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List of works by Markku Mäki

A B-Cell Gene Signature Correlates With the Extent of Gluten-Induced Intestinal Injury in Celiac Disease

scientific article

A Prospective Study on the Usefulness of Duodenal Bulb Biopsies in Celiac Disease Diagnosis in Children: Urging Caution

scientific article published on 5 January 2016

A new locus for coeliac disease mapped to chromosome 15 in a population isolate

A novel human glycosyltransferase: primary structure and characterization of the gene and transcripts

scientific article (publication date: 12 September 2003)

A single conformational transglutaminase 2 epitope contributed by three domains is critical for celiac antibody binding and effects

scientific article published on December 22, 2011

Accuracy in Diagnosis of Celiac Disease Without Biopsies in Clinical Practice

scientific article published on 14 June 2017

Advances in the treatment of coeliac disease: an immunopathogenic perspective ⬇️

scientific article published on 06 August 2013

Altered duodenal microbiota composition in celiac disease patients suffering from persistent symptoms on a long-term gluten-free diet

scientific article

Altered small-bowel mucosal vascular network in untreated coeliac disease

scientific article published on 01 January 2009

Alternative mRNA splicing of SAP30L regulates its transcriptional repression activity

scientific journal article

Anemia and Iron Deficiency in Children With Potential Celiac Disease

scientific article published on 01 January 2017

Anemia in Pediatric Celiac Disease: Association With Clinical and Histological Features and Response to Gluten-free Diet

scientific article published in January 2017

Angiogenesis-related gene expression analysis in celiac disease.

scientific article

Antibodies against deamidated gliadin peptides in early-stage celiac disease

scientific article published on 01 September 2011

Antibodies in celiac disease: implications beyond diagnostics.

scientific article

Antibody biomarker discovery through in vitro directed evolution of consensus recognition epitopes

scientific article

Antiendomysial and antihuman recombinant tissue transglutaminase antibodies in the diagnosis of coeliac disease

scientific article published on 01 January 2005

Antimitochondrial antibodies in patients with epilepsy

scientific article published on 01 August 2005

Are Transglutaminase 2 Inhibitors Able to Reduce Gliadin-Induced Toxicity Related to Celiac Disease? A Proof-of-Concept Study

article

Association study of the IL18RAP locus in three European populations with coeliac disease

scientific article published on 22 December 2008

At-Risk Screened Children with Celiac Disease are Comparable in Disease Severity and Dietary Adherence to Those Found because of Clinical Suspicion: A Large Cohort Study

scientific article

Benefits of a gluten-free diet for asymptomatic patients with serologic markers of celiac disease

scientific article published on 13 May 2014

Burden of illness and use of health care services before and after celiac disease diagnosis in children

scientific article published in July 2013

Burden of illness in screen-detected children with celiac disease and their families

scientific article published on 01 October 2012

CYP3A4-Catalyzed Simvastatin Metabolism as a Non-Invasive Marker of Small Intestinal Health in Celiac Disease ⬇️

scientific article published on June 4, 2013

Celiac Disease-Specific TG2-Targeted Autoantibodies Inhibit Angiogenesis Ex Vivo and In Vivo in Mice by Interfering with Endothelial Cell Dynamics

scientific article (publication date: 2013)

Celiac disease IgA modulates vascular permeability in vitro through the activity of transglutaminase 2 and RhoA

scientific article published on 13 August 2009

Celiac disease and bone fractures: a systematic review and meta-analysis

scientific article

Celiac disease and health-related quality of life

scientific article published on February 2011

Celiac disease autoimmunity and hip fracture risk: findings from a prospective cohort study

scientific article published in April 2015

Celiac disease in patients with severe liver disease: gluten-free diet may reverse hepatic failure

scientific article

Celiac disease patient IgA antibodies induce endothelial adhesion and cell polarization defects via extracellular transglutaminase 2.

