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List of works by Alan R. Saltiel

A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes.

scientific article

A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action

scientific journal article

A TUG on glucose transport ⬇️

scientific article published on November 1, 2003

A complex role for adipose tissue macrophages

scientific article published on 04 February 2014

A futile approach to fighting obesity?

scientific article published on 22 October 2015

A pericellular collagenase directs the 3-dimensional development of white adipose tissue

scientific article

A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease

scientific article

A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis

scientific article

APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes

scientific article

Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c

scientific journal article

Activation of glycogen synthase by insulin in 3T3-L1 adipocytes involves c-Cbl-associating protein (CAP)-dependent and CAP-independent signaling pathways.

scientific article

Activation of phosphatidylinositol-3 kinase by nerve growth factor involves indirect coupling of the trk proto-oncogene with src homology 2 domains

scientific article published on October 1, 1992

Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans.

scientific article

Aldolase mediates the association of F-actin with the insulin-responsive glucose transporter GLUT4.

scientific article published on June 1999

Amylin increases cyclic AMP formation in L6 myocytes through calcitonin gene-related peptide receptors

scientific article published on June 1991

An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis

scientific article published on 01 February 2020

An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice

scientific article

An inositol phosphate glycan derived from a Trypanosoma brucei glycosyl phosphatidylinositol promotes protein dephosphorylation in rat epididymal adipocytes

scientific article published on 01 November 1994

Atypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways

scientific article

Autophagy Works Out ⬇️

scientific article published on March 7, 2012

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

scientific article

CAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motility

scientific article

Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3

scientific article published on 08 June 2020

Changes in integrin expression during adipocyte differentiation

scientific article published on September 2005

Circadian Metabolic Regulation through Crosstalk between Casein Kinase 1δ and Transcriptional Coactivator PGC-1α ⬇️

scientific article published on November 3, 2011

Cloning and characterization of a functional peroxisome proliferator activator receptor-gamma-responsive element in the promoter of the CAP gene

scientific article published on March 2000

Cloning and functional characterization of related TC10 isoforms, a subfamily of Rho proteins involved in insulin-stimulated glucose transport

scientific article

Coenzyme A-dependent, ATP-independent acylation of 2-acyl lysophosphatidylinositol in rat liver microsomes

scientific article published on 01 July 1991

Countering inflammatory signals in obesity

scientific article published in May 2014

Derepressing Nuclear Receptors for Metabolic Adaptation ⬇️

scientific article published on November 11, 2011

Design of peptidomimetic ligands for the pp60src SH2 domain

scientific article published on 01 January 1997

Dissociation kinetics of the thyrotropin-receptor complex ⬇️

scientific article published on 01 November 1981

Distinct mutations in the glycogen debranching enzyme found in glycogen storage disease type III lead to impairment in diverse cellular functions

scientific article published on 19 March 2009

Diversity in cellular signaling for nerve growth factor and insulin: Variations on a common theme

scientific article published on 01 October 1991

Emerging functional roles for the glycosyl-phosphatidylinositol membrane protein anchor

scientific article published on July 1990

Epidermal Growth Factor Receptor Targeting Prevents Uncoupling of the Grb2-SOS Complex

scientific article published in Journal of Biological Chemistry

Exocyst function is regulated by effector phosphorylation.

scientific article published on 24 April 2011

Expression of a Catalytically Inert SYP Blocks Activation of Map Kinase Pathway Downstream of P21ras ⬇️

scientific article published on September 14, 1995

Fatty acid remodelling of phosphatidylinositol under conditions of de novo synthesis in rat liver microsomes

scientific article published on 01 July 1991

Fishing Out a Sensor for Anti-inflammatory Oils ⬇️

scientific article published on 01 September 2010

GTP hydrolysis by the Rho family GTPase TC10 promotes exocytic vesicle fusion.

scientific article

Gene Expression Signature in Adipose Tissue of Acromegaly Patients

scientific article published on 18 June 2015

Gene expression changes in subcutaneous adipose tissue due to Cushing's disease.

scientific article

Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes

scientific article published on 27 October 2021

Holding the line on hepatic fat

scientific article published on 01 July 2005

Identification of CAP as a costameric protein that interacts with filamin C.

scientific article

Identification of binding sites on protein targeting to glycogen for enzymes of glycogen metabolism.

scientific article

In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.

scientific article

Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity

scientific article published on 01 January 2007

Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1.

