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List of works by Thomas Kilduff

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The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

scientific article published in January 1998
The hypocretin/orexin ligand-receptor system: implications for sleep and sleep disorders.

scientific article published in August 2000
Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response

scientific article published on 01 December 2004
A role for cryptochromes in sleep regulation

scientific article
Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice.

scientific article published on July 2011
Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor.

scientific article
Identification of a population of sleep-active cerebral cortex neurons

scientific article
Selective loss of GABA(B) receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture.

scholarly article
Differential increase in the expression of heat shock protein family members during sleep deprivation and during sleep.

scientific article published on January 2003
Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor.

scientific article
A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight.

scientific article published on 29 May 2012
Gene expression in the rat brain during sleep deprivation and recovery sleep: an Affymetrix GeneChip study.

scientific article published on 28 October 2005
Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone

scientific article
Activation of cortical interneurons during sleep: an anatomical link to homeostatic sleep regulation?

scientific article
Circadian and light-induced expression of immediate early gene mRNAs in the rat suprachiasmatic nucleus.

scientific article published in October 1992
Immune response gene expression increases in the aging murine hippocampus.

scientific article
GABA(B) receptor-mediated modulation of hypocretin/orexin neurones in mouse hypothalamus.

scientific article published on 20 April 2006
Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics.

scientific article
GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions

scientific article published on 01 February 1995
Region-specific changes in immediate early gene expression in response to sleep deprivation and recovery sleep in the mouse brain.

scientific article published in January 2003
Mapping of the mRNAs for the hypocretin/orexin and melanin-concentrating hormone receptors: networks of overlapping peptide systems.

scientific article
The relationship of local cerebral glucose utilization to optical density ratios.

scientific article published in March 1983
Light-induced gene expression in the suprachiasmatic nucleus of young and aging rats

scientific article published on 01 September 1993
Pharmacology of basimglurant (RO4917523, RG7090), a unique metabotropic glutamate receptor 5 negative allosteric modulator in clinical development for depression

scientific article
Age-related decline in hypocretin (orexin) receptor 2 messenger RNA levels in the mouse brain.

scientific article published in November 2002
Longitudinal analysis of the electroencephalogram and sleep phenotype in the R6/2 mouse model of Huntington's disease.

scientific article published in July 2013
Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

scientific article published on March 2013
Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia.

scientific article
The Neurobiology of Sleep and Wakefulness

scientific article
C-fos mRNA increases in the ground squirrel suprachiasmatic nucleus during arousal from hibernation.

scientific article
Developmental changes in nicotinic receptor mRNAs and responses to nicotine in the suprachiasmatic nucleus and other brain regions.

scientific article published in March 1999
Nicotine and nicotinic receptors in the circadian system.

scientific article published in February 1998
Nicotine administration differentially affects gene expression in the maternal and fetal circadian clock

scientific article published on 01 January 1995
Cortical nNOS neurons co-express the NK1 receptor and are depolarized by Substance P in multiple mammalian species.

scientific article
Characterization of the Circadian System of NGFI-A and NGFI-A/NGFI-B Deficient Mice

scientific article published on August 1, 1998
Understanding the sleep-wake cycle: sleep, insomnia, and the orexin system.

scientific article published on January 2013
Influence of Inhibitory Serotonergic Inputs to Orexin/Hypocretin Neurons on the Diurnal Rhythm of Sleep and Wakefulness

scientific article published on September 1, 2013
The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats

scientific article published on 31 January 2014
Brain dopamine receptor levels elevated in canine narcolepsy

scientific article published on 01 January 1987
Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain

scientific article
Ontogeny of photic-induced c-fos mRNA expression in rat suprachiasmatic nuclei

scientific article published on December 20, 1994
Evidence for excessive sleepiness in canine narcoleptics

scientific article published on 01 November 1986
Daily variation of CNS gene expression in nocturnal vs. diurnal rodents and in the developing rat brain.

scientific article published in August 1997
Quantitative Electroencephalographic Analysis Provides an Early-Stage Indicator of Disease Onset and Progression in the zQ175 Knock-In Mouse Model of Huntington's Disease

scientific article
Homeostatic sleep pressure is the primary factor for activation of cortical nNOS/NK1 neurons

scientific article
New developments in sleep research: molecular genetics, gene expression, and systems neurobiology

scientific article
Hypocretin/orexin: maintenance of wakefulness and a multiplicity of other roles.

scientific article
Narcolepsy without unique MHC class II antigen association: studies in the canine model

scientific article published on 01 May 1989
Gene expression in the rat cerebral cortex: comparison of recovery sleep and hypnotic-induced sleep

scientific journal article
Challenges in the development of therapeutics for narcolepsy

scientific article published on 22 December 2015

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