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List of works by Kjetil Taskén

1,25-dihydroxyvitamin D3 alters the effect of cAMP in thyroid cells by increasing the regulatory subunit type II beta of the cAMP-dependent protein kinase

scientific article

16 Structure, function, and regulation of human cAMP-dependent protein kinases

A Cell-Based High-Throughput Assay for Gap Junction Communication Suitable for Assessing Connexin 43–Ezrin Interaction Disruptors Using IncuCyte ZOOM

scholarly article published 26 September 2016

A PKA-ezrin-Cx43 signaling complex controls gap junction communication and thereby trophoblast cell fusion

scientific article published on 22 July 2014

A fast and sensitive method for isolation of detergent-resistant membranes from T cells

scientific article published on 21 July 2005

A human whole blood model of LPS-mediated suppression of T cell activation

scientific article published in March 2003

A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system

scientific article (publication date: 28 March 2003)

A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties.

scientific article

A novel isoform of human cyclic 3',5'-adenosine monophosphate-dependent protein kinase, c alpha-s, localizes to sperm midpiece

scientific article

A phenotypic screening approach to identify anticancer compounds derived from marine fungi

scientific article

A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells

scientific article published on 7 January 2017

A soluble LAT deletion mutant inhibits T-cell activation: reduced recruitment of signalling molecules to glycolipid-enriched microdomains

scientific article

A winged helix forkhead (FOXD2) tunes sensitivity to cAMP in T lymphocytes through regulation of cAMP-dependent protein kinase RIalpha

scientific article

AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum

scientific journal article

Activated platelets promote increased monocyte expression of CXCR5 through prostaglandin E2-related mechanisms and enhance the anti-inflammatory effects of CXCL13.

scientific article published on 31 March 2014

Activated regulatory and memory T-cells accumulate in malignant ascites from ovarian carcinoma patients

scientific article published on 22 November 2014

Activation of C-terminal Src kinase (Csk) by phosphorylation at serine-364 depends on the Csk-Src homology 3 domain

scientific article

Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor

scientific article

Additive effects of IL-2 and protein kinase A type I antagonist on function of T cells from HIV-infected patients on HAART.

scientific article published in December 1999

Aggressive treatment of patients with metastatic colorectal cancer increases survival: a scandinavian single-center experience

scientific article published on 6 June 2013

Alloreactive lymphokine-activated killer cells from athymic nude rats do not express CD3-associated alpha/beta or gamma/delta T cell receptors.

scientific article

An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria

scientific journal article

An exploratory trial of cyclooxygenase type 2 inhibitor in HIV-1 infection: downregulated immune activation and improved T cell-dependent vaccine responses

scientific article

Analysing phosphorylation-based signalling networks by phospho flow cytometry

scientific article published on 16 July 2010

Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding

scientific article (publication date: 28 April 2000)

Anchored PKA as a gatekeeper for gap junctions

scientific article published on July 2015

Aspirin As Secondary Prevention in Patients With Colorectal Cancer: An Unselected Population-Based Study

scientific article published on 31 May 2016

Assignment of the gene encoding the 5-HT1E serotonin receptor (S31) (locus HTR1E) to human chromosome 6q14-q15

scientific article (publication date: August 1994)

Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

scientific article

Autologous bone marrow Th cells can support multiple myeloma cell proliferation in vitro and in xenografted mice.

scientific article published on 24 February 2017

Binding of PKA-RIIalpha to the Adenovirus E1A12S oncoprotein correlates with its nuclear translocation and an increase in PKA-dependent promoter activity

scientific article published in June 2001

C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease

scientific article published on 31 July 2017

CD147 (Basigin/Emmprin) identifies FoxP3+CD45RO+CTLA4+-activated human regulatory T cells

CD147 in regulatory T cells

scientific article published on March 2013

CD7 is a differentiation marker that identifies multiple CD8 T cell effector subsets

scientific article

CD8+ T Cells That Coexpress RORγt and T-bet Are Functionally Impaired and Expand in Patients with Distal Bile Duct Cancer.

scientific article published on 4 January 2017

CD8+ regulatory T cells-A distinct T-cell lineage or a transient T-cell phenotype?

scientific article published on 24 September 2008

CDK1-mediated phosphorylation of the RIIalpha regulatory subunit of PKA works as a molecular switch that promotes dissociation of RIIalpha from centrosomes at mitosis.