scientific article published on 24 December 2013

Inflammatory links between obesity and metabolic disease

scientific article

Inhibition of AMPK catabolic action by GSK3.

scientific article published on 25 April 2013

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

scientific article published in Journal of Biological Chemistry

Inositol glycan mimics the action of insulin on glucose utilization in rat adipocytes

scientific article published on 01 December 1987

Insulin Resistance in the Defense against Obesity ⬇️

scientific article published on 01 June 2012

Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation

scientific article published on July 1994

Insulin signaling and the regulation of glucose transport.

scientific article

Insulin signaling pathways in time and space.

scientific article

Insulin stimulates phosphatidylinositol 3-phosphate production via the activation of Rab5

scientific article

Insulin stimulates the release from liver plasma membranes of a chemical modulator of pyruvate dehydrogenase

scientific article published on 01 October 1981

Insulin stimulates the tyrosine phosphorylation of caveolin

scientific article published on June 1995

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

scientific article published in Journal of Biological Chemistry

Insulin-like Growth Factor-I-mediated Neurite Outgrowth in Vitro Requires Mitogen-activated Protein Kinase Activation ⬇️

scientific article published on August 22, 1997

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

scientific article

Insulin-stimulated Interaction between insulin receptor substrate 1 and p85alpha and activation of protein kinase B/Akt require Rab5.

scientific article

Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells

scientific article published on August 1997

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

scientific article

Lipid phosphatases as drug discovery targets for type 2 diabetes.

scientific article

MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity

scientific article

Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins.

scientific article published on 22 August 2006

Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity

scientific article

Metabolic effects of troglitazone in the Goto-Kakizaki rat, a non-obese and normolipidemic rodent model of non-insulin-dependent diabetes mellitus

scientific article published in February 1997

Metabolism: Inflammation keeps old mice healthy.

scientific article published on 18 November 2015

Mitogen-activated protein kinase kinase inhibition decreases growth hormone stimulated transcription mediated by STAT5

scientific article published on 01 October 1997

Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin

scientific article

More TORC for the gluconeogenic engine

scientific article

Negative Modulation of Membrane Localization of the Raf-1 Protein Kinase by Hyperphosphorylation

scientific article published in Journal of Biological Chemistry

Negative Regulation of the RalGAP Complex by 14-3-3 ⬇️

scientific article published on February 5, 2013

New perspectives into the molecular pathogenesis and treatment of type 2 diabetes

scientific article (publication date: 23 February 2001)

Novel phosphotyrosine mimetics in the design of peptide ligands for pp60src SH2 domain

article by Aurash Shahripour et al published June 1996 in Bioorganic & Medicinal Chemistry Letters

Okadaic acid stimulates the activity of microtubule associated protein kinase in PC-12 pheochromocytoma cells

scientific article

Otopetrin 1 protects mice from obesity-associated metabolic dysfunction through attenuating adipose tissue inflammation.

scientific article published on 30 December 2013

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

scientific journal article

PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism

scientific journal article

Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes

scientific article published on October 2008

Phosphatidylinositol 3-kinase is necessary and sufficient for insulin-stimulated stress fiber breakdown

scientific article published on November 1996

Phosphoinositides: Key modulators of energy metabolism

scientific article

Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking

scientific article

Pleiotropic signaling from receptor tyrosine kinases

scientific article

Preferred apical distribution of glycosyl-phosphatidylinositol (GPI) anchored proteins: a highly conserved feature of the polarized epithelial cell phenotype

scientific article published on February 1990

Proliferin induces endothelial cell chemotaxis through a G protein-coupled, mitogen-activated protein kinase-dependent pathway

scientific article published on 01 July 1997

Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling.

scientific article

Putative mediators of insulin action regulate hepatic acetyl CoA carboxylase activity ⬇️

scientific article published on February 10, 1983

Putting the brakes on insulin signaling.

scientific article published on December 2003

Rab5 proteins regulate activation and localization of target of rapamycin complex 1.

scientific article

Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion.

scientific article published on 02 January 2014

Ral's engagement with the exocyst: breaking up is hard to do.

scientific article

RalA-exocyst-dependent recycling endosome trafficking is required for the completion of cytokinesis

scientific article published on 6 October 2006

Regulation of System A Amino Acid Transport in 3T3-L1 Adipocytes by Insulin ⬇️

scientific article published on February 6, 1998

Regulation of glucose transport by insulin: traffic control of GLUT4 ⬇️

scientific article published on May 23, 2012

Regulation of the mouse protein targeting to glycogen (PTG) promoter by the FoxA2 forkhead protein and by 3',5'-cyclic adenosine 5'-monophosphate in H4IIE hepatoma cells

scientific article published on 20 April 2006

Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C.

