List of works by Dmitry I. Gabrilovich

"Only a Life Lived for Others Is Worth Living": redox signaling by oxygenated phospholipids in cell fate decisions

journal article published in 2018

"Redox lipidomics technology: Looking for a needle in a haystack"

scientific article published on 27 March 2019

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

scientific article published oln 16 November 2016

A Bayesian pick-the-winner design in a randomized phase II clinical trial

scientific article published on 7 July 2017

A neuronal network of mitochondrial dynamics regulates metastasis

scientific article

A novel inhibitor of HSP70 induces mitochondrial toxicity and immune cell recruitment in tumors

scientific article published on 06 October 2020

Abstract 2103: NETs promote tumor resistance to anthracyclines

scholarly article

Activation of dendritic cells via inhibition of Jak2/STAT3 signaling

scientific article published on October 2005

Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations.

scientific article

All Myeloid-Derived Suppressor Cells Are Not Created Equal: How Gender Inequality Influences These Cells and Affects Cancer Therapy

scientific article published on 01 August 2020

All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination.

scientific article published on August 2003

All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients

scientific article

Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

scientific article

Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.

scientific article

Antibody-mediated blockade of phosphatidylserine enhances the anti-tumor activity of targeted therapy and immune checkpoint inhibitors by affecting myeloid and lymphocyte populations in the tumor microenvironment

article published in 2014

Antigen-specific CD4(+) T cells regulate function of myeloid-derived suppressor cells in cancer via retrograde MHC class II signaling

scientific article

Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species.

scientific article

Applying pressure on macrophages

scientific article

Autophagy induced by conventional chemotherapy mediates tumor cell sensitivity to immunotherapy

scientific article

BRAF Targeting Sensitizes Resistant Melanoma to Cytotoxic T Cells

scientific article published on 14 February 2019

BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells

scientific article published on 01 August 2020

Bone marrow PMN-MDSCs and neutrophils are functionally similar in protection of multiple myeloma from chemotherapy

scientific article published on 27 November 2015

CD38+ M-MDSC expansion characterizes a subset of advanced colorectal cancer patients.

scientific article published on 22 March 2018

CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation

scientific article published on February 2016

COX-1-derived thromboxane A2 plays an essential role in early B-cell development via regulation of JAK/STAT5 signaling in mouse

scientific article published on 16 July 2014

Can the suppressive activity of myeloid-derived suppressor cells be "chop"ped?

scientific article published on 01 September 2014

Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors

scientific article published in November 2017

Cellular immunotherapy for soft tissue sarcomas.

scientific article published on March 2012

Changes in Aged Fibroblast Lipid Metabolism Induce Age-dependent Melanoma Cell Resistance to Targeted Therapy Via the Fatty Acid Transporter FATP2

scientific article published on 04 June 2020

Changes in Dendritic Cell Phenotype After a New High-dose Weekly Schedule of Interleukin-2 Therapy for Kidney Cancer and Melanoma ⬇️

scientific article published on October 1, 2010

Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice

scientific article published on 27 September 2011

Chemotherapy enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice

scientific article

Classification of current anticancer immunotherapies

scientific article

Combination of chemotherapy and immunotherapy for cancer: a paradigm revisited

scientific article published on 01 January 2007

Combination of external beam radiotherapy (EBRT) with intratumoral injection of dendritic cells as neo-adjuvant treatment of high-risk soft tissue sarcoma patients

scientific article

Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer

scientific article published on 01 February 2006

Combined inhibition of Notch signaling and Bcl-2/Bcl-xL results in synergistic antimyeloma effect

scientific article

Combined modality immunotherapy and chemotherapy: a new perspective

scientific article published on 17 May 2008

Comment on "Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells"

scientific article published on 01 April 2007

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

scientific article published on 25 February 2015

Coordinated regulation of myeloid cells by tumours

scientific article

Correlative studies of a Phase II clinical study of bavituximab and sorafenib in patients with advanced hepatocellular carcinoma

scientific article

Dendritic Vaccines--Fifth International Meeting. Dendritic cell vaccination and other strategies to tip the balance of the immune system. 16-18 July 2007, Bamberg, Germany

scientific article published on 01 October 2007

Dendritic cell vaccines for cancer treatment.

