List of works - Jiang Hualiang

A gating mechanism for Pi release governs the mRNA unwinding by eIF4AI during translation initiation

scientific article

Agonist-bound structure of the human P2Y12 receptor

scientific article

Characterization of Gain-of-Function Mutant Provides New Insights into ClpP Structure

scientific article

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

scientific article

Design and Structure-Based Study of New Potential FKBP12 Inhibitors ⬇️

scientific article published on November 1, 2003

Dopamine D1 receptor agonist and D2 receptor antagonist effects of the natural product (-)-stepholidine: molecular modeling and dynamics simulations

scientific article

Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design

scientific article

Enzymatic characterization and crystal structure analysis of the D-alanine-D-alanine ligase from Helicobacter pylori

scientific article

Enzyme-Dependent [4 + 2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4

scientific article

Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5

scientific article

Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations

scientific article

Hormone- and antibody-mediated activation of the thyrotropin receptor

scientific article published on 08 August 2022

Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease

scientific article published on 15 June 2021

Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding

scientific article

Inherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanism

scientific article (publication date: July 2009)

Malonyl-CoA: acyl carrier protein transacylase from Helicobacter pylori: Crystal structure and its interaction with acyl carrier protein

scientific article

Molecular Determinants of Magnolol Targeting Both RXRα and PPARγ ⬇️

scientific article published on November 29, 2011

Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase fromE. coli: Enzymatic characterization with crystal structure analysis

scientific article

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

scientific article

Structural Basis for Molecular Recognition at Serotonin Receptors

scientific article

Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition ⬇️

scientific article published on October 20, 2011

Structural basis for activation of the growth hormone-releasing hormone receptor

scientific article published on 15 October 2020

Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ)

scientific article

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

scientific article

Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium

scientific article

Structural basis of leukotriene B4 receptor 1 activation

scientific article published on 03 March 2022

Structural insight into substrate preference for TET-mediated oxidation

scientific article

Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex

scientific article

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

scientific article

Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease

scientific article

Structures and mechanism for the design of highly potent glucocorticoids

scientific article

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site

scientific article

Thermodynamic and structural characterization of halogen bonding in protein-ligand interactions: a case study of PDE5 and its inhibitors

scientific article

Two disparate ligand-binding sites in the human P2Y1 receptor

scientific article

List of works by Jiang Hualiang

A gating mechanism for Pi release governs the mRNA unwinding by eIF4AI during translation initiation

Agonist-bound structure of the human P2Y12 receptor

Characterization of Gain-of-Function Mutant Provides New Insights into ClpP Structure

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Design and Structure-Based Study of New Potential FKBP12 Inhibitors ⬇️

Dopamine D1 receptor agonist and D2 receptor antagonist effects of the natural product (-)-stepholidine: molecular modeling and dynamics simulations

Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design

Enzymatic characterization and crystal structure analysis of the D-alanine-D-alanine ligase from Helicobacter pylori

Enzyme-Dependent [4 + 2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4

Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5

Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations

Hormone- and antibody-mediated activation of the thyrotropin receptor

Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease

Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding

Inherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanism

Malonyl-CoA: acyl carrier protein transacylase from Helicobacter pylori: Crystal structure and its interaction with acyl carrier protein

Molecular Determinants of Magnolol Targeting Both RXRα and PPARγ ⬇️

Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase fromE. coli: Enzymatic characterization with crystal structure analysis

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

Structural Basis for Molecular Recognition at Serotonin Receptors

Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition ⬇️

Structural basis for activation of the growth hormone-releasing hormone receptor

Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ)

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium

Structural basis of leukotriene B4 receptor 1 activation

Structural insight into substrate preference for TET-mediated oxidation

Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease

Structures and mechanism for the design of highly potent glucocorticoids

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site

Thermodynamic and structural characterization of halogen bonding in protein-ligand interactions: a case study of PDE5 and its inhibitors

Two disparate ligand-binding sites in the human P2Y1 receptor