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List of works by Issei Komuro

"Change can happen" by PKA: proteasomes in in vivo hearts

scientific article published on 31 December 2008

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors prevent the development of cardiac hypertrophy and heart failure in rats

scientific article published in August 2003

A Case of Multiple Coronary Artery-Left Ventricular Micro Fistulae Complicated With Hepatic Arteriovenous Fistulae

scientific article published on 6 January 2016

A DPP-4 inhibitor suppresses fibrosis and inflammation on experimental autoimmune myocarditis in mice

scientific article

A Development of Nucleic Chromatin Measurements as a New Prognostic Marker for Severe Chronic Heart Failure

scientific article (publication date: 2016)

A Food-Derived Flavonoid Luteolin Protects against Angiotensin II-Induced Cardiac Remodeling

scientific article published on September 2015

A Randomized Controlled Pilot Study of the Japanese Heart Failure Self-Management Program: Impacts on Heart Failure Knowledge and Clinical Outcomes

scientific article published in August 2013

A Strategy for Genomic Research on Common Cardiovascular Diseases Aiming at the Realization of Precision Medicine: Personal Insights and Perspectives

scientific article published in September 2016

A case of interferon-α-induced pulmonary arterial hypertension after living donor liver transplantation

scientific article published on 17 June 2015

A case with recovery of response to tolvaptan associated with remission of acute kidney injury and increased urine osmolality

scientific article published in January 2013

A crucial role of a high mobility group protein HMGA2 in cardiogenesis

scientific article

A crucial role of activin A-mediated growth hormone suppression in mouse and human heart failure

scientific article

A deleterious MYH11 mutation causing familial thoracic aortic dissection

scientific article published on 6 August 2015

A deletion mutation in myosin heavy chain 11 causing familial thoracic aortic dissection in two Japanese pedigrees

scientific article published on 3 June 2015

A functional SNP in FLT1 increases risk of coronary artery disease in a Japanese population

scientific article published on 21 January 2016

A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese

scientific journal article

A heart-brain-kidney network controls adaptation to cardiac stress through tissue macrophage activation

scientific article

A novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5

scientific article

A novel channelopathy in pulmonary arterial hypertension

scientific article published in November 2013

A novel mechanism of mechanical stress-induced angiotensin II type 1-receptor activation without the involvement of angiotensin II.

scientific article

A novel mutation of NFIX causes Sotos-like syndrome (Malan syndrome) complicated with thoracic aortic aneurysm and dissection

scientific article

A novel mutation of TGFBR2 causing Loeys-Dietz syndrome complicated with pregnancy-related fatal cervical arterial dissections

scientific article published on 8 August 2015

A novel susceptibility locus for Takayasu arteritis in the IL12B region can be a genetic marker of disease severity

scientific article published on 18 March 2015

A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction

scientific article published on 07 March 2017

A rare case of anomalous origin of the left anterior descending artery from the pulmonary artery

scientific article published on 27 December 2013

A role for bone morphogenetic protein signaling in cardiomyocyte differentiation

scientific article

A selective peroxisome proliferator-activated receptor-β/δ agonist attenuates neointimal hyperplasia after wire-mediated arterial injury

scientific article published on August 6, 2013

A subset of cerebrovascular pericytes originates from mature macrophages in the very early phase of vascular development in CNS.

scientific article

A subset of circulating microRNAs are predictive for cardiac death after discharge for acute myocardial infarction

article by Sen Matsumoto et al published October 2012 in Biochemical and Biophysical Research Communications

ACE inhibitor: characteristics, mechanisms of action, pharmacokinetics, indication, contraindication, clinical data, and side effects

scientific article

ARB and cardioprotection

scientific article published on April 2013

ATF6 is important under both pathological and physiological states in the heart

scientific article published on 7 April 2010

Abdominal aortic pseudoaneurysm caused by prolonged methicillin-resistant Staphylococcus aureus sepsis

scientific article published on 24 October 2007

Abdominal skeletal muscle mass as a predictor of mortality in Japanese patients undergoing left ventricular assist device implantation

scholarly article by Masaki Tsuji et al published June 2019 in ESC Heart Failure

Aberrant fistula arteries from the left main branch and right coronary artery to the left pulmonary arterial sinus demonstrated by multislice computed tomography

scientific article published in January 2006

Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload

scientific article

Abnormal collateral arterial systems in Takayasu's arteritis and Leriche's syndrome evaluated by whole body acquisition using multislice computed tomography

scientific article published on 5 December 2006

Ace inhibitors and angiotensin II receptor antagonists for therapy of chronic heart failure

scientific article

Activated β-catenin in Foxp3 regulatory T cells links inflammatory environments to autoimmunity

scientific article published on 29 October 2018

Activation of TGF-β signaling in an aortic aneurysm in a patient with Loeys-Dietz syndrome caused by a novel loss-of-function variant of

Activation of endothelial β-catenin signaling induces heart failure.

scientific article

Active myocarditis in a patient with chronic active Epstein-Barr virus infection

scientific article published on 25 October 2007

Acute Myocardial Infarction That Resulted From Poor Adherence to Medical Treatment for Giant Coronary Aneurysm

scientific article

Acute effect of oral vitamin C on coronary circulation in young healthy smokers

scientific article

Adipose Natural Regulatory B Cells Negatively Control Adipose Tissue Inflammation.

scientific article

Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes

scientific article

Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice

scientific article published on 30 January 2012

Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway

scientific article

Akt-induced cellular senescence: implication for human disease

scientific article published in April 2004

Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway

scientific article

An EP4 Receptor Agonist Inhibits Cardiac Fibrosis Through Activation of PKA Signaling in Hypertrophied Heart

scientific article published on 9 November 2016

An Experience of Landiolol Use for an Advanced Heart Failure Patient With Severe Hypotension

scientific article published on 11 September 2015

An elevated cibenzoline level interacted with cyclosporine caused ventricular tachyarrhythmia and high defibrillation threshold in hypertrophic cardiomyopathy

scientific article published on May 29, 2013

Anatomical remodeling of left atria in subjects with chronic and paroxysmal atrial fibrillation evaluated by multislice computed tomography

scientific article published on 24 October 2006

Angiogenesis and cardiac hypertrophy: maintenance of cardiac function and causative roles in heart failure

scientific article published on January 2014

Angiogenic potential of early and late outgrowth endothelial progenitor cells is dependent on the time of emergence

scientific article

Angiographic patterns of restenosis after sirolimus-eluting stent implantation

scientific article published on 16 January 2009

Angiopoietin-1 guides directional angiogenesis through integrin αvβ5 signaling for recovery of ischemic retinopathy.

scientific article published in September 2013

Angiopoietin-1 suppresses choroidal neovascularization and vascular leakage

scientific article

Angiosarcoma in the right atria demonstrated by fusion images of multislice computed tomography and positron emission tomography using F-18 Fluoro-Deoxyglucose

scientific article published on 20 February 2007

Angiotensin II impairs endothelial nitric-oxide synthase bioavailability under free cholesterol-enriched conditions via intracellular free cholesterol-rich membrane microdomains

scientific article

Angiotensin II receptor blockade promotes repair of skeletal muscle through down-regulation of aging-promoting C1q expression

scientific article

Angiotensin II receptor blocker irbesartan attenuates cardiac dysfunction induced by myocardial infarction in the presence of renal failure

scientific article

Angiotensin II type 1 and type 2 receptor-induced cell signaling

scientific article published on January 2013

Angiotensin II type 1 receptor signaling regulates feeding behavior through anorexigenic corticotropin-releasing hormone in hypothalamus

scientific article published on 27 April 2011

Angiotensin II type 1a receptor is involved in cell infiltration, cytokine production, and neovascularization in infarcted myocardium

scientific article published on 12 February 2004

Angiotensin II type 1a receptor mediates doxorubicin-induced cardiomyopathy

scientific article published in July 2002

Angiotensin II type 1a receptor signals are involved in the progression of heart failure in MLP-deficient mice

scientific article

Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling

scientific article published in December 2002

Anti-inflammatory peptides from cardiac progenitors ameliorate dysfunction after myocardial infarction

scientific article

Anti-salusin-β antibody enhances angiogenesis after myocardial ischemia reperfusion injury

scientific article published on July 19, 2013

Antiplatelet effect of 50-mg maintenance dose of clopidogrel compared to 200 mg ticlopidine: a preliminary study

scientific article published on 21 January 2010

Antisenescence as a novel therapeutic strategy for vascular aging

scientific article

Apolipoprotein B-48 to triglyceride ratio is a novel and useful marker for detection of type III hyperlipidemia after antihyperlipidemic intervention

