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List of works by Steven Shafer

A comparison of parametric with semiparametric analysis of the concentration versus effect relationship of metocurine in dogs and pigs.

scientific article published in June 1989

A comparison of spectral edge, delta power, and bispectral index as EEG measures of alfentanil, propofol, and midazolam drug effect

scientific article published in January 1997

A model of the ventilatory depressant potency of remifentanil in the non-steady state

scientific article published in October 2003

A phase I, two-center study of the pharmacokinetics and pharmacodynamics of dexmedetomidine in children.

scientific article published on December 2006

A&A case reports: a progress report and an update on requirements for patient consent

scientific article published in December 2014

Additivity versus synergy: a theoretical analysis of implications for anesthetic mechanisms

scientific article published in August 2008

All Boxes Are Black.

scientific article

All Models Are Wrong ⬇️

scientific article published on February 1, 2012

Allometry, Shallometry!

scientific article published on 01 May 2016

An efficient control strategy for dosage regimens.

scientific article published on February 1994

Anesthesia & Analgesia's 2015 Collection on the Perioperative Surgical Home

scientific article published in May 2015

Anesthesia & Analgesia's collection on the perioperative surgical home

scientific article published in May 2014

Anesthesia & Analgesia Policy on Institutional Review Board Approval and Informed Consent for Research ⬇️

scientific article published on March 1, 2011

Anesthesia and analgesia case reports

scientific article published in March 2013

Anesthesia matters: statistical anomaly or new paradigm?

scientific article published in January 2008

Anesthesiologists make a difference

scientific article

Application of Bispectral Index and Narcotrend index to the measurement of the electroencephalographic effects of isoflurane with and without burst suppression

scientific article published in October 2004

Application of semilinear canonical correlation to the measurement of opioid drug effect

scientific article published in December 1992

Arterial and venous pharmacokinetics of ropivacaine with and without epinephrine after thoracic paravertebral block.

scientific article

Artifact robustness, inter- and intraindividual baseline stability, and rational EEG parameter selection

scientific article published in January 2002

Artificial Intelligence for Everyone

scientific article published on 22 November 2017

Authorship wanting: dead or alive

scientific article published in October 2016

Automated responsiveness monitor to titrate propofol sedation

scientific article published in September 2009

Biopharmaceutics of a New Transdermal Fentanyl Device ⬇️

scientific article published on September 1, 1995

Bispectral index dynamics during propofol hypnosis is similar in red-haired and dark-haired subjects

scientific article

Broken Hearts

scientific article published in May 2016

CORRECTION

Calculating the probability of random sampling for continuous variables in submitted or published randomised controlled trials.

scientific article

Carfentanil: a weapon of mass destruction

scientific article published on 14 January 2019

Case scheduling for dummies

scientific article published in December 2006

Caveat Lector

scientific article published on 01 June 2012

Caveat lector

scientific article

Cephalad movement of morphine and fentanyl in humans after intrathecal injection

scientific article

Cerebrospinal fluid pharmacokinetics and pharmacodynamics of intrathecal neostigmine methylsulfate in humans.

scientific article published in November 1998

Changes in Anesthesia & Analgesia for 2009.

scientific article published in January 2009

Comparison of plasma compartment versus two methods for effect compartment--controlled target-controlled infusion for propofol

scientific article published in February 2000

Comparison of some control strategies for three-compartment PK/PD models

scientific article published in December 1994

Computer-controlled epidural infusion to targeted cerebrospinal fluid concentrations in humans. Clonidine.

scientific article

Con: The black box warning on droperidol should not be removed (but should be clarified!).

scientific article published in May 2008

Consent contraindicated?

scientific article published in April 2010

Constant versus optimal plasma concentrations

scientific article published in March 1993

Correlation of approximate entropy, bispectral index, and spectral edge frequency 95 (SEF95) with clinical signs of "anesthetic depth" during coadministration of propofol and remifentanil

scientific article published in March 2003

Critical thinking in anesthesia: eighth Honorary FAER Research Lecture

scientific article published in April 2009

Deadly heat: economics of continuous temperature monitoring during general anesthesia

scientific article published in December 2014

Derivation and cross-validation of pharmacokinetic parameters for computer-controlled infusion of lidocaine in pain therapy

scientific article published in May 1996

Determination of the pharmacodynamic interaction of propofol and remifentanil during esophagogastroduodenoscopy in children

scientific article

Dexmedetomidine decreases cerebral blood flow velocity in humans

scientific article published in March 1993

Did our brains fall out?

