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List of works by Zoi Lygerou

<i>Ιn vivo</i> imaging of DNA-bound minichromosome maintenance complex in embryonic mouse cortex

scientific article published on 19 December 2020

A Custom Ultra-Low-Cost 3D Bioprinter Supports Cell Growth and Differentiation

scientific article published on 04 November 2020

Analysis of Protein Kinetics Using Fluorescence Recovery After Photobleaching (FRAP).

scientific article

CK1δ restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1α/ARNT complex formation

scientific article

CRL4Cdt2: Coupling Genome Stability to Ubiquitination

scientific article published on 07 February 2020

Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines

scientific article published on August 2004

Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin

scientific article

Cdt1 interactions in the licensing process: a model for dynamic spatiotemporal control of licensing

scientific article

Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs

scientific article

Cell cycle-dependent subcellular translocation of the human DNA licensing inhibitor geminin.

scientific article

Chromatin and Nuclear Architecture: Shaping DNA Replication in 3D

scientific article published on 23 July 2020

Concise Review: Geminin-A Tale of Two Tails: DNA Replication and Transcriptional/Epigenetic Regulation in Stem Cells.

scientific article published on 11 November 2016

Control of DNA replication licensing in a cell cycle

scientific article

Control over DNA replication in time and space

scientific article published on 25 July 2012

Controlling centriole numbers: Geminin family members as master regulators of centriole amplification and multiciliogenesis.

scientific article

Cortical Development and Brain Malformations: Insights From the Differential Regulation of Early Events of DNA Replication

DNA replication in the fission yeast: robustness in the face of uncertainty

scientific article published on October 2006

Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior

scientific article

Differential geminin requirement for proliferation of thymocytes and mature T cells

scientific article

Direct binding of Cdt2 to PCNA is important for targeting the CRL4 E3 ligase activity to Cdt1

scientific article published on 31 December 2018

Dynamic recruitment of licensing factor Cdt1 to sites of DNA damage

scientific article

EasyFRAP-web: a web-based tool for the analysis of fluorescence recovery after photobleaching data.

scientific article published in July 2018

Expression of α-Defensins, CD20+ B-lymphocytes, and Intraepithelial CD3+ T-lymphocytes in the Intestinal Mucosa of Patients with Liver Cirrhosis: Emerging Mediators of Intestinal Barrier Function

scientific article published on 07 June 2018

GemC1 controls multiciliogenesis in the airway epithelium

scientific journal article

GemC1 governs multiciliogenesis through direct interaction with and transcriptional regulation of p73

scientific article published on 03 June 2019

GemC1 is a critical switch for neural stem cell generation in the postnatal brain

scientific article published on 22 July 2019

Geminin Participates in Differentiation Decisions of Adult Neural Stem Cells Transplanted in the Hemiparkinsonian Mouse Brain

scientific article published on 30 May 2017

Geminin ablation in vivo enhances tumorigenesis through increased genomic instability

scientific article published on 21 August 2018

Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI/SNF subunit Brahma

scientific article published on 29 January 2007

Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors.

scientific article published on January 2015

Geminin regulates cortical progenitor proliferation and differentiation

scientific article published in August 2011

How a radial glial cell decides to become a multiciliated ependymal cell

scientific article published on 7 February 2017

IPP Complex Reinforces Adhesion by Relaying Tension-Dependent Signals to Inhibit Integrin Turnover.

scientific article published on 12 July 2016

Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression

scientific article

In silico analysis of DNA re-replication across a complete genome reveals cell-to-cell heterogeneity and genome plasticity

scientific article published on 28 January 2021

Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis

scientific article published on 3 December 2015

Inference of protein kinetics by stochastic modeling and simulation of fluorescence recovery after photobleaching experiments

scientific article published on 30 September 2014

Integrin-Linked-Kinase Overexpression Is Implicated in Mechanisms of Genomic Instability in Human Colorectal Cancer

scientific article published on 03 June 2020

Integrin-linked kinase (ILK) regulates KRAS, IPP complex and Ras suppressor-1 (RSU1) promoting lung adenocarcinoma progression and poor survival

scientific article published on 22 June 2020

Life without geminin

scientific article

Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche

scientific article published on 22 September 2015

Mcidas and GemC1/Lynkeas specify embryonic radial glial cells

scientific article published on 27 April 2016

Mismatch repair regulates Cdt1 after UV damage.

scientific article published on 20 April 2017

Multi-step loading of human minichromosome maintenance proteins in live human cells

scientific article published on 24 October 2013

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.

scientific article published on 16 March 2018

Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional contro

scientific article published on October 2004

Proteolysis of DNA replication licensing factor Cdt1 in S-phase is performed independently of geminin through its N-terminal region

scientific article

Reduced Geminin levels promote cellular senescence

scientific article published on 8 November 2012

Replication Licensing Aberrations, Replication Stress, and Genomic Instability

scientific article published on 01 May 2019

T cell proliferation and homeostasis: an emerging role for the cell cycle inhibitor geminin

scientific article published on January 2011

The Geminin and Idas Coiled Coils Preferentially Form a Heterodimer That Inhibits Geminin Function in DNA Replication Licensing

scientific article

The Licensing Factor Cdt1 Links Cell Cycle Progression to the DNA Damage Response

scientific article published on 01 May 2020

The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins

scientific article published on 31 October 2015

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

scientific article

Visualizing the dynamics of histone variants in the S-phase nucleus

article

Whole transcriptome data analysis of mouse embryonic hematopoietic stem and progenitor cells that lack Geminin expression

scientific article

easyFRAP: an interactive, easy-to-use tool for qualitative and quantitative analysis of FRAP data.

scientific article

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