Search filters

List of works by Lynne E. Maquat

"Alu"strious long ncRNAs and their role in shortening mRNA half-lives

scientific article published on 15 June 2011

'Black sheep' that don't leave the double-stranded RNA-binding domain fold

scientific article

3'READS+RIP defines differential Staufen1 binding to alternative 3'UTR isoforms and reveals structures and sequence motifs influencing binding and polysome association

scientific article published on 12 August 2020

A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsensecontaining mRNAs in mammalian cells ⬇️

scientific article published on August 18, 1998

A post-translational regulatory switch on UPF1 controls targeted mRNA degradation

scientific article

A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance ⬇️

scientific article (publication date: June 1998)

A yeast model of FUS/TLS-dependent cytotoxicity

scientific article

Affinity purification of long noncoding RNA-protein complexes from formaldehyde cross-linked mammalian cells

scientific article published on January 2015

An enemy within: fly reconnaissance deploys an endonuclease to destroy nonsense-containing mRNA.

scientific article

Applying nonsense-mediated mRNA decay research to the clinic: progress and challenges

scientific article published on 16 June 2006

At Least One Intron Is Required for the Nonsense-Mediated Decay of Triosephosphate Isomerase mRNA: a Possible Link between Nuclear Splicing and Cytoplasmic Translation ⬇️

scientific article published on September 1, 1998

Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics

scientific article

Beta -Globin mRNA decay in erythroid cells: UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon

scientific article

Beyond Transcription: Roles of Transcription Factors in Pre-mRNA Splicing.

scientific article published on 18 December 2017

Biochemical analysis of long non-coding RNA-containing ribonucleoprotein complexes

scientific article published on 10 July 2012

CARMing down the SINEs of anarchy: two paths to freedom from paraspeckle detention

scientific article

CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells

scientific article published on 25 September 2005

Cap-binding protein 1-mediated and eukaryotic translation initiation factor 4E-mediated pioneer rounds of translation in yeast

scientific article

Chapter 9. Studying nonsense-mediated mRNA decay in mammalian cells

scientific article

Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.

scientific article

Control of myogenesis by rodent SINE-containing lncRNAs

scientific article published on 4 April 2013

Coupling pre-mRNA splicing and 3' end formation to mRNA export: alternative ways to punch the nuclear export clock

scientific article published on March 2016

Crystal structure of a poly(rA) staggered zipper at acidic pH: evidence that adenine N1 protonation mediates parallel double helix formation

scientific article published on 10 June 2016

Defective secretory-protein mRNAs take the RAPP.

scientific article published on 3 March 2014

Defining nonsense-mediated mRNA decay intermediates in human cells

scientific article published on 19 December 2018

Distinct mechanisms obviate the potentially toxic effects of inverted-repeat Alu elements on cellular RNA metabolism

scientific article

Dodging two bullets with one dsRNA-binding protein

scientific article published on 13 December 2013

Efficiency of the pioneer round of translation affects the cellular site of nonsense-mediated mRNA decay

scientific article

Erratum: Regulation of cytoplasmic mRNA decay

scholarly article published in Nature Reviews Genetics

Eukaryotic antisense ahead of its time

scientific article published on 24 February 2016

Evaluating the susceptibility of AGO2-loaded microRNAs to degradation by nucleases in vitro

scientific article published on 17 May 2018

Evidence for convergent evolution of SINE-directed Staufen-mediated mRNA decay

scientific article published on 16 January 2018

Evidence that poly(A) binding protein C1 binds nuclear pre-mRNA poly(A) tails

scientific article

Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA

scientific article

Gene expression networks: competing mRNA decay pathways in mammalian cells

scientific article published on December 2009

Human beta-globin mRNAs that harbor a nonsense codon are degraded in murine erythroid tissues to intermediates lacking regions of exon I or exons I and II that have a cap-like structure at the 5' termini ⬇️

scientific article published on September 1, 1992

Identifying Cellular Nonsense-Mediated mRNA Decay (NMD) Targets: Immunoprecipitation of Phosphorylated UPF1 Followed by RNA Sequencing (p-UPF1 RIP-Seq).

scientific article published in January 2018

Immunopurification and analysis of protein and RNA components of mRNP in mammalian cells

scientific article published in January 2004

In vitro analysis of the Escherichia coli RNA polymerase interaction with wild-type and mutant lactose promoters ⬇️

scientific article published on November 15, 1978

Influence of A-T content on the fractionation of DNA restriction fragments by RPC-5 column chromatography ⬇️

scientific article published on June 25, 1979

Introduction-RNA: From Single Molecules to Medicine

scientific article published on 01 April 2018

Intron function in the nonsense-mediated decay of β-globin mRNA: Indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm ⬇️

scientific article published on July 1, 1998

Leveraging Rules of Nonsense-Mediated mRNA Decay for Genome Engineering and Personalized Medicine

scientific article published on June 2016

Loss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decay

scientific article published on 08 January 2021

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

scientific article

Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells

scientific article

Mobile DNA: an evolving field

scientific article published on 5 June 2014

Molecular autopsy provides evidence for widespread ribosome-phased mRNA fragmentation.

scientific article

Molecular biology. Skiing toward nonstop mRNA decay

scientific article published on 01 March 2002

NASty effects on fibrillin pre-mRNA splicing: another case of ESE does it, but proposals for translation-dependent splice site choice live on.