scientific article published on 9 August 2012

Application of hematopoietic cells to therapeutic angiogenesis

scientific article

Assessment of inverse agonism for the angiotensin II type 1 receptor

scientific article published on January 2010

Assessment of quality of life during long-term treatment of tolvaptan in refractory heart failure: design and rationale of the AQUA-TLV study

scientific article published on 7 May 2014

Assessment of regional myocardial strain by a novel automated tracking system from digital image files

scientific article

Association between serum IgG4 concentrations and the morphology of the aorta in patients who undergo cardiac computed tomography

scientific article published in July 2014

Association between the docosahexaenoic acid to arachidonic acid ratio and acute coronary syndrome: a multicenter observational study

scientific article

Association of Stat3 with HSF1 plays a critical role in G-CSF-induced cardio-protection against ischemia/reperfusion injury

scientific article published on March 6, 2012

Association of serum IgG4 and soluble interleukin-2 receptor levels with epicardial adipose tissue and coronary artery calcification

scientific article published on 24 October 2013

Ataxia telangiectasia mutated in cardiac fibroblasts regulates doxorubicin-induced cardiotoxicity

scientific article published on 9 February 2016

Atherosclerotic right internal thoracic arterial aneurysm demonstrated by multislice computed tomography

scientific article published in January 2006

Atrial natriuretic peptide inhibits cardiomyocyte hypertrophy through mitogen-activated protein kinase phosphatase-1.

scientific article

Attenuated defense response and low basal blood pressure in orexin knockout mice

scientific article published on May 15, 2003

Attenuation of ischemia/reperfusion-induced renal injury in mice deficient in Na+/Ca2+ exchanger

scientific article

Author Correction: Activation of endothelial β-catenin signaling induces heart failure

scientific article published in Scientific Reports

Authors' response to "Compound heterozygous Fukutin mutation-related non-compaction" by Finsterer and Zarrouk-Mahjoub

scientific article published in April 2017

Bare metal stent restenosis is benign clinical entity in Japanese patients

scientific article published in July 2010

Beating is necessary for transdifferentiation of skeletal muscle‐derived cells into cardiomyocytes

scientific article published on May 8, 2003

Beta-blockers have beneficial effects even on unclassified cardiomyopathy such as isolated ventricular noncompaction.

scientific article

Bevacizumab-Related Microvascular Angina and Its Management with Nicorandil

scientific article

Biased Agonism at the Angiotensin Receptor: Blocker and Calcium Sensitizer at the Same Time

scientific article published in March 2017

Biased Agonism of the Angiotensin II Type I Receptor

scientific article (publication date: 2015)

Blood lipid-related low-frequency variants in LDLR and PCSK9 are associated with onset age and risk of myocardial infarction in Japanese.

scientific article published on 25 May 2018

Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway

scientific article published on 3 May 2012

Btg2 is a Negative Regulator of Cardiomyocyte Hypertrophy through a Decrease in Cytosolic RNA.

scientific article published on 27 June 2016

Buerger's disease-like vasculitis associated with Kimura's disease

scientific article published on 7 January 2009

CHARM study--new strategy for the treatment of heart failure

scientific article

Calpain Protects the Heart from Hemodynamic Stress

scientific article published on July 27, 2011

Calpain-dependent cleavage of N-cadherin is involved in the progression of post-myocardial infarction remodeling

scientific article published on 2 June 2014

Can nifedipine prevent aging of blood vessels?

scientific article published in January 2006

Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure

scientific article published on 22 June 2009

Cardiac Rehabilitation Protects Against the Expansion of Abdominal Aortic Aneurysm.

scientific article published on 27 February 2018

Cardiac Resynchronization Therapy in Patients with Ebstein's Anomaly

scientific article

Cardiac Sarcoidosis Diagnosed by Incidental Lymph Node Biopsy

scientific article published on 24 January 2017

Cardiac Side Population Cells and Sca-1-Positive Cells

scientific article published on January 1, 2013

Cardiac compression by massive mediastinal haematoma due to bleeding from the ectopic bronchial artery

scientific article

Cardiac developmental biology: from flies to humans

scientific article published in October 2005

Cardiac macrophages prevent sudden death during heart stress

scientific article published on 26 March 2021

Cardiac mast cells cause atrial fibrillation through PDGF-A-mediated fibrosis in pressure-overloaded mouse hearts

scientific article published on 21 December 2009

Cardiac rehabilitation increases exercise capacity with a reduction of oxidative stress

scientific article published on 31 July 2013

Cardiac sarcoidosis complicated with atrioventricular block and wall thinning, edema and fibrosis in left ventricle: confirmed recovery to normal sinus rhythm and visualization of edema improvement by administration of predonisolone

scientific article published on 18 June 2009

Cardiac sarcoidosis evaluated by multimodality imaging

scientific article published on 12 January 2010

Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo

scientific article published in January 2007

Cardiac transcription factor Csx/Nkx2-5: Its role in cardiac development and diseases

scientific article

Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure

scientific article published in Nature Communications

Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle

scientific article published on 18 October 2004

Cardiovascular circulation and hepatic perfusion of pigs in 4-dimensional films evaluated by 256-slice cone-beam computed tomography

scientific article published in May 2005

Cdc42 plays a critical role in assembly of sarcomere units in series of cardiac myocytes

scientific article published in June 2003

Cell therapy for cardiovascular diseases

scientific article published on 24 October 2008

Channel-like appearance of a patent foramen ovale with left to right shunt demonstrated by 64-slice computed tomography

scientific article published on 12 October 2006

Characteristic effects of alpha1-beta1,2-adrenergic blocking agent, carvedilol, on [Ca2+]i in ventricular myocytes compared with those of timolol and atenolol

scientific article

Characterization and morphology of atherosclerotic plaque of coronary arteries: utility of electron-beam tomography to detect non-calcified plaque: a comparison with conventional coronary angiography and intravascular ultrasound

scientific article published on 5 June 2006

Characterization of a novel C. elegans RGS protein with a C2 domain: evidence for direct association between C2 domain and Galphaq subunit

scientific article

Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity

scientific article published on 3 August 2009

Circulating p53-responsive microRNAs are predictive indicators of heart failure after acute myocardial infarction

scientific article published on 6 June 2013

Class- and Molecule-specific Differential Effects of Angiotensin II Type 1 Receptor Blockers

scientific article published on January 1, 2013

Clinical correlation of brachial artery flow-mediated dilation in patients with systemic sclerosis

scientific article

Coarctation of the descending aorta, patent ductus arteriosus, deficiency of right superior vena cava, and persistent left superior vena cava in a five-month infant demonstrated by multislice computed tomography

scientific article published on 6 December 2006

Comparison between nicorandil and magnesium as an adjunct cardioprotective agent to percutaneous coronary intervention in acute anterior myocardial infarction

scientific article published in March 2004

Comparison of 5-year survival after acute myocardial infarction using angiotensin-converting enzyme inhibitor versus angiotensin II receptor blocker

scientific article published on 18 April 2014

Comparison of angiotensin II type 1-receptor blockers to regress pressure overload-induced cardiac hypertrophy in mice

scientific article published on October 14, 2010

Competing risks of heart failure with preserved ejection fraction in diabetic patients

scientific article published on March 17, 2011

Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes

scientific article

Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling

scientific article published on 26 February 2015

Complete left bundle branch block and smaller left atrium are predictors of response to cardiac resynchronization therapy in advanced heart failure

scientific article published on 17 September 2015

Complications of pulmonary vein isolation by catheter ablation evaluated by ECG-gated multislice computed tomography

scientific article published on September 1, 2003

Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation

scientific article

Continuous blockade of L-type Ca2+ channels suppresses activation of calcineurin and development of cardiac hypertrophy in spontaneously hypertensive rats

scientific article

Coronary Artery Aneurysm Caused by a Stent Fracture

scientific article published in January 2018

Coronary Artery Endothelial Dysfunction Associated With Sleep Apnea

scientific article published on February 8, 2011

Coronary aneurysm reduced after coronary stenting

scientific article published on 13 November 2006

Coronary atherosclerotic lesions in patients with a ruptured abdominal aortic aneurysm

scientific article published on 7 March 2014

Correct Diagnosis of Wild-Type Transthyretin-Related Amyloidosis Followed by the Introduction of a Novel Therapy in a Patient With Cardiac Wall Thickening of Unknown Cause

scientific article published on 20 January 2017

Correction

scholarly article published in Journal of Cell Biology

Correction to: High-intensity aerobic interval training can lead to improvement in skeletal muscle power among in-hospital patients with advanced heart failure

scientific article published on 20 February 2018

Correction: Establishment of a Novel Murine Model of Ischemic Cardiomyopathy with Multiple Diffuse Coronary Lesions.

