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List of works by Kimiko Murofushi

(S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity

scientific article

2-Carba cyclic phosphatidic acid inhibits lipopolysaccharide-induced prostaglandin E2 production in a human macrophage cell line

scientific article published on 19 July 2019

2-Carba-lysophosphatidic acid is a novel β-lysophosphatidic acid analogue with high potential for lysophosphatidic acid receptor activation and autotaxin inhibition

scientific article published on 30 August 2021

2-O-Carba-oleoyl cyclic phosphatidic acid induces glial proliferation through the activation of lysophosphatidic acid receptor

scientific article published on 23 December 2017

2-carba cyclic phosphatidic acid suppresses inflammation via regulation of microglial polarisation in the stab-wounded mouse cerebral cortex.

scientific article

A Trisialosyl Ganglioside GT3 of Hog Kidney. Structure and Biosynthesis In Vitro1 ⬇️

scientific article published on 01 December 1981

A new radiochemical assay for argininosuccinase with purified [14C]argininosuccinate

scientific article published on 01 July 1980

A novel intracellular acid proteinase from the plasmodia of a true slime mold, Physarum polycephalum

scientific article published on 01 January 1995

A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae

scientific article

A novel pyrazolone, 4,4-dichloro-1-(2,4-dichlorophenyl)-3-methyl-5-pyrazolone, as a potent catalytic inhibitor of human telomerase

scientific article published on August 2004

A novel trisialosyl ganglioside, IV3 alpha (NeuAc)3nLcOse4Cer, from hog kidney cortex

scientific article published on 01 February 1983

Activation of a Ca(2+)-dependent protein kinase in response in heat shock in the myxoamoebae of a true slime mold, Physarum polycephalum

scientific article published on 01 December 1996

Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts

scientific article

Antinociceptive effect of cyclic phosphatidic acid and its derivative on animal models of acute and chronic pain

scientific article

Argininosuccinase from bovine brain: Isolation and comparison of catalytic, physical, and chemical properties with the enzymes from liver and kidney ⬇️

scientific article published on 01 May 1979

Attenuation by cyclic phosphatidic acid of peritoneal metastasis of azoxymethane-induced intestinal cancers in Wistar rats.

scientific article published in June 2004

Biological functions of a novel lipid mediator, cyclic phosphatidic acid

scientific article

Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis

scientific article

Changes in phospholipid composition and phospholipase D activity during the differentiation of Physarum polycephalum

scientific article published on 01 April 1990

Chinese hamster ovary cells expressing a novel type of acetylated low density lipoprotein receptor. Isolation and characterization

scientific article published on 01 January 1995

Cholesterol glucosylation is catalyzed by transglucosylation reaction of β-glucosidase 1.

scientific article published on 6 November 2013

Cholesteryl glucoside-induced protection against gastric ulcer

scientific article published in June 2003

Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis

scientific article published on February 2012

Correction to: Protective and therapeutic role of 2-carbacyclic phosphatidic acid in demyelinating disease.

scientific article

Corrigendum to "Quantitative determination of cyclic phosphatidic acid and its carba analog in mouse organs and plasma using LC-MS/MS" [J. Chromatogr. B 1076 (2018) 15-21].

scientific article published on 16 March 2018

Cyclic phosphatidic acid and lysophosphatidic acid induce hyaluronic acid synthesis via CREB transcription factor regulation in human skin fibroblasts

scientific article

Cyclic phosphatidic acid decreases proliferation and survival of colon cancer cells by inhibiting peroxisome proliferator-activated receptor γ.

scientific article published on 13 October 2010

Cyclic phosphatidic acid elicits neurotrophin‐like actions in embryonic hippocampal neurons ⬇️

scientific article published on December 1, 2003

Cyclic phosphatidic acid influences the expression and regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 cells

scientific article published on 21 November 2010

Cyclic phosphatidic acid inhibits RhoA-mediated autophosphorylation of FAK at Tyr-397 and subsequent tumor-cell invasion

scientific article published on June 1, 2003

Cyclic phosphatidic acid inhibits the secretion of vascular endothelial growth factor from diabetic human coronary artery endothelial cells through peroxisome proliferator-activated receptor gamma

