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List of works by Marcel R.M. van den Brink

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A DKMS (German Bone Marrow Donor Center) view on cryopreservation of unrelated donor stem cell products during the COVID-19 pandemic

scientific article published on 24 December 2020

A Phase I Dose Escalation Trial of Donor T Cells Sensitized with Pentadecapeptides of the CMV-pp65 Protein for the Treatment of CMV Infections Following Allogeneic Hematopoietic Stem Cell Transplants. ⬇️

scholarly article

A compilation of fecal microbiome shotgun metagenomics from hematopoietic cell transplantation patients

publication published on 18 May 2022

A phase II pilot trial of concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin 2, and interferon alpha-2B in patients with metastatic melanoma.

scientific article published in June 2000

A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activity

scientific article

A tribute to E. Donnall Thomas

scientific article published on 2 January 2013

ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells

scientific article published on 25 December 2018

Ablation of B7-H3 but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer

scientific article published on 29 June 2015

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL ⬇️

scientific article

Absence of Inducible Costimulator (ICOS) on Alloreactive T Cells Reduces Graft-versus-Host-Disease While Leaving Graft-Versus-Tumor Activity Intact. ⬇️

scholarly article

Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease

scientific article published on 09 July 2010

Absence of beta7 integrin results in less graft-versus-host disease because of decreased homing of alloreactive T cells to intestine

scientific article published on 15 November 2005

Absence of donor T-cell-derived soluble TNF decreases graft-versus-host disease without impairing graft-versus-tumor activity

scientific article published on 29 March 2007

Absence of inducible costimulator on alloreactive T cells reduces graft versus host disease and induces Th2 deviation

scientific article published on 14 June 2005

Adoptive Immunotherapy with Donor T Cells Sensitized with Overlapping Pentadecapeptides of the CMV-pp65 Protein for the Treatment of Persistent CMV Antigenemia Following Allogeneic Hematopoietic Stem Cell Transplants ⬇️

scholarly article

Adoptive precursor cell therapy to enhance immune reconstitution after hematopoietic stem cell transplantation in mouse and man.

scientific article published on 15 November 2008

Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation

scientific article

Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity

scientific article published on 15 May 2013

Age-Associated Changes in the Differentiation Potentials of Human Circulating Hematopoietic Progenitors to T- or NK-Lineage Cells ⬇️

scientific article published on May 13, 2013

Age-Related Thymic Involution Triggers Intrinsic Regeneration Pathways but They Remain Ineffective for Its Renewal ⬇️

scholarly article

Allogeneic haematopoietic stem cell transplantation: individualized stem cell and immune therapy of cancer

scientific article

Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease

scientific article published in 2022

Antibiotic-Induced Shifts in Fecal Microbiota Density and Composition during Hematopoietic Stem Cell Transplantation

scientific article published on 21 August 2019

Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells

scientific article

Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium.

scientific article published on 31 October 2017

Availability of cord blood extends allogeneic hematopoietic stem cell transplant access to racial and ethnic minorities

scientific article published on 25 August 2010

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

scientific article published on 26 March 2015

Behavioural traits propagate across generations via segregated iterative-somatic and gametic epigenetic mechanisms

scientific article

Blood stem cell transplantation in older patients

scientific article published in December 2009

CCR2 is required for CD8-induced graft-versus-host disease.

scientific article published on 21 July 2005

CD19-Targeted Donor T Cells Exert Potent Graft Versus Lymphoma Activity and Attenuated Gvhd ⬇️

scholarly article

Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation

scientific article

Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB-Controlled Oxidative Stress Responses

scientific article

Chronic Lymphocytic Leukemia (CLL) Signaling Profiling Identifies CLL-Specific Signaling Impairment That Discriminates CLL B-Cells From Normal Circulating B Cells ⬇️

scholarly article

Circulating Hematopoietic Stem and Progenitor Cells in Aging Atomic Bomb Survivors

scientific article published on 31 December 2015

Clinical Relevant Alterations Identified By Comprehensive Genomic Profiling Can Potentially Improve Therapeutic Option and Change Prognosis in Hematologic Malignancies ⬇️

scholarly article

Clinical applications of palifermin: amelioration of oral mucositis and other potential indications

scientific article

Clinical strategies to enhance T cell reconstitution

scientific article published on 26 October 2007

Clinical strategies to enhance posttransplant immune reconstitution

scientific article published on January 2008

Clinical strategies to enhance thymic recovery after allogeneic hematopoietic stem cell transplantation.