scientific article published on 27 August 2013

Correction: Small Molecules with Similar Structures Exhibit Agonist, Neutral Antagonist or Inverse Agonist Activity toward Angiotensin II Type 1 Receptor.

scientific article published on 3 May 2013

Correlation of fasting serum apolipoprotein B-48 with coronary artery disease prevalence

scientific article published on 15 May 2012

Corrigendum: Cacao polyphenols ameliorate autoimmune myocarditis in mice

scientific article published on November 2016

Cost analysis of sirolimus-eluting stents in the Japanese health insurance system

scientific article published in November 2009

Cost effectiveness of transcatheter aortic valve implantation in patients with aortic stenosis in Japan

scientific article

Cost-Effectiveness Analysis of Cardiovascular Disease Treatment in Japan

scientific article published on 17 November 2017

Cost-Effectiveness of Statin Plus Eicosapentaenoic Acid Combination Therapy for Cardiovascular Disease Prevention in Japanese Patients With Hypercholesterolemia - An Analysis Based on the Japan Eicosapentaenoic Acid Lipid Intervention Study (JELIS).

scientific article published on 23 January 2018

Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization.

scientific article

Csx/Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart

scientific article

Current Practices in the Management of Antithrombotic Therapy During the Periendoscopic Period for Patients With Cardiovascular Disease

scientific article published on September 2016

Current therapies and investigational drugs for peripheral arterial disease

scientific article

Cytokine therapy prevents left ventricular remodeling and dysfunction after myocardial infarction through neovascularization

scientific article published on 4 March 2004

DNA single-strand break-induced DNA damage response causes heart failure

scientific article published on 24 April 2017

DPP-4 inhibition has beneficial effects on the heart after myocardial infarction

scientific article published on 28 December 2015

Damage to polymer of paclitaxel-eluting stent

scientific article published on 11 September 2008

Decreased mortality associated with statin treatment in patients with acute myocardial infarction and lymphotoxin-alpha C804A polymorphism

Deficiency of Myo18B in mice results in embryonic lethality with cardiac myofibrillar aberrations

scientific journal article

Deletion of progranulin exacerbates atherosclerosis in ApoE knockout mice

scientific article published on 11 July 2013

Detailed distribution of acute pulmonary thromboemboli: direct evidence for reduction of acquisition length and radiation dose for triple rule-out CT angiography

scientific article published on 08 September 2009

Detection of Takayasu arteritis in early stage by computed tomography

scientific article published in October 2002

Detection of experimental autoimmune myocarditis in rats by 111In monoclonal antibody specific for tenascin-C.

scientific article published in September 2002

Detrimental effects of specific Periodontopathic bacterial infection on tachyarrhythmia compared to Bradyarrhythmia

scientific article published on 17 October 2017

Development and psychometric properties of the Japanese heart failure knowledge scale

scientific article published in January 2013

Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis

scholarly article

Diabetic Retinopathy is Associated With Impaired Left Ventricular Relaxation

scientific article published on April 22, 2011

Diagnostic implication of change in b-type natriuretic peptide (BNP) for prediction of subsequent target lesion revascularization following silorimus-eluting stent deployment

scientific article

Differences in body temperature variability between subjects with and without diabetes and predictive value for cardiovascular events

scientific article published on 27 March 2013

Different Contributions of Physical Activity on Arterial Stiffness between Diabetics and Non-Diabetics

scientific article

Differentiation of pseudodyskinesis of inferior left ventricular wall from inferior myocardial infarction by assessment of regional myocardial strain using two-dimensional speckle tracking echocardiography

scientific article published on September 9, 2010

Dilated cardiomyopathy complicated with visceral heterotaxy

scientific article published on 13 October 2017

Dilated cardiomyopathy with centronuclear myopathy in a young male

Direct measurement of Ca2+ concentration in the SR of living cardiac myocytes

scientific article published in February 2004

Direction, location, and size of shunt flow in congenital heart disease evaluated by ECG-gated multislice computed tomography

scientific article published on 7 November 2005

Distinguishing focal fibrotic lesions and non-fibrotic lesions in hypertrophic cardiomyopathy by assessment of regional myocardial strain using two-dimensional speckle tracking echocardiography: Comparison with multislice CT

scientific article published on February 26, 2011

Diverse contribution of bone marrow-derived late-outgrowth endothelial progenitor cells to vascular repair under pulmonary arterial hypertension and arterial neointimal formation

scientific article published on 28 July 2015

Do not forget vasospastic angina in patients with chest pain at rest and no significant coronary stenosis with multidetector computed tomography

scientific article published in May 2008

Docking protein Gab1 is an essential component of postnatal angiogenesis after ischemia via HGF/c-met signaling.

scientific article

Donor age is a predictor of early low output after heart transplantation

scientific article published on 10 August 2015

Double outlet right ventricle demonstrated by multislice computed tomography

scientific article published on 28 November 2006

Double-Blind, Randomized, Placebo-Controlled Trial Evaluating the Efficacy and Safety of Eplerenone in Japanese Patients With Chronic Heart Failure (J-EMPHASIS-HF).

scientific article

Drug therapies following heart failure and myocardial infarction(discussion)

scientific article published in June 2002

Dual effects of the homeobox transcription factor Csx/Nkx2-5 on cardiomyocytes

scientific article published on November 2002

Early stage-specific inhibitions of cardiomyocyte differentiation and expression of Csx/Nkx-2.5 and GATA-4 by phosphatidylinositol 3-kinase inhibitor LY294002.

scientific article published on November 2003

Effect of 150-mg vs 300-mg loading doses of clopidogrel on platelet function in Japanese patients undergoing coronary stent placement

scientific article published in August 2008

Effect of 450-mg loading dose of clopidogrel on platelet function in Japanese patients undergoing coronary stent placement

scientific article published on 29 May 2010

Effect of Statin Treatment and Low-Density Lipoprotein-Cholesterol on Short-Term Mortality in Acute Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention - Multicenter Registry From Tokyo CCU Network Database

scientific article

Effect of angiotensin-converting enzyme inhibitor on serum asymmetric dimethylarginine and coronary circulation in patients with type 2 diabetes mellitus

scientific article

Effect of balloon inflation time on expansion of sirolimus-eluting stent

scientific article published on 27 September 2009

Effect of coronary stent overexpansion on lumen size and intimal hyperplasia at follow-up

scientific article published in June 2002

Effect of hydrochlorothiazide in addition to telmisartan/amlodipine combination for treating hypertensive patients uncontrolled with telmisartan/amlodipine: a randomized, double-blind study

scientific article

Effect of mechanical stress on blood vessels

scientific article published in March 2004

Effect of mental stress on coronary flow velocity reserve in healthy men.

scientific article published in July 2005

Effect of periodontitis on cardiovascular manifestations in Marfan syndrome. Critical common role of TGF-β

scientific article

Effect of plaque volume on subsequent vessel remodeling at edges of sirolimus-eluting stents

scientific article published on 28 August 2006

Effect of purified eicosapentaenoic acid on red cell distribution width in patients with ischemic heart disease

scientific article published on 31 May 2014

Effects of G-CSF on left ventricular remodeling and heart failure after acute myocardial infarction

scientific article

Effects of antiarrhythmic drugs on the hyperpolarization-activated cyclic nucleotide-gated channel current

scientific article

Effects of methylglyoxal on human cardiac fibroblast: roles of transient receptor potential ankyrin 1 (TRPA1) channels

scientific article published on 29 August 2014

Effects of stem cell mobilization by granulocyte colony-stimulating factor on endothelial function after sirolimus-eluting stent implantation: a double-blind, randomized, placebo-controlled clinical trial

scientific article published on 22 January 2013

Effects of valsartan and amlodipine on cardiorenal protection in Japanese hypertensive patients: the Valsartan Amlodipine Randomized Trial

retracted scientific article published on 7 October 2010

Elevated C-reactive protein levels and enhanced high frequency vasomotion in patients with ischemic heart disease during brachial flow-mediated dilation

scientific article

Elevated Serum Heart-Type Fatty Acid-Binding Protein in the Convalescent Stage Predicts Long-Term Outcome in Patients Surviving Acute Myocardial Infarction

scientific article published on December 29, 2012

Emergency percutaneous coronary intervention for left main trunk thrombus following orthotopic heart transplantation