scientific article published on 22 May 2015

Cyclic phosphatidic acid is produced by autotaxin in blood

scientific article published on 12 July 2006

Cyclic phosphatidic acid relieves osteoarthritis symptoms

scientific article

Cyclic phosphatidic acid stimulates respiration without producing vasopressor or tachycardiac effects in rats

scientific article published on 20 May 2006

Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction in mice

scientific article published on 30 July 2014

DNA packaging proteins Glom and Glom2 coordinately organize the mitochondrial nucleoid of Physarum polycephalum

scientific article published on 23 March 2011

DNA synthesis by the isolated nuclear matrix from synchronized plasmodia of Physarum polycephalum

scientific article published on 01 April 1989

DNA synthesis in isolated nuclei from synchronized plasmodia of Physarum polycephalum

scientific article published on 01 June 1987

Determinants of receptor subtype specificity in the LPA-like lipid mediator family.

scientific article published on January 1999

Dimerization and the signal transduction pathway of a small in-frame deletion in the epidermal growth factor receptor

scientific article published on 22 December 2005

Distinct roles of two separablein vitroactivities of yeast Mre11 in mitotic and meiotic recombination ⬇️

scientific article published on November 2, 1998

Early weaning induces anxiety and precocious myelination in the anterior part of the basolateral amygdala of male Balb/c mice

scientific article published on 22 August 2008

Effect of Endurance Exercise Training on Oxidative Stress in Spontaneously Hypertensive Rats (SHR) After Emergence of Hypertension ⬇️

scientific article published on September 9, 2010

Effects of cyclic phosphatidic acid on delayed neuronal death following transient ischemia in rat hippocampal CA1.

scientific article published on 22 September 2010

Efficient synthesis of 3-O-thia-cPA and preliminary analysis of its biological activity toward autotaxin

scientific article published on 27 May 2011

Evaluation of the pharmacokinetics of 2-carba-cyclic phosphatidic acid by liquid chromatography-triple quadrupole mass spectrometry

scientific article published on 13 April 2020

Existence of a bioactive lipid, cyclic phosphatidic acid, bound to human serum albumin

scientific article published on 01 January 1999

Expression of UDP-glucose: poriferasterol glucosyltransferase in the process of differentiation of a true slime mold, Physarum polycephalum

scientific article

Expression of a 66-kD heat shock protein associated with the process of cyst formation of a true slime mold, Physarum polycephalum

scientific article published on 01 October 1992

Expression of cholesteryl glucoside by heat shock in human fibroblasts

scientific article

Expression of poriferasterol monoglucoside associated with differentiation of Physarum polycephalum

scientific article published on 01 December 1987

Glom is a novel mitochondrial DNA packaging protein in Physarum polycephalum and causes intense chromatin condensation without suppressing DNA functions.

scientific article published on 5 September 2003

Heat stress induces a glycosylation of membrane sterol in myxoamoebae of a true slime mold, Physarum polycephalum

scientific article published on 01 January 1997

Hyperosmotic stress-induced reorganization of actin bundles in Dictyostelium cells over-expressing cofilin

scientific article published on 01 June 1999

Identification of residues responsible for ligand recognition and regioisomeric selectivity of lysophosphatidic acid receptors expressed in mammalian cells

scientific article published on 22 August 2005

In-frame deletion in the EGF receptor alters kinase inhibition by gefitinib

scientific article published on August 2006

Inhibition of cell proliferation by a unique lysophosphatidic acid, PHYLPA, isolated from Physarum polycephalum: signaling events of antiproliferative action by PHYLPA

scientific article published on 01 October 1993

Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid

scientific article

Inhibition of tumor invasion and metastasis by a novel lysophosphatidic acid (cyclic LPA)

scientific article published on 01 June 1999

Ionizing radiation, inflammation, and their interactions in colon carcinogenesis in Mlh1-deficient mice

scientific article

Isolation of argininosuccinase from bovine brain: catalytic, physical and chemical properties compared to liver and kidney enzymes

scientific article published in January 1982

LPA5 signaling is involved in multiple sclerosis-mediated neuropathic pain in the cuprizone mouse model.