scientific article

Differential activation of trigeminal C or Adelta nociceptors by infrared diode laser in rats: behavioral evidence

scientific article

Dittrick's Missing Editorial About Apgar's Score.

scientific article published in May 2015

Do distribution volumes and clearances relate to tissue volumes and blood flows? A computer simulation

scientific article published on 13 June 2006

Does size matter?

scientific article published on 01 September 1998

Editor's note: notice of retraction

scientific article

Editor's note: notices of retraction

Retraction of 3 articles by Dr. Yoshitaka Fujii

Editor's note: notices of retractions

Retraction of articles by Dr. Yoshitaka Fujii

Editorʼs Note: Notices of Retraction

retraction notice in Anesthesia & Analgesia detailing 22 individual retraction notice for articles of Joachim Boldt

Education and management case reports

scientific article

Efficient trial design for eliciting a pharmacokinetic-pharmacodynamic model-based response surface describing the interaction between two intravenous anesthetic drugs

scientific article published in February 2002

Estimating the rate of thiopental blood-brain equilibration using pseudo steady state serum concentrations

scientific article

Estimation of optimal modeling weights for a Bayesian-based closed-loop system for propofol administration using the bispectral index as a controlled variable: a simulation study

scientific article published in December 2007

Evolving clinically useful predictors of recovery from intravenous anesthetics

scientific article published in November 1995

Exercise produces sensitivity to metocurine.

scientific article published on June 1989

Experience = Education: Time for the Next Step

scientific article published in July 2015

From d -tubocurarine to sugammadex: the contributions of T. Cecil Gray to modern anaesthetic practice ⬇️

scientific article published on May 24, 2011

Full disclosure matters!

scientific article published in March 2008

Hot air or full steam ahead? An empirical pharmacokinetic model of potent inhalational agents.

scientific article published in April 2000

How "Volatile" Is the Protection Provided by Inhalational Anesthetics?

scientific article

I appreciate the dialog between Drs. Anderson and Schonfeld and Murphy et al

Impact of cervical effacement and fetal station on progress during the first stage of labor: a biexponential model.

scientific article

Improving the clinical utility of anesthetic drug pharmacokinetics

scientific article published on March 1, 1992

In Response

scientific article published on 01 February 2015

In silico and in vitro pharmacogenetic analysis in mice

scholarly article

In silico pharmacogenetics of warfarin metabolism.

scientific article published on May 2006

Influence of administration rate on propofol plasma-effect site equilibration

scientific article

Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development

scientific article published in January 1997

Inhalation versus intravenous anesthesia: a fictitious debate between E.I. Eger II and P.F. White

scientific article published in May 1996

Inhaled anesthetics do not combine to produce synergistic effects regarding minimum alveolar anesthetic concentration in rats

scientific article published in August 2008

Is a new paradigm needed to explain how inhaled anesthetics produce immobility?

scientific article published on September 2008

Is synergy the rule? A review of anesthetic interactions producing hypnosis and immobility

scientific article

Isoflurane antagonizes the capacity of flurothyl or 1,2-dichlorohexafluorocyclobutane to impair fear conditioning to context and tone

scientific article published in April 2003

Letter to the Editor on “Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial”

scientific article published on 30 March 2018

Linearity of pharmacokinetics and model estimation of sufentanil

scientific article published in December 1995

Location, location, location

scientific article published on 01 March 2000

MAC Attack?

