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List of works by Susan Band Horwitz

2-(m-Azidobenzoyl)taxol binds differentially to distinct β-tubulin isotypes

scientific article published on 20 September 2016

A Conversation with Susan Band Horwitz

scientific article

A Symposium in Honor of Richard G. Powell, a Long-Time Associate Editor of the Journal of Natural Products

scientific article published in October 2015

A highly epothilone B-resistant A549 cell line with mutations in tubulin that confer drug dependence

scientific article published on June 2005

A label‐free mass spectrometry method for relative quantitation of β‐tubulin isotype expression in human tumor tissue ⬇️

scientific article published on October 1, 2012

A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin.

scientific article

Activation of the steroid and xenobiotic receptor (human pregnane X receptor) by nontaxane microtubule-stabilizing agents

scientific article

Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry.

scientific article

Characterization of a human βV‐tubulin antibody and expression of this isotype in normal and malignant human tissue ⬇️

scientific article published on July 2, 2012

Correction: Exploiting MEK Inhibitor-Mediated Activation of ERα for Therapeutic Intervention in ER-Positive Ovarian Carcinoma

scientific article published on 11 March 2016

Design and Synthesis of (+)-Discodermolide–Paclitaxel Hybrids Leading to Enhanced Biological Activity ⬇️

scientific article published on August 26, 2011

Design, synthesis, and biological evaluation of new-generation taxoids

scientific article published on 09 May 2008

Design, synthesis, and biological evaluation of novel C14-C3'BzN-linked macrocyclic taxoids

scientific article published on December 2008

Design, synthesis, and biological evaluation of potent discodermolide fluorescent and photoaffinity molecular probes

scientific article published on 01 November 2005

Design, synthesis, and evaluation of analogues of (+)-14-normethyldiscodermolide.

scientific article

Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide.

scientific article

Detection of human betaV-tubulin expression in epithelial cancer cell lines by tubulin proteomics

scientific article published in December 2005

Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs

scientific article published on April 2002

Direct Analysis of Tubulin Expression in Cancer Cell Lines by Electrospray Ionization Mass Spectrometry ⬇️

scientific article published on October 21, 2003

Distinct mechanisms of taxol-induced serine phosphorylation of the 66-kDa Shc isoform in A549 and RAW 264.7 cells

scientific article

Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation.

scientific article published on March 2003

Enhancement of the therapeutic efficacy of taxol by the mitogen-activated protein kinase kinase inhibitor CI-1040 in nude mice bearing human heterotransplants

scientific article

Epothilone B enhances surface EpCAM expression in ovarian cancer Hey cells ⬇️

scientific article published on August 2, 2010

Eribulin disrupts EB1-microtubule plus-tip complex formation

scientific article

Exploiting MEK Inhibitor-Mediated Activation of ERα for Therapeutic Intervention in ER-Positive Ovarian Carcinoma ⬇️

scientific article published on February 4, 2013

Exploring the mechanisms of action of the novel microtubule inhibitor vinflunine

scientific article published on June 2008

Expression of βV-Tubulin in Secretory Cells of the Fallopian Tube Epithelium Marks Cellular Atypia

scientific article published on 3 January 2018

Gene expression and mitotic exit induced by microtubule-stabilizing drugs

scientific article published on November 2003

Germline mutations of the DNA repair pathways in uterine serous carcinoma.

scientific article published in April 2016

Hallmarks of molecular action of microtubule stabilizing agents: effects of epothilone B, ixabepilone, peloruside A, and laulimalide on microtubule conformation

scientific article

High expression of class III β-tubulin predicts good response to neoadjuvant taxane and doxorubicin/cyclophosphamide-based chemotherapy in estrogen receptor-negative breast cancer

scientific article

Highly concise routes to epothilones: the total synthesis and evaluation of epothilone 490.

scientific article published in August 2002

Identifying the semantic and textual differences between two versions of a program