scientific article

CREB phosphorylation and melatonin biosynthesis in the rat pineal gland: Involvement of cyclic AMP dependent protein kinase type II

scientific article published on 01 October 1999

Cancer Immunity and Immune Evasion Mechanisms

Carboxyl-Terminal Src Kinase Binds CD28 upon Activation and Mutes Downstream Signaling

scientific article published on 10 July 2019

Cell signalling analyses in the functional genomics era.

scientific article published on 28 January 2013

Characterization of A-kinase-anchoring disruptors using a solution-based assay

scientific article

Characterization of in-vitro-translated human regulatory and catalytic subunits of cAMP-dependent protein kinases

scientific article published on 01 February 1994

Characterization of the 5'-flanking region of the gene for the cAMP-inducible protein kinase A subunit, RIIbeta, in Sertoli cells

scientific article published on April 1997

Characterization of the human gene encoding the type I alpha and type I beta cGMP-dependent protein kinase (PRKG1).

scientific article

ChemInform Abstract: Stereoselective Synthesis of (RP)-8-Substituted-N6-acylated and N6-Alkylated Adenosine-3′,5′-cyclic Phosphorothioic Acids as cAMP Antagonists

Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450

scientific article

Combined Env- and Gag-specific T cell responses in relation to programmed death-1 receptor and CD4 T cell loss rates in human immunodeficiency virus-1 infection

scientific article published on 10 May 2010

Combined spatial and enzymatic regulation of Csk by cAMP and protein kinase a inhibits T cell receptor signaling

scientific article published on 28 March 2003

Compartmentalization of cAMP signaling in adipogenesis, lipogenesis, and lipolysis.

scientific article published on 23 September 2014

Correction: Inhibition of T Cell Activation by Cyclic Adenosine 5'-Monophosphate Requires Lipid Raft Targeting of Protein Kinase A Type I by the A-Kinase Anchoring Protein Ezrin

Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia.

scientific article

Coupled motions in the SH2 and kinase domains of Csk control Src phosphorylation

scientific article published in August 2005

Creating order from chaos: cellular regulation by kinase anchoring

scientific article published on 8 October 2012

Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans.

scientific article published on 20 April 2016

Cross talk between phosphatidylinositol 3-kinase and cyclic AMP (cAMP)-protein kinase a signaling pathways at the level of a protein kinase B/beta-arrestin/cAMP phosphodiesterase 4 complex

scientific article published on 19 January 2010

Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase

scientific article (publication date: September 1999)

Cryopreservation of primary B cells minimally influences their signaling responses

scientific article published in Scientific Reports

Crystal structure of the central domain of human AKAP18 gamma/delta in complex with malonate

Csk

Csk binding protein

Cyclic AMP Sensitive Signalling by the CD28 Marker Requires Concomitant Stimulation by the T-Cell Antigen Receptor (TCR/CD3) Complex

scientific article published on 01 August 1994

Cyclic AMP downregulates c-myc expression by inhibition of transcript initiation in human B-precursor Reh cells

scientific article published on January 1994

Cyclic AMP-dependent protein kinase (cAK) in human B cells: co-localization of type I cAK (RI alpha 2 C2) with the antigen receptor during anti-immunoglobulin-induced B cell activation

scientific article

Cyclic AMP-dependent protein kinases and human trophoblast cell differentiation in vitro ⬇️

scientific article published on 01 April 1998

Cyclic AMP-mediated immune regulation--overview of mechanisms of action in T cells

scientific article published on 02 December 2010

Cyclic-AMP-dependent protein kinase (PKA) in testicular cells. Cell specific expression, differential regulation and targeting of subunits of PKA

scientific article published on 01 May 2000

Cyclic-AMP-dependent protein kinase (PKA) in testicular cells. Cell specific expression, differential regulation and targeting of subunits of PKA.

scientific article

Cyclo-oxygenase type 2-dependent prostaglandin E2 secretion is involved in retrovirus-induced T-cell dysfunction in mice.

scientific article published on December 2004

Cytokine networks are pre-activated in T cells from HIV-infected patients on HAART and are under the control of cAMP.

scientific article published in January 2004

Cytokine profile of CD4+ T-cells in decidua and circulation in 3rd trimester pregnancy

