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List of works by Irun Cohen

A conjugate vaccine composed of a heat shock protein 60 T-cell epitope peptide (p458) and Neisseria meningitidis type B capsular polysaccharide

scientific article published on 27 June 2006

A structurally altered D,L-amino acid TCRalpha transmembrane peptide interacts with the TCRalpha and inhibits T-cell activation in vitro and in an animal model.

scientific article published on 9 February 2007

A systems immunology approach to the host-tumor interaction: large-scale patterns of natural autoantibodies distinguish healthy and tumor-bearing mice.

scientific article

An antibody profile of systemic lupus erythematosus detected by antigen microarray

scientific article published on 26 February 2010

Analyses of antigen dependency networks unveil immune system reorganization between birth and adulthood ⬇️

scientific article published on March 1, 2011

Angiogenesis-inflammation cross-talk: vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization

scientific journal article

Anti-ergotypic T cells in naïve rats

scientific article published on 01 May 2005

Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis

scientific article

Autoimmune encephalomyelitis and uveitis induced by T cell immunity to self beta-synuclein

scientific article published on January 2003

Bacillus Calmette-Guérin (BCG) therapy lowers the incidence of Alzheimer's disease in bladder cancer patients

scientific article published on 07 November 2019

Beta-lactam antibiotics modulate T-cell functions and gene expression via covalent binding to cellular albumin

scientific article published on 4 February 2013

Characterization of the interacting domain of the HIV-1 fusion peptide with the transmembrane domain of the T-cell receptor

scientific article

Chimeric vaccine composed of viral peptide and mammalian heat-shock protein 60 peptide protects against West Nile virus challenge.

scientific article published on 16 March 2010

Chronic rejection of a lung transplant is characterized by a profile of specific autoantibodies

scientific article published on 26 February 2010

Cluster analysis of human autoantibody reactivities in health and in type 1 diabetes mellitus: a bio-informatic approach to immune complexity

scientific article published in August 2003

Cutting edge: T cells respond to lipopolysaccharide innately via TLR4 signaling

scientific article published on 01 July 2007

D-enantiomer peptide of the TCRalpha transmembrane domain inhibits T-cell activation in vitro and in vivo.

scientific article

DNA Fragments of the Human 60-kDa Heat Shock Protein (HSP60) Vaccinate Against Adjuvant Arthritis: Identification of a Regulatory HSP60 Peptide ⬇️

scientific article published on 01 October 2003

DNA Vaccination with Heat Shock Protein 70 Protects (NZB x NZW)F1 Mice from Systemic Lupus Erythematosus

scientific article published on 13 January 2020

DNA vaccination with CD25 protects rats from adjuvant arthritis and induces an antiergotypic response

scientific article published on March 2004

DNA vaccination with heat shock protein 60 inhibits cyclophosphamide-accelerated diabetes

scientific article published on November 2002

DNA vaccine encoding heat shock protein 90 protects from murine lupus

scientific article published on 22 June 2020

Ectopic PDX-1 expression in liver ameliorates type 1 diabetes

scientific article published on 23 March 2007

Emergent dynamics of thymocyte development and lineage determination

scientific article (publication date: 26 January 2007)

Epstein-Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti-DNA.

scientific article published on February 2014

Functional immunomics: microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes.

scholarly article

G-CSF enhances the adhesion of encephalitogenic T cells to extracellular matrix components: a possible mechanism for exacerbation of multiple sclerosis

scientific article published on 4 January 2006

Guanine polynucleotides are self-antigens for human natural autoantibodies and are significantly reduced in the human genome

scientific article published on 29 July 2015

HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation

scientific article

HSP60 as a target of anti-ergotypic regulatory T cells

scientific journal article

Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway

scientific article

Heat shock protein 60 activates cytokine-associated negative regulator suppressor of cytokine signaling 3 in T cells: effects on signaling, chemotaxis, and inflammation

scientific article published on 01 July 2005

Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling

scientific article published on 8 June 2006

Heat shock protein 60 enhances CD4+CD25+ regulatory T cell function via innate TLR2 signaling.

scientific article published on 7 May 2018

Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines

scientific article published on 01 March 2005

Heat shock protein 60, via MyD88 innate signaling, protects B cells from apoptosis, spontaneous and induced

scientific article published on 26 June 2009

Heat shock proteins as endogenous adjuvants in sterile and septic inflammation

scientific article

Heparin-disaccharide affects T cells: inhibition of NF-kappaB activation, cell migration, and modulation of intracellular signaling

scientific article published on 12 March 2004

IL-10 mediates resistance to adoptive transfer experimental autoimmune encephalomyelitis in MyD88(-/-) mice

scientific article

Identification of aldolase as a target antigen in Alzheimer's disease

scientific article published in September 2005

Identification of alpha-tropomyosin as a target self-antigen in Behçet's syndrome

scientific article

Individual and meta-immune networks.