Improved Dose-Response Relationship of (+)-Discodermolide-Taxol Hybrid Congeners.

scientific article

Increased levels of a unique post-translationally modified betaIVb-tubulin isotype in liver cancer

scientific article published on 21 June 2008

Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence ⬇️

scientific article published on January 1, 2011

Insights into the mechanism of microtubule stabilization by Taxol.

scholarly article

Insulin-like growth factor 2 expression modulates Taxol resistance and is a candidate biomarker for reduced disease-free survival in ovarian cancer.

scientific article

Introduction. The novel microtubule inhibitor vinflunine

scientific article published in June 2008

Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy

scientific article published on 28 October 2005

Mechanisms of Taxol resistance related to microtubules. ⬇️

scientific article

Methods in tubulin proteomics

scientific article

Nature as a remarkable chemist: a personal story of the discovery and development of Taxol

scientific article published on May 2014

Novel molecules that interact with microtubules and have functional activity similar to Taxol™ ⬇️

scientific article published on November 15, 2001

Personal recollections on the early development of taxol

scientific article published on February 2004

Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of epothilone B, in solid tumors

scientific article published in February 2004

Potentiation of taxol efficacy and by discodermolide in ovarian carcinoma xenograft-bearing mice

scientific article

Proteomics of cancer cell lines resistant to microtubule-stabilizing agents.

scientific article

Reflections on My Life with Taxol

scientific article published on 02 April 2019

Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1–dependent ⬇️

scientific article published on December 20, 2010

Stathmin/Op18 is a novel mediator of vinblastine activity

scientific article

Structural Basis of Microtubule Stabilization by Discodermolide.

scientific article published on 16 February 2017

Structural Evidence for Cooperative Microtubule Stabilization by Taxol and the Endogenous Dynamics Regulator MAP4 ⬇️

scientific article published on 06 February 2012

Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence

scientific article published on 26 June 2020

Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells

scientific article published on July 2004

Synthesis and Biological Evaluation of Novel 3'-Difluorovinyl Taxoids

scientific article

TP53 hot spot mutations in ovarian cancer: selective resistance to microtubule stabilizers in vitro and differential survival outcomes from The Cancer Genome Atlas

scientific article published on 06 May 2015

Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression

scientific article published in December 2007

Taxol Analogues Exhibit Differential Effects on Photoaffinity Labeling of β-Tubulin and the Multidrug Resistance Associated P-Glycoprotein.

scientific article published on 8 March 2018

Taxol®: The First Microtubule Stabilizing Agent

scientific article published on 9 August 2017

Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes

scientific article

The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of ixabepilone: a first in class epothilone B analogue in late-phase clinical development.

scientific article published in May 2008

The interaction between mitotic checkpoint proteins, CENP-E and BubR1, is diminished in epothilone B-resistant A549 cells

scientific article published on 15 March 2010

The microtubule stabilizing agent discodermolide is a potent inducer of accelerated cell senescence

scientific article

Tissue microarray analysis of hormonal signaling pathways in uterine carcinosarcoma

scientific article published on 06 February 2009

Total Synthesis of(–)-Epothilone B: An Extension of the Suzuki Coupling Method and Insights into Structure–Activity Relationships of the Epothilones

scientific article (publication date: 18 April 1997)

Tubulin proteomics: towards breaking the code.

scientific article

Use of the tubulin bound paclitaxel conformation for structure-based rational drug design

scientific article

Using Static Analysis to Reduce Dynamic Analysis Overhead

Using peer-led team learning to increase participation and success of under-represented groups in introductory computer science

scholarly article by Susan Band Horwitz et al published 4 March 2009 in SIGCSE bulletin

Validation of the pharmacodynamics of BMS-247550, an analogue of epothilone B, during a phase I clinical study

scientific article

Wild-type class I beta-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a beta-tubulin mutation

scientific article published on 14 September 2007

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