Defective IL-4 signaling in T cells defines severe common variable immunodeficiency

scientific article published on 2 May 2017

Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptor

scientific article published on 25 May 2006

Design of proteolytically stable RI-anchoring disruptor peptidomimetics for in vivo studies of anchored type I protein kinase A-mediated signalling.

scientific article

Diastolic dysfunction in alveolar hypoxia: a role for interleukin-18-mediated increase in protein phosphatase 2A.

scientific article published on 3 July 2008

Different Mechanisms are Involved in cAMP-Mediated Induction of mRNAs for Subunits of cAMP-Dependent Protein Kinases

article by Kristin Austlid Taskén et al published January 1991 in Molecular Endocrinology

Differential localization of protein kinase A type II isozymes in the Golgi-centrosomal area

scientific article published on May 1999

Differentiation of naive CD4+ T cells into CD4+CD25+FOXP3+ regulatory T cells by continuous antigen stimulation.

scientific article published on 12 February 2008

Dissociating the centrosomal matrix protein AKAP450 from centrioles impairs centriole duplication and cell cycle progression

scientific article

Distinct but overlapping domains of AKAP95 are implicated in chromosome condensation and condensin targeting

scientific article

Dual specificity A-kinase anchoring proteins (AKAPs) contain an additional binding region that enhances targeting of protein kinase A type I.

scientific article published on 29 September 2008

EGF signalling and rapamycin-mediated mTOR inhibition in glioblastoma multiforme evaluated by phospho-specific flow cytometry

scientific article

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

scientific article published on 07 January 2019

Effect of activated platelets on expression of cytokines in peripheral blood mononuclear cells - potential role of prostaglandin E2.

scientific article published in December 2004

Effects of type I protein kinase A modulation on the T cell distal pole complex.

scientific article

Elevated Expression of Lanosterol 14α-Demethylase (CYP51) and the Synthesis of Oocyte Meiosis-Activating Sterols in Postmeiotic Germ Cells of Male Rats1

Elevated expression of lanosterol 14alpha-demethylase (CYP51) and the synthesis of oocyte meiosis-activating sterols in postmeiotic germ cells of male rats

scientific article published in May 1998

Endosome-to-Golgi transport is regulated by protein kinase A type II alpha

scientific article published on 4 November 2002

Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically

scientific article published on 12 March 2022

Expression of protein kinase A and protein kinase C during ongoing human cytomegalovirus infection.

scientific article published on January 1994

Ezrin-anchored PKA phosphorylates serine 369 and 373 on connexin 43 to enhance gap junction assembly, communication, and cell fusion

scientific article published on 19 December 2017

F.106. Sequential Development of NaïVe T-Cells Into CD25+ FOXP3+ Regulatory T-Cells By Continuous Antigen Stimulation

F.131. Regulatory T-Cells in Colorectal Cancer Suppress Immune Function and Anti-Tumor Activity

FOXK1 and FOXK2 regulate aerobic glycolysis

scientific article published on 30 January 2019

FOXP3+CD4+CD25+ Adaptive Regulatory T Cells Express Cyclooxygenase-2 and Suppress Effector T Cells by a Prostaglandin E2-Dependent Mechanism

scientific article published on 01 July 2006

Forskningsmetodikk på enkeltcellenivå

Generation of highly suppressive adaptive CD8(+)CD25(+)FOXP3(+) regulatory T cells by continuous antigen stimulation

scientific article published in March 2008

Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location

scientific article

High-resolution mapping of prostaglandin E2-dependent signaling networks identifies a constitutively active PKA signaling node in CD8+CD45RO+ T cells

scientific article published on 17 June 2010

Human naturally occurring and adaptive regulatory T cells secrete high levels of leukaemia inhibitory factor upon activation

scientific article

Human regulatory T cells control TCR signaling and susceptibility to suppression in CD4+ T cells.

scientific article published on 29 December 2015

Human regulatory subunit RI beta of cAMP-dependent protein kinases: expression, holoenzyme formation and microinjection into living cells

scientific article (publication date: October 1994)

Humanized mice as a useful model to study HIV-1 induced immune activation, its mechanisms and potential therapeutic approaches.

scientific article published on 3 October 2011

Hypophosphorylated TCR/CD3zeta signals through a Grb2-SOS1-Ras pathway in Lck knockdown cells

scientific article published on September 2007

Identification and Quantitation of cAMP-dependent Protein Kinase R Subunit Isoforms in Subcellular Fractions of Failing Human Myocardium