Endoluminal perspective volume rendering of coronary arteries using electron-beam computed tomography

scientific article published in December 2003

Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease

scientific article published on October 2010

Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction

scientific article

Endovascular aortic repair increases vascular stiffness and alters cardiac structure and function

scientific article published on 29 November 2013

Enhancement of arterial pulsation during flow-mediated dilation is impaired in the presence of ischemic heart disease

scientific article published on 16 July 2016

Epidemiology of fat replacement of the right ventricular myocardium determined by multislice computed tomography using a logistic regression model

scientific article published on 24 October 2006

Establishment of a novel murine model of ischemic cardiomyopathy with multiple diffuse coronary lesions

scientific article

Establishment of chemiluminescence enzyme immunoassay for apolipoprotein B-48 and its clinical applications for evaluation of impaired chylomicron remnant metabolism

scientific article published on 19 September 2011

Estimate of organ radiation absorbed doses in clinical CT using the radiation treatment planning system

scientific article published on 10 August 2010

Estimation of Left Atrial Pump Function by Mitral Annular Velocity

scientific article published on March 8, 2012

Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation

scientific article

Everolimus-incorporated immunosuppressant strategy improves renal dysfunction while maintaining low rejection rates after heart transplantation in Japanese patients

scientific article published in January 2013

Examination of beam profile measurement using an imaging plate by the light exposure fading method for quality assurance of external radiation therapy.

scientific article published on December 2006

Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents

scientific article published on 19 April 2010

Excitation propagation in three-dimensional engineered hearts using decellularized extracellular matrix

scientific article published on 20 June 2014

Exercise echocardiography in the evaluation of severity of functional mitral regurgitation in patients with heart failure

scientific article

Expression of MAK-V/Hunk in renal distal tubules and its possible involvement in proliferative suppression

scientific article published on 13 February 2007

Fasting Serum Apolipoprotein B-48 Can be a Marker of Postprandial Hyperlipidemia

scientific article published on September 24, 2011

Fatal very late stent thrombosis in a young diabetic patient with severely diffuse coronary atherosclerosis

scientific article published in July 2008

Feasibility of Extracorporeal Shock Wave Myocardial Revascularization Therapy for Post-Acute Myocardial Infarction Patients and Refractory Angina Pectoris Patients

scientific article

Feeding artery of a recurrent pheochromocytoma from the left internal thoracic artery demonstrated by multislice computed tomography

scientific article published in May 2006

Fenofibrate reduces postprandial hypertriglyceridemia in CD36 knockout mice

scientific article published on 30 March 2010

Focal fibrosis in the left ventricle of subjects with cardiac amyloidosis evaluated by multislice computed tomography

scientific article

Focal myocardial fibrosis and edema in acute myocarditis demonstrated by multislice computed tomography

scientific article published in December 2005

Forefront of Na+/Ca2+ exchanger studies: role of Na+/Ca2+ exchanger--lessons from knockout mice

scientific article published on 10 September 2004

Fukutin gene mutations that cause left ventricular noncompaction

scientific article published on 3 August 2016

G-CSF therapy for acute myocardial infarction

scientific article published on 20 September 2007

Gab Docking Proteins in Cardiovascular Disease, Cancer, and Inflammation

scientific article published on January 22, 2013

Gene and cytokine therapy for heart failure: molecular mechanisms in the improvement of cardiac function

scientific article published on 09 July 2012

Gene expression profile revealed different effects of angiotensin II receptor blockade and angiotensin-converting enzyme inhibitor on heart failure.

scientific article published in December 2003

Generation of Induced Pluripotent Stem Cells From Patients With Duchenne Muscular Dystrophy and Their Induction to Cardiomyocytes

scientific article published on 17 December 2015

Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling

scientific article published on 31 January 2018

Giant coronary sinus diverticulum with persistent left superior vena cava demonstrated by multislice computed tomography

scientific article published on 11 October 2005

Giant left atrial myxoma that caused mitral valve obstruction and pulmonary hypertension

scientific article

Glucocorticoids Induce Cardiac Fibrosis via Mineralocorticoid Receptor in Oxidative Stress: Contribution of Elongation Factor Eleven-Nineteen Lysine-Rich Leukemia (ELL).

scientific article

Gremlin enhances the determined path to cardiomyogenesis

scientific article

HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus

scientific article published on 25 February 2008

Heart Failure as an Aging-Related Phenotype

scientific article published on 15 January 2018

Higd1a is a positive regulator of cytochrome c oxidase

scientific article

High Dose β-Blocker Therapy Triggers Additional Reverse Remodeling in Patients With Idiopathic Non-Ischemic Cardiomyopathy

scientific article published on 4 November 2016

High incidence and severity of periodontitis in patients with Marfan syndrome in Japan

scientific article

High incidence of periodontitis in Japanese patients with abdominal aortic aneurysm

scientific article

High-intensity aerobic interval training can lead to improvement in skeletal muscle power among in-hospital patients with advanced heart failure

scientific article published on 15 January 2018

How Should We Treat Early Post-Transplant Lymphoproliferative Disease After Heart Transplantation?

scientific article

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

scientific article

IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs

scientific article

IL-6-mediated Th17 differentiation through RORγt is essential for the initiation of experimental autoimmune myocarditis

scientific article published on 27 May 2011

Identification of MYLK3 mutations in familial dilated cardiomyopathy

scientific article published on 13 December 2017

Identification of a novel compound that inhibits both mitochondria-mediated necrosis and apoptosis

scientific article published on 8 October 2015

Identification of the State of Maximal Hyperemia in the Assessment of Coronary Fractional Flow Reserve Using Non-Invasive Electrical Velocimetry

scientific article published on 23 May 2017

Images in cardiovascular medicine. Coronary artery patency after metallic stent implantation evaluated by multislice computed tomography

scientific article published in January 2003

Images in cardiovascular medicine. Damage to polymer of a sirolimus-eluting stent

scientific article published in November 2006

Images in cardiovascular medicine. Demonstration of multislice computed tomography of graft destruction and rupture to the pericardium after replacement of ascending aorta for stanford type-a dissection

scientific article

Images in cardiovascular medicine. Double aortic arch with a compressed trachea demonstrated by multislice computed tomography

scientific article

Images in cardiovascular medicine. Feeding artery of a left atrial myxoma demonstrated by three-dimensional volume-rendering images with multislice computed tomography

scientific article published in October 2002

Images in cardiovascular medicine. Multiple ruptured plaques: serial intravascular ultrasound examinations

scientific article published in November 2003

Images in cardiovascular medicine. Myocardial fibrosis in fabry disease demonstrated by multislice computed tomography: comparison with biopsy findings

scientific article published in May 2003

Images in cardiovascular medicine. Occurrence of multiple fibrofatty replacements exclusively in the left ventricle of a patient with monomorphic sustained ventricular tachycardia

scientific article published in June 2007

Images in cardiovascular medicine. Right-sided heart wall thickening and delayed enhancement caused by chronic active myocarditis complicated by sustained monomorphic ventricular tachycardia

scientific article published in February 2009

Images in cardiovascular medicine. Transition from left ventricular hypertrophy to massive fibrosis in the cardiac variant of Fabry disease

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Images in clinical medicine. Heart-shaped tumor in pulmonary trunk

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Immunoglobulin G4-related Coronary Periarteritis and Luminal Stenosis in a Patient with a History of Autoimmune Pancreatitis

scientific article published on 21 August 2017

Impact of Body Size on Inferior Vena Cava Parameters for Estimating Right Atrial Pressure: A Need for Standardization?

scientific article published on 10 August 2015

Impact of Oral Treatment on Physical Function in Older Patients Hospitalized for Heart Failure: A Randomized Clinical Trial

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Impact of beta blockade therapy on long-term mortality after ST-segment elevation acute myocardial infarction in the percutaneous coronary intervention era.

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Impact of coronary collaterals on in-hospital and 5-year mortality after ST-elevation myocardial infarction in the contemporary percutaneous coronary intervention era: a prospective observational study

scientific article published on 13 July 2016

Impact of drug-eluting stents on clinical and angiographic outcomes in dialysis patients

scientific article published in October 2007

Impact of pulmonary vein isolation on atrial late potentials: association with the recurrence of atrial fibrillation

scientific article published on October 11, 2012

Impact of the distance from the stent edge to the residual plaque on edge restenosis following everolimus-eluting stent implantation

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Impairment factors for evaluating the patency of drug-eluting stents and bare metal stents in coronary arteries by 64-slice computed tomography versus conventional coronary angiography

scientific article published on 3 January 2008

Impairment of flow-mediated dilation correlates with aortic dilation in patients with Marfan syndrome

scientific article published on 14 July 2013

Implantation of cardiac progenitor cells using self-assembling peptide improves cardiac function after myocardial infarction

scientific article published on September 24, 2010

Implication of cardiac remodeling in heart failure: mechanisms and therapeutic strategies.