scientific article

NCBP3: A Multifaceted Adaptive Regulator of Gene Expression

scientific article published on 05 October 2020

NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome

scientific article published on 16 November 2021

NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA

scientific article

NMD-degradome sequencing reveals ribosome-bound intermediates with 3'-end non-templated nucleotides

scientific article published on 01 October 2018

New gene expression pipelines gush lncRNAs

scientific article

Nonsense codons in human beta-globin mRNA result in the production of mRNA degradation products ⬇️

scientific article published on March 1, 1992

Nonsense-mediated decay: assaying for effects on selenoprotein mRNAs

scientific article published in January 2002

Nonsense-mediated mRNA Decay and Cancer

scientific article published on 6 November 2017

Nonsense-mediated mRNA decay

scientific article published on 01 March 2002

Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question

scientific article

Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities

scientific article (publication date: September 2003)

Nonsense-mediated mRNA decay in mammals

scientific article

Organizing principles of mammalian nonsense-mediated mRNA decay

scientific article

Preface

Publisher Correction: NMD-degradome sequencing reveals ribosome-bound intermediates with 3'-end non-templated nucleotides

scientific article published on 01 November 2018

Publisher Correction: Quality and quantity control of gene expression by nonsense-mediated mRNA decay

scientific article published on 01 June 2019

Quality and quantity control of gene expression by nonsense-mediated mRNA decay

scientific article published on 01 July 2019

Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function

scientific article

Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression

scientific article

RNA Processing and Human Disorders

RNA turnover in eukaryotes: analysis of specialized and quality control RNA decay pathways. Preface

scientific article published on 01 January 2008

RNA turnover in eukaryotes: nucleases, pathways and analysis of mRNA decay. Preface

scientific article published on 01 January 2008

RNA-protein interactions: insight into gene function

scientific article published on 01 February 2002

RNA. A TRICK'n way to see the pioneer round of translation

scientific article published on 01 March 2015

Re-capping the message

scientific article

Regulation of cytoplasmic mRNA decay ⬇️

scientific article published on March 6, 2012

Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay

scientific article published on 28 April 2008

Remodeling of the pioneer translation initiation complex involves translation and the karyopherin importin beta

scientific article

Retrotransposons as regulators of gene expression

scientific article

Rules that govern UPF1 binding to mRNA 3' UTRs

scientific article published on 12 February 2013

SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs

scientific article published on 18 December 2008

STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown

scientific article published on July 2013

Selenium Deficiency Reduces the Abundance of mRNA for Se-Dependent Glutathione Peroxidase 1 by a UGA-Dependent Mechanism Likely To Be Nonsense Codon-Mediated Decay of Cytoplasmic mRNA ⬇️

scientific article published on May 1, 1998

Sequences Within the Last Intron function in RNA 3'-End Formation in Cultured Cells ⬇️

scientific article published on June 1, 1993

Short interspersed nuclear element (SINE)-mediated post-transcriptional effects on human and mouse gene expression: SINE-UP for active duty

scientific article published on 10 February 2020

Staufen-mediated mRNA decay

scientific article published on 16 May 2013

Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay

scientific article

Staufen1 regulates diverse classes of mammalian transcripts

scientific article published on 17 May 2007

Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity

scientific article published on 20 December 2012

Telomeric RNAs as a novel player in telomeric integrity

scientific article

Temporal and spatial characterization of nonsense-mediated mRNA decay

scientific article published on 21 February 2013

The amazing web of post-transcriptional gene control: the sum of small changes can make for significant consequences

scientific article

The dharma of nonsense-mediated mRNA decay in mammalian cells

scientific article

The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling

scientific article

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells

scientific article

The multiple lives of NMD factors: balancing roles in gene and genome regulation

scientific article published on September 2008

The nuclear cap-binding complex as choreographer of gene transcription and pre-mRNA processing

scientific article published on 01 September 2020

The pioneer round of translation: features and functions

scientific article

The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex

scientific article

The presence of an intron within the rat gene for selenium-dependent glutathione peroxidase 1 is not required to protect nuclear RNA from UGA-mediated decay ⬇️

scientific article published on December 1, 1997

Transcriptional Coactivator PGC-1α Binding to Newly Synthesized RNA via CBP80: A Nexus for Co- and Posttranscriptional Gene Regulation

scientific article published on 15 April 2020

Transcriptional coactivator PGC-1α contains a novel CBP80-binding motif that orchestrates efficient target gene expression.

scientific article published on 13 April 2018

UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps

scientific article published on 5 August 2010

UPF1 helicase promotes TSN-mediated miRNA decay.

scientific article

UPF1 learns to relax and unwind

scientific article published on 01 March 2011

UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond

scientific article published on 17 January 2019

Unstable β-globin mRNA in mRNA-deficient β0 thalassemia ⬇️

scientific article published on 01 December 1981

Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay

scientific article

Viral subversion of nonsense-mediated mRNA decay

scientific article published on 22 July 2020

eIF4G is required for the pioneer round of translation in mammalian cells

scientific article

lac Promoter mutation Pr115 generates a new transcription initiation point ⬇️

scientific article published on May 25, 1980

mRNA-mRNA duplexes that autoelicit Staufen1-mediated mRNA decay

scientific article published on 22 September 2013

Paulina is supported by:

About Paulina

Help