Identification, cloning and characterization of a novel nuclear protein, HA95, homologous to A-kinase anchoring protein 95

scientific article

Immune activation and HIV-specific T cell responses are modulated by a cyclooxygenase-2 inhibitor in untreated HIV-infected individuals: An exploratory clinical trial

scientific article

Immune modulatory effects of cyclooxygenase type 2 inhibitors in HIV patients on combination antiretroviral treatment

article

Impaired secretion of IL-10 by T cells from patients with common variable immunodeficiency--involvement of protein kinase A type I.

scientific article published in June 2003

In Vivo Administration of a PKA Type I Inhibitor (Rp-8-Br-cAMPS) Restores T-Cell Responses in Retrovirus-Infected Mice

scientific article published on 18 April 2008

In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region

scientific article published on September 2005

Increased cAMP levels and protein kinase (PKA) type I activation in CD4+ T cells and B cells contribute to retrovirus-induced immunodeficiency of mice (MAIDS): a useful in vivo model for drug testing

scientific article published on 01 June 2001

Increased cAMP signaling can ameliorate the hypertensive condition in spontaneously hypertensive rats

scientific article published on 31 May 2008

Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin

scientific article

Inhibition of antigen-specific T cell proliferation and cytokine production by protein kinase A type I.

scientific article published in July 2002

Inhibition of protein kinase A improves effector function of monocytes from HIV-infected patients

scientific article published in July 2008

Insulin and TNF alpha induce expression of the forkhead transcription factor gene Foxc2 in 3T3-L1 adipocytes via PI3K and ERK 1/2-dependent pathways

scientific article

Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity.

scientific article

Interferon-gamma Stimulation of Messenger RNA for Human Secretory Component (poly-Ig Receptor) Depends on Continuous Intermediate Protein Synthesis

scientific article published on 01 February 1993

Interleukin-10-secreting T cells define a suppressive subset within the HIV-1-specific T-cell population.

scientific article published on May 2009

Interleukin-33 drives a proinflammatory endothelial activation that selectively targets nonquiescent cells.

scientific article

Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation

scientific article

Is basic endocrinology disappearing?

scientific article published on 01 January 1996

Isoform-specific regulation of the CCAAT/enhancer-binding protein family of transcription factors by 3',5'-cyclic adenosine monophosphate in Sertoli cells

scientific article

Isozymes of cyclic AMP-dependent protein kinases (PKA) in human lymphoid cell lines: levels of endogenous cAMP influence levels of PKA subunits and growth in lymphoid cell lines

scientific article published on October 1998

Kinetic properties of the C-terminal Src kinase, p50csk

scientific article published in May 1998

Kinetics and Activation Requirements of Contact-Dependent Immune Suppression by Human Regulatory T Cells

Knockdown of C-terminal Src kinase by siRNA-mediated RNA interference augments T cell receptor signaling in mature T cells

scientific article

LPS-activated monocytes suppress T-cell immune responses and induce FOXP3+ T cells through a COX-2-PGE2-dependent mechanism

scientific article published on 20 December 2007

LYP inhibits T-cell activation when dissociated from CSK.

scientific article

Localization of a novel human A-kinase-anchoring protein, hAKAP220, during spermatogenesis

scientific article (publication date: July 2000)

Localization of cAMP-dependent signal transducers in early rat liver carcinogenesis ⬇️

scientific article published on March 1, 1998

Localized effects of cAMP mediated by distinct routes of protein kinase A.

scientific article published on January 2004

Location of cAMP-dependent protein kinase type I with the TCR-CD3 complex

scientific article published in Science

Malonate in the nucleotide-binding site traps human AKAP18γ/δ in a novel conformational state

scientific article published on 13 July 2016

Mapping of the gene encoding the regulatory subunit RII alpha of cAMP-dependent protein kinase (locus PRKAR2A) to human chromosome region 3p21.3-p21.2.

scientific article

Mechanisms of FOXC2- and FOXD1-mediated regulation of the RI alpha subunit of cAMP-dependent protein kinase include release of transcriptional repression and activation by protein kinase B alpha and cAMP.

scientific article

Melatonin synthesis in the bovine pineal gland is regulated by type II cyclic AMP-dependent protein kinase

scientific article published on 01 February 1997

Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.