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Improved Diagnosis of Detection of Late Enhancement in Left Ventricular Myocardium Using 2nd Generation 320-Slice CT Reconstructed with FIRST in Non-Ischemic Cardiomyopathy

scientific article published on 20 April 2018

Improvement of Severe Heart Failure after Endovascular Stent Grafting for Thoracic Aortic Aneurysm

scientific article published on 6 November 2015

In vitro platform of allogeneic stem cell-derived cardiomyocyte transplantation for cardiac conduction defects

scientific article published on 15 March 2018

In vivo tracking of transplanted mononuclear cells using manganese-enhanced magnetic resonance imaging (MEMRI)

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In-stent restenosis exacerbated by drug-induced severe eosinophilia after second-generation drug-eluting stent implantation

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Incidence of premature discontinuation of antiplatelet therapy after sirolimus-eluting stent implantation

scientific article published in February 2008

Incidence of side-effects of ticlopidine after sirolimus-eluting stent implantation

scientific article published in April 2007

Incidence, Predictors, and Subsequent Mortality Risk of Recurrent Myocardial Infarction in Patients Following Discharge for Acute Myocardial Infarction

scientific article published on October 17, 2012

Increased Akt-mTOR Signaling in Lung Epithelium Is Associated with Respiratory Distress Syndrome in Mice

scientific article published on December 28, 2010

Increased subcutaneous fat accumulation has a protective role against subclinical atherosclerosis in asymptomatic subjects undergoing general health screening

scientific article published in July 2008

Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia

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Influence of heart rate on the detectability and reproducibility of multislice computed tomography for measuring coronary calcium score using a pulsating calcified mock-vessel in comparison with electron beam tomography

scientific article published on 17 November 2005

Influence of municipality-level mean income on access to aortic valve surgery: a cross-sectional observational study under Japan's universal health-care coverage

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Inhibition of NF-κB activation by a novel IKK inhibitor reduces the severity of experimental autoimmune myocarditis via suppression of T-cell activation

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Inhibition of semaphorin as a novel strategy for therapeutic angiogenesis

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Inhibitory effect of the class III antiarrhythmic drug nifekalant on HERG channels: mode of action

scientific article published in December 2002

Inhibitory effects of AMP 579, a novel cardioprotective adenosine A1/A2A receptor agonist, on native IKr and cloned HERG current

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Inhibitory molecules in signal transduction pathways of cardiac hypertrophy

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Insufficient self-care is an independent risk factor for adverse clinical outcomes in Japanese patients with heart failure

scientific article published in January 2013

Integrins play a critical role in mechanical stress-induced p38 MAPK activation

scientific article published in February 2002

Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy

scientific article published on 8 September 2009

Interleukin-16 Promotes Cardiac Fibrosis and Myocardial Stiffening in Heart Failure with Preserved Ejection Fraction

scientific article published on July 19, 2013

Interleukin-6/interleukin-21 signaling axis is critical in the pathogenesis of pulmonary arterial hypertension

scientific article published on 4 May 2015

Inverse Correlation Between Calcium Accumulation and the Expansion Rate of Abdominal Aortic Aneurysms

scientific article published on 7 December 2015

Involvement of Na+/Ca2+ exchanger in pentylenetetrazol-induced convulsion by use of Na+/Ca2+ exchanger knockout mice

scientific article published in November 2009

Is Achieved Heart Rate a Surrogate Maker during Titration of Beta-blocker in Heart Failure with Atrial Fibrillation?

scientific article published in August 2013

Is it possible to perform gastric endoscopic submucosal dissection without discontinuation of a single antiplatelet of thienopyridine derivatives?

scientific article published on 13 September 2017

Isoform-specific Intermolecular Disulfide Bond Formation of Heterochromatin Protein 1 (HP1)

scientific article published on October 8, 2010

Japanese Cardiovascular Disease Patients with Diabetes Mellitus Suffer Increased Tooth Loss in Comparison to Those without Diabetes Mellitus -A Cross-sectional Study

scientific article published on 20 November 2017

Kir6.2-deficient mice are susceptible to stimulated ANP secretion: K(ATP) channel acts as a negative feedback mechanism?

scientific article published on 20 April 2005

Knockdown of nucleosome assembly protein 1-like 1 induces mesoderm formation and cardiomyogenesis via notch signaling in murine-induced pluripotent stem cells

scientific article published in July 2014

Laparoscopic resection of a gastrointestinal stromal tumor of the lower rectum in a patient with coronary artery disease following long-term neoadjuvant imatinib treatment and anticoagulation therapy

scientific article published on 15 July 2014

Large collateral conus branch to the left anterior descending branch of the coronary artery in a subject with angina pectoris demonstrated by multislice computed tomography

scientific article published in August 2005

Late stent thrombosis in patients receiving ticlopidine and aspirin after sirolimus-eluting stent implantation

scientific article published in January 2008

Left atrial compensatory function in subjects with early stage primary hypertension assessed by using left atrial volumetric emptying fraction acquired by transthoracic echocardiography

scientific article published on 3 August 2008

Left atrial wall thickness in paroxysmal atrial fibrillation by multislice-CT is initial marker of structural remodeling and predictor of transition from paroxysmal to chronic form

scientific article published on 10 November 2009

Leukemia Inhibitory Factor Enhances Endogenous Cardiomyocyte Regeneration after Myocardial Infarction

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Leukemia inhibitory factor enhances survival of cardiomyocytes and induces regeneration of myocardium after myocardial infarction

scientific article published on 14 July 2003

Liposomal Amiodarone Augments Anti-arrhythmic Effects and Reduces Hemodynamic Adverse Effects in an Ischemia/Reperfusion Rat Model

scientific article published on April 1, 2013

Living alone and risk of cardiovascular events following discharge after acute myocardial infarction in Japan

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Long-Term Adaptive Servo-Ventilator Treatment Prevents Cardiac Death and Improves Clinical Outcome

scientific article published on 8 January 2016

Long-term clinical outcomes after sirolimus-eluting stent implantation in dialysis patients

scientific article published in March 2010

Long-term outcome of therapeutic neovascularization using peripheral blood mononuclear cells for limb ischemia

scientific article published on 30 March 2009

Longitudinal Risk of Cardiovascular Events in Relation to Depression Symptoms After Discharge Among Survivors of Myocardial Infarction - Osaka Acute Coronary Insufficiency Study (OACIS) -

scientific article published on September 21, 2011

Low Blood Pressure, Low Serum Cholesterol and Anemia Predict Early Necessity of Ventricular Assist Device Implantation in Patients With Advanced Heart Failure at the Time of Referral From Non-Ventricular Assist Device Institutes

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Low blood pressure, low serum cholesterol and anemia predict early necessity of ventricular assist device implantation in patients with advanced heart failure at the time of referral from non-ventricular assist device institutes

scientific article published on 30 October 2014

Low cardiac output stimulates vasopressin release in patients with stage d heart failure

scientific article published on 10 July 2014

Low-Dose Erythropoietin in Patients With ST-Segment Elevation Myocardial Infarction (EPO-AMI-II) - A Randomized Controlled Clinical Trial

scientific article published on 2 February 2018

Malformation of abdominal arteries in Takayasu's arteritis demonstrated by multislice computed tomography

scientific article published in April 2006

Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II.