scientific article published on September 2013

Compilation of longitudinal microbiota data and hospitalome from hematopoietic cell transplantation patients

publication published on 02 March 2021

Compositional flux within the intestinal microbiota and risk for bloodstream infection with gram-negative bacteria

scientific article published on 24 January 2020

Comprehensive Mutational Profiling In Myelodysplastic Syndromes Treated With Decitabine and Tretinoin ⬇️

scholarly article

Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo

scientific article

Constitutive Activation of the B Cell Receptor Underlies Dysfunctional Signaling in Chronic Lymphocytic Leukemia

scientific article published on 01 July 2019

Corrigendum to "Relationship between spontaneous γH2AX foci formation and progenitor functions in circulating hematopoietic stem and progenitor cells among atomic-bomb survivors" [Mutat. Res. - Genet. Toxicol. Environ. Mutagen. 802 (2016) 59-65].

scientific article published on 10 November 2017

Corrigendum: Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease

scientific article published on 01 September 2016

Corrigendum: Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury

scientific article published on 01 April 2018

Cross-species bone marrow transplantation: evidence for tolerance induction, stem cell engraftment, and maturation of T lymphocytes in a xenogeneic stromal environment (rat----mouse) ⬇️

scientific article published on August 1, 1991

Cryopreservation for all is no option in unrelated stem cell transplantation (Comment to: Dholaria B, et al. Securing the graft during pandemic: are we ready for cryopreservation for all? Biol Blood Marrow Transplant. 2020;26(7):e145-e146.).

scientific article published on 18 August 2020

Cytolytic pathways in haematopoietic stem-cell transplantation

scientific article

DNA immunization against tissue-restricted antigens enhances tumor immunity after allogeneic hemopoietic stem cell transplantation.

scientific article published on September 2006

Day 45 Lymphocyte Recovery Is Independently Associated with Transplant-Related Mortality after Adult Myeloablative Double-Unit Cord Blood Transplantation (dCBT) ⬇️

scholarly article

Direct evidence for new T-cell generation by patients after either T-cell-depleted or unmodified allogeneic hematopoietic stem cell transplantations

scientific article published on 01 September 2002

Diversification and Evolution of Vancomycin-Resistant Enterococcus faecium during Intestinal Domination

scientific article published on 20 June 2019

Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity.

scientific article published on 9 January 2017

Donor T cell-derived TNF is required for graft-versus-host disease and graft-versus-tumor activity after bone marrow transplantation

scientific article published on 07 November 2002

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

scientific article published on 03 October 2019

Double-Unit Cord Blood (CB) Transplantation with Haplo-Identical CD34+ Cells (haplo-dCBT) May Speed Neutrophil Recovery Although Successful Bridging Is Contingent on Close Haplo-Winning CB Unit HLA-Match ⬇️

scholarly article

Early Clostridium difficile infection during allogeneic hematopoietic stem cell transplantation.

scientific article

Early Immune Recovery Predicts Overall and Disease-Free Survival After Allogeneic Hematopoietic Stem Cell Transplantation. ⬇️

scholarly article

Early recovery of T-cell function predicts improved survival after T-cell depleted allogeneic transplant

scientific article published on 10 January 2017

Effects of in vivo treatment with FK506 on natural killer cells in rats

scientific article

Empiric antibiotic use in allogeneic hematopoietic cell transplantation: should we avoid anaerobe coverage?