scientific article published in August 2003

Mice with disrupted type I protein kinase A anchoring in T cells resist retrovirus-induced immunodeficiency

scientific article published on 23 March 2011

Mitosis-specific Phosphorylation and Subcellular Redistribution of the RIIα Regulatory Subunit of cAMP-dependent Protein Kinase

scientific article published in Journal of Biological Chemistry

Modulation of Secretory Lysosomes During NK Cell Education Leads to Accumulation of Granzyme B and Enhanced Functional Potential

Modulation of T cell immune functions by the prostaglandin E2 – cAMP pathway in chronic inflammatory states ⬇️

scientific article published on May 1, 2012

Modulation of proximal signaling in normal and transformed B cells by transmembrane adapter Cbp/PAG.

scientific article

Molecular Basis of AKAP Specificity for PKA Regulatory Subunits

Molecular Basis of AKAP Specificity for PKA Regulatory Subunits

Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling Units

scientific article

Molecular architecture of signal complexes regulating immune cell function

scientific article published on January 2008

Molecular cloning and cell-specific expression of newly discovered subunits of cAMP-dependent protein kinases. Implications for different cellular responses to cAMP

article

Molecular cloning and exon-intron mapping of the gene encoding human transmembrane secretory component (the poly-Ig receptor)

scientific article (publication date: September 1992)

Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells

scientific article

Molecular cloning, cDNA structure and deduced amino acid sequence for a type I regulatory subunit of cAMP-dependent protein kinase from human testis

scientific journal article

Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases

scientific article

Molecular cloning, cDNA structure, and chromosomal localization of the human type II cGMP-dependent protein kinase

scientific article

Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95

scientific article

Molecular cloning, complementary deoxyribonucleic acid structure and predicted full-length amino acid sequence of the hormone-inducible regulatory subunit of 3'-5'-cyclic adenosine monophosphate-dependent protein kinase from human testis

scientific article

Molecular cloning, upstream sequence and promoter studies of the human gene for the regulatory subunit RII alpha of cAMP-dependent protein kinase

scientific article

Molecular mechanisms for protein kinase A-mediated modulation of immune function

scientific article

Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry

scientific article published on 28 June 2015

Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network

scientific article published on 12 December 2008

Negative regulation of T-cell receptor activation by the cAMP-PKA-Csk signalling pathway in T-cell lipid rafts

scientific article

Novel alternatively spliced mRNA (1c) of the protein kinase A RIα subunit is implicated in haploid germ cell specific expression

scientific article published on 01 May 2001

Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes

scientific article

Novel mechanism of signaling by CD28.

scientific article published on February 2010

OPA1 in Lipid Metabolism: Function of OPA1 in Lipolysis and Thermogenesis of Adipocytes

scientific article published on 20 April 2017

OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells.

scientific article published on 24 April 2018

Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis

scientific article published on 7 October 2011

PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans

scientific article published on 15 January 2010

PKA

PKAI as a potential target for therapeutic intervention.

scientific article published in February 2000

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects

scientific article published on 04 May 2018

Phosphodiesterases as targets for modulating T-cell responses

scientific article published on January 2011

Phosphoprotein Detection by High-Throughput Flow Cytometry

scientific article published on January 2016

Physiological Substrates of PKA and PKG

article

Physiological Substrates of PKA and PKG

Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts

scientific article published on October 2016

Positive and negative regulation of T-cell activation through kinases and phosphatases

scientific article

Proinflammatory and immunoregulatory roles of eicosanoids in T cells

scientific article published on 04 June 2013

Prostaglandin E2 induces the expression of functional inhibitory CD94/NKG2A receptors in human CD8+ T lymphocytes by a cAMP-dependent protein kinase A type I pathway

scientific article published in September 2005

Protein Kinase A Intersects Src Signaling in Membrane Microdomains

scientific article published in Journal of Biological Chemistry

Protein Kinase A-anchoring Protein AKAP95 Interacts with MCM2, a Regulator of DNA Replication ⬇️

scientific article published on May 9, 2003

Protein kinase A antagonist inhibits β-catenin nuclear translocation, c-Myc and COX-2 expression and tumor promotion in Apc(Min/+) mice

scientific article

Protein kinase A type I antagonist restores immune responses of T cells from HIV-infected patients.

