes

scientific article

Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase

scientific article (publication date: 2 December 2016)

In vivo 3'-to-5' exoribonuclease targetomes of

article published in the Proceedings of the National Academy of Sciences of the United States of America

Incidence of antibiotic resistance in Listeria species.

scientific article published in July 1995

Insertion sequence 1515 in the ply gene of a type 1 clinical isolate of Streptococcus pneumoniae abolishes pneumolysin expression

scientific article published on 9 May 2007

Low-density lipoprotein receptor-related protein-1 mediates endocytic clearance of tissue inhibitor of metalloproteinases-1 and promotes its cytokine-like activities

scientific article

Lysogenic transfer of group A Streptococcus superantigen gene among Streptococci

scientific article

Management of cranial-injured patients in the era of the Emergency Medical Service and the scanner. Comparative epidemiologic study with a 12-year interval in the same department of neurosurgery, in the Paris region

scientific article published in January 1986

McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR

scientific article

Mechanisms of antibiotic resistance and tolerance in Streptococcus pneumoniae

scientific article

Memory of viral infections by CRISPR-Cas adaptive immune systems: acquisition of new information

scientific article

Multicentre study to determine the Etest epidemiological cut-off values of antifungal drugs in Candida spp. and Aspergillus fumigatus species complex

scientific article published on 11 May 2019

Novel cassette-based shuttle vector system for gram-positive bacteria

scientific article published on October 2004

Penicillin tolerance genes ofStreptococcus pneumoniae: the ABC‐type manganese permease complex Psa ⬇️

scientific article published on September 1, 1998

Performance evaluation of different strategies based on microscopy techniques, rapid diagnostic test and molecular loop-mediated isothermal amplification assay for the diagnosis of imported malaria

scientific article published on 31 May 2019

Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems

scientific article

Plakoglobin suppresses epithelial proliferation and hair growth in vivo

scientific article

Presence of the Listeria tetracycline resistance gene tet(S) in Enterococcus faecalis

scientific article

RNA sequencing uncovers antisense RNAs and novel small RNAs in Streptococcus pyogenes

scientific article (publication date: 2016)

RNA techniques for bacteria

scientific article published on 15 June 2007

RNase Y-mediated regulation of the streptococcal pyrogenic exotoxin B

scientific article published on 18 October 2018

Refined sgRNA efficacy prediction improves large- and small-scale CRISPR-Cas9 applications

scientific article

Regulation of growth inhibition at high temperature, autolysis, transformation and adherence in Streptococcus pneumoniae by clpC.

scientific article

Role of JNK/ATF-2 pathway in inhibition of thrombospondin-1 (TSP-1) expression and apoptosis mediated by doxorubicin and camptothecin in FTC-133 cells ⬇️

scientific article published on February 17, 2011

Should pulp chamber pulpotomy be seen as a permanent treatment? Some preliminary thoughts ⬇️

scientific article published on August 20, 2012

Signal transduction by a death signal peptide: uncovering the mechanism of bacterial killing by penicillin

scientific article published in January 2000

Small RNAs in streptococci

scientific article

Spotlight on… Emmanuelle Charpentier

scientific article published on 30 January 2018

Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria

scientific article

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

scientific article

Switchable Cas9.

scientific article published on 26 April 2017

Synthesis of group A streptococcal virulence factors is controlled by a regulatory RNA molecule

scientific article published in September 2004

Targeting focal adhesion assembly by ethoxyfagaronine prevents lymphoblastic cell adhesion to fibronectin ⬇️

scientific article published on January 1, 2012

The Biology of CRISPR-Cas: Backward and Forward

scientific article published in March 2018

The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.

scientific article

The anti-invasive activity of synthetic alkaloid ethoxyfagaronine on L1210 leukemia cells is mediated by down-regulation of plasminogen activators and MT1-MMP expression and activity

scientific article published on 28 March 2010

The dark side of the salad: Salmonella typhimurium overcomes the innate immune response of Arabidopsis thaliana and shows an endopathogenic lifestyle

scientific article

The mystery of psaA and penicillin tolerance in Streptococcus pneumoniae

scientific article published on 01 June 2000

The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems

scientific article

Toward Whole-Transcriptome Editing with CRISPR-Cas9.

scientific article published on May 2015

Toxin‐Gene Profile Heterogeneity among Endemic Invasive European Group A Streptococcal Isolates ⬇️

scientific article published on November 5, 2003

[Autosomal dominant polycystic kidney in adults and transplantation]

scientific article published on 01 January 1990

[Congestive heart failure: Treatment with ultrafiltration].

scientific article

List of works by Emmanuelle Charpentier

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

A Two-Component Regulatory System Impacts Extracellular Membrane-Derived Vesicle Production in Group A Streptococcus

A crucial role for Lyn in TIMP-1 erythroid cell survival signalling pathway

A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum

Adaptation in CRISPR-Cas Systems

Adopt a moratorium on heritable genome editing

Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes

An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3'-to-5' exoRNases and RNase Y

An outbreak of rubella in the Federation of Bosnia and Herzegovina between December 2009 and May 2010 indicates failure to vaccinate during wartime (1992–1995) ⬇️

An overview of RNAs with regulatory functions in gram-positive bacteria

An updated evolutionary classification of CRISPR-Cas systems

Antibiotic resistance in Listeria spp.