scientific article published on 17 November 2017

Endothelial Cells Promote Endogenous Thymic Regeneration after Injury Via BMP4 Signaling ⬇️

scholarly article

Enhanced Immune Reconstitution by Sex Steroid Ablation following Allogeneic Hemopoietic Stem Cell Transplantation

scientific article published on 18 May 2007

Enhanced hematopoietic stem cell function mediates immune regeneration following sex steroid blockade

scientific article

Enhanced responses to tumor immunization following total body irradiation are time-dependent

scientific article

Enhancing T cell reconstitution after hematopoietic stem cell transplantation: a brief update of the latest trends

scientific article published on October 2007

Eomesodermin Regulates The Early Activation Of Alloreactive CD4 T Cells and Is Critical For Both Gvh and GVL Responses ⬇️

scholarly article

Ex Vivo CD34+-Selected T Cell-Depleted Peripheral Blood Stem Cell Grafts for Allogeneic Hematopoietic Stem Cell Transplantation in Acute Leukemia and Myelodysplastic Syndrome Is Associated with Low Incidence of Acute and Chronic Graft-versus-Host Di

scientific article published on 22 December 2016

Expression of the Butyrate/Niacin Receptor, GPR109a on T Cells Plays an Important Role in a Mouse Model of Graft Versus Host Disease ⬇️

scholarly article

Extrathymic development of murine T cells after bone marrow transplantation

scientific article

Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors.

scientific article published on 11 September 2017

Fecal microbiota diversity disruption and clinical outcomes after auto-HCT: a multicenter observational study

scientific article published on 01 March 2021

Fludarabine-based conditioning secures engraftment of second hematopoietic stem cell allografts (HSCT) in the treatment of initial graft failure

scientific article published on 7 September 2007

Free-hand ultrasound guidance permits safe and efficient minimally invasive intrathymic injections in both young and aged mice

scientific article

GITR activation induces an opposite effect on alloreactive CD4(+) and CD8(+) T cells in graft-versus-host disease

scientific article

Generation of natural killer cells from Thy 1.1+ bone marrow precursor cells in the rat ⬇️

scientific article published on 01 November 1991

Genetic Engineering of Donor T Cells for BMT Immunotherapy: Expression of TRAIL and PLZF Selectively Enhances GVT and Abrogates Gvhd ⬇️

scholarly article

Genetically engineered donor T cells to optimize graft-versus-tumor effects across MHC barriers

scientific article published on January 2014

Genetics of Intestinal Graft-Versus-Host Disease ⬇️

scholarly article

Genome-Wide Screening for Enteric Colonization Factors in Carbapenem-Resistant ST258 Klebsiella pneumoniae

scientific article published in 2019

Genomic Analysis of Serial Samples from CLL Patients Identifies Clonal Events Associated with Disease Progression ⬇️

scholarly article

Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms.

scientific article

Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity.

scientific article published on June 2006

Graft-versus-host disease: regulation by microbe-associated molecules and innate immune receptors

scientific article published on 30 December 2009

Greater than the sum of their parts: combination strategies for immune regeneration following allogeneic hematopoietic stem cell transplantation

scientific article published on 29 June 2011

Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy

scientific article published in 2022

Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease

scientific article

Gut microbiota derived propionate regulates the expression of Reg3 mucosal lectins and ameliorates experimental colitis in mice

scientific article published on 30 March 2020

Gut microbiota injury in allogeneic haematopoietic stem cell transplantation

scientific article published on 16 February 2018

Haematopoietic cell transplantation outcomes are linked to intestinal mycobiota dynamics and an expansion of Candida parapsilosis complex species

scientific article published on 11 November 2021

Hematopoietic Cell Transplantation Comorbidity Index Predicts Outcomes in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndromes Receiving CD34+ Selected Grafts for Allogeneic Hematopoietic Cell Transplantation.

