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List of works by Guro Valen

A dose-response study of glutamate supplementation in isolated, perfused rat hearts undergoing ischaemia and cold cardioplegia

scientific article

A model of neointima formation in the atherosclerotic carotid artery of mice

scientific article published on 01 June 2003

A novel glutamate transporter blocker, LL-TBOA, attenuates ischaemic injury in the isolated, perfused rat heart despite low transporter levels

scientific article published on 6 October 2013

A role for NLRP3 inflammasome in acute myocardial ischaemia-reperfusion injury? Reply ⬇️

scientific article published on May 25, 2013

ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques

scientific article (publication date: February 2008)

Activation of Liver X receptors in the heart leads to accumulation of intracellular lipids and attenuation of ischemia-reperfusion injury.

scientific article

Activity of histamine metabolizing and catabolizing enzymes during reperfusion of isolated, globally ischemic rat hearts

scientific article published on 01 March 1996

Adenosine A receptors are necessary for protection of the murine heart by remote, delayed adaptation to ischaemia

scientific article published in October 2004

Adenosine increases LPS-induced nuclear factor kappa B activation in smooth muscle cells via an intracellular mechanism and modulates it via actions on adenosine receptors

scientific article published on 28 October 2013

Apoptosis and angiogenesis are induced in the unstable coronary atherosclerotic plaque

scientific article published on 01 May 2005

Aquaporin-1 in cardiac endothelial cells is downregulated in ischemia, hypoxia and cardioplegia

scientific journal article

Aquaporin-4 in the heart: expression, regulation and functional role in ischemia

scientific article published on 10 July 2012

Can reactive oxygen species precondition the isolated rat heart against arrhythmias and stunning? ⬇️

scientific article published on 01 November 1997

Cardiac aquaporins

scientific article published on 25 October 2013

Cardiac release of histamine after ventricular fibrillation and defibrillation during insertion of implantable cardioverter defibrillators (ICD)

scientific article published on 01 November 1995

Cardiac troponin T content in heart and skeletal muscle and in blood samples from ApoE/LDL receptor double knockout mice

scientific article published in June 2004

Cardioprotection by breathing hyperoxic gas-relation to oxygen concentration and exposure time in rats and mice

scientific article published in June 2002

Cardioprotection by hypoxia-inducible factor 1 alpha transfection in skeletal muscle is dependent on haem oxygenase activity in mice

scientific article

Caught in the act: in vivo molecular imaging of the transcription factor NF-kappaB after myocardial infarction

scientific article published on 17 February 2006

Cecal ligation and puncture sepsis is associated with attenuated expression of adenylyl cyclase 9 and increased miR142-3p

scientific article published in October 2011

Cloning and functional studies of a splice variant of CYP26B1 expressed in vascular cells

scientific article

Connective tissue growth factor and bone morphogenetic protein 2 are induced following myocardial ischemia in mice and humans

scientific article published on 2 May 2017

Connective tissue growth factor/CCN2 attenuates β-adrenergic receptor responsiveness and cardiotoxicity by induction of G protein-coupled receptor kinase-5 in cardiomyocytes

scientific article published on 18 June 2013

Consequences of eliminating adenosine A1receptors in mice

Could treatment with scavengers of oxygen free radicals minimize complications in cardiac surgery? ⬇️

scientific article published on December 15, 1991

Cyclic fluctuations in the cardiac performance of the isolated Langendorff-perfused mouse heart: pyruvate abolishes the fluctuations and has an anti-ischaemic effect

scientific article published in August 2002

Deficiency of nitric oxide synthase 2 results in increased neointima formation in a mouse model of vascular injury.

scientific article published in June 2003

Does hypothermia or hyperkalemia influence the preconditioning response?

