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List of works by John Olney

24 Excitotoxic amino acids as neuroendocrine research tools

scientific article published on January 1, 1983

A benzodiazepine recognition site associated with the non-NMDA glutamate receptor

scientific article published in January 1993

A comparative evaluation of the neurotoxic properties of ketamine and nitrous oxide

scientific article published in March 2001

A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death

scientific article

Acute behavioral effects of MK-801 in the mouse

scientific article published in March 1996

Acute elevations of serum luteinizing hormone induced by kainic acid, N-methyl aspartic acid or homocysteic acid

scientific article published on January 1, 1978

Acute glutamate-induced elevations in serum testosterone and luteinizing hormone

scientific article published on August 13, 1976

Adenylyl cyclases types 1 and 8 promote pro-survival pathways after ethanol exposure in the neonatal brain

scientific article

Age dependent sensitivity of the rat retina to the excitotoxic action of N-methyl-D-aspartate

scientific article published in June 1995

Age-related changes in glutamate concentration and synaptosomal glutamate uptake in adult rat striatum ⬇️

scientific article published on March 23, 1981

Age-related sensitivity to kainate neurotoxicity ⬇️

scientific article published on November 1, 1991

Age-specific neurotoxicity in the rat associated with NMDA receptor blockade: potential relevance to schizophrenia?

scientific article published on December 1995

Alcohol-induced apoptosis of oligodendrocytes in the fetal macaque brain

scientific article published on 12 June 2013

Alcohol-induced neuroapoptosis in the fetal macaque brain

scientific article

An ex vivo rat retinal preparation for excitotoxicity studies

scientific article published in August 1995

Anesthesia-induced developmental neuroapoptosis. Does it happen in humans?

scientific article

Anti-parkinsonian agents are phencyclidine agonists and N-methyl-aspartate antagonists

scientific article published on 01 October 1987

Anti-parkinsonian agents procyclidine and ethopropazine alleviate thermal hyperalgesia in neuropathic rats

scientific article

Antiepileptic drugs and apoptotic neurodegeneration in the developing brain

scientific article

Antipsychotic drugs block phencyclidine receptor-mediated neurotoxicity

scientific article published in July 1993

Apoptosis in the in vivo mammalian forebrain

scientific article

Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults

scientific article published in December 2004

Are glycine sites saturated In vivo?

scientific article published on 01 December 2000

Basal forebrain lesions impair tactile discrimination and working memory

scientific article published in March 1989

Behavioral consequences of NMDA antagonist-induced neuroapoptosis in the infant mouse brain

scientific article

Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology

scientific article published on August 2001

Biochemical and morphological analysis of non-NMDA receptor mediated excitotoxicity in chick embryo retina

scientific article published on 01 January 1999

Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain

scientific article published in January 1999

Blockade of both NMDA and non-NMDA receptors is required for optimal protection against ischemic neuronal degeneration in the in vivo adult mammalian retina ⬇️

scientific article published on July 1, 1991

Blockade of the second messenger functions of the glutamate metabotropic receptor is associated with degenerative changes in the retina and brain of immature rodents

scientific article published in August 1995

Brain damage in mice from voluntary ingestion of glutamate and aspartate

scientific article published on 01 January 1980

Ca2+-Independent Excitotoxic Neurodegeneration in Isolated Retina, an Intact Neural Net: A Role for Cl− and Inhibitory Transmitters ⬇️

scientific article published on 01 March 1998

Caffeine Augments Anesthesia Neurotoxicity in the Fetal Macaque Brain.

scientific article

Calcium influx accompanies but does not cause excitotoxin-induced neuronal necrosis in retina

scientific article published on April 1985

Calcium-stimulated adenylyl cyclases modulate ethanol-induced neurodegeneration in the neonatal brain.

scientific article published in March 2005

Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis.

scientific article published in February 2007

Characterization of two novel N-methyl-D-aspartate antagonists: EAA-090 (2-[8,9-dioxo-2,6-diazabicyclo [5.2.0]non-1(7)-en2-yl]ethylphosphonic acid) and EAB-318 (R-alpha-amino-5-chloro-1-(phosphonomethyl)-1H-benzimidazole-2-propanoic acid hydrochlori

scientific article

Chronic but not acute estradiol treatment protects against the neurodegenerative effects of N-methyl-D-aspartate receptor antagonists

scientific article published in June 2003

Clonidine potentiates the neuropathic pain-relieving action of MK-801 while preventing its neurotoxic and hyperactivity side effects ⬇️

scientific article published on January 19, 1998

Comparison of behavioral effects of nucleus basalis magnocellularis lesions and somatosensory cortex ablation in the rat.