scientific article

High Day 28 ST2 Biomarker Levels Predict Severe Day 100 Acute Graft-Versus-Host Disease and Day 180 Transplant-Related Mortality After Double-Unit Cord Blood Transplantation ⬇️

scholarly article

High Disease-Free Survival with Enhanced Protection against Relapse after Double-Unit Cord Blood Transplantation When Compared with T Cell-Depleted Unrelated Donor Transplantation in Patients with Acute Leukemia and Chronic Myelogenous Leukemia

scientific article published on 31 July 2015

High day 28 ST2 levels predict for acute graft-versus-host disease and transplant-related mortality after cord blood transplantation

scientific article

High-Depth, Targeted, Next Generation Sequencing Identifies Novel Genetic Alterations in Cutaneous T-Cell Lymphoma ⬇️

scholarly article

High-resolution mycobiota analysis reveals dynamic intestinal translocation preceding invasive candidiasis

scientific article published on 06 January 2020

Highly Selective Irreversible ITK Inhibitor Cpi-818 Reduces Acute Graft-Versus Host Disease

scientific article published in 2021

Histone deacetylation critically determines T cell subset radiosensitivity

scientific article

Host reactive donor T cells are associated with lung injury after experimental allogeneic bone marrow transplantation ⬇️

scientific article published on 01 October 1998

IFN-gamma and Fas ligand are required for graft-versus-tumor activity against renal cell carcinoma in the absence of lethal graft-versus-host disease

scientific article

IL-11 separates graft-versus-leukemia effects from graft-versus-host disease after bone marrow transplantation.

scientific article

IL-17 contributes to CD4-mediated graft-versus-host disease

scientific article published on 17 October 2008

IL-22 Administration Protects Intestinal Stem Cells from Gvhd

IL-22 Is an Intestinal Stem Cell Growth Factor, and IL-22 Administration in Vivo Reduces Morbidity and Mortality in Murine GvHD ⬇️

scholarly article

IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice

scientific article published on 05 February 2021

IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization

scientific article published on 22 August 2016

IL-7 and IL-15: therapeutic cytokines for immunodeficiency

scientific article

IL-7 enhances peripheral T cell reconstitution after allogeneic hematopoietic stem cell transplantation ⬇️

scientific article published on October 1, 2003

Image-guided intrathymic injection of multipotent stem cells supports lifelong T-cell immunity and facilitates targeted immunotherapy

scientific article

Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation: Time To T Up the Thymus

scientific article published on January 2017

Immune Tolerance and Transplantation ⬇️

scientific article published on December 1, 2012

Immune reconstitution following stem cell transplantation

scientific article published on 01 January 2015

Immune recovery after allogeneic hematopoietic stem cell transplantation: is it time to revisit how patients are monitored?

scientific article published on 27 September 2012

Immune-based Therapies for Hematological Malignancies: An Update by the EHA SWG on Immunotherapy of Hematological Malignancies

scientific article published on 29 June 2020

Impact of the Intestinal Microbiota on Infections and Survival Following Hematopoietic Stem Cell Transplantation ⬇️

scholarly article

Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen

scientific article published on 13 July 2020

Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice

scientific article published on May 2016

Increased plasma levels of stromal-derived factor-1 (SDF-1/CXCL12) enhance human thrombopoiesis and mobilize human colony-forming cells (CFC) in NOD/SCID mice

scientific article published in March 2004

Increasing T-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex-mismatched bone marrow transplant model

scientific article

Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification

scientific article published on 18 December 2018

Inhibition of c-Rel Signaling: A Novel Small Molecule-Based Therapy Diminishing T Cell Alloactivation While Preserving Anti-Tumor Activity ⬇️

scholarly article

Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth

scientific article

Insulin-like growth factor-I enhances lymphoid and myeloid reconstitution after allogeneic bone marrow transplantation

scientific article published on 01 June 2003

Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting

scientific article published on 10 March 2016

Intensified Mycophenolate Mofetil Dosing and Higher Mycophenolic Acid Trough Levels Reduce Severe Acute Graft-versus-Host Disease after Double-Unit Cord Blood Transplantation

scientific article published on 14 February 2015

Interleukin-15 enhances immune reconstitution after allogeneic bone marrow transplantation

scientific article published on 27 July 2004

Interleukin-22 drives endogenous thymic regeneration in mice

scientific article

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

scientific article

Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease

scientific article

Interleukin-22: immunobiology and pathology

scientific article published on 11 February 2015

Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease

scientific article published on 11 May 2015

Intestinal Microbiota Composition Prior to CAR T Cell Infusion Correlates with Efficacy and Toxicity ⬇️

scholarly article

Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation.