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Mechanisms and functions of agonist-independent activation in the angiotensin II type 1 receptor

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Melatonin ameliorates angiotensin II-induced vascular endothelial damage via its antioxidative properties

scientific article published in July 2013

Midterm outcome of implantable left ventricular assist devices as a bridge to transplantation: Single-center experience in Japan

scientific article published on 14 July 2014

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

scientific article published on May 10, 2012

Mitochondrial aldehyde dehydrogenase 2 plays protective roles in heart failure after myocardial infarction via suppression of the cytosolic JNK/p53 pathway in mice

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Molecular Characterization of Striated Muscle-Specific Gab1 Isoform as a Critical Signal Transducer for Neuregulin-1/ErbB Signaling in Cardiomyocytes

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Molecular and cellular mechanisms of mechanical stress-induced cardiac hypertrophy

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Molecular mechanisms of ezetimibe-induced attenuation of postprandial hypertriglyceridemia

scientific article published on 11 June 2010

Molecular mechanisms underlying the transition of cardiac hypertrophy to heart failure

scientific article published on 05 September 2008

Monocyte-derived extracellular Nampt-dependent biosynthesis of NAD(+) protects the heart against pressure overload

scientific article published on 2 November 2015

Multivalent ligand-receptor interactions elicit inverse agonist activity of AT(1) receptor blockers against stretch-induced AT(1) receptor activation

scientific article published on 7 August 2009

Multivessel coronary artery spasm refractory to intensive medical treatment

scientific article published on 28 September 2007

Myocardial energy provision is preserved by increased utilization of glucose and ketone bodies in CD36 knockout mice

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Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart

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Na+/Ca2+ exchanger-deficient mice have disorganized myofibrils and swollen mitochondria in cardiomyocytes

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Navigational error in the heart leads to premature ventricular excitation

scientific article published on 25 January 2011

Neovascularization induced by hypoxia inducible transcription factor is associated with the improvement of cardiac dysfunction in experimental autoimmune myocarditis

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New classification of aortic dissection during the cardiac cycle as pulsating type and static type evaluated by electrocardiogram-gated multislice CT.

scientific article published on 3 February 2009

New mechanism of heart protection by angiotensin receptor blockers.

scientific article published on December 2006

Newly developed atrial fibrillation progresses to a more severe INTERMACS score in a patient with advanced heart failure due to dilated cardiomyopathy

scientific article published in November 2017

Nickel-free stainless steel avoids neointima formation following coronary stent implantation

scientific article published on 28 December 2012

Non-calcified plaques of coronary arteries with obvious outward remodeling demonstrated by multislice computed tomography

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Noninvasive detection of cardiac repair after acute myocardial infarction in rats by 111 In Fab fragment of monoclonal antibody specific for tenascin-C.

scientific article published in July 2008

Notch activation mediates angiotensin II-induced vascular remodeling by promoting the proliferation and migration of vascular smooth muscle cells

scientific article published on 30 May 2013

Novel Concept of a Heart-Gut Axis in the Pathophysiology of Heart Failure

scientific article published on 23 August 2017

Novel molecular mechanisms and regeneration therapy for heart failure

scientific article published on 29 January 2016

Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease

scientific article (publication date: June 2002)

Novel scoring system using cardiopulmonary exercise testing predicts prognosis in heart failure patients receiving guideline-directed medical therapy

scientific article published on 16 February 2015

Occurrence of lung tumor between internal thoracic arterial and saphenous vein grafts to coronary arteries demonstrated by multislice computed tomography

scientific article published on 24 June 2005

Optical coherence tomography and intravascular ultrasound evaluation of cardiac allograft vasculopathy with and without intimal neovascularization

scientific article published on 14 May 2015

Oral treatment with nicorandil at discharge is associated with reduced mortality after acute myocardial infarction

Overexpression of Nd1, a novel Kelch family protein, in the heart of transgenic mice protects against doxorubicin-induced cardiomyopathy

scientific article published on 2 September 2006

Overexpression of P104L mutant caveolin-3 in mice develops hypertrophic cardiomyopathy with enhanced contractility in association with increased endothelial nitric oxide synthase activity

scientific article published on 25 November 2003

Overexpression of TNNI3K, a cardiac-specific MAP kinase, promotes P19CL6-derived cardiac myogenesis and prevents myocardial infarction-induced injury

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Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase

scientific article published on May 2004

Oxidative stress-induced signal transduction pathways in cardiac myocytes: involvement of ROS in heart diseases

scientific article published on December 2003

PDK1 coordinates survival pathways and beta-adrenergic response in the heart

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PPARs and heart diseases

scientific article published in April 2005

Partial myocardial fibrosis in hypertrophic cardiomyopathy demonstrated by 18F-fluoro-deoxyglucose positron emission tomography and multislice computed tomography

scientific article published in February 2006

Patency of gastroepiploic arterial graft to left circumflex branch with distal portion of the anastomotic site demonstrated by multislice computed tomography

scientific article published in February 2006

Patency of the left coronary artery by 64-slice multislice computed tomography following implantation of sirolimus-eluting stent

scientific article published on 10 March 2006

Pathophysiology and therapeutic potential of cardiac fibrosis

scientific article published on 17 July 2017

Pathophysiology of myocardial reperfusion injury: preconditioning, postconditioning, and translational aspects of protective measures

scientific article published on 19 August 2011

Periodontitis and myocardial hypertrophy

scientific article published on 10 November 2016

Periodontitis deteriorates peripheral arterial disease in Japanese population via enhanced systemic inflammation

scientific article published on 31 May 2017

Periodontitis in cardiovascular disease patients with or without Marfan syndrome--a possible role of Prevotella intermedia

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Periostin Isoforms and Cardiac Remodeling After Myocardial Infarction: Is the Dispute Settled?

scientific article published in February 2016

Peroxisome proliferator-activated receptor gamma and cardiovascular diseases

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Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo

scientific article published in March 2002

Pharmacological therapeutics based on molecular mechanisms

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Phenotypic differences in aortic stenosis according to calcification grade

scientific article published on 26 April 2016

Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling

scientific article published on 30 June 2005

Pioglitazone Reduces Vascular Lipid Accumulation in Angiotensin II-Induced Hypertensive Rat.

scientific article published on 3 July 2015

Pioglitazone induces regression of coronary atherosclerotic plaques in patients with type 2 diabetes mellitus or impaired glucose tolerance: a randomized prospective study using intravascular ultrasound

scientific article published on 24 September 2008

Pioglitazone, a peroxisome proliferator-activated receptor gamma activator, ameliorates experimental autoimmune myocarditis by modulating Th1/Th2 balance

scientific article published on 20 January 2005

Pirfenidone exhibits cardioprotective effects by regulating myocardial fibrosis and vascular permeability in pressure-overloaded hearts

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Plasma low-density lipoprotein reduction and structural effects on coronary atherosclerotic plaques by atorvastatin as clinically assessed with intravascular ultrasound radio-frequency signal analysis: a randomized prospective study

scientific article published in August 2005

Platelet-derived growth factor receptor-tyrosine kinase inhibitor, imatinib, is effective for treating pulmonary hypertension induced by pulmonary tumor thrombotic microangiopathy

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Pleiotropic Effects of Angiotensin II Receptor Signaling in Cardiovascular Homeostasis and Aging

scientific article published on 27 April 2015

Pleiotropic actions of PPAR gamma activators thiazolidinediones in cardiovascular diseases

scientific article published in January 2004

Pleiotropic effects of cytokines on acute myocardial infarction: G-CSF as a novel therapy for acute myocardial infarction

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Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease

scientific article published on 05 October 2020

Porphyromonas gingivalis promotes neointimal formation after arterial injury through toll-like receptor 2 signaling

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Porphyromonas gingivalis, a periodontal pathogen, enhances myocardial vulnerability, thereby promoting post-infarct cardiac rupture

scientific article published on 11 April 2016

Prediction of the response to beta-blocker therapy in patients with dilated cardiomyopathy: comparison of 123I-MIBG scintigraphy and low-dose dobutamine stress echocardiography

scientific article published on 11 September 2009

Predictive indicators of deep venous thrombosis and pulmonary arterial thromboembolism in 54 subjects after total knee arthroplasty using multislice computed tomography in logistic regression models

scientific article published on 12 October 2006

Predictors of mortality after emergency or elective repair of abdominal aortic aneurysm in a Japanese population

scientific article published on December 30, 2012

Predictors of non-calcified plaques in the coronary arteries of 242 subjects using multislice computed tomography and logistic regression models

scientific article published on 21 July 2006

Preferential involvement of Na⁺/Ca²⁺ exchanger type-1 in the brain damage caused by transient focal cerebral ischemia in mice

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Prescription Rates of Guideline-Directed Medications Are Associated With In-Hospital Mortality Among Japanese Patients With Acute Myocardial Infarction: A Report From JROAD - DPC Study

Presence of desaturated hemoglobin enhances the contribution of blood cells to flow-mediated dilation in subjects with systemic sclerosis

scientific article published on 4 May 2013

Processed B-Type Natriuretic Peptide Is a Biomarker of Postinterventional Restenosis in Ischemic Heart Disease

scientific article published on May 13, 2013

Prognostic significance of cystatin C in patients with ST-elevation myocardial infarction.

scientific article published on 13 July 2009

Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury

scientific article published on 22 April 2010

Protective role of SIRT1 in diabetic vascular dysfunction

scientific article published on 12 March 2009

Psychometric Testing of the Japanese Version of the Self-Care of Heart Failure Index

scientific article published in August 2013

Pulmonary arterial hypertension associated with chronic active Epstein-Barr virus infection

scientific article published on 15 January 2011

Pulmonary vein morphology before and after segmental isolation in patients with atrial fibrillation

scientific article published in September 2005

Quality of coronary arterial 320-slice computed tomography images compared with 16-slice computed tomography images in subjects with chronic atrial fibrillation

scientific article published on April 6, 2011

Quality of coronary arterial 320-slice computed tomography images in subjects with chronic atrial fibrillation compared with normal sinus rhythm

scientific article published on 17 March 2010

Quantitative effect of atorvastatin on size and content of non-calcified plaques of coronary arteries 1 year after atorvastatin treatment by multislice computed tomography

scientific article published on 16 August 2007

Quantitative evaluation of chronic pulmonary thromboemboli by multislice CT compared with pulsed Tissue Doppler Imaging and its relationship with brain natriuretic peptide