scientific article published on 01 January 1999

Effects of a Novel, Low-Molecular Weight Inhibitor of Lipid Peroxidation on Ischemia–Reperfusion Injury in Isolated Rat Hearts and in Cultured Cardiomyocytes ⬇️

scientific article published on June 1, 1998

Effects of a novel low-molecular weight antioxidant on cardiac injury induced by hydrogen peroxide.

scientific article published in January 1996

Effects of cardiac surgery on some clinically used inflammation markers and procalcitonin

scientific article

Effects of sex, gonadectomy, and oestrogen substitution on ischaemic preconditioning and ischaemia-reperfusion injury in mice

scientific article published in April 2003

Effects of spontaneous or induced brain ischemia on vessel reactivity: the role of inducible nitric oxide synthase

scientific article

Endothelial dysfunction in atherosclerotic mice: improved relaxation by combined supplementation with L-arginine-tetrahydrobiopterin and enhanced vasoconstriction by endothelin

scientific article published on December 2000

Endothelin release at reperfusion of the porcine ischaemic heart in relation to noradrenaline and neuropeptide Y

scientific article published on 01 August 1994

Exposure of rats to hyperoxia enhances relaxation of isolated aortic rings and reduces infarct size of isolated hearts

scientific article published in August 2002

Expression of bone morphogenetic protein 4 and its receptors in the remodeling heart

scientific article published on 04 January 2014

Expression of matrix metalloproteinase 9 and its regulators in the unstable coronary atherosclerotic plaque

scientific article published on 01 January 2005

Expression of retinoic acid target genes in coronary artery disease

scientific article published on 13 January 2014

Extracellular mtDNA activates NF-κB via toll-like receptor 9 and induces cell death in cardiomyocytes.

scientific article

Fibrinolysis during cardiac surgery. Release of tissue plasminogen activator in arterial and coronary sinus blood

scientific article published on 01 January 1994

Gene deletion of NF-kappaB p105 enhances neointima formation in a mouse model of carotid artery injury.

scientific article

Gene expression of inflammatory mediators in different chambers of the human heart

scientific article published on 01 August 2000

Gene therapy with hypoxia-inducible factor 1 alpha in skeletal muscle is cardioprotective in vivo

scientific article published on 14 January 2011

Glucocorticoid pretreatment protects cardiac function and induces cardiac heat shock protein 72.

scientific article

Heme oxygenase-1: an emerging therapeutic target to curb cardiac pathology

scientific article

Higher TNFα responses in young males compared to females are associated with attenuation of monocyte adenylyl cyclase expression

scientific article published on 7 May 2015

Histamine release and its effects in ischaemia-reperfusion injury of the isolated rat heart

scientific article published on 01 April 1994

Human adaptation to ischemia by preconditioning or unstable angina: involvement of nuclear factor kappa B, but not hypoxia-inducible factor 1 alpha in the heart.

scientific article

Hydrogen peroxide induces endothelial cell atypia and cytoskeleton depolymerization

scientific article published on 01 June 1999

Hydrogen peroxide induces mRNA for tumour necrosis factor alpha in human endothelial cells

scientific article

Hyperoxia elicits myocardial protection through a nuclear factor kappaB-dependent mechanism in the rat heart

scientific article published in March 2003

Importance of preanalytical handling of samples for measurement of cardiac troponin T in coronary effluent from isolated rat hearts

scientific article published in January 2002

In vivo remote delivery of DNA encoding for hypoxia-inducible factor 1 alpha reduces myocardial infarct size

scientific article published on February 2009

Increased circulating mitochondrial DNA after myocardial infarction

scientific article published on 10 May 2012

Increased expression of monocarboxylate transporter 1 after acute ischemia of isolated, perfused mouse hearts.

scientific article

Induction of inflammatory mediators during reperfusion of the human heart.