scientific article published in July 1998

Protein kinase C activation and positive and negative agonist regulation of 3′, 5′-cyclic adenosine monophosphate levels in cultured rat Sertoli cells ⬇️

scientific article published on 01 June 1993

Protein kinase C activation by 12-O-tetradecanoylphorbol 13-acetate modulates messenger ribonucleic acid levels for two of the regulatory subunits of 3',5'-cyclic adenosine monophosphate-dependent protein kinases (RII beta and RI alpha) via multiple ⬇️

scientific article published on March 1, 1992

Protein kinase C activation selectively increases mRNA levels for one of the regulatory subunits (RI alpha) of cAMP-dependent protein kinases in HT-29 cells

scientific article published on October 1990

Proximal signaling responses in peripheral T cells from colorectal cancer patients are affected by high concentrations of circulating prostaglandin E2.

scientific article

Quantitative profiling of tyrosine phosphorylation revealed changes in the activity of the T cell receptor signaling pathway upon cisplatin-induced apoptosis

scientific article published on 7 August 2013

Quantitative proteome analysis of detergent-resistant membranes identifies the differential regulation of protein kinase C isoforms in apoptotic T cells

Reciprocal regulation of SH3 and SH2 domain binding via tyrosine phosphorylation of a common site in CD3epsilon

scientific article

Reciprocal regulation of mRNA and protein for subunits of cAMP-dependent protein kinase (RI alpha and C alpha) by cAMP in a neoplastic B cell line (Reh).

scientific article published on November 1993

Reduced Cbl phosphorylation and degradation of the zeta-chain of the T-cell receptor/CD3 complex in T cells with low Lck levels

scientific article

Reduced PDE4 expression and activity contributes to enhanced catecholamine-induced cAMP accumulation in adipocytes from FOXC2 transgenic mice

scholarly article by Line M. Grønning published in June 2006

Regulation of FynT function by dual domain docking on PAG/Cbp

scientific article

Regulation of Glucocorticoid Receptor (GR) mRNA and protein levels by phorbol ester in MCF-7 cells. Mechanism of GR mRNA induction and decay

scientific article published on 01 January 1994

Regulation of anchoring of the RIIalpha regulatory subunit of PKA to AKAP95 by threonine phosphorylation of RIIalpha: implications for chromosome dynamics at mitosis

scientific article

Regulation of growth in a neoplastic B cell line by transfected subunits of 3',5'-cyclic adenosine monophosphate-dependent protein kinase

scientific article published on November 1994

Regulation of tissue inhibitor of metalloproteinases-1 in rat Sertoli cells: induction by germ cell residual bodies, interleukin-1alpha, and second messengers

scientific article published on April 2000

Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner

scientific article published on 26 October 2007

Regulatory T cells that co-express RORγt and FOXP3 are pro-inflammatory and immunosuppressive and expand in human pancreatic cancer

scientific article published on 29 October 2015

Regulatory T-cell-mediated inhibition of antitumor immune responses is associated with clinical outcome in patients with liver metastasis from colorectal cancer

article

Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts

scientific article

Remodeling of secretory lysosomes during education tunes functional potential in NK cells

scientific article published in Nature Communications

Reply to M. Løberg et al

Report on the 9th European Workshop on the Molecular and Cellular Endocrinology of the Testis

scientific article published on 01 August 1996

Retinoblastoma protein is rapidly dephosphorylated by elevated cyclic adenosine monophosphate levels in human B-lymphoid cells.

scientific article published on April 1994

Review: Spatiotemporal dynamics of hCG/cAMP signaling and regulation of placental function ⬇️

scientific article published on November 21, 2011

Role for the cAMP-protein kinase A signaling pathway in suppression of antitumor immune responses by regulatory T cells

scientific article published on January 2008

Role of cAMP phosphodiesterase 4 in regulation of T-cell function

scientific article published on January 2006

Role of cyclic AMP-dependent protein kinases in human villous cytotrophoblast differentiation

Selective Activation of cAMP-dependent Protein Kinase Type I Inhibits Rat Natural Killer Cell Cytotoxicity

scientific article published in Journal of Biological Chemistry

Short-interfering RNA-mediated Lck knockdown results in augmented downstream T cell responses

scientific article published on December 2005

Single cell profiling of phospho-protein levels in chronic lymphocytic leukemia.