scientific article

Dendritic cell-based full-length survivin vaccine in treatment of experimental tumors

scientific article published on 01 February 2007

Dendritic cells and tumor microenvironment: a dangerous liaison

scientific article published on January 2006

Dendritic cells in cancer: the role revisited

scientific article published on 10 February 2017

Dendritic cells transfected with adenoviral vectors as vaccines

scientific article published on January 2014

Detecting Prostate Cancer Using Pattern Recognition Neural Networks With Flow Cytometry-Based Immunophenotyping in At-Risk Men

scientific article published on 17 April 2020

Developing dendritic cells become 'lacy' cells packed with fat and glycogen

scientific article

Development of vaccines against self-antigens: the p53 paradigm.

scientific article

Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer

scientific article published on 01 December 2020

Dynamic change and impact of myeloid-derived suppressor cells in allogeneic bone marrow transplantation in mice

scientific article

ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis

scientific article

Editorial overview: Many shades of grey: how immune response is regulated by tumors.

scientific article

Editorial: The intricacy of choice: can bacteria decide what type of myeloid cells to stimulate?

scientific article published on November 2014

Effect of tumor-derived cytokines and growth factors on differentiation and immune suppressive features of myeloid cells in cancer

scientific article published on September 2006

Effective combination of chemotherapy and dendritic cell administration for the treatment of advanced-stage experimental breast cancer

scientific article published on 01 January 2003

Effects of notch signaling on regulation of myeloid cell differentiation in cancer

scientific article

Entinostat Neutralizes Myeloid-Derived Suppressor Cells and Enhances the Antitumor Effect of PD-1 Inhibition in Murine Models of Lung and Renal Cell Carcinoma.

scientific article published on 11 July 2017

Entinostat plus pembrolizumab in patients with metastatic NSCLC previously treated with anti-PD-(L)1 therapy

scientific article published on 17 November 2020

Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer.

scientific article published on 27 January 2013

Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer.

scientific article published on 9 March 2018

Fatal attraction: How macrophages participate in tumor metastases

scientific article

Fatty acid transport protein 2 reprograms neutrophils in cancer

scientific article published on 17 April 2019

Full-length dominant-negative survivin for cancer immunotherapy.

scientific article published on December 2003

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells.

scientific article

H1(0) histone and differentiation of dendritic cells. A molecular target for tumor-derived factors.

scientific article

HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

scientific article published on 16 July 2019

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment ⬇️

scientific article published on September 27, 2010

Highlights of 10 years of immunology in Nature Reviews Immunology

scientific article published on 23 September 2011

Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function

scientific article

History of myeloid-derived suppressor cells

scientific article published in October 2013

Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer.

scientific article published on January 2004

Hypoxia-inducible factors in regulation of immune responses in tumour microenvironment

scientific article published on December 2014

ICAM-1 Deficiency in the Bone Marrow Niche Impairs Quiescence and Repopulation of Hematopoietic Stem Cells

ICAM-1 controls development and function of ILC2

article

INGN 201 (Advexin): adenoviral p53 gene therapy for cancer

scientific article published on August 2006

INGN-225: a dendritic cell-based p53 vaccine (Ad.p53-DC) in small cell lung cancer: observed association between immune response and enhanced chemotherapy effect

scientific article

Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs

scientific article published on 25 June 2019

Immature myeloid cells and cancer-associated immune suppression

scientific article

Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells

scientific article

Immune tolerance in breast cancer

scientific article

Immunologic monitoring of cancer vaccine therapy: results of a workshop sponsored by the Society for Biological Therapy.

scientific article

Induction of myelodysplasia by myeloid-derived suppressor cells.

scientific article

Influence of Targeted Therapy in Redefining High-Risk Myeloma. ⬇️

scholarly article

Inhibition of Casein Kinase 2 Disrupts Differentiation of Myeloid Cells in Cancer and Enhances the Efficacy of Immunotherapy in Mice

Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy

scientific article published on 26 November 2007

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

scientific article

Inhibition of myeloid cell differentiation in cancer: the role of reactive oxygen species

scientific article published on 01 August 2003

Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell lines

scientific article published on 11 December 2003

Isolation and Phenotyping of Splenic Myeloid-Derived Suppressor Cells in Murine Cancer Models

scientific article published on 01 January 2021

Kinase inhibitor Sorafenib modulates immunosuppressive cell populations in a murine liver cancer model.