scientific article

Inhibiting nucleolin reduces inflammation induced by mitochondrial DNA in cardiomyocytes exposed to hypoxia and reoxygenation

scientific article published on 27 October 2019

Inhibition of lipoxygenase and cyclooxygenase augments cardiac injury by H2O2

scientific article published on 01 July 1993

Interleukin-17 (IL-17) expression is reduced during acute myocardial infarction: role on chemokine receptor expression in monocytes and their in vitro chemotaxis towards chemokines

scientific article

Intraperitoneal injection induces a delayed preconditioning-like effect in mice

scientific article published in July 2005

Ischaemia-reperfusion and toxic oxygen metabolites do not induce release of immunoreactive atrial natriuretic factor from isolated rat hearts

scientific article published on 01 July 1993

Ischemic postconditioning: brief ischemia during reperfusion converts persistent ventricular fibrillation into regular rhythm

scientific article published on 01 June 2004

Isoflurane and other commonly used anaesthetics do not protect the isolated buffer perfused mouse heart from ischemia-reperfusion injury

scientific article published in April 2006

Lazaroid U-83836E improves tolerance to hemorrhagic shock and limb ischemia and reperfusion in rats and increases cardiac heat shock protein 72.

scientific article

Measurements of Plasma Glutaredoxin and Thioredoxin in Healthy Volunteers and During Open-Heart Surgery ⬇️

scientific article published on May 1, 1998

Mechanical conversion of post-ischaemic ventricular fibrillation: effects on function and myocyte injury in isolated rat hearts

scientific article published on 01 February 1999

Mechanical stress alters the expression of calcification-related genes in vascular interstitial and endothelial cells

scientific article published on 01 May 2019

Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemia-reperfusion injury.

scientific article

Metabolic changes induced by ischemia and cardioplegia: a study employing cardiac microdialysis in pigs

scientific article published in January 2004

Mitochondrial DNA damage and repair during ischemia-reperfusion injury of the heart

scientific article

Myocardial protection by remote preconditioning: the role of nuclear factor kappa-B p105 and inducible nitric oxide synthase.

scientific article published in November 2004

Myocardial protection evoked by hyperoxic exposure involves signaling through nitric oxide and mitogen activated protein kinases

scientific article published on 02 February 2007

Nitric oxide mediates protective effect of endothelin receptor antagonism during myocardial ischemia and reperfusion

scientific article published on 23 December 2003

Open heart surgery increases the levels of histamine in arterial and coronary sinus blood.

scientific article published in March 1994

Oral pre-treatment with rosuvastatin protects porcine myocardium from ischaemia/reperfusion injury via a mechanism related to nitric oxide but not to serum cholesterol level.

scientific article

Oxidative stress and release of tissue plasminogen activator in isolated rat hearts

scientific article published on 01 February 1997

Pathophysiology and mediators of ischemia-reperfusion injury with special reference to cardiac surgery. A review.

scientific article published on January 1993

Perfusing isolated rat hearts with hydrogen peroxide: an experimental model of cardiac dysfunction caused by reactive oxygen species

scientific article published on August 1996

Post-ischaemic dysfunction does not correlate with release of cardiac troponin T in isolated rat hearts

scientific article published on 01 September 1999

Postconditioning in rats and mice

scientific article published on 01 December 2006

Pre- and postconditioning during cardiac surgery

scientific article

Preconditioning and cardiac surgery

scientific article

Preconditioning effects of steroids and hyperoxia on cardiac ischemia-reperfusion injury and vascular reactivity

scientific article published on 24 January 2008

Preconditioning improves cardiac function after global ischemia, but not after cold cardioplegia.

scientific article

Preconditioning protects the severely atherosclerotic mouse heart.

scientific article published in April 2001

Preconditioning the globally ischaemic, isolated rat heart: the impact of the preconditioning model on post-ischaemic systolic and diastolic function ⬇️

scientific article published on 01 November 1997

Preconditioning with hydrogen peroxide (H2O2) or ischemia in H2O2-induced cardiac dysfunction

scientific article published on 01 September 1998

Preoperative unstable angina causes venous adaptation to surgical graft injury.