scientific article

Celiac disease without villous atrophy in children: a prospective study

scientific article published on 18 April 2010

Celiac disease--a diagnostic and therapeutic challenge

scientific article published in January 2010

Celiac disease-related antibodies in an epilepsy cohort and matched reference population

scientific article

Celiac disease: from inflammation to atrophy: a long-term follow-up study

scientific article published on 01 July 2005

Celiac disease: past, present, and future challenges: dedicated to the memory of our friend and colleague, Prof David Branski (1944-2013).

scientific article

Changes in body mass index on a gluten-free diet in coeliac disease: a nationwide study

scientific article published on 28 January 2012

Changing phenotype of celiac disease after long-term gluten exposure

scientific article published on 01 October 2008

Chapter 5.1.1. Coeliac Disease

scientific article published in April 2018

Clinical Characteristics and the Dietary Response in Celiac Disease Patients Presenting With or Without Anemia

scientific article published on 15 June 2016

Clinical benefit of gluten-free diet in screen-detected older celiac disease patients

scientific article

Coeliac disease autoantibodies in seminal plasma from cases with screen-detected coeliac disease

scientific article published on 01 January 2009

Coeliac disease in 2013: new insights in dietary-gluten-induced autoimmunity

scientific article published on 10 December 2013

Coeliac disease--a diagnostic and therapeutic challenge

scientific article published on September 2010

Comparison of a novel whole blood transglutaminase-based ELISA with a whole blood rapid antibody test and established conventional serological celiac disease assays

scientific article published in November 2008

Complete small intestine mucosal recovery is obtainable in the treatment of celiac disease

scientific article published on 01 January 2004

Correction: Celiac Disease–Specific TG2-Targeted Autoantibodies Inhibit Angiogenesis Ex Vivo and In Vivo in Mice by Interfering with Endothelial Cell Dynamics

scientific article published on 6 January 2014

Cost-effective HLA typing with tagging SNPs predicts celiac disease risk haplotypes in the Finnish, Hungarian, and Italian populations

article

Crypt hyperplastic enteropathy in distal duodenum in Helicobacter pylori infection - report of two cases without evidence of celiac disease

scientific article published on January 2017

DNA-binding and -bending activities of SAP30L and SAP30 are mediated by a zinc-dependent module and monophosphoinositides

scientific article

Deamidated gliadin peptides form epitopes that transglutaminase antibodies recognize

scientific article published on 01 March 2008

Deep sequencing of blood and gut T-cell receptor β-chains reveals gluten-induced immune signatures in celiac disease

scientific article published on 21 December 2017

Deficient activity of mammalian prolyl oligopeptidase on the immunoactive peptide digestion in coeliac disease

scientific article published on 01 May 2007

Degree of damage to the small bowel and serum antibody titers correlate with clinical presentation of patients with celiac disease.

scientific article published on 9 October 2012

Delayed celiac disease diagnosis predisposes to reduced quality of life and incremental use of health care services and medicines: A prospective nationwide study.

scientific article

Diagnosing mild enteropathy celiac disease: a randomized, controlled clinical study

scientific article published on 24 November 2008

Diagnostic Accuracy of Point of Care Tests for Diagnosing Celiac Disease: A Systematic Review and Meta-Analysis

scientific article published on 01 August 2019

Diet improves perception of health and well-being in symptomatic, but not asymptomatic, patients with celiac disease

scientific article published on 26 October 2010

Dietary Factors and Mucosal Immune Response in Celiac Disease Patients Having Persistent Symptoms Despite a Gluten-free Diet

scientific article published on 2 March 2018

Duodenal intraepithelial lymphocytosis: celiac disease or not?

scientific article published on 01 July 2009

Early microbial markers of celiac disease ⬇️

scientific article

Elevated serum anti-Saccharomyces cerevisiae, anti-I2 and anti-OmpW antibody levels in patients with suspicion of celiac disease

scientific article published on 22 May 2008

Endomysial antibodies predict celiac disease irrespective of the titers or clinical presentation

scientific article

Enzymatic detoxification of gluten by germinating wheat proteases: implications for new treatment of celiac disease.