scientific article published on 14 February 2011

Lactoferrin-induced myeloid-derived suppressor cell therapy attenuates pathologic inflammatory conditions in newborn mice

scientific article published on 01 October 2019

Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients.

scientific article

Lipid accumulation and dendritic cell dysfunction in cancer

journal article published in 2010

Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer

scientific article

Loss of Rb1 by epigenetic modification regulates expansion of MDSC in cancer

MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer

scientific article published on 03 October 2019

Mass-spectrometric characterization of peroxidized and hydrolyzed lipids in plasma and dendritic cells of tumor-bearing animals

journal article published in 2011

Mechanism and therapeutic reversal of immune suppression in cancer

scientific article

Mechanism of T cell tolerance induced by myeloid-derived suppressor cells.

scientific article

Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells

scientific article

Mechanism of synergistic effect of chemotherapy and immunotherapy of cancer ⬇️

scientific article published on October 26, 2010

Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells

scientific article

Mechanisms and clinical prospects of Notch inhibitors in the therapy of hematological malignancies

scientific article published on 31 October 2008

Mechanisms and functional significance of tumour-induced dendritic-cell defects

scientific article

Microenvironment Induced Myelodysplastic Syndrome (MDS) in S100A9 Transgenic Mice Caused by Myeloid-Derived Suppressor Cells (MDSC) ⬇️

scholarly article

Molecular mechanisms and therapeutic reversal of immune suppression in cancer

scientific article published on 01 February 2007

Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function ⬇️

scientific article published on November 8, 2010

Molecular pathways: tumor-infiltrating myeloid cells and reactive oxygen species in regulation of tumor microenvironment

scientific article

Molecular speciation and dynamics of oxidized triacylglycerols in lipid droplets: mass spectrometry and coarse-grained simulations

journal article published in 2014

MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis

scientific article

Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis

scientific article published on 27 June 2019

Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth

scientific article published on 16 May 2019

Myeloid-Derived Suppressor Cells

scientific article published on January 2017

Myeloid-Derived Suppressor Cells in Human Cancer ⬇️

scientific article published on July 1, 2010

Myeloid-derived suppressor cells

scientific article published on January 2007

Myeloid-derived suppressor cells are a major source of Wnt5A in the melanoma microenvironment and depend on Wnt5A for full suppressive activity

scientific article published on 01 December 2020

Myeloid-derived suppressor cells as regulators of the immune system

scientific article (publication date: March 2009)

Myeloid-derived suppressor cells coming of age.

scientific article

Myeloid-derived suppressor cells in the development of lung cancer

scientific article

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

scientific article

Myeloid-derived suppressor cells regulate growth of multiple myeloma by inhibiting T cells in bone marrow.

scientific article published on 4 March 2013

Neutrophils and PMN-MDSC: Their biological role and interaction with stromal cells

scientific article published on 15 December 2017

New roles of Rb1 in expansion of MDSCs in cancer

scientific article published on 11 April 2013

Notch and wingless signaling cooperate in regulation of dendritic cell differentiation

scientific article published on 11 June 2009

Notch signaling in differentiation and function of dendritic cells

scientific article published on January 2008

Notch signaling is necessary but not sufficient for differentiation of dendritic cells.

scientific article published on 7 August 2003

Novel mechanism of synergistic effects of conventional chemotherapy and immune therapy of cancer

scientific article published on 20 February 2013

Oxidized lipids block antigen cross-presentation by dendritic cells in cancer

scientific article

PPT1 Inhibition enhances the anti-tumor activity of anti-PD-1 antibody in melanoma

scientific article published on 11 August 2020

Pathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blockade in metastatic melanoma

scientific article published on 15 October 2021

Phenotypic and functional analysis of dendritic cells and clinical outcome in patients with high-risk melanoma treated with adjuvant granulocyte macrophage colony-stimulating factor

scientific article published on 01 July 2008

Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization.