scientific article published on 2 February 2007

Pretreating rats with hyperoxia attenuates ischemia-reperfusion injury of the heart

scientific article

Pretreatment with methylprednisolone protects the isolated rat heart against ischaemic and oxidative damage

scientific article published on 01 July 2000

Protecting the heart through delivering DNA encoding for heme oxygenase-1 into skeletal muscle

scientific article published on 17 August 2012

Reactive oxygen intermediates and ischemia-reperfusion injury release tissue plasminogen activator from isolated rat hearts

scientific article published on 01 July 1993

Release of Mitochondrial and Nuclear DNA During On-Pump Heart Surgery: Kinetics and Relation to Extracellular Vesicles

scientific article published on 12 December 2018

Release of creatine kinase, troponin-T, and tissue plasminogen activator in arterial and coronary venous blood during coronary artery bypass surgery

scientific article published on 01 February 1997

Release of histamine from isolated rat hearts during reperfusion is not dependent on length of ischemic insult, or contents of histamine in cardiac tissue

scientific article published on 01 September 1993

Release of markers of myocardial and endothelial injury following cold cardioplegic arrest in pigs

scientific article published on 01 January 1997

Release of tissue plasminogen activator during reperfusion after different times of ischaemia in isolated, perfused rat hearts

scientific article

Release of von Willebrand factor by cardiopulmonary bypass, but not by cardioplegia in open heart surgery

scientific article published on 01 January 1994

Retinoic acid signalling is activated in the postischemic heart and may influence remodelling

scientific article

Role of tumor necrosis factor alpha and its receptor I in preconditioning by hyperoxia

scientific article published on 22 December 2004

Sex differences in mouse heart rate and body temperature and in their regulation by adenosine A1 receptors

scientific article published in May 2007

Small skin burn injury reduces cardiac tolerance to ischemia via a tumor necrosis factor alpha-dependent pathway

scientific article published on 30 April 2007

Spontaneous ischemic events in the brain and heart adapt the hearts of severely atherosclerotic mice to ischemia

scientific article

Surgical handling of saphenous vein grafts induces expression of matrix metalloproteinase 9

scientific article published on 01 October 2008

Systemic release of thrombomodulin, but not from the cardioplegic, reperfused heart during open heart surgery

scientific article published on 01 August 1996

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury ⬇️

scientific article published on April 10, 2013

The cellular prion protein counteracts cardiac oxidative stress

scientific article

The effect of a low molecular weight inhibitor of lipid peroxidation on ultrastructural alterations to ischemia-reperfusion in the isolated rat heart

scientific article published in January 2001

The effect of exogenous adenosine on functional injury caused by hydrogen peroxide in the isolated rat heart

scientific article published on 01 January 1996

The effects of exogenous histamine in isolated rat hearts ⬇️

scientific article published on May 10, 1995

The p66ShcA adaptor protein regulates healing after myocardial infarction.

scientific article published on 14 February 2015

The role of neuronal nitric oxide synthase in ischaemia-reperfusion injury of the isolated mouse heart

scientific article published on 01 August 2001

The role of nitric oxide in ischaemia/reperfusion injury of isolated hearts from severely atherosclerotic mice.

scientific article

The role of nitric oxide in the cardiac effects of hydrogen peroxide

scientific article published in June 1996

Toxic oxygen metabolites and ischemia-reperfusion increase histamine synthesis and release in the isolated rat heart

scientific article published on 01 January 1993

Toxic oxygen metabolites and leukocytes in reperfusion injury. A review.

scientific article published on January 1993

Transient hyperosmolality modulates expression of cardiac aquaporins

scientific article published on 20 July 2012

Unstable angina activates myocardial heat shock protein 72, endothelial nitric oxide synthase, and transcription factors NFkappaB and AP-1.

scientific article

Vein graft harvesting induces inflammation and impairs vessel reactivity.

scientific article

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