scientific article

Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies

scientific article published on 11 May 2017

Erratum: Corrigendum: Multiple common variants for celiac disease influencing immune gene expression

article

European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020

scientific article published on 01 January 2020

Factors associated with dietary adherence in celiac disease: a nationwide study

scientific article published on 23 October 2012

Factors associated with growth disturbance at celiac disease diagnosis in children: a retrospective cohort study

scientific article published on 6 October 2015

Factors associated with long diagnostic delay in celiac disease

scientific article

Fingertip rapid point-of-care test in adult case-finding in coeliac disease

scientific article

Future treatment strategies for celiac disease.

scientific article published on 24 May 2012

Galactosylation of Serum IgA1 O-Glycans in Celiac Disease ⬇️

scientific article published on October 12, 2010

Gastrointestinal Symptoms Increase the Burden of Illness in Dermatitis Herpetiformis: A Prospective Study

scientific article published on 31 May 2016

Gastrointestinal Symptoms in Celiac Disease Patients on a Long-Term Gluten-Free Diet

scientific article published on 14 July 2016

Gastrointestinal symptoms and quality of life in screen-detected celiac disease

scientific article published on 5 June 2012

Gastrointestinal symptoms, quality of life and bone mineral density in mild enteropathic coeliac disease: a prospective clinical trial

scientific article published in March 2010

Gene expression in TGFbeta-induced epithelial cell differentiation in a three-dimensional intestinal epithelial cell differentiation model

scientific article

Genome-wide transcriptomic analysis of intestinal mucosa in celiac disease patients on a gluten-free diet and post gluten challenge

scientific article published on 31 July 2020

Genomewide linkage analysis of celiac disease in Finnish families

scientific article published on 19 November 2001

Gluten-Induced Extra-Intestinal Manifestations in Potential Celiac Disease-Celiac Trait

Gluten-dependent small bowel mucosal transglutaminase 2-specific IgA deposits in overt and mild enteropathy coeliac disease

scientific article published on 01 October 2008

Gluten-free diet and quality of life in patients with screen-detected celiac disease.

scientific article

Gluten-sensitive hypertransaminasemia in celiac disease: an infrequent and often subclinical finding

scientific article published on 19 April 2011

Glutenase ALV003 attenuates gluten-induced mucosal injury in patients with celiac disease

scientific article published on 25 February 2014

HLA-DQ typing in the diagnosis of celiac disease

scientific article published on 01 March 2002

Histological, immunohistochemical and mRNA gene expression responses in coeliac disease patients challenged with gluten using PAXgene fixed paraffin-embedded duodenal biopsies

scientific article published on 15 November 2019

IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease

scientific article

IgA-class autoantibodies against neuronal transglutaminase, TG6 in celiac disease: no evidence for gluten dependency

scientific article

IgA-class transglutaminase antibodies in evaluating the efficacy of gluten-free diet in coeliac disease

scientific article published on 01 March 2002

Immunohistochemical features in antiendomysium positive patients with normal villous architecture

scientific article published on 01 March 2006

Impaired epithelial integrity in the duodenal mucosa in early stages of celiac disease

scientific article published on 18 June 2014

In vitromodels for gluten toxicity: relevance for celiac disease pathogenesis and development of novel treatment options ⬇️

scientific article published on January 26, 2012

Increasing prevalence and high incidence of celiac disease in elderly people: a population-based study

scientific article

Inhibition of epithelial growth factor receptor signalling does not preserve epithelial barrier function after in vitro gliadin insult

scientific article published in January 2009

Inhibition of transglutaminase 2 enzymatic activity ameliorates the anti-angiogenic effects of coeliac disease autoantibodies

scientific article published on 01 April 2010

Injection of celiac disease patient sera or immunoglobulins to mice reproduces a condition mimicking early developing celiac disease

scientific article published on 12 September 2014

Interactions of functional apolipoprotein E gene promoter polymorphisms with smoking on aortic atherosclerosis

scientific article published on 15 October 2008

Intestinal transglutaminase 2 specific antibody deposits in non-responsive coeliac disease

scientific article published on 20 April 2010

Intraepithelial lymphocytes in celiac disease

scientific article published on 01 June 2003

Is There a Role for Duodenal Bulb Biopsies in Celiac Disease Diagnostics?