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Quantitative evaluation of right atrial volume and right atrial emptying fraction by 320-slice computed tomography compared with three-dimensional echocardiography

scientific article published in January 2011

Rapid Improvement of thyroid storm-related hemodynamic collapse by aggressive anti-thyroid therapy including steroid pulse: A case report

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Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial

scientific article published on 8 March 2016

Rationale and design of a study to evaluate effects of pitavastatin on Japanese patients with chronic heart failure: the pitavastatin heart failure study (PEARL study).

scientific article published on 13 November 2010

Re-restenosis and target lesion revascularization after treatment of sirolimus-eluting stent restenosis: retrospective analysis of 4 Japanese hospitals

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Real-Time Assessment of Autonomic Nerve Activity During Adaptive Servo-Ventilation Support or Waon Therapy

scientific article published on 7 July 2016

Recent clinical management of antithrombotic agents for gastrointestinal endoscopy after revision of guidelines in Japan

scientific article published on 28 May 2015

Reduced nitric oxide causes age-associated impairment of circadian rhythmicity

scientific article published on 24 January 2008

Reduced risk of recurrent myocardial infarction in homozygous carriers of the chromosome 9p21 rs1333049 C risk allele in the contemporary percutaneous coronary intervention era: a prospective observational study

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Regeneration of the Cardiac Conduction System by Adipose Tissue-Derived Stem Cells

scientific article published on 28 September 2015

Regeneration of the endothelium as a novel therapeutic strategy for acute lung injury

scientific article published in September 2006

Relation between signal intensity on T2-weighted MR images and presence of microvascular obstruction in patients with acute myocardial infarction

scientific article published in October 2009

Relationship of natriuretic peptide and transthoracic echocardiographic findings in 135 subjects with muscular dystrophy

scientific article published on 12 January 2010

Relaxation effects of lavender aromatherapy improve coronary flow velocity reserve in healthy men evaluated by transthoracic Doppler echocardiography

scientific article published on 8 August 2007

Remarkable thickening of right atrial wall in subjects with cardiac amyloidosis complicated with sick sinus syndrome

scientific article published on 24 October 2006

Response to the letter by Devaux et al.

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Retraction: Effects of valsartan and amlodipine on cardiorenal protection in Japanese hypertensive patients: the Valsartan Amlodipine Randomized Trial

scientific article published on 3 November 2016

Retrospective ECG-gated left ventriculography using multislice CT following left ventricular bolus injection and evaluation of its utility and motion artifact at every cardiac phase

scientific article published on 18 November 2005

Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period

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Right atrium contractility and right ventricular diastolic function assessed by pulsed tissue Doppler imaging can predict brain natriuretic peptide in adults with acquired pulmonary hypertension

scientific article published on 14 September 2008

Right coronary artery aneurysm with fistula to left ventricle: multislice CT appearance

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Role of Jagged1 in arterial lesions after vascular injury

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Role of Na+-Ca2+ exchanger in myocardial ischemia/reperfusion injury: evaluation using a heterozygous Na+-Ca2+ exchanger knockout mouse model

scientific article published in February 2004

Role of heat shock transcriptional factor 1 and heat shock proteins in cardiac hypertrophy

scientific article published on April 2008

Role of telomere in endothelial dysfunction in atherosclerosis

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Role of telomeres in vascular senescence

scientific article published on January 2008

Roles of cardiac transcription factors in cardiac hypertrophy

scientific article (publication date: 30 May 2003)

Roles of peroxisome proliferator-activated receptor gamma in cardiovascular disease

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Roles of renin-angiotensin system and Wnt pathway in aging-related phenotypes

scientific article published on 9 August 2016

Roles of transient receptor potential canonical (TRPC) channels and reverse-mode Na+/Ca2+ exchanger on cell proliferation in human cardiac fibroblasts: effects of transforming growth factor β1.

scientific article published on July 2013

SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene

scientific article published on 11 March 2010

SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population

scientific article published on 25 November 2010

STAT3/Pim-1 signaling pathway plays a crucial role in endothelial differentiation of cardiac resident Sca-1+ cells both in vitro and in vivo.

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Safety and efficacy of low-dose clopidogrel in Japanese patients undergoing coronary stenting: preliminary 30-day clinical outcome

scientific article published on 2 September 2008

Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscle

scientific article published on 10 October 2004

Sarcomere gene mutations are associated with increased cardiovascular events in left ventricular hypertrophy: results from multicenter registration in Japan

scientific article published on 24 October 2013

Saturated Fatty Acid Palmitate Aggravates Neointima Formation by Promoting Smooth Muscle Phenotypic Modulation

scientific article published on August 22, 2013

Secure Combination Therapy With Low-Dose Bosentan and Ambrisentan to Treat Portopulmonary Hypertension Minimizing Each Adverse Effect

scientific article published on 18 June 2015

Serum adiponectin level is correlated with the size of HDL and LDL particles determined by high performance liquid chromatography

scientific article published on 22 June 2012

Serum apolipoprotein B-48 levels are correlated with carotid intima-media thickness in subjects with normal serum triglyceride levels

scientific article published on 18 May 2011

Serum neutrophil gelatinase-associated lipocalin concentration reflects severity of coronary artery disease in patients without heart failure and chronic kidney disease

scientific article published on 27 November 2015

Serum triglycerides predict first cardiovascular events in diabetic patients with hypercholesterolemia and retinopathy

scientific article published on 30 August 2018

Shorter Heart Failure Duration Is a Predictor of Left Ventricular Reverse Remodeling During Adaptive Servo-Ventilator Treatment in Patients With Advanced Heart Failure

scientific article published on 11 March 2016

Should cardiac resynchronization therapy be a rescue therapy for inotrope-dependent patients with advanced heart failure?

scientific article published on 27 April 2015

Significance of imbalance in the ratio of serum n-3 to n-6 polyunsaturated fatty acids in patients with acute coronary syndrome.

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Sildenafil and steroid therapy effectively improved POEMS syndrome-associated pulmonary arterial hypertension

scientific article published on December 4, 2010

Silent very late thrombotic occlusion of sirolimus-eluting stent confirmed by directional coronary atherectomy

scientific article published on 14 January 2009

Simultaneous heart rate variability monitoring enhances the predictive value of flow-mediated dilation in ischemic heart disease

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Small Molecules with Similar Structures Exhibit Agonist, Neutral Antagonist or Inverse Agonist Activity toward Angiotensin II Type 1 Receptor

scientific article published on June 14, 2012

Sonic hedgehog is a critical mediator of erythropoietin-induced cardiac protection in mice

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Sox6 regulation of cardiac myocyte development

scientific article published on October 15, 2003

Src is required for mechanical stretch-induced cardiomyocyte hypertrophy through angiotensin II type 1 receptor-dependent β-arrestin2 pathways

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Status 2 patients had poor prognosis without mechanical circulatory support

scientific article published on 03 April 2014

Stent deformity caused by coronary artery spasm

scientific article published in June 2006

Steroid-responsive thromboangiitis obliterans

scientific article published in September 2004

Stimulation of P19CL6 with multiple reagents induces pulsating particles in vivo

scientific article published on May 2005

Stretch-modulation of second messengers: effects on cardiomyocyte ion transport

scientific article published on May 1, 2003

Structural basis for potent inhibition of SIRT2 deacetylase by a macrocyclic peptide inducing dynamic structural change

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Subclinical elevation of high-sensitive troponin T levels at the convalescent stage is associated with increased 5-year mortality after ST-elevation myocardial infarction.

