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List of works by Ryūichi Morishita

A Novel Therapeutic Peptide as a Partial Agonist of RANKL in Ischemic Stroke

scientific article

A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction

scientific article published on 07 March 2017

AJP001, a novel helper T-cell epitope, induces a humoral immune response with activation of innate immunity when included in a peptide vaccine

scientific article published on 22 November 2019

Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy

scientific article (publication date: April 2006)

An efficient gene transfer method mediated by ultrasound and microbubbles into the kidney

scientific article

Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy.

scientific article

Angiotensin II Peptide Vaccine Protects Ischemic Brain Through Reducing Oxidative Stress

scientific article published on 31 March 2017

Cilnidipine, but not amlodipine, ameliorates osteoporosis in ovariectomized hypertensive rats through inhibition of the N-type calcium channel

scientific article published in September 2011

Cross-talk of receptor activator of nuclear factor-κB ligand signaling with renin-angiotensin system in vascular calcification

scientific article published on 11 April 2013

Current therapies and investigational drugs for peripheral arterial disease

scientific article

Decrease in blood pressure and regression of cardiovascular complications by angiotensin II vaccine in mice

scientific article published on 27 March 2013

Development of a novel antimicrobial peptide, AG-30, with angiogenic properties

scientific article

Development of an IL-17A DNA Vaccine to Treat Systemic Lupus Erythematosus in Mice

scientific article published on 12 February 2020

Development of high-throughput functional screening of therapeutic genes, using a hemagglutinating virus of Japan envelope vector

scientific article published in April 2006

Development of novel DNA vaccine for VEGF in murine cancer model

scientific article

Development of novel decoy oligonucleotides: advantages of circular dumb-bell decoy.

scientific article

Development of nucleic acid drugs for neurological disorders

scientific article published on January 2012

Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes

scientific article

Differential regulation of amyloid precursor protein/presenilin 1 interaction during Aβ40/42 [corrected] production detected using fusion constructs

scientific article

Differential response of vascular hepatocyte growth factor concentration and lipid accumulation between telmisartan and losartan in ApoE-deficient mice

scientific article published on September 2008

Dipeptidyl peptidase-4 inhibitor improves neovascularization by increasing circulating endothelial progenitor cells

scientific article

Do angiotensin receptor blockers protect against Alzheimer's disease?

scientific article published on June 2013

Effective transfection of a cis element "decoy" of the nuclear factor-kappaB binding site into the experimental choroidal neovascularization

scientific article

Estrogen attenuates vascular remodeling in Lp(a) transgenic mice

scientific article published on 25 January 2010

Estrogen inhibits vascular calcification via vascular RANKL system: common mechanism of osteoporosis and vascular calcification

scientific article published in July 2010

Evaluating the potential of the GFAP-KLH immune-tolerizing vaccine for type 1 diabetes in mice

scientific article published on 7 December 2016

Experimental and Clinical Application of Plasmid DNA in the Field of Central Nervous Diseases ⬇️

scientific article published on December 1, 2011

FHL-2 suppresses VEGF-induced phosphatidylinositol 3-kinase/Akt activation via interaction with sphingosine kinase-1.

scientific article

Gene Therapy with Transcription Factor Decoy Oligonucleotides as a Potential Treatment for Cardiovascular Diseases ⬇️

scientific article published on May 1, 2003

Gene therapy and cell-based therapies for therapeutic angiogenesis in peripheral artery disease

scientific article

Gene transfer of hepatocyte growth factor to subarachnoid space in cerebral hypoperfusion model.

scientific article

Glial fibrillary acidic protein (GFAP) is a novel biomarker for the prediction of autoimmune diabetes

scientific article published on 25 May 2017

HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function

scientific article

HMG-Co A reductase inhibitors in the treatment of cardiovascular diseases: stabilization of coronary artery plaque

scientific article

HVJ-based non-viral gene transfer method: successful gene therapy using HGF and VEGF genes in experimental ischemia

scientific article

Hepatocyte Growth Factor Prevented High-Fat Diet-Induced Obesity and Improved Insulin Resistance in Mice.

scientific article

Hepatocyte growth factor as cardiovascular hormone: role of HGF in the pathogenesis of cardiovascular disease

scientific article

Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.

scientific article

In vivo evidence of angiogenesis induced by transcription factor Ets-1: Ets-1 is located upstream of angiogenesis cascade.

scientific article

Increase in peripheral blood flow by intravenous administration of prostaglandin E1 in patients with peripheral arterial disease, accompanied by up-regulation of hepatocyte growth factor

scientific article published in February 2004

Inhibition of neointima formation through DNA vaccination for apolipoprotein(a): a new therapeutic strategy for lipoprotein(a)

scientific article published on January 2013

Irbesartan improves endothelial dysfunction, abnormal lipid profile, proteinuria and liver dysfunction in Zucker diabetic fatty rats independent of glucose and insulin levels ⬇️

scientific article published on June 30, 2011

Links Between Hypertension and Osteoporosis: Benidipine Ameliorates Osteoporosis in Ovariectomized Hypertensive Rats Through Promotion of Osteoblast Proliferation and Inhibition of Osteoclast Differentiation