scientific article published on May 1996

Role of protein targeting to glycogen (PTG) in the regulation of protein phosphatase-1 activity

scientific article published on August 1997

Roles for PI(3,5)P2 in nutrient sensing through TORC1.

scientific article published on 29 January 2014

SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling.

scientific article

Second messengers of insulin action

scientific article published in January 1990

Short-term action of insulin onAplysia neurons: Generation of a possible novel modulator of ion channels ⬇️

scientific article published on January 1, 1991

Signal transduction in insulin action

scientific article published on 01 April 1990

Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes.

scientific article

Spatial Compartmentalization in the Regulation of Glucose Metabolism by Insulin

scientific article published on 01 December 1999

Spatial determinants of specificity in insulin action

scientific article published in May 1998

Staying in SHIP shape

scientific article published in February 2005

Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor

scientific article

Structure-based design of novel, dipeptide ligands targeting the pp60Src SH2 domain

scientific article published in 1997

Subcellular Compartmentalization of Insulin Signaling Processes and GLUT4 Trafficking Events

Synip

article

Synthesis of phosphatidylinositol in rat liver microsomes is accompanied by the rapid formation of lysophosphatidylinositol

scientific article published on 01 July 1991

T-ing up inflammation in fat

scientific article published on 01 August 2009

TC10 and insulin-stimulated glucose transport

scientific article published on January 2006

TC10 is regulated by caveolin in 3T3-L1 adipocytes

scientific article

TC10alpha is required for insulin-stimulated glucose uptake in adipocytes

scientific article published on 28 September 2006

TIRFing out Studies on Glut4 Trafficking

scientific article published on 01 January 2007

The Activation of Glycogen Synthase by Insulin Switches from Kinase Inhibition to Phosphatase Activation during Adipogenesis in 3T3-L1 Cells ⬇️

scientific article published on June 5, 1998

The Role of 4-phosphonodifluoromethyl- and 4-phosphono-phenylalanine in the selectivity and cellular uptake of SH2 domain ligands

scientific article published in 1997

The Stimulation of pp42mapkinase by Insulin Does Not Correlate with Its Metabolic Actions in Cells Overexpressing Mutant Insulin Receptors

scientific article published on 01 October 1993

The TBK1/IKKε inhibitor amlexanox improves dyslipidemia and prevents atherosclerosis

scientific article published in 2022

The distribution of glycosyl-phosphatidylinositol anchored proteins is differentially regulated by serum and insulin

scientific article published on October 1989

The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin

scientific article (publication date: 10 April 2003)

The lipid kinase PI4KIIIβ is highly expressed in breast tumors and activates Akt in cooperation with Rab11a

scientific article

The protein kinase IKKepsilon regulates energy balance in obese mice

scientific article

The regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes. Evidence for a potential role for DARPP-32 in insulin action.

scientific article

The role of glucose metabolites in the activation and translocation of glycogen synthase by insulin in 3T3-L1 adipocytes

scientific article published on September 1999

The roles of Cbl-b and c-Cbl in insulin-stimulated glucose transport

scientific article published on 2 July 2003

The stomatin/prohibitin/flotillin/HflK/C domain of flotillin-1 contains distinct sequences that direct plasma membrane localization and protein interactions in 3T3-L1 adipocytes

scientific article published on 14 February 2005

Thiazolidinediones and insulin resistance: peroxisome proliferatoractivated receptor gamma activation stimulates expression of the CAP gene

scientific article published on December 1998

Thyrotropin binding to porcine thyroid plasma membranes: Kinetic and thermodynamic analyses

scientific article published on 01 November 1982

Troglitazone Increases System A Amino Acid Transport in 3T3-L1 Cells ⬇️

scientific article published on March 1, 1998

Von Gierke's disease adopts an orphan (and its partner).

scientific article published on 17 February 2009

White, brown, and beige; type 2 immunity gets hot.

scientific article

You are what you secrete

scientific article published in August 2001

Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNA

scientific article

c-Myc Does Not Require Max for Transcriptional Activity in PC-12 Cells

scientific article published on 01 June 1994

p75 Neurotrophin Receptor Regulates Energy Balance in Obesity.

scientific article published on 30 December 2015

p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity

scientific journal article

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