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List of works by Iwao Ojima

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Recent advances in tumor-targeting anticancer drug conjugates.

scientific article
Functionalized single-walled carbon nanotubes as rationally designed vehicles for tumor-targeted drug delivery.

scientific article
Mechanism-based tumor-targeting drug delivery system. Validation of efficient vitamin receptor-mediated endocytosis and drug release.

scientific article
A common pharmacophore for cytotoxic natural products that stabilize microtubules

scientific article
Characterization of the Taxol Binding Site on the Microtubule

scientific article published in Journal of Biological Chemistry
Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells

scientific article published on September 1996
Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs

scientific article published in 2012
Guided molecular missiles for tumor-targeting chemotherapy--case studies using the second-generation taxoids as warheads.

scientific article published on 31 July 2007
Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia.

scientific article
Transition Metal-Catalyzed Carbocyclizations in Organic Synthesis

article
Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD).

scientific article
Targeting FtsZ for antituberculosis drug discovery: noncytotoxic taxanes as novel antituberculosis agents

scientific article published on January 2006
Syntheses and structure-activity relationships of taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III.

scientific article published on January 1997
Design, synthesis, and biological evaluation of new-generation taxoids

scientific article published on 09 May 2008
Novel trisubstituted benzimidazoles, targeting Mtb FtsZ, as a new class of antitubercular agents

scientific article
Use of the tubulin bound paclitaxel conformation for structure-based rational drug design

scientific article
Syntheses and evaluation of novel fatty acid-second-generation taxoid conjugates as promising anticancer agents

scientific article published on 18 November 2005
Chemistry and chemical biology of taxane anticancer agents.

scientific article
New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells

scientific article published on 14 July 2010
Tumor-Specific Novel Taxoid−Monoclonal Antibody Conjugates

scientific article published on 01 December 2002
Overcoming multidrug resistance in taxane chemotherapy

scientific article
New and efficient approaches to the semisynthesis of taxol and its C-13 side chain analogs by means of β-lactam synthon method

Synthesis and structure-activity relationships of new second-generation taxoids

scientific article published on 01 December 1999
Discovery of anti-TB agents that target the cell-division protein FtsZ.

scientific article
Antithrombotic agents: from RGD to peptide mimetics.

scientific article published on April 1995
Effects of orally active taxanes on P-glycoprotein modulation and colon and breast carcinoma drug resistance

scientific article
Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids

scientific article published on 23 June 2015
Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein.

scientific article
Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus

scientific journal article
FtsZ: a novel target for tuberculosis drug discovery

scientific article published on January 2007
A highly epothilone B-resistant A549 cell line with mutations in tubulin that confer drug dependence

scientific article published on June 2005
Exploration of fluorine chemistry at the multidisciplinary interface of chemistry and biology.

scientific article published on 06 May 2013
Poly(2-oxazoline) based micelles with high capacity for 3rd generation taxoids: preparation, in vitro and in vivo evaluation

scientific article published on 26 February 2015
Recent advances in the new generation taxane anticancer agents.

scientific article published on March 2005
Therapeutic potential of FtsZ inhibition: a patent perspective

scientific article published on 18 March 2011
SAR studies on trisubstituted benzimidazoles as inhibitors of Mtb FtsZ for the development of novel antitubercular agents

scientific article
Anti-proliferative activity of a new class of taxanes (14β-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells

scientific article published on 01 September 1997
Prostate Cancer Stem Cell-Targeted Efficacy of a New-Generation Taxoid, SBT-1214 and Novel Polyenolic Zinc-Binding Curcuminoid, CMC2.24

scientific article published on September 24, 2013
Taxane anticancer agents: a patent perspective

scientific article published on 10 December 2015
Tumor-targeting drug delivery of new-generation taxoids

scientific article published on January 2012
Characterizing septum inhibition in Mycobacterium tuberculosis for novel drug discovery

scientific article published on 13 May 2008
Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023.

scientific article published on 27 January 2004
Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells

scientific article
Recent advances in the study of the bioactive conformation of taxol

scientific article
Antitumour activity of novel taxanes that act at the same time as cytotoxic agents and P-glycoprotein inhibitors

scientific article published on December 2000
Identification of the Domains of Photoincorporation of the 3‘- and 7-Benzophenone Analogues of Taxol in the Carboxyl-Terminal Half of Murine mdr1b P-glycoprotein

scientific article published on August 11, 1998
Synthesis and Structure−Activity Relationships of Nonaromatic Taxoids: Effects of Alkyl and Alkenyl Ester Groups on Cytotoxicity

scientific article published on 01 January 1997
New taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells

scientific article published on 01 January 1998
Design, synthesis, and biological evaluations of tumor-targeting dual-warhead conjugates for a taxoid-camptothecin combination chemotherapy

scientific article
Antitumor efficacy of taxane liposomes on a human ovarian tumor xenograft in nude athymic mice.

scientific article published on December 1995

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