scientific article

Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation

scientific article

Intestinal microbiota containing Barnesiella species cures vancomycin-resistant Enterococcus faecium colonization.

scientific article published on 14 January 2013

Intrathymic Innate Lymphoid Cells: Long-Lived Mediators Of Immune Regeneration ⬇️

scholarly article

Intrathymic injection of hematopoietic progenitor cells establishes functional T cell development in a mouse model of severe combined immunodeficiency

scientific article

Keratinocyte growth factor (KGF) is required for postnatal thymic regeneration

scientific article published on 22 November 2005

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation.

scientific article

Kinetics of gene expression in murine cutaneous graft-versus-host disease

scientific article

LPAM (α4β7 integrin) is an important homing integrin on alloreactive T cells in the development of intestinal graft-versus-host disease ⬇️

scientific article published on October 16, 2003

Lactose drives Enterococcus expansion to promote graft-versus-host disease

scientific article published on 01 November 2019

Late Effects of Exposure to Ionizing Radiation and Age on Human Thymus Morphology and Function

scientific article

Linkage between dendritic and T cell commitments in human circulating hematopoietic progenitors

scientific article

Long-term survival in patients with peripheral T-cell non-Hodgkin lymphomas after allogeneic hematopoietic stem cell transplant ⬇️

scientific article published on January 31, 2012

Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease.

scientific article

Luteinizing hormone-releasing hormone enhances T cell recovery following allogeneic bone marrow transplantation

scientific article published on May 2009

MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome and correlate with favorable patient outcome after allogeneic HCT

scientific article published in 2022

Maternal Programming of Social Dominance via Milk Cytokines

scientific article published on 10 July 2020

Microbial metabolite sensor GPR43 controls severity of experimental GVHD

scientific article published in Nature Communications

Microbiota Disruption Induced by Early Use of Broad-Spectrum Antibiotics Is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation.

scientific article published on 14 February 2017

Microbiota and Allogeneic Hematopoietic-Cell Transplantation. Reply

scientific article published on 01 June 2020

Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation

scientific article published on 01 February 2020

Microbiota-derived lantibiotic restores resistance against vancomycin-resistant Enterococcus

scientific article published on 21 August 2019

Minimal residual disease negativity in multiple myeloma is associated with intestinal microbiota composition

scientific article published on 01 July 2019

Mixed xenogeneic chimeras (rat + mouse to mouse). Evidence of rat stem cell engraftment, strain-specific transplantation tolerance, and skin-specific antigens

scientific article published on 01 April 1992

Molecular imaging reveals skeletal engraftment sites of transplanted bone marrow cells

scientific article published on 01 January 2006

Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites

scientific article published on 01 October 2020

Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells.

scientific article published on 29 January 2014

Murine Donor 1928z CAR T Cells Exert Potent Graft-Versus-Lymphoma Activity without Graft-Versus-Host-Disease ⬇️

scholarly article

Mutation Profiling of Therapy-Related Myeloid Neoplasms Using Next-Generation Sequencing Demonstrates Distinct Profiles from De Novo Disease ⬇️

scholarly article

Mutational Profiling Of Myeloid Malignancies For Prediction Of Disease Relapse Following Allogeneic Stem Cell Transplantation ⬇️

scholarly article

Mutational correlates of response to hypomethylating agent therapy in acute myeloid leukemia.

scientific article published on 14 July 2016

NCI First International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biology Underlying Recurrence of Malignant Disease following Allogeneic

scientific article published on 10 February 2010

NOD2 regulates hematopoietic cell function during graft-versus-host disease

scientific article published on 08 September 2009

Nature's TRAIL--on a path to cancer immunotherapy

scientific article

Nrf2 regulates CD4 T cell-induced acute graft-versus-host disease in mice

scientific article published on 31 October 2018

Nrf2 regulates haematopoietic stem cell function

scientific article

Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice

scientific article published on 19 March 2018

Organ-derived dendritic cells have differential effects on alloreactive T cells.

