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List of works by John Skehel

A Novel I221L Substitution in Neuraminidase Confers High-Level Resistance to Oseltamivir in Influenza B Viruses

scientific article

A Polar Octapeptide Fused to the N-Terminal Fusion Peptide Solubilizes the Influenza Virus HA2 Subunit Ectodomain ⬇️

scientific article published on September 29, 1998

A carbohydrate side chain on hemagglutinins of Hong Kong influenza viruses inhibits recognition by a monoclonal antibody

scientific article

A chimeric protein of simian immunodeficiency virus envelope glycoprotein gp140 and Escherichia coli aspartate transcarbamoylase

scientific article published on May 2004

A human antibody recognizing a conserved epitope of H5 hemagglutinin broadly neutralizes highly pathogenic avian influenza H5N1 viruses.

scientific article

A neutralizing antibody Fab-influenza haemagglutinin complex with an unprecedented 2:1 stoichiometry: characterization and crystallization.

scientific article published in August 2000

A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

scientific article

A soluble domain of the membrane-anchoring chain of influenza virus hemagglutinin (HA2) folds in Escherichia coli into the low-pH-induced conformation

scientific article

A surface plasmon resonance assay for the binding of influenza virus hemagglutinin to its sialic acid receptor

scientific article published in March 1996

Adaptation of Egg-Grown and Transfectant Influenza Viruses for Growth in Mammalian Cells: Selection of Hemagglutinin Mutants with Elevated pH of Membrane Fusion ⬇️

scientific article published on July 7, 1997

Amino acid sequences of haemagglutinins of influenza viruses of the H3 subtype isolated from horses

scientific article

An antibody that prevents the hemagglutinin low pH fusogenic transition

scientific article

An overview of influenza haemagglutinin and neuraminidase

scientific article published on 09 March 2009

Analyses of the Antigenicity of Influenza Haemagglutinin at the pH Optimum for Virus-mediated Membrane Fusion

scientific article published on August 1, 1983

Analysis of murine antibody responses to baculovirus-expressed human immunodeficiency virus type 1 envelope glycoproteins

scientific article

Analysis of residues near the fusion peptide in the influenza hemagglutinin structure for roles in triggering membrane fusion

scientific article

Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein

scientific article published on 21 October 2020

Antigenic and amino acid sequence analyses of influenza viruses of the H1N1 subtype isolated between 1982 and 1984.

scientific article published on January 1985

Antigenic and amino acid sequence analysis of the variants of H1N1 influenza virus in 1986.

scientific article published on January 1987

Antigenic and amino acid sequence variations in the haemagglutinins of type A influenza viruses recently isolated from human subjects

scientific article published on January 1983

Antigenic characterization of influenza A (H1N1) viruses recently isolated from pigs and turkeys in France

scientific article published on January 1985

Assembly of a rod-shaped chimera of a trimeric GCN4 zipper and the HIV-1 gp41 ectodomain expressed in Escherichia coli.

scientific article

Atomic structure of the ectodomain from HIV-1 gp41

scientific article

Author Correction: SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects

scientific article published on 26 August 2020

Avian and human receptor binding by hemagglutinins of influenza A viruses.

scientific article

Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography

scientific article published on October 13, 1992

Binding of the influenza A virus to cell-surface receptors: structures of five hemagglutinin-sialyloligosaccharide complexes determined by X-ray crystallography

scientific article

Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion

scientific article published in February 1982

Changes in the hemagglutinin of H5N1 viruses during human infection – Influence on receptor binding

scientific article

Characterization of influenza virus RNA complete transcripts

scientific article published in January 1982

Characterization of influenza virus RNA transcripts synthesized in vitro

scientific article published on September 1, 1979

Characterization of temperature-sensitive mutants of adenovirus type 5: synthesis of polypeptides in infected cells

scientific article published on 01 August 1974

Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion

scientific article

Coiled coils in both intracellular vesicle and viral membrane fusion

scientific article

Comparative analyses of the specificities of anti-influenza hemagglutinin antibodies in human sera

scientific article published on January 1986

Composition and functions of the influenza fusion peptide

scientific article published on January 2009

Conformational aspects of the acid-induced fusion mechanism of influenza virus hemagglutinin. Circular dichroism and fluorescence studies

scientific article

Conformational changes in the hemagglutinin of influenza virus which accompany heat-induced fusion of virus with liposomes

scientific article published in December 1986

Cryocrystallography of influenza virus hemagglutinin crystals

scientific article published in January 1995

Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain

scientific article

Crystal structures of influenza virus hemagglutinin in complex with high-affinity receptor analogs

scientific article published in August 1994

Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants

scientific article

Crystallization and preliminary X-ray diffraction studies of a monoclonal antibody Fab fragment specific for an influenza virus haemagglutinin and of an escape mutant of that haemagglutinin

scientific article published in December 1990

Crystallization and preliminary X-ray diffraction studies of complexes between an influenza hemagglutinin and Fab fragments of two different monoclonal antibodies

scientific article published on 01 September 1995

Crystallization and preliminary X-ray diffraction studies of the influenza C virus glycoprotein.

