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List of works by Marnie Blewitt

A comparison of control samples for ChIP-seq of histone modifications

scientific article

A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development

scientific article

An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse

scientific article

An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse

scientific article

An in vivo model for analysis of developmental erythropoiesis and globin gene regulation

scientific article published on 17 January 2014

Analysis of Histone Modifications in Acute Myeloid Leukaemia Using Chromatin Immunoprecipitation.

scientific article published in January 2018

BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation

scientific article published on 29 March 2022

ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity

scientific article

Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming

scientific article published on 25 September 2017

Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues

scientific article published on 16 June 2020

De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development

scientific article

Development of a KDM6b shRNA conditional knock down mouse model

article

Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice

scientific article

Epigenetic regulator Smchd1 functions as a tumor suppressor

scientific article published on 26 December 2012

FSHD2- and BAMS-associated mutations confer opposing effects on SMCHD1 function

scientific article published on 10 May 2018

Function of PRC2 accessory factors in haematopoietic stem cells

Functional interdependence of BRD4 and DOT1L in MLL leukemia

scientific article published on 13 June 2016

Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells

scientific article published on 23 August 2013

Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation

scientific article published on 19 June 2015

Germline loss ofMBD4predisposes to leukaemia due to a mutagenic cascade driven by 5mC

Glimma: interactive graphics for gene expression analysis

scientific article published on 15 February 2017

HBO1 is required for the maintenance of leukaemia stem cells

scientific article published on 11 December 2019

High concordance between Illumina HiSeq2500 and NextSeq500 for reduced representation bisulfite sequencing (RRBS).

scientific article

Hippocampal neurogenesis mediates sex-specific effects of social isolation and exercise on fear extinction in adolescence

scientific article published in 2021

How the mouse got its spots

scientific article published in November 2004

Ihstone H3 lysine 9 methylation is involved not only in maintaining epigenetic silencing, but is essential for setting up gene silencing

article

Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2.

scientific article published on 2 February 2015

Long-range chromatin interactions on the inactive X and at Hox clusters are regulated by the non-canonical SMC protein Smchd1

Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects

scientific article published on 01 April 2019

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

scientific article

Metastable epialleles in mammals

scientific article

Modifiers of epigenetic reprogramming show paternal effects in the mouse.

scientific article

Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells

scientific article published on 5 May 2010

Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity

scientific article

Polycomb repressive complex 2 (PRC2) suppresses Eμ-myc lymphoma.

scientific article

Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis

scientific article

RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells

scientific article published on 02 December 2020

Reduced dosage of the modifiers of epigenetic reprogramming Dnmt1, Dnmt3L, SmcHD1 and Foxo3a has no detectable effect on mouse telomere length in vivo

scientific article

Relating SMCHD1 structure to its function in epigenetic silencing

scientific article published on 11 August 2020

Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung

scientific article

Role of SmcHD1 in establishment of epigenetic states required for the maintenance of the X-inactivated state in mice

scholarly article by Yuki Sakakibara published in August 2018

SMCHD1 is involved in de novo methylation of the DUX4-encoding D4Z4 macrosatellite

scientific article published on 01 April 2019

Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing

scientific article published on 18 May 2016

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation

scientific journal article

Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway

scientific article published on 01 November 2018

Smchd1 haploinsufficiency exacerbates the phenotype of a transgenic FSHD1 mouse model

scientific article

Smchd1 is a maternal effect gene required for genomic imprinting

scientific article published on 13 November 2020

Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation

scientific article published on 02 July 2013

Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters

scientific article published on 20 August 2018

Studying X chromosome inactivation in the single-cell genomic era

scientific article published on 20 April 2018

TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.

scientific article

The Epigenetic Regulator SMCHD1 in Development and Disease

scientific article published on 17 February 2017

The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain.

scientific article published on 8 April 2016

The first mouse mutants of D14Abb1e (Fam208a) show that it is critical for early development.

scientific article

The hinge domain of the epigenetic repressor Smchd1 adopts an unconventional homodimeric configuration

scientific article published on 05 January 2016

The polycomb repressive complex 2 governs life and death of peripheral T cells

scientific article published on 20 June 2014

The use of mouse models to study epigenetics

scientific article

Transcriptional profiling of the epigenetic regulator Smchd1.

scientific article published on 31 December 2015

Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.

scientific article published on 26 December 2013

Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal

scientific article published on 15 May 2020

Using long-read sequencing to detect imprinted DNA methylation

scientific article published on 01 May 2019

Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses

scientific article

edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens

scientific article

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