scientific article

Overcoming immunological barriers in regenerative medicine

scientific article

P-Selectin in Recipients of Allogeneic Bone Marrow Transplantation Regulates Experimental Graft-Versus-Host-Disease. ⬇️

scholarly article

PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating GVHD

scientific article published on 03 June 2013

Pre-Transplant and Peri-d100 Gastrointestinal Dysbiosis Is Associated with the Subsequent Development of Chronic Graft-Versus-Host Disease ⬇️

scholarly article

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.

scientific article

Preparing for the unthinkable: emergency preparedness for the hematopoietic cell transplant program.

scientific article

Proceedings from the Second Haploidentical Stem Cell Transplantation Symposium-Haplo2014, San Francisco, California, December 4, 2014.

scientific article published on 12 January 2016

Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.

scientific article published in January 2018

Profiling Genomic Alterations Of Diffuse Large B-Cell Lymphoma (DLBCL) At Diagnosis, Relapse, and Transformation, Using a Novel Clinical Diagnostic Targeted Sequencing Platform ⬇️

scholarly article

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

scientific article

Protective Factors in the Intestinal Microbiome Against Clostridium difficile Infection in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation

scientific article

Quantitative assessment of T cell repertoire recovery after hematopoietic stem cell transplantation.

scientific article published on 24 February 2013

Quantitative restoration of immune defense in old animals determined by naive antigen‐specific CD8 T‐cell numbers

scientific article published on 15 March 2022

RAS Pathway Mutations Are Associated with Proliferative Features and Frequently Co-Occur with TET2 mutationsin Philadelphia Negative MPN Subtypes ⬇️

scholarly article

RIG-I activation is critical for responsiveness to checkpoint blockade

scientific article published on 01 September 2019

RIG-I-Induced Type I IFNs Promote Regeneration of the Intestinal Stem Cell Compartment during Acute Tissue Damage ⬇️

scholarly article

RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury

scientific article published on April 2017

Rapidly proliferating CD44hi peripheral T cells undergo apoptosis and delay posttransplantation T-cell reconstitution after allogeneic bone marrow transplantation

scientific article published on 24 September 2008

Recombinant Human Interleukin-7 (CYT107) Enhances CD4 and CD8 T Cell Recovery Following T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplant In Patients with Myeloid Malignancies ⬇️

scholarly article

Recombinant human interleukin-7 (CYT107) promotes T-cell recovery after allogeneic stem cell transplantation ⬇️

scientific article published on September 25, 2012

Reconstitution of the gut microbiota of antibiotic-treated patients by autologous fecal microbiota transplant

scientific article published on 01 September 2018

Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF.

scientific article published on May 2007

Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation

scientific article

Rejuvenation of the aging T cell compartment

scientific article published on 14 July 2009

Relapse after allogeneic hematopoietic cell therapy.

scientific article published on 24 October 2009

Relationship between spontaneous γH2AX foci formation and progenitor functions in circulating hematopoietic stem and progenitor cells among atomic-bomb survivors

scientific article published on 19 April 2016

Remodeling specific immunity by use of MHC tetramers: demonstration in a graft-versus-host disease model

scientific article published on 3 November 2005

Repertoire enhancement with adoptively transferred female lymphocytes controls the growth of pre-implanted murine prostate cancer ⬇️

scientific article

Response: Sample size and statistical comparisons of GVHD rates in pediatric Niemann-Pick disease patients

scientific article published on January 2010

Robust CD4+ T-cell recovery in adults transplanted with cord blood and no antithymocyte globulin

scientific article published on 01 January 2020

Role of gut flora after bone marrow transplantation.

scientific article published on 29 March 2016

Role of intestinal microbiota in transplantation outcomes.

scientific article published in June 2015

STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease.

scientific article published on 06 October 2008

Selected biological issues affecting relapse after stem cell transplantation: role of T-cell impairment, NK cells and intrinsic tumor resistance.

scientific article

Sex steroid blockade enhances thymopoiesis by modulating Notch signaling

scientific article

Strategies to enhance T-cell reconstitution in immunocompromised patients

scientific article

Studies on mechanisms of augmentation of liver regeneration by cyclosporine and FK 506.