scientific article

Comparison of rat retinal fixation techniques: chemical fixation and microwave irradiation

scientific article published on 01 February 2000

D-aminaphosphonovalerate is 100-fold more powerful than D-alpha-aminoadipate in blocking N-methylaspartate neurotoxicity ⬇️

scientific article published on September 21, 1981

Delayed excitotoxic neurodegeneration induced by excitatory amino acid agonists in isolated retina

scientific article published on 01 July 1995

Developmental neurotoxicity of alcohol and anesthetic drugs is augmented by co-exposure to caffeine

scientific article published on July 2013

Dimethyl sulfoxide (DMSO) produces widespread apoptosis in the developing central nervous system

scientific article

Disseminated corticolimbic neuronal degeneration induced in rat brain by MK-801: potential relevance to Alzheimer's disease

scientific article published in November 1998

Distinguishing excitotoxic from apoptotic neurodegeneration in the developing rat brain

scientific article published in June 1999

Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain

scientific article published on 01 May 1995

Do pediatric drugs cause developing neurons to commit suicide?

scientific article published on March 2004

Domoic acid: a dementia-inducing excitotoxic food poison with kainic acid receptor specificity

scientific article published in October 1990

Donepezil markedly potentiates memantine neurotoxicity in the adult rat brain

scientific article published on 16 November 2006

Drug-Induced Apoptosis: Mechanism by which Alcohol and Many Other Drugs Can Disrupt Brain Development

scientific article published on September 2013

Drug-induced apoptotic neurodegeneration in the developing brain.

scientific article

Drugs of abuse that cause developing neurons to commit suicide

scientific article

Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits

scientific article

Effect of nitrous oxide on excitatory and inhibitory synaptic transmission in hippocampal cultures

scientific article

Effects of lactate and pyruvate on glucose deprivation in rat hippocampal slices.

scientific article

Effects of morphine or naloxone on kainic acid neurotoxicity

scientific article published on May 7, 1979

Efficacy of clozapine compared with other antipsychotics in preventing NMDA-antagonist neurotoxicity.

scientific article published in September 1994

Environmental agents that have the potential to trigger massive apoptotic neurodegeneration in the developing brain

scientific article

Ethanol causes and lithium prevents neuroapoptosis and suppression of pERK in the infant mouse brain

scientific article published on 02 July 2008

Ethanol-Induced Apoptotic Neurodegeneration and Fetal Alcohol Syndrome

scientific article published in Science

Ethanol-induced apoptosis in the developing visual system during synaptogenesis

scientific article

Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain

scientific article published in February 2002

Ethanol-induced caspase-3 activation in the in vivo developing mouse brain

scientific article published in March 2002

Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures

scientific article

Excessive cerebrocortical release of acetylcholine induced by NMDA antagonists is reduced by GABAergic and alpha2-adrenergic agonists

scientific article

Excitatory transmitter neurotoxicity

scientific article published on March 1994

Excitotoxic cell death dependent on inhibitory receptor activation

scientific article published on 01 November 1999

Excitotoxic mechanisms of epileptic brain damage

scientific article published on January 1986

Excitotoxic neurodegeneration in Alzheimer disease. New hypothesis and new therapeutic strategies

scientific article

Excitotoxic neurodegeneration induced by deprivation of oxygen and glucose in isolated retina ⬇️

scientific article published on 01 February 1998

Excitotoxic neuronal damage and neuropsychiatric disorders

scientific article

Excitotoxic versus apoptotic mechanisms of neuronal cell death in perinatal hypoxia/ischemia

scientific article published on March 2004

Excitotoxicity and the NMDA receptor--still lethal after eight years

scientific article published on February 1995

Excitotoxicity in the embryonic chick spinal cord ⬇️

scientific article published on December 1, 1991

Excitotoxicity of L-dopa and 6-OH-dopa: implications for Parkinson's and Huntington's diseases

scientific article published in June 1990

Excitotoxicity, apoptosis and neuropsychiatric disorders

scientific article

Fenamates protect neurons against ischemic and excitotoxic injury in chick embryo retina ⬇️

scientific article published on February 20, 1998

Fetal alcohol syndrome at the cellular level

scientific article published in June 2004

Focal cortical seizures cause distant thalamic lesions

scientific article published in October 1982

Focus on apoptosis to decipher how alcohol and many other drugs disrupt brain development

scientific article

Glutamate and GABA receptor dysfunction in the fetal alcohol syndrome

scientific article published in June 2002

Glutamate signaling and the fetal alcohol syndrome ⬇️

scientific article published on January 1, 2001

Glutamate transporters and retinal excitotoxicity

scientific article

Glycine agonists: what can they teach us about schizophrenia?