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Successful Conversion From Thiazide to Tolvaptan in a Patient With Stage D Heart Failure and Chronic Kidney Disease Before Heart Transplantation

scientific article published on January 1, 2013

Successful Pregnancy and Delivery in a Heart Transplantation Recipient

scientific article published on 28 April 2016

Successful bridge to recovery in fulminant myocarditis using a biventricular assist device: a case report

scientific article published on 24 October 2017

Successful treatment of hemodynamic compromise caused by antibody-mediated and cellular rejection in a recipient 12 years after heart transplantation

scientific article published in January 2013

Suitable solutions for reconstituting the ultrasound contrast agent "Levovist" used in contrast echocardiogram: in vitro and in vivo evaluation of the influence of osmotic pressure

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Superiority of synchrony of 256-slice cone beam computed tomography for acquiring pulsating objects. Comparison with conventional multislice computed tomography

scientific article published on 18 October 2006

Swimming exercise in infancy has beneficial effect on the hearts in cardiomyopathic Syrian hamsters

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Switching from carvedilol to bisoprolol ameliorates adverse effects in heart failure patients with dizziness or hypotension

scientific article published on March 31, 2013

Takayasu arteritis and ulcerative colitis: high rate of co-occurrence and genetic overlap

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Takayasu arteritis evaluated by multi-slice computed tomography in an old man.

scientific article published on 24 August 2007

Targeted therapy is required for management of pulmonary arterial hypertension after defect closure in adult patients with atrial septal defect and associated pulmonary arterial hypertension

scientific article published on 7 January 2015

Telmisartan activates endothelial nitric oxide synthase via Ser1177 phosphorylation in vascular endothelial cells

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The Current Status of Cardiovascular Medicine in Japan - Analysis of a Large Number of Health Records From a Nationwide Claim-Based Database, JROAD-DPC.

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The Less Embraces the Greater in Detecting Multiple Coronary Artery Disease

scientific article published on December 23, 2011

The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis

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The Relationship between Vascular Function and the Autonomic Nervous System

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The Structure of a Chronic Total Occlusion and Its Safe Treatment in a Patient with Chronic Thromboembolic Pulmonary Hypertension

scientific article published on 30 September 2017

The cutting-edge of medicine; genetic diagnosis for hypertrophic cardiomyopathy: how to promote its clinical application

scientific article published in May 2013

The efficacy and long-term safety of a triple combination of 80 mg telmisartan, 5 mg amlodipine and 12.5 mg hydrochlorothiazide in Japanese patients with essential hypertension: a randomized, double-blind study with open-label extension

scientific article published on September 2016

The impact of atrial fibrillation ablation on left atrial function: association with baseline left atrial function

scientific article published on 8 December 2011

The impact of sleep deprivation on the coronary circulation

scientific article published on 8 February 2009

The metabolic syndrome and DYRK1B.

scientific article published in August 2014

The pathophysiological mechanism of cardiac development and hypertrophy, and heart failure

scientific article published in May 2003

The periodontal pathogen Aggregatibacter actinomycetemcomitans affects experimental autoimmune myocarditis in mice.

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The physiological and pathological function of Ca(2 +) -dependent cysteine protease (Calpain)

scientific article published on April 1, 2013

The progress of the study of RAAS

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The ratio of serum n-3 to n-6 polyunsaturated fatty acids is associated with diabetes mellitus in patients with prior myocardial infarction: a multicenter cross-sectional study

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The role of PPARgamma-dependent pathway in the development of cardiac hypertrophy

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The role of PPARgamma-dependent pathway in the development of cardiac hypertrophy

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The role of telomerase activation in the regulation of vascular smooth muscle cell proliferation

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The significance of the shape of the left atrial roof as a novel index for determining the electrophysiological and structural characteristics in patients with atrial fibrillation

scientific article published on March 11, 2011

The ω-3 polyunsaturated fatty acid, eicosapentaenoic acid, attenuates abdominal aortic aneurysm development via suppression of tissue remodeling

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Therapeutic Implications of PPARγin Cardiovascular Diseases

scientific article published on August 12, 2010

Therapeutic activation of signal transducer and activator of transcription 3 by interleukin-11 ameliorates cardiac fibrosis after myocardial infarction

scientific article published on 25 January 2010

Three novel BMPR2 mutations associated with advanced pulmonary arterial hypertension

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Thrombosed cystic aortic arch pseudoaneurysm demonstrated by multislice computed tomography

scientific article published in April 2006

Thyroid Function Influences Serum Apolipoprotein B-48 Levels in Patients with Thyroid Disease

scientific article published on July 4, 2012

Time series of volumetric measurement of porcine three dimensional segmented myocardial perfusion by selective contrast injection using 256-slice cone beam computed tomography

scientific article published on 28 July 2005

Tocilizumab for the treatment of patients with refractory Takayasu arteritis.

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Toll-like receptor 4 signaling has a critical role in Porphyromonas gingivalis-accelerated neointimal formation after arterial injury in mice

scientific article published on 26 May 2016

Toll-like receptor-2 mediates adaptive cardiac hypertrophy in response to pressure overload through interleukin-1β upregulation via nuclear factor κB activation

scientific article published on 18 November 2013

Tolvaptan Prolongs Blockage of the Vasopressin Type II Receptor Over 24 Hours in Responders With Stage D Heart Failure

scientific article published on 8 January 2016

Tolvaptan Reduces Long-Term Total Medical Expenses and Length of Stay in Aquaporin-Defined Responders

scientific article published on 13 September 2016

Tolvaptan can improve clinical course in responders.

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Toward in vivo imaging of heart disease using a radiolabeled single-chain Fv fragment targeting tenascin-C.

scientific article published on 10 November 2011

Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice

scientific article published on 13 July 2009

Trend of clinical outcome and surrogate markers during titration of β-blocker in heart failure patients with reduced ejection fraction: relevance of achieved heart rate and β-blocker dose

scientific article published on 19 December 2012

Trends in Antidiabetic Prescription Patterns in Japan From 2005 to 2011

scientific article published on January 1, 2013

Tricolored "tricolore" myocardium by selective intracoronary injection of contrast using 256-slice cone-beam computed tomography

scientific article published on 27 February 2007

Two Susceptibility Loci to Takayasu Arteritis Reveal a Synergistic Role of the IL12B and HLA-B Regions in a Japanese Population

scientific article published on 03 July 2013

UTF1 is a chromatin-associated protein involved in ES cell differentiation

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Understanding Vascular Diseases: Lessons From Premature Aging Syndromes

scientific article published on 13 December 2015

Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy

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Urine osmolality estimated using urine urea nitrogen, sodium and creatinine can effectively predict response to tolvaptan in decompensated heart failure patients

scientific article published on 12 January 2013

Usefulness of Cardiac Iodine-123 Meta-Iodobenzylguanidine Imaging to Improve Prognostic Power of Seattle Heart Failure Model in Patients With Chronic Heart Failure

scientific article published on February 23, 2011

Usefulness of central venous saturation as a predictor of thiamine deficiency in critically ill patients: a case report

scientific article published on 6 November 2017

Usefulness of overlapping of the E and A waves of the transmitral flow as a predictor of responders to cardiac resynchronization therapy.

scientific article published on 13 March 2013

Usefulness of rapid quantitative measurement of myoglobin and troponin T in early diagnosis of acute myocardial infarction

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Usefulness of transient elastography for noninvasive and reliable estimation of right-sided filling pressure in heart failure

scientific article published on 7 November 2013

Utility of 256-slice cone beam tomography for real four-dimensional volumetric analysis without electrocardiogram gated acquisition

scientific article published on 7 November 2006

Utility of Cystatin C for Estimating Glomerular Filtration Rate in Patients With Muscular Dystrophy

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Utility of four-dimensional analysis of the acetabular labrum applying motion-gated multislice computed tomography: comparison with arthroscopy and harris hip score

scientific article published in November 2006

Utility of multislice computed tomography with a 64-data acquisition system for four-dimensional volumetric analysis using a pulsating phantom and considering pulsation rate and reconstruction methods

scientific article published on 20 August 2007

Utility of triple channel injection of contrast material with mixture of saline, with acquisition in the cephalic direction for arterial trees in the thorax using multislice computed tomography

scientific article published on 10 November 2005

VEGF-A induces its negative regulator, soluble form of VEGFR-1, by modulating its alternative splicing

scientific article published on 24 May 2013

Valsartan Amlodipine Randomized Trial (VART): design, methods, and preliminary results

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Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes

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Vascular aging: insights from studies on cellular senescence, stem cell aging, and progeroid syndromes

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Vascular cell senescence and vascular aging

scientific article published on February 2004

Vascular cell senescence: contribution to atherosclerosis

scientific article published on January 2007

Vasorin, a transforming growth factor beta-binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo

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Wnt Signaling and Aging-Related Heart Disorders

scientific article published on November 26, 2010

X-box binding protein 1 regulates brain natriuretic peptide through a novel AP1/CRE-like element in cardiomyocytes

scientific article published on 17 February 2010

[Heart failure].

scientific article

[Phospholamban].

scientific article published in April 2007

p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure

scientific article published on January 2012

p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

scientific article published in Nature