scientific article

Spatiotemporal control of cyclic AMP immunomodulation through the PKA-Csk inhibitory pathway is achieved by anchoring to an Ezrin-EBP50-PAG scaffold in effector T cells

scientific article published on 24 April 2010

Spatiotemporal regulation of cAMP signaling controls the human trophoblast fusion

scientific article published on 15 September 2015

Specificity and spatial dynamics of protein kinase A signaling organized by A-kinase-anchoring proteins

scientific article published on 11 February 2010

Specificity in the cAMP PKA signaling pathway differential expression regulation and subcellular localization of subunits oF PKA ⬇️

scientific article published on July 1, 1997

Specificity in the cAMP/PKA signaling pathway. Differential expression,regulation, and subcellular localization of subunits of PKA.

scientific article

Spleen tyrosine kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells

scientific article published on 20 November 2015

Splicing factor arginine/serine-rich 17A (SFRS17A) is an A-kinase anchoring protein that targets protein kinase A to splicing factor compartments

scientific article

Stereoselective preparation of (RP)-8-hetaryladenosine-3′,5′-cyclic phosphorothioic acids

Stereoselective synthesis of (RP)-8-substituted-N6-acylated and N6-alkylated adenosine-3′,5′-cyclic phosphorothioic acids as cAMP antagonists ⬇️

scientific article published on 07 October 2011

Structure, function, and regulation of human cAMP-dependent protein kinases

scientific article

Su.44. IL-10-Producing HIV-Specific T Cells Have Suppressive Properties

article

Su.67. Monocytes Modulate T-Cell Immune Responses in a Pge2-Cox-2 Dependent Manner and Induce Foxp3+-Cd4+- T-Cells

article

T cell-signaling network analysis reveals distinct differences between CD28 and CD2 costimulation responses in various subsets and in the MAPK pathway between resting and activated regulatory T cells

scientific article

T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses

scientific article published in June 2014

TCR- and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling

scientific article published in October 2004

Targeting Tuberculosis and HIV Infection-Specific Regulatory T Cells with MEK/ERK Signaling Pathway Inhibitors

scientific article

Targeting of type I protein kinase A to lipid rafts is required for platelet inhibition by the 3',5'-cyclic adenosine monophosphate-signaling pathway.

scientific article

Targeting protein-protein interactions in complexes organized by A kinase anchoring proteins

scientific article

The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection

scientific article

The Human Gene for the Regulatory Subunit RIα of Cyclic Adenosine 3′,5′-Monophosphate-Dependent Protein Kinase: Two Distinct Promoters Provide Differential Regulation of Alternately Spliced Messenger Ribonucleic Acids1

article

The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function

scientific article published on 28 January 2019

The RIAD peptidomimetic inhibits HIV-1 replication in humanized NSG mice

scientific article published on 28 November 2013

The adaptor protein EBP50 is important for localization of the protein kinase A-Ezrin complex in T-cells and the immunomodulating effect of cAMP

scientific journal article

The autoimmune-predisposing variant of lymphoid tyrosine phosphatase favors T helper 1 responses.

scientific article

The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin

scientific article published on 9 August 2004

The epidermal growth factor-like growth factor amphiregulin is strongly induced by the adenosine 3',5'-monophosphate pathway in various cell types

scientific article

The gene encoding the C gamma catalytic subunit of cAMP-dependent protein kinase is a transcribed retroposon

scientific article

The gene encoding the catalytic subunit C alpha of cAMP-dependent protein kinase (locus PRKACA) localizes to human chromosome region 19p13.1

scientific article

The heterotrimeric G-protein alpha-subunit Galphaq regulates TCR-mediated immune responses through an Lck-dependent pathway

scientific article

The human gene for the regulatory subunit RI alpha of cyclic adenosine 3', 5'-monophosphate-dependent protein kinase: two distinct promoters provide differential regulation of alternately spliced messenger ribonucleic acids

scientific article published on January 1997

The potential use of AKAP18δ as a drug target in heart failure patients

Treatment with type-2 selective and non-selective cyclooxygenase inhibitors improves T-cell proliferation in HIV-infected patients on highly active antiretroviral therapy

scientific article published in April 2004

Treatment with type-2 selective and non-selective cyclooxygenase inhibitors improves T-cell proliferation in HIV-infected patients on highly active antiretroviral therapy

article

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