scientific article

Halothane prevents MK-801 neurotoxicity in the rat cingulate cortex

scientific article published in June 1995

High dose magnesium sulfate exposure induces apoptotic cell death in the developing neonatal mouse brain

scientific article

Hypobaric-ischemic conditions produce glutamate-like cytopathology in infant rat brain.

scientific article

Hypothermia enhances protective effect of MK-801 against hypoxic/ischemic brain damage in infant rats

scientific article published on 01 May 1989

Inhibition of cisplatin-induced emesis in ferrets by the non-NMDA receptor antagonists NBQX and CNQX

scientific article published on March 30, 1992

Intrastriatal folic acid mimics the distant but not local brain damaging properties of kainic acid

scientific article published on September 1981

Involvement of glutamate in ischemic neurodegeneration in isolated retina

scientific article published in March 2003

Isoflurane and propofol block neurotoxicity caused by MK-801 in the rat posterior cingulate/retrosplenial cortex

scientific article published in February 1997

Isoflurane-induced apoptosis of neurons and oligodendrocytes in the fetal rhesus macaque brain

scientific article published on March 2014

Isoflurane-induced neuroapoptosis in the developing brain of nonhypoglycemic mice

scientific article published in January 2008

Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain.

scientific article published on April 2010

Isoflurane‐induced apoptosis of oligodendrocytes in the neonatal primate brain ⬇️

scientific article published on October 1, 2012

Kainate-like neurotoxicity of folates

scientific article published in Nature

Ketamine and MK-801 prevent degeneration of thalamic neurons induced by focal cortical seizures

scientific article published in September 1989

Ketamine, phencyclidine, and MK-801 protect against kainic acid-induced seizure-related brain damage

scientific article published in July 1990

Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis

scientific article published in February 1999

Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain

scientific article

L-cysteine, a bicarbonate-sensitive endogenous excitotoxin

scientific article published in May 1990

L-homocysteic acid: an endogenous excitotoxic ligand of the NMDA receptor

scientific article

Lithium Protects Against Anaesthesia Neurotoxicity In The Infant Primate Brain

scientific article published on 8 March 2016

Lithium protects against anesthesia-induced developmental neuroapoptosis

scientific article published on April 2009

Low doses of memantine disrupt memory in adult rats.

scientific article

Luteinizing hormone releasing action of N-methyl aspartate is blocked by GABA or taurine but not by dopamine antagonists

scientific article published on December 15, 1978

MK-801 neurotoxicity in male mice: histologic effects and chronic impairment in spatial learning

scientific article published in January 1996

MK-801 powerfully protects against N-methyl aspartate neurotoxicity

scientific article published on 01 September 1987

MK-801 prevents hypobaric-ischemic neuronal degeneration in infant rat brain

scientific article

Mineralization of the globus pallidus following excitotoxic lesions of the basal forebrain

scientific article

Modeling pediatric head trauma: mechanisms of degeneration and potential strategies for neuroprotection

scientific article published in January 1998

Motor neuron degeneration induced by excitotoxin agonists has features in common with those seen in the SOD-1 transgenic mouse model of amyotrophic lateral sclerosis

scientific article published on 01 February 1996

Multifocal brain damage induced by phencyclidine is augmented by pilocarpine

scientific article published in March 1997

Multiple episodes of mild traumatic brain injury result in impaired cognitive performance in mice

scientific article published in August 2004

Müller cell swelling, glutamate uptake, and excitotoxic neurodegeneration in the isolated rat retina

scientific article published on 01 February 1999

N-Methyl-D-aspartate antagonists and apoptotic cell death triggered by head trauma in developing rat brain

scientific article published on March 1999

NMDA Antagonist Neurotoxicity: Mechanism and Prevention ⬇️

scientific article published on December 6, 1991

Naloxone blocks morphine enhancement of kainic acid neurotoxicity

scientific article published on July 1982

Neuroactive amino acids influence gonadotrophin output by a suprapituitary mechanism in either rodents or primates ⬇️