scientific article published on 15 March 2013

Induction of IgG3 to LPS via Toll-like receptor 4 co-stimulation

scientific article

Inhibition of adjuvant arthritis by a DNA vaccine encoding human heat shock protein 60

scientific article published on 01 September 2002

Inhibition of adjuvant-induced arthritis by DNA vaccination with the 70-kd or the 90-kd human heat-shock protein: immune cross-regulation with the 60-kd heat-shock protein

scientific article published on 01 November 2004

Integrative analysis correlates donor transcripts to recipient autoantibodies in primary graft dysfunction after lung transplantation ⬇️

scientific article published on November 11, 2010

Knock-out of the histidine decarboxylase gene modifies the repertoire of natural autoantibodies.

scientific article published in June 2004

Monoclonal antibody to a DNA-binding domain of p53 mimics charge structure of DNA: anti-idiotypes to the anti-p53 antibody are anti-DNA.

scientific article

Mouse dendritic cells pulsed with capsular polysaccharide induce resistance to lethal pneumococcal challenge: roles of T cells and B cells

scientific article

Network theory analysis of antibody-antigen reactivity data: the immune trees at birth and adulthood

scientific article

Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics

scientific article published on March 2007

Organization of the autoantibody repertoire in healthy newborns and adults revealed by system level informatics of antigen microarray data.

scientific article

Pemphigus vulgaris is characterized by low IgG reactivities to specific self-antigens along with high IgG reactivity to desmoglein 3

scientific article published on 01 November 2014

Peptide p277 of HSP60 signals T cells: inhibition of inflammatory chemotaxis

scientific article published on 07 August 2006

Pillars Article: The Rapid Isolation of Clonable Antigen-specific T Lymphocyte Lines Capable of Mediating Autoimmune Encephalomyelitis. Eur J Immunol. 1981.11: 195-199

scientific article published in May 2017

Pneumococcal capsular polysaccharide is immunogenic when present on the surface of macrophages and dendritic cells: TLR4 signaling induced by a conjugate vaccine or by lipopolysaccharide is conducive.

scientific article published on February 2008

Prevalence of autoantibodies to the p53 protein in autoimmune hepatitis

scientific article published on 01 December 2002

Proteins and their derived peptides as carriers in a conjugate vaccine for Streptococcus pneumoniae: self-heat shock protein 60 and tetanus toxoid

scientific article published in June 2003

Reactive animation: from piecemeal experimentation to reactive biological systems

scientific article published on 19 January 2011

Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+ and CD8+ T cells: analysis using depleting antibodies

scientific article published in August 2004

Regulatory T cells and immune computation

scientific article published in April 2008

Response to "Interaction between HIV gp41 fusion peptide and T cell receptor: putting the puzzle pieces back together".

scientific article published in June 2007

Self HSP60 peptide serves as an immunogenic carrier for a CTL epitope against persistence of murine cytomegalovirus in the salivary gland

scientific article published on 01 May 2005

Signaling via TLR2 and TLR4 Directly Down-Regulates T Cell Effector Functions: The Regulatory Face of Danger Signals

scientific article published on 25 July 2013

Simplicity belies a complex system: a response to the minimal model of immunity of Langman and Cohn

scientific article

Split immunity: immune inhibition of rat gliomas by subcutaneous exposure to unmodified live tumor cells.

scientific article published on 12 October 2011

T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences

scientific article published on 21 July 2017

T cell vaccination benefits relapsing progressive multiple sclerosis patients: a randomized, double-blind clinical trial

scientific article

T cell vaccination induces the elimination of EAE effector T cells: analysis using GFP-transduced, encephalitogenic T cells

scientific article published on 26 June 2010

T cells and autoantibodies to human HSP70 in type 1 diabetes in children

scientific article published on 01 June 2003

T cells respond to heat shock protein 60 via TLR2: activation of adhesion and inhibition of chemokine receptors

scientific article published on 17 June 2003

T-cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif

scientific article

T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity

scientific article

T-cell seeding: neonatal transfer of anti-myelin basic protein T-cell lines renders Fischer rats susceptible later in life to the active induction of experimental autoimmune encephalitis

scientific article

T-cell vaccination against anti-CD4 autoimmunity in HIV-1 infected patients

scientific article published in December 2004

T-cell vaccination against anti-CD4 autoimmunity in HIV-1 subtypes B and C-infected patients--an extended open trial

scientific article published on 01 March 2005

The evolution of universal adaptations of life is driven by universal properties of matter: energy, entropy, and interaction

scientific article published on 18 June 2020

The evolution of universal adaptations of life is driven by universal properties of matter: energy, entropy, and interaction

scientific article published in 2020

The heuristics of biologic theory: the case of self-nonself discrimination

scientific article published on 01 May 2003

The natural autoantibody repertoire and autoimmune disease

scientific article published on June 2004

The natural autoantibody repertoire in newborns and adults: a current overview

scientific article published on January 2012

Toll-like receptors and their ligands control mesenchymal stem cell functions

scientific article

Toward rigorous comprehension of biological complexity: modeling, execution, and visualization of thymic T-cell maturation

scientific article

Tregs in T cell vaccination: exploring the regulation of regulation

scientific article

Tumor-associated and disease-associated autoantibody repertoires in healthy colostrum and maternal and newborn cord sera

scientific article published on 27 April 2015

Unique gene expression patterns in human T-cell lines generated from multiple sclerosis patients by stimulation with a synthetic MOG peptide

scientific article published on September 2005

Updating Darwin: Information and entropy drive the evolution of life

scientific article (publication date: 2016)

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