scientific article published on 13 April 2016

It is the compliance, not milligrams of gluten, that is essential in the treatment of celiac disease

scientific article published on 01 December 2004

Latent coeliac disease or coeliac disease beyond villous atrophy?

scientific article published on October 2007

Long-term consumption of oats in adult celiac disease patients

scientific article

Lower economic status and inferior hygienic environment may protect against celiac disease

Lymphonodular hyperplasia of the terminal ileum associated with colitis shows an increase gammadelta+ t-cell density in children

scientific article published on 01 March 2002

Measuring Change In Small Intestinal Histology In Patients With Celiac Disease

scientific article published on 20 February 2018

Multiple common variants for celiac disease influencing immune gene expression

scientific article

Multiple independent variants in 6q21-22 associated with susceptibility to celiac disease in the Dutch, Finnish and Hungarian populations

scientific article

Murine ortholog of the novel glycosyltransferase, B3GTL: primary structure, characterization of the gene and transcripts, and expression in tissues

scientific article published in August 2006

No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease

scientific article

No observed local immunological response at cell level after five years of oats in adult coeliac disease

scientific article

Nonbiopsy Approach for Celiac Disease Is Accurate When Using Exact Duodenal Histomorphometry: Prospective Study in 2 Countries

scientific article published on 14 April 2020

Nutritional status in adolescents and young adults with screen-detected celiac disease

scientific article published in May 2005

Oats can diversify a gluten-free diet in celiac disease and dermatitis herpetiformis

scientific article

Oats do not induce systemic or mucosal autoantibody response in children with coeliac disease

scientific article published in May 2009

Patients' experiences and perceptions of living with coeliac disease - implications for optimizing care

scientific article published on March 1, 2012

Persistently positive gliadin antibodies without transglutaminase antibodies in the elderly: Gluten intolerance beyond coeliac disease

scientific article published on 08 June 2011

Peters'-plus syndrome is a congenital disorder of glycosylation caused by a defect in the beta1,3-glucosyltransferase that modifies thrombospondin type 1 repeats

scientific article published on January 2009

Phylogenetic analysis of the SAP30 family of transcriptional regulators reveals functional divergence in the domain that binds the nuclear matrix.

scientific article published on 30 June 2009

Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia.

scientific article published on 29 August 2016

Population screening for coeliac disease in primary care by district nurses using a rapid antibody test: diagnostic accuracy and feasibility study

scientific article published on 6 December 2007

Positive serum antigliadin antibodies without celiac disease in the elderly population: does it matter?

scientific article published on 01 October 2010

Prediction of clinical and mucosal severity of coeliac disease and dermatitis herpetiformis by quantification of IgA/IgG serum antibodies to tissue transglutaminase

scientific article

Predictors of persistent symptoms and reduced quality of life in treated coeliac disease patients: a large cross-sectional study

scientific article

Presentation of Celiac Disease in Finnish Children Is No Longer Changing: A 50-Year Perspective

scientific article

Prevalence and associated factors of abnormal liver values in children with celiac disease.

scientific article published on 2 June 2016

Prevalence of Celiac disease among children in Finland

scientific article

Prognosis of unrecognized coeliac disease as regards mortality: A population-based cohort study