scientific article published on August 22, 1983

Neuroapoptosis in the infant mouse brain triggered by a transient small increase in blood alcohol concentration

scientific article published on 3 February 2006

Neuroendocrine effects of excitotoxic amino acids

scientific article published on January 1, 1981

Neurotoxicity of NMDA receptor antagonists: an overview

scientific article published on January 1994

New insights and new issues in developmental neurotoxicology

scientific article

Ninety-six hour ketamine infusion with co-administered clonidine for treatment-resistant depression: A pilot randomised controlled trial

scientific article published on 26 February 2016

Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin ⬇️

scientific article published on April 1, 1998

Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity

scientific article published in July 1996

Only certain anticonvulsants protect against kainate neurotoxicity

scientific article published in January 1981

PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures

scientific article published on February 2003

PRO: Anesthesia-induced developmental neuroapoptosis: status of the evidence

scientific article published in June 2008

Parallel recovery of MK-801-induced spatial learning impairment and neuronal injury in male mice

scientific article published in January 1999

Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs

scientific article

Physiological activity depresses synaptic function through an effect on vesicle priming.

scientific article published in June 2006

Potential of ketamine and midazolam, individually or in combination, to induce apoptotic neurodegeneration in the infant mouse brain

scientific article

Potential of xenon to induce or to protect against neuroapoptosis in the developing mouse brain

scientific article published in July 2008

Prevention of trauma-induced neurodegeneration in infant rat brain

scientific article published in June 1996

Prolonged exposure to inhalational anesthetic nitrous oxide kills neurons in adult rat brain

scientific article

Propofol and sodium thiopental protect against MK-801-induced neuronal necrosis in the posterior cingulate/retrosplenial cortex

scientific article

Quantitative analysis of factors influencing neuronal necrosis induced by MK-801 in the rat posterior cingulate/retrosplenial cortex

scientific article published on 01 October 1995

Quisqualate injection into the nucleus basalis magnocellularis produces seizure-related brain damage that is prevented by MK-801.

scientific article

Redox modulation of T-type calcium channels in rat peripheral nociceptors

scientific article

Role of ammonia in reversal of glutamate-mediated Müller cell swelling in the rat retina

scientific article

Role of caspase-3 in ethanol-induced developmental neurodegeneration

scientific article published on 31 May 2005

Seizure-related brain damage induced by cholinergic agents

scientific article published in Nature

Sensitivity of the developing rat brain to hypobaric/ischemic damage parallels sensitivity to N-methyl-aspartate neurotoxicity

scientific article

Spatiotemporal evolution of apoptotic neurodegeneration following traumatic injury to the developing rat brain.

scientific article published on 5 July 2006

Status epilepticus in the limbic system: biochemical and pathological changes.

scientific article published in January 1983

Stereospecificity of the gliotoxic and anti-neurotoxic actions of alpha-aminoadipate

scientific article published on 01 October 1980

Subanesthetic doses of propofol induce neuroapoptosis in the infant mouse brain

scientific article published in June 2008

Swelling of Müller cells induced by AP3 and glutamate transport substrates in rat retina

scientific article published on 01 August 1996

Systemic dipiperidinoethane mimics the convulsant and neurotoxic actions of kainic acid

scientific article published in October 1980

The anti-excitotoxic effects of certain anesthetics, analgesics and sedative-hypnotics

scientific article published on July 1986

The enigma of fetal alcohol neurotoxicity

scientific article

The functional anatomy and pathology of lithium-pilocarpine and high-dose pilocarpine seizures

scientific article published on December 1987

The glutamate synapse in neuropsychiatric disorders. Focus on schizophrenia and Alzheimer's disease

scientific article

The intact isolated (ex vivo) retina as a model system for the study of excitotoxicity

scientific article published on 01 October 1998

The role of specific ions in glutamate neurotoxicity

scientific article published in March 1986

The young: neuroapoptosis induced by anesthetics and what to do about it.

scientific article published on 2 December 2009

Uptake of Exogenous Glutamate and Aspartate by Circumventricular Organs but Not Other Regions of Brain ⬇️

scientific article published on 01 May 1981

alpha 2 adrenergic agonists prevent MK-801 neurotoxicity

scientific article published on 01 July 1995

alpha-Aminoadipate blocks the neurotoxic action of N-methyl aspartate

scientific article published on 01 August 1979

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