scientific article published in September 1996

Crystallization and x-ray diffraction studies on the haemagglutinin glycoprotein from the membrane of influenza virus

scientific article published on May 15, 1977

Crystallographic detection of a second ligand binding site in influenza virus hemagglutinin

scientific article published on January 1992

Crystals of a fragment of influenza haemagglutinin in the low pH induced conformation

scientific article published on 01 March 1994

Deacylation of the hemagglutinin of influenza A/Aichi/2/68 has no effect on membrane fusion properties

scientific article published on September 1991

Determining the structure of an unliganded and fully glycosylated SIV gp120 envelope glycoprotein.

scientific article published in February 2005

Effect of proteolytic processing at two distinct sites on shape and aggregation of an anchorless fusion protein of human respiratory syncytial virus and fate of the intervening segment.

scientific article published in July 2002

Electron microscopic evidence for the axial rotation and inter-domain flexibility of the Fab regions of immunoglobulin G

scientific article published on 01 September 1983

Electron microscopy of antibody complexes of influenza virus haemagglutinin in the fusion pH conformation

scientific article published on January 1995

Electron microscopy of influenza haemagglutinin-monoclonal antibody complexes

scientific article published on 01 December 1983

Electron microscopy of the human respiratory syncytial virus fusion protein and complexes that it forms with monoclonal antibodies

scientific article published in May 2000

Enhanced human receptor binding by H5 haemagglutinins

scientific article

Epitope mapping of cross-reactive monoclonal antibodies specific for the influenza A virus PA and PB2 polypeptides

scientific article published in August 1995

Evidence from studies with a cross-linking reagent that the haemagglutinin of influenza virus is a trimer

scientific article published on June 15, 1977

Evolution of the receptor binding properties of the influenza A(H3N2) hemagglutinin

scientific article

Expression Cloning and Production of Human Heavy-Chain-Only Antibodies from Murine Transgenic Plasma Cells

scientific article

Fred Brown. 31 January 1925 -- 20 February 2004: Elected FRS 1981

biographical article

Full-length influenza hemagglutinin HA2 refolds into the trimeric low-pH-induced conformation

scientific article published in May 2004

Fusion mutants of the influenza virus hemagglutinin glycoprotein

scientific article published in February 1985

Genetics of Influenza Viruses

scientific article

H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis

scientific article

H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes

scientific article

Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors

scientific article

Hemagglutinin Structure and Activities

scientific article published on 08 June 2020

Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals

scientific article published on 01 October 2020

High level expression of soluble glycoproteins in the allantoic fluid of embryonated chicken eggs using a Sendai virus minigenome system

scientific article

Host-mediated selection of influenza virus receptor variants. Sialic acid-alpha 2,6Gal-specific clones of A/duck/Ukraine/1/63 revert to sialic acid-alpha 2,3Gal-specific wild type in ovo.

scientific article

Infectivity studies of influenza virus hemagglutinin receptor binding site mutants in mice

scientific article published on 19 March 2008

Influenza A specific cytotoxic T-cell clones that do not recognize viral glycoproteins ⬇️

scientific article published on December 16, 1982

Influenza Virus Infection of a Cell-cycle Mutant of Chinese Hamster Ovary Cells

scientific article published on April 1, 1977

Influenza a viruses with mutations in the m1 helix six domain display a wide variety of morphological phenotypes

scientific article published on January 2005

Influenza glycoproteins: Hemagglutinin and neuraminidase

Influenza haemagglutinin

scientific article published on 01 May 2002

Influenza hemagglutinin and neuraminidase membrane glycoproteins

scientific article

Influenza hemagglutinin membrane anchor

article published in the Proceedings of the National Academy of Sciences of the United States of America

Ligand recognition by influenza virus. The binding of bivalent sialosides ⬇️

scientific article published on December 15, 1991

Mechanism of neutralization of influenza virus infectivity by antibodies

scientific article published on October 2002

Membrane Fusion by Peptide Analogues of Influenza Virus Haemagglutinin

scientific article published on August 1, 1988

Membrane fusion by influenza hemagglutinin

scientific article published on January 1995

Membrane fusion by surrogate receptor-bound influenza haemagglutinin

scientific article published in May 1999

N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil

scientific article

Plasticity of influenza haemagglutinin fusion peptides and their interaction with lipid bilayers

scientific article

Potent adaptive immune responses induced against HIV-1 gp140 and influenza virus HA by a polyanionic carbomer

scientific article

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

scientific article

Proton nuclear magnetic resonance studies of the binding of sialosides to intact influenza virus ⬇️

scientific article published on August 1, 1992

Recent evolution of equine influenza and the origin of canine influenza

scientific article

Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin

scientific article (publication date: 2000)

Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion

scientific article published on 17 September 2020

Receptor binding by H10 influenza viruses

scientific article

Receptor binding by a ferret-transmissible H5 avian influenza virus

scientific article

Receptor binding by an H7N9 influenza virus from humans

scientific article

Receptor-binding characteristics of monoclonal antibody-selected antigenic variants of influenza virus

scientific article published on January 1987

Recognition of influenza A virus nucleoprotein by an H-2-restricted cytotoxic T-cell clone

scientific article published in March 1984

Recovery of an antiviral antibody response following attrition caused by unrelated infection

scientific article

Refined three-dimensional structure of the Fab fragment of a murine IgGl,lambda antibody

scientific article published in September 1994

Replication: Structure and synthesis of influenza virus complementary RNAs ⬇️

scientific article published on February 25, 1980

Role of virion M2 protein in influenza virus uncoating: specific reduction in the rate of membrane fusion between virus and liposomes by amantadine

scientific article published in April 1994

SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects

scientific article published on 09 July 2020

Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements

scientific article

Sequence elements of the fusion peptide of human respiratory syncytial virus fusion protein required for activity

scientific article published on June 2006

Sequential mutations in hemagglutinins of influenza B virus isolates: definition of antigenic domains

scientific article published on July 1983

Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity

scientific article

Single-particle kinetics of influenza virus membrane fusion

scientific article

Structural basis for oseltamivir resistance of influenza viruses

scientific article published in October 2009

Structural changes in influenza virus haemagglutinin at the pH of membrane fusion

scientific article published in April 1986

Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation ⬇️

scientific article published on January 29, 1981

Structural transitions in influenza haemagglutinin at membrane fusion pH

scientific article published on 27 May 2020

Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes

scientific article published on 20 July 2016

Structure of influenza haemagglutinin at the pH of membrane fusion

scientific article

Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion

scientific article

Structure of influenza virus haemagglutinin complexed with a neutralizing antibody.

scientific article

Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution

scientific article (publication date: 29 January 1981)

Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus

scientific article

Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation

scientific article

Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody

scientific article published on 13 July 2015

Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957

scientific article

Studies of influenza haemagglutinin-mediated membrane fusion

scientific article published on 01 February 1986

Studies of the Binding Properties of Influenza Hemagglutinin Receptor-Site Mutants ⬇️

scientific article published on February 1, 1998

Studies of the membrane fusion activities of fusion peptide mutants of influenza virus hemagglutinin

scientific article published in November 1995

Studies on the adaptation of influenza viruses to MDCK cells

scientific article

Studies on the structure of the haemagglutinin

scientific article published on 01 February 1980

Studies on the structure of the influenza virus haemagglutinin at the pH of membrane fusion

scientific article

Studies using double mutants of the conformational transitions in influenza hemagglutinin required for its membrane fusion activity

scientific article published on November 1996

Studies with crosslinking reagents on the oligomeric structure of the env glycoprotein of HIV.

scientific article

Studies with monoclonal antibodies prepared against X-31 influenza virus haemagglutinin

scientific article

Temperature dependence of fusion by sendai virus

scientific article published in May 2000

The Polypeptides of Adenovirus Type 12

scientific article published on August 1, 1973

The Preparation and Properties of Adenovirus Cores

scientific article published on 01 April 1971

The central structural feature of the membrane fusion protein subunit from the Ebola virus glycoprotein is a long triple-stranded coiled coil ⬇️

scientific article published on May 26, 1998

The effect of the D614G substitution on the structure of the spike glycoprotein of SARS-CoV-2

scientific article

The immunotargeting approach to adjuvant-independent immunization with influenza haemagglutinin

scientific article published in 1993

The influenza A virus nucleoprotein gene controls the induction of both subtype specific and cross-reactive cytotoxic T cells

scientific article

The molecular basis of the specific anti-influenza action of amantadine

scientific article

The receptor-binding and membrane-fusion properties of influenza virus variants selected using anti-haemagglutinin monoclonal antibodies

scientific article

The structure and receptor binding properties of the 1918 influenza hemagglutinin

scientific article

The structure and role of the carbohydrate moieties of influenza virus haemagglutinin

scientific article

The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.

scientific article

The structure of a membrane fusion mutant of the influenza virus haemagglutinin.

scientific article

The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core

scientific article

Thermostability of the human respiratory syncytial virus fusion protein before and after activation: implications for the membrane-fusion mechanism

scientific article published in December 2004

Three-dimensional structure of an antigenic mutant of the influenza virus haemagglutinin ⬇️

scientific article published on October 18, 1984

Use of molecular replacement in the solution of an immunoglobulin Fab fragment structure

scientific article published on 01 August 1991

Variation and infectivity neutralization in influenza

scientific article published on September 2006

X-ray crystallographic determination of the structure of the influenza C virus haemagglutinin-esterase-fusion glycoprotein

scientific article published in May 1999

X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus

scientific article (publication date: 10 May 2003)

X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs

scientific article

[Epizootic swine influenza on animal farms in Brittany]

article

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