scientific article

Sublethal Total Body Irradiation Causes Long-Term Deficits in Thymus Function by Reducing Lymphoid Progenitors.

scientific article

Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury.

scientific article

T cell depleted stem-cell transplantation for adults with hematologic malignancies: sustained engraftment of HLA-matched related donor grafts without the use of antithymocyte globulin

scientific article

T cell regeneration after immunological injury

scientific article published on 23 October 2020

T cell-depleted stem cell transplantation for adults with high-risk acute lymphoblastic leukemia: long-term survival for patients in first complete remission with a decreased risk of graft-versus-host disease

scientific article published on 13 September 2012

T cell-depleted unrelated donor stem cell transplantation provides favorable disease-free survival for adults with hematologic malignancies

scientific article

T cells require TRAIL for optimal graft-versus-tumor activity

scientific article

TRAIL/ DR5 Interactions Are Important for Thymic Damage After Allogeneic Bone Marrow Transplantation. ⬇️

scholarly article

Targeted Sequencing Reveals a Relationship Between Mutational Burden and Clinical Phenotype in MPNs ⬇️

scholarly article

Targeted genomic analysis of cutaneous T cell lymphomas identifies a subset with aggressive clinicopathological features

scientific article published on 09 November 2020

Targeted ‘Off-the-Shelf’ Tumor Immunotherapy Using Allogeneic T-Cell Precursors. ⬇️

scholarly article

The 2008 education supplement on hematopoietic stem cell transplantation

scientific article published on 01 January 2008

The Abundance of Certain Bacteria in the Intestinal Flora Is Associated with Relapse after Allogeneic Hematopoietic Stem Cell Transplantation ⬇️

scholarly article

The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease

scientific article

The Intestinal Microbiota Correlates with Response and Toxicity after CAR T Cell Therapy in Patients with B-Cell Malignancies

scientific article published in 2021

The Microbiome and Hematopoietic Cell Transplantation: Past, Present, and Future

scientific article published on 19 February 2018

The Role of the Cytoplasmic RNA Sensor Retinoic Acid Inducible Gene- I (RIG-I) in Allogeneic Stem Cell Transplantation ⬇️

scholarly article

The central nervous system is a target of acute graft versus host disease in mice.

scientific article published on 8 January 2013

The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease

scientific article

The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation.

scientific article

The gut microbiota is associated with immune cell dynamics in humans

scientific article published on 25 November 2020

The importance of neovascularization and its inhibition for allogeneic hematopoietic stem cell transplantation ⬇️

scientific article published on January 21, 2011

The intestinal flora is required for post-transplant hematopoiesis in recipients of a hematopoietic stem cell transplantation

scientific article published on 01 August 2019

The intestinal microbiota in allogeneic hematopoietic cell transplant and graft-versus-host disease.

scientific article published on 9 December 2016

The role of pattern-recognition receptors in graft-versus-host disease and graft-versus-leukemia after allogeneic stem cell transplantation

scientific article

Therapeutics Targeting the Gut Microbiome: Rigorous Pipelines for Drug Development

scientific article published on 01 February 2020

Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity

scientific article published on 01 April 2018

Thymus: the next (re)generation

scientific article published on May 2016

Transforming lymph nodes into tissue factories ⬇️

scientific article published on 01 October 2012

Transplantation in remission improves the disease-free survival of patients with advanced myelodysplastic syndromes treated with myeloablative T cell-depleted stem cell transplants from HLA-identical siblings

scientific article published in April 2008

Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors

scientific article

Two Chemotherapy-Based Conditioning Regimens Compared To TBI-Based Conditioning Secure Consistent Engraftment Of T-Cell Depleted Allogeneic HSCT, Similarly Low Incidences Of Gvhd and Favorable Rates Of Disease-Free Survival (DFS) ⬇️

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Utility of Combined DNA and RNA Next Generation Sequencing in Leukemias for Identification of Prognostic and Therapeutically Relevant Genomic Alterations in Clinical Practice ⬇️

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Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans.

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WNT signaling suppression in the senescent human thymus.

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