scientific article published in December 2003

MIDAZOLAM VERSUS LORAZEPAM FOR SHORT TERM SEDATION IN CRITICALLY ILL PATIENTS- A DOUBLE BLIND STUDY

Making a difference in perioperative infection

scientific article published in April 2015

Mathematical analysis of a pharmacodynamic model without plasma concentrations to extend its applicability

scientific article published in March 2003

Mathematical modeling of the pain and progress of the first stage of nulliparous labor

scientific article published in November 2009

Measuring the predictive performance of computer-controlled infusion pumps

scientific article published in February 1992

Mixed effect modeling in analgesia trials

scientific article published in July 2008

Mixed-effects modeling of the intrinsic ventilatory depressant potency of propofol in the non-steady state

scientific article

NOTICE OF RETRACTION

scientific article published on 01 June 2009

NOTICE OF RETRACTION

scientific article published on 01 April 2009

Narrative Review of Statistical Reporting Checklists, Mandatory Statistical Editing, and Rectifying Common Problems in the Reporting of Scientific Articles

scientific article published on 26 September 2016

Neuromuscular block differentially affects immobility and cortical activation at near-minimum alveolar concentration anesthesia

scientific article published in October 2009

No evidence for the development of acute tolerance to analgesic, respiratory depressant and sedative opioid effects in humans

scientific article

Nomenclature for computer-assisted infusion devices.

scientific article

Non-steady state analysis of the pharmacokinetic interaction between propofol and remifentanil.

scientific article published in December 2002

Notice of Retraction

scientific article published on 01 December 2010

Notice of Retraction

Occam???s Razor

scientific article published on 01 June 2007

Pediatric Research and Scholarship: Another Gordian Knot?

scientific article published on 01 July 2006

Pharmacodynamic modeling of the electroencephalographic effects of flumazenil in healthy volunteers sedated with midazolam

scientific article published in November 1995

Pharmacogenomics and drug development

scientific article

Pharmacokinetic model-driven infusion of fentanyl in children

scientific article

Pharmacokinetic parameters relevant to recovery from opioids.

scientific article

Pharmacokinetic principles

Pharmacokinetic study of FFP photochemically treated with amotosalen (S-59) and UV light compared to FFP in healthy volunteers anticoagulated with warfarin

scientific article published in October 2002

Pharmacokinetic-pharmacodynamic modeling in drug development: application to the investigational opioid trefentanil

scientific article

Pharmacokinetics and Pharmacodynamics of Drugs Commonly Used in Pregnancy and Parturition

scientific article published on March 2016

Pharmacokinetics and pharmacodynamics in anesthetic drug development

scientific article published on January 1, 1998

Pharmacokinetics and pharmacodynamics of intraspinal dexmedetomidine in sheep.

scientific article published in June 1994

Pharmacokinetics and pharmacodynamics of remifentanil. II. Model application

scientific article published in January 1997

Pharmacokinetics of computer-controlled alfentanil administration in children undergoing cardiac surgery

scientific article published in November 1995

Pharmacokinetics of inhaled liposome-encapsulated fentanyl.

scientific article published on August 1995

Pharmacokinetics of intravenous dynorphin A(1-13) in opioid-naive and opioid-treated human volunteers.

scientific article published in July 1998

Pharmacokinetics of propofol in adult patients undergoing coronary revascularization. The Multicenter Study of Perioperative Ischemia Research Group.

scientific article published in June 1996

Pharmacokinetics, Pharmacodynamics, and Rational Opioid Selection ⬇️

scientific article published on January 1, 1991

Pharmacokinetics, cortisol release, and hemodynamics after intravenous and subcutaneous injection of human corticotropin-releasing factor in humans

scientific article published in November 1998

Picking safe combinations

scientific article published in December 2004

Piritramide and alfentanil display similar respiratory depressant potency.

scientific article published in November 2003

Pitfalls in chronobiology: a suggested analysis using intrathecal bupivacaine analgesia as an example

scientific article published on 4 May 2010

Plagiarism Is Ubiquitous

scientific article published in June 2016

Plagiarism is plagiarism is plagiarism

scientific article published in January 2014

Plasma concentration clamping in the rat using a computer-controlled infusion pump.