Bacterial flagella grow through an injection-diffusion mechanism

Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity

Biotechnology: Rewriting a genome

Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

CRISPR germline engineering--the community speaks

CRISPR-Cas in Streptococcus pyogenes

CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo

CRISPR-Cas9: how research on a bacterial RNA-guided mechanism opened new perspectives in biotechnology and biomedicine

CRISPR-Cas: biology, mechanisms and relevance

CRISPR-Cas: more than ten years and still full of mysteries

Candida bloodstream infection in patients with systemic autoimmune diseases

Catalytically Active Cas9 Mediates Transcriptional Interference to Facilitate Bacterial Virulence

Characterization of a new class of tetracycline-resistance gene tet(S) in Listeria monocytogenes BM4210.

Characterization of a transcriptional TPP riboswitch in the human pathogen Neisseria meningitidis

Classification and evolution of type II CRISPR-Cas systems

Comparative impact of standard approach, FDG PET and FDG dual-head coincidence gamma camera imaging in preoperative staging of patients with non-small-cell lung cancer

Conjugative Mobilization of the Rolling-Circle Plasmid pIP823 from Listeria monocytogenes BM4293 among Gram-Positive and Gram-Negative Bacteria.

Conjugative mobilization of the rolling-circle plasmid pIP823 from Listeria monocytogenes BM4293 among gram-positive and gram-negative bacteria

Control of laser treatment of 58 cervical condylomas: cyto-colposcopic correlations at 3, 6 and 12 months

Control of membrane barrier during bacterial type-III protein secretion

DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes

Detection of a new subgenotype of hepatitis B virus genotype A in Cameroon but not in neighbouring Nigeria

Distinct Polysaccharide Utilization Determines Interspecies Competition between Intestinal Prevotella spp

Dynamin inhibition interferes with inflammasome activation and cytokine gene expression in Streptococcus pyogenes-infected human macrophages

Editorial overview: Novel technologies in microbiology: Recent advances in techniques in microbiology

Editorial: RNA in bacteria: biogenesis, regulatory mechanisms and functions

Emergence of the trimethoprim resistance gene dfrD in Listeria monocytogenes BM4293.

Emergence of vancomycin tolerance in Streptococcus pneumoniae

Engineering of temperature- and light-switchable Cas9 variants

Ethoxyfagaronine, a synthetic analogue of fagaronine that inhibits vascular endothelial growth factor-1, as a new anti-angiogeneic agent.

Evolution and classification of the CRISPR-Cas systems

Evolution of polyvalent intravenous immunoglobulins (IVIg) prescription, at the Assistance Publique - Hopitaux de Paris between 1988 and 1997. Results of the plan of action set up in order to regulate the prescription

Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants

Extracellular Vesicle RNA: A Universal Mediator of Microbial Communication?

Extracellular targeting of choline-binding proteins in Streptococcus pneumoniae by a zinc metalloprotease

Finding Her Niche: An Interview with Emmanuelle Charpentier

Functional Diversity of AAA+ Protease Complexes in Bacillus subtilis

Functional analysis of the group A streptococcal luxS/AI-2 system in metabolism, adaptation to stress and interaction with host cells

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

Group A streptococcus activates type I interferon production and MyD88-dependent signaling without involvement of TLR2, TLR4, and TLR9.

Harnessing CRISPR-Cas9 immunity for genetic engineering

Hypothesis: RNA and DNA Viral Sequence Integration into the Mammalian Host Genome Supports Long-Term B Cell and T Cell Adaptive Immunity

Identification of a Streptococcus pneumoniae gene locus encoding proteins of an ABC phosphate transporter and a two-component regulatory system

Identification of endoribonuclease specific cleavage positions reveals novel targets of RNase III in Streptococcus pyogenes

Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase

In vivo 3'-to-5' exoribonuclease targetomes of

Incidence of antibiotic resistance in Listeria species.

Insertion sequence 1515 in the ply gene of a type 1 clinical isolate of Streptococcus pneumoniae abolishes pneumolysin expression

Low-density lipoprotein receptor-related protein-1 mediates endocytic clearance of tissue inhibitor of metalloproteinases-1 and promotes its cytokine-like activities

Lysogenic transfer of group A Streptococcus superantigen gene among Streptococci

Management of cranial-injured patients in the era of the Emergency Medical Service and the scanner. Comparative epidemiologic study with a 12-year interval in the same department of neurosurgery, in the Paris region

McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR

Mechanisms of antibiotic resistance and tolerance in Streptococcus pneumoniae

Memory of viral infections by CRISPR-Cas adaptive immune systems: acquisition of new information

Multicentre study to determine the Etest epidemiological cut-off values of antifungal drugs in Candida spp. and Aspergillus fumigatus species complex

Novel cassette-based shuttle vector system for gram-positive bacteria

Penicillin tolerance genes ofStreptococcus pneumoniae: the ABC‐type manganese permease complex Psa ⬇️

Performance evaluation of different strategies based on microscopy techniques, rapid diagnostic test and molecular loop-mediated isothermal amplification assay for the diagnosis of imported malaria

Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems

Plakoglobin suppresses epithelial proliferation and hair growth in vivo

Presence of the Listeria tetracycline resistance gene tet(S) in Enterococcus faecalis

RNA sequencing uncovers antisense RNAs and novel small RNAs in Streptococcus pyogenes

RNA techniques for bacteria

RNase Y-mediated regulation of the streptococcal pyrogenic exotoxin B

Refined sgRNA efficacy prediction improves large- and small-scale CRISPR-Cas9 applications

Regulation of growth inhibition at high temperature, autolysis, transformation and adherence in Streptococcus pneumoniae by clpC.