Long-Term Reduction of High Blood Pressure by Angiotensin II DNA Vaccine in Spontaneously Hypertensive Rats

scientific article published on 26 May 2015

Long-term expression of periostin during the chronic stage of ischemic stroke in mice

scientific article published on 20 March 2014

Modeling transient retinal ischemia in mouse by ligation of pterygopalatine artery

scientific article published on October 2015

Molecular therapy via transcriptional regulation with double-stranded oligodeoxynucleotides as decoys

scientific article

Nifedipine prevents hepatic fibrosis in a non-alcoholic steatohepatitis model induced by an L-methionine-and choline-deficient diet ⬇️

scientific article published on September 21, 2011

Nonviral gene transfer of human hepatocyte growth factor improves streptozotocin-induced diabetic neuropathy in rats

scientific article

Nonviral retrograde gene transfer of human hepatocyte growth factor improves neuropathic pain-related phenomena in rats

scientific article

Novel anti-microbial peptide SR-0379 accelerates wound healing via the PI3 kinase/Akt/mTOR pathway

scientific article

Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells

scientific article published on 13 October 2005

OPG/RANKL/RANK axis is a critical inflammatory signaling system in ischemic brain in mice

scientific article

Oligonucleotide-Based Molecular Therapy for Restenosis after Angioplasty ⬇️

scientific article published on November 1, 2003

Oral nuclear factor-κB decoy oligonucleotides delivery system with chitosan modified poly(d,l-lactide-co-glycolide) nanospheres for inflammatory bowel disease ⬇️

scientific article published on January 1, 2011

Peptide Vaccines for Hypertension and Diabetes Mellitus

scientific article

Periostin as a novel factor responsible for ventricular dilation

scientific journal article

Possible modification of Alzheimer's disease by statins in midlife: interactions with genetic and non-genetic risk factors

scientific article

Potential role of CYLD (Cylindromatosis) as a deubiquitinating enzyme in vascular cells

scientific article

Potential therapeutic applications of decoy oligonucleotides.

scientific article

Prevention and regression of non-alcoholic steatohepatitis (NASH) in a rat model by metabosartan, telmisartan ⬇️

scientific article published on October 1, 2010

Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study

scientific article

Recent progress in cerebrovascular gene therapy

scientific article

Recent progress in gene therapy for cardiovascular disease

scientific article

Reduction of brain beta-amyloid (Abeta) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, through increase in degradation of amyloid precursor protein C-terminal fragments (APP-CTFs) and Abeta clearance

scientific article

Results of a double-blind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia

scientific article

Roles of vascular and metabolic components in cognitive dysfunction of Alzheimer disease: short- and long-term modification by non-genetic risk factors

scientific article

Systemic administration of ribbon-type decoy oligodeoxynucleotide against nuclear factor κB and ets prevents abdominal aortic aneurysm in rat model

scientific article published on 28 September 2010

Tea polyphenols regulate key mediators on inflammatory cardiovascular diseases

scientific article

The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice

scientific article published on 18 May 2020

The dipeptidyl peptidase-4 inhibitor teneligliptin improved endothelial dysfunction and insulin resistance in the SHR/NDmcr-cp rat model of metabolic syndrome

scientific article published on 13 March 2014

The roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer disease

scientific article

Therapeutic Effects of Systemic Administration of the Novel RANKL-Modified Peptide, MHP1, for Ischemic Stroke in Mice

scientific article published on 30 July 2018

Therapeutic Vaccine Against S100A9 (S100 Calcium-Binding Protein A9) Inhibits Thrombosis Without Increasing the Risk of Bleeding in Ischemic Stroke in Mice

scientific article published on 01 December 2018

Therapeutic vaccine against DPP4 improves glucose metabolism in mice

scientific article published on 17 March 2014

Therapeutic vaccines for hypertension and dyslipidemia

scientific article

Transcription Factors as Molecular Targets: Molecular Mechanisms of Decoy ODN and their Design ⬇️

scientific article published on November 1, 2003

Transcription factor as molecular targets: is transcription factor decoy a novel drug?

scientific article published on November 2003

Transplantation of lineage-negative stem cells in pterygopalatine artery ligation induced retinal ischemia-reperfusion injury in mice

scientific article

Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappaB activation.

scientific article

Unique remodeling processes after vascular injury in intracranial arteries: analysis using a novel mouse model

scientific article

Variation in OSBPL10 is associated with dyslipidemia

scientific article published on 12 March 2010

Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis

scientific article

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