Prospective antibody case finding of coeliac disease in type‐1 diabetes children: need of biopsy revisited ⬇️

scientific article published on January 4, 2013

Quality of Life and Gastrointestinal Symptoms in Long-Term Treated Dermatitis Herpetiformis Patients: A Cross-Sectional Study in Finland

scientific article published on 13 August 2015

Recent advances in the development of new treatments for celiac disease ⬇️

scientific article published on August 28, 2012

Reply: To PMID 24837306

scientific article published on 22 November 2014

Resurrection of gliadin antibodies in coeliac disease. Deamidated gliadin peptide antibody test provides additional diagnostic benefit

scientific article published on 01 December 2007

Revival of gliadin antibodies in the diagnostic work-up of celiac disease

scientific article published on 01 March 2010

RhoB is associated with the anti-angiogenic effects of celiac patient transglutaminase 2-targeted autoantibodies

scientific article published on 06 January 2012

Rotavirus Vaccination Does Not Increase Type 1 Diabetes and May Decrease Celiac Disease in Children and Adolescents

scientific article published on 01 May 2019

Safe gluten threshold for patients with celiac disease: some patients are more tolerant than others

scientific article (publication date: July 2007)

Safety and efficacy of AMG 714 in adults with coeliac disease exposed to gluten challenge: a phase 2a, randomised, double-blind, placebo-controlled study

scientific article published on 04 September 2019

Secretion of celiac disease autoantibodies after in vitro gliadin challenge is dependent on small-bowel mucosal transglutaminase 2-specific IgA deposits

scientific article

Serodiagnostic assays for celiac disease based on the open or closed conformation of the autoantigen, transglutaminase 2

scientific article published on 09 March 2011

Serological responses to microbial antigens in celiac disease patients during a gluten-free diet

scientific article

Serum fatty acid profile in celiac disease patients before and after a gluten-free diet.

scientific article published in January 2009

Serum fatty acid profile in subjects with irritable bowel syndrome

scientific article published on 15 November 2010

Small bowel transglutaminase 2-specific IgA deposits in dermatitis herpetiformis

scientific article published on 01 July 2014

Small- bowel mucosal changes and antibody responses after low- and moderate-dose gluten challenge in celiac disease ⬇️

scientific article published on November 24, 2011

Small-bowel mucosal transglutaminase 2-specific IgA deposits in coeliac disease without villous atrophy: a prospective and randomized clinical study.

scientific article

Spontaneous negative seroconversion of endomysial antibodies does not exclude subsequent celiac disease

scientific article published on 01 November 2011

Symptom-detected and screen-detected celiac disease and adult height: a large cohort study.

scientific article published in September 2012

TGF-beta induces the expression of SAP30L, a novel nuclear protein

scientific article

The Long-Term Consumption of Oats in Celiac Disease Patients Is Safe: A Large Cross-Sectional Study

scientific article

The duodenal microbiota composition of adult celiac disease patients is associated with the clinical manifestation of the disease

scientific article

The prevalence of celiac disease in Europe: Results of a centralized, international mass screening project ⬇️

scientific article published on December 1, 2010

Thioredoxin is involved in endothelial cell extracellular transglutaminase 2 activation mediated by celiac disease patient IgA.

scientific article

Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa

scientific article published on 11 April 2008

Transglutaminase 2-specific coeliac disease autoantibodies induce morphological changes and signs of inflammation in the small-bowel mucosa of mice

scientific article published on 9 August 2016

Transglutaminase 2-targeted autoantibodies in celiac disease: Pathogenetic players in addition to diagnostic tools?

scientific article published on 12 June 2010

Transglutaminase 6 antibodies in the diagnosis of gluten ataxia

scientific article

Transient celiac autoimmunity or just temporary fluctuation?

scientific article published on 01 May 2012

Type 1 and type 2 diabetes in celiac disease: prevalence and effect on clinical and histological presentation

scientific article

Type 1 diabetes is associated with enterovirus infection in gut mucosa

scientific article published on 7 February 2012

Use of health care services and pharmaceutical agents in coeliac disease: a prospective nationwide study

scientific article

Usefulness of small-bowel mucosal transglutaminase-2 specific autoantibody deposits in the diagnosis and follow-up of celiac disease

scientific article published on 01 August 2010

Utility of the new ESPGHAN criteria for the diagnosis of celiac disease in at-risk groups

scientific article published in March 2012

Validation of morphometric analyses of small-intestinal biopsy readouts in celiac disease

scientific article

[Update on current care guidelines. Celiac disease]

scientific article published on 01 January 2005

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