scientific article published in June 1992

Population pharmacodynamics of midazolam administered by target controlled infusion in SICU patients after CABG surgery

scientific article published in December 1998

Population pharmacokinetics of midazolam administered by target controlled infusion for sedation following coronary artery bypass grafting

scientific article published in December 1998

Prolonged alleviation of tactile allodynia by intravenous lidocaine in neuropathic rats

scientific article published in October 1995

Publication Bias, Retrospective Bias, and Reproducibility of Significant Results in Observational Studies ⬇️

scientific article published on May 1, 2012

Quantifying anesthetic drug interaction. Implications for drug dosing

scientific article published in July 1995

Remifentanil Dosing at Extremes of Body Weight

scientific article

Remifentanil versus alfentanil: comparative pharmacokinetics and pharmacodynamics in healthy adult male volunteers

scientific article published in April 1996

Retraction Notice

scientific article published on 01 April 2009

Safety of patients reason for FDA black box warning on droperidol

scientific article published in February 2004

Shadow of Doubt ⬇️

scientific article published on February 4, 2011

Shock values

scientific article

Simultaneous measurements of cardiac output by thermodilution, esophageal Doppler, and electrical impedance in anesthetized patients.

scientific article published in October 1988

Spectral entropy as an electroencephalographic measure of anesthetic drug effect: a comparison with bispectral index and processed midlatency auditory evoked response

scientific article published in July 2004

Target controlled infusions: targeting the effect site while limiting peak plasma concentration

scientific article published in November 2004

Target-Controlled Infusions: Surfing USA Redux

scientific article

Target-controlled infusions for intravenous anesthetics: surfing USA not!

scientific article published in November 2003

Tattered threads

scientific article published on 01 May 2009

Teaching application of clinical pharmacology skills using unusual observations from clozapine overdoses

scientific article published on February 2004

Thank You, Thank You, Thank You.

scientific article

Thank you, Larry Saidman!

scientific article published in December 2014

The Scott Reuben saga: one last retraction

scientific article published in March 2011

The World Federation of Societies of Anaesthesiologists, International Anesthesia Research Society, and Anesthesia & Analgesia: a shared global vision

scientific article

The complexity of recovery from anesthesia

scientific article published in September 2005

The development and validation of a dynamic model to account for the progress of labor in the assessment of pain

scientific article

The importance of dose-response in study design

scientific article published on 01 September 1999

The influence of age on propofol pharmacodynamics

scientific article published in June 1999

The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers

scientific article published in May 1998

The need for a journal policy on intrathecal, epidural, and perineural administration of non-approved drugs

scientific article published on 15 March 2010

The pharmacokinetics of propofol in children using three different data analysis approaches.

scientific article published on January 1994

The pharmacokinetics of the conopeptide contulakin-G (CGX-1160) after intrathecal administration: an analysis of data from studies in beagles

scientific article

Thiopental Pharmacodynamics I. Defining the Pseudo–Steady-state Serum Concentration–EEG Effect Relationship ⬇️

scientific article published on August 1, 1992

Threats to safety during sedation outside of the operating room and the death of Michael Jackson

scientific article published on February 2016

Truth is elusive

scientific article published on 01 July 2016

Tutorial: context-sensitive decrement times for inhaled anesthetics

scientific article published in September 2005

Two equally valid interpretations of the linear multicompartment mammillary pharmacokinetic model

scientific article published in April 1990

Unraveling the identity of benzodiazepine binding sites in rat hipppocampus and olfactory bulb

scientific article published on 01 July 2000

Urine and plasma catecholamine and cortisol concentrations after myocardial revascularization. Modulation by continuous sedation. Multicenter Study of Perioperative Ischemia (McSPI) Research Group, and the Ischemia Research and Education Foundation

scientific article published on 01 April 1997

Use of population modeling to define rational monitoring of amiodarone hepatic effects

scientific article published in April 2004

Using the time of maximum effect site concentration to combine pharmacokinetics and pharmacodynamics

scientific article published in August 2003

Validation of the alfentanil canonical univariate parameter as a measure of opioid effect on the electroencephalogram

scientific article published in October 1995

Variability of target-controlled infusion is less than the variability after bolus injection

scientific article published in March 2005

Walk a Mile in My Shoes

scientific article published on 01 August 2010

When the model does not fit the data, the model is wrong

scientific article published in April 2009

Writing Research Reports

scientific article published in January 2018

Writing successful research proposals for medical science

scientific article published on 01 June 1998

You Will Be Caught

scientific article published on 01 March 2011

β2-adrenergic receptor genotype and other variables that contribute to labor pain and progress

scientific article

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