scientific article published on 2 February 2018

Lysophosphatidic acid-activated Cl- current activity in human systemic sclerosis skin fibroblasts

scientific article

MOV10 as a novel telomerase-associated protein

scientific article

Microtubule-associated protein-2 stimulates DNA synthesis catalyzed by the nuclear matrix

scientific article published on 01 March 1989

Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid

scientific article

Naturally occurring analogs of lysophosphatidic acid elicit different cellular responses through selective activation of multiple receptor subtypes.

scientific article published on December 1998

Novel sterol glucosyltransferase in the animal tissue and cultured cells: evidence that glucosylceramide as glucose donor

scientific article published on 17 March 2011

Oleic acid is a potent inducer for lipid droplet accumulation through its esterification to glycerol by diacylglycerol acyltransferase in primary cortical astrocytes

scientific article published on 25 September 2019

Pertuzumab, a novel HER dimerization inhibitor, inhibits the growth of human lung cancer cells mediated by the HER3 signaling pathway

scientific article

Pharmacological evaluation of a novel cyclic phosphatidic acid derivative 3-S-cyclic phosphatidic acid (3-S-cPA).

scientific article published on 3 April 2012

Phospholipase D2-dependent inhibition of the nuclear hormone receptor PPARgamma by cyclic phosphatidic acid

scientific article

Protection of Neuroblastoma Neuro2A Cells from Hypoxia-Induced Apoptosis by Cyclic Phosphatidic Acid (cPA) ⬇️

scientific article published on December 12, 2012

Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in demyelinating disease

scientific article

Qualitative and quantitative comparison of cyclic phosphatidic acid and its related lipid species in rat serum using hydrophilic interaction liquid chromatography with tandem-mass spectrometry

scientific article published on 04 July 2018

Quantitative determination of cyclic phosphatidic acid and its carba analog in mouse organs and plasma using LC-MS/MS.

scientific article published on 8 January 2018

Regulation of levels of actin threonine phosphorylation during life cycle of Physarum polycephalum

scientific article published on February 2006

Release of cyclic phosphatidic acid from gelatin-based hydrogels inhibit colon cancer cell growth and migration.

scientific article

STAT3 and PKC differentially regulate telomerase activity during megakaryocytic differentiation of K562 cells

scientific article published on 18 April 2007

Saturated fatty acid is a principal cause of anxiety-like behavior in diet-induced obese rats in relation to serum lysophosphatidyl choline level

scientific article published on 21 October 2019

Selective inhibition of DNA polymerase alpha by a polysaccharide purified from slime of Physarum polycephalum

scientific article published on 01 July 1987

Selective inhibition of DNA polymerase-α family with chemically synthesized derivatives of PHYLPA, a unique Physarum lysophosphatidic acid ⬇️

scientific article published on August 24, 1995

Side-chain structure is critical for the transport of sterols from lysosomes to cytoplasm

scientific article published on 01 June 1995

Steryl glucoside is a lipid mediator in stress-responsive signal transduction

scientific article published on June 2002

Stimulation of sea urchin DNA polymerase by protein factors. II. Formation of active complex in DNA polymerase reaction

scientific article published on March 18, 1977

Structural and enzymatic characterization of physarolisin (formerly physaropepsin) proves that it is a unique serine-carboxyl proteinase

scientific article

Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid ⬇️

scientific article published on October 8, 2010

Synthesis of enantiopure 2-carba-cyclic phosphatidic acid and effects of its chirality on biological functions ⬇️

scientific article published on January 28, 2011

The Plasmodium HU homolog, which binds the plastid DNA sequence-independent manner, is essential for the parasite's survival

scientific article published on 7 April 2009

The effect of cyclic phosphatidic acid on the proliferation and differentiation of mouse cerebellar granule precursor cells during cerebellar development

scientific article

The macroscopic structure of RADA16 peptide hydrogel stimulates monocyte/macrophage differentiation in HL60 cells via cholesterol synthesis ⬇️

scientific article published on March 19, 2013

Unique characteristics of radiation-induced apoptosis in the postnatally developing small intestine and colon of mice.

scientific article

Visualization of Mitochondrial and Apicoplast Nucleoids in the Human Malaria Parasite Plasmodium falciparum by SYBR Green I and PicoGreen Staining

scholarly article by Katsura Maeda-Sano et al published 2009 in Cytologia

Xenopus oocytes express multiple receptors for LPA-like lipid mediators

scientific article published in March 1996

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