scientific article

Plasticity of myeloid-derived suppressor cells in cancer

scientific article published on 14 March 2018

Polymorphonuclear myeloid-derived suppressor cells limit antigen cross-presentation by dendritic cells in cancer

scientific article published on 25 June 2020

ROR1C Regulates Differentiation of Myeloid-Derived Suppressor Cells

scientific article

Radiation-induced autophagy potentiates immunotherapy of cancer via up-regulation of mannose 6-phosphate receptor on tumor cells in mice

scientific article

Randomized-controlled phase II trial of salvage chemotherapy after immunization with a TP53-transfected dendritic cell-based vaccine (Ad.p53-DC) in patients with recurrent small cell lung cancer

scientific article published on 27 December 2018

Rational design of shepherdin, a novel anticancer agent.

scientific article

Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils

scientific article published on 01 December 2020

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

scientific article

Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death

scientific article published on 17 February 2020

Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway

scientific article

Regulation of dendritic cell differentiation and function by Notch and Wnt pathways

scientific article published on March 2010

Regulation of dendritic cell differentiation in bone marrow during emergency myelopoiesis

scientific article published on 05 July 2013

Regulation of dendritic-cell differentiation by bone marrow stroma via different Notch ligands

scientific article published on 14 September 2006

Regulation of plasmacytoid dendritic cell development in mice by aryl hydrocarbon receptor

scientific article published on 29 October 2013

Regulation of suppressive function of myeloid-derived suppressor cells by CD4+ T cells

scientific article published on 31 January 2012

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

scientific article published on 21 December 2003

Regulation of tumor metastasis by myeloid-derived suppressor cells

scientific article

Regulatory myeloid suppressor cells in health and disease

scientific article published on 14 September 2009

Role of immature myeloid cells in mechanisms of immune evasion in cancer

scientific article

STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion

scientific article published on 01 April 2005

Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors

scientific article published on 29 August 2017

Secretory IgM Exacerbates Tumor Progression by Inducing Accumulations of MDSCs in Mice

scientific article published on 12 April 2018

Selective Targeting of Myeloid-Derived Suppressor Cells in Cancer Patients Using DS-8273a, an Agonistic TRAIL-R2 Antibody.

scientific article published on 13 December 2016

Selective targeting of different populations of myeloid-derived suppressor cells by histone deacetylase inhibitors

scientific article published on 20 May 2020

Serial assessment of lymphocytes and apoptosis in the prostate during coordinated intraprostatic dendritic cell injection and radiotherapy

scientific article published on April 2012

Survivin-specific CD4+ T cells are decreased in patients with survivin-positive myeloma

scientific article published on 19 May 2015

Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements

scientific article published on 13 June 2018

Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer

scientific article published on 11 September 2017

Targeting of Jak/STAT pathway in antigen presenting cells in cancer

scientific article published on February 2007

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

scientific article

The Ratio of Peripheral Regulatory T Cells to Lox-1 PMN-MDSC Predicts the Early Response to Anti-PD-1 Therapy in Non-Small Cell Lung Cancer Patients

scientific article published on 01 January 2019

The biology of myeloid‐derived suppressor cells: The blessing and the curse of morphological and functional heterogeneity ⬇️

scientific article published on November 1, 2010

The role of mannose-6-phosphate receptor and autophagy in influencing the outcome of combination therapy

scientific article published on 16 January 2013

The terminology issue for myeloid-derived suppressor cells

scientific article published on January 2007

Therapeutic effect of intratumoral administration of DCs with conditional expression of combination of different cytokines

scientific article published on 6 January 2012

Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer

scientific article published on 16 April 2013

Therapies for tuberculosis and AIDS: myeloid-derived suppressor cells in focus

scientific article published on 18 May 2020

Transcriptional factor ATF3 protects against colitis by regulating follicular helper T cells in Peyer's patches

scientific article published on 12 March 2019

Transcriptional regulation of myeloid-derived suppressor cells

scientific article

Transitory presence of myeloid-derived suppressor cells in neonates is critical for control of inflammation.

scientific article published on 15 January 2018

Tumor Escape from Immune Response: Mechanisms and Targets of Activity ⬇️

scientific article published on October 1, 2003

Tumor escape mechanism governed by myeloid-derived suppressor cells

scientific article published on April 2008

Tumor-associated CD8+ T cell tolerance induced by bone marrow-derived immature myeloid cells

scientific article

Tumor-induced STAT3 signaling in myeloid cells impairs dendritic cell generation by decreasing PKCβII abundance

scientific article

Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice

scientific article

Understanding the tumor immune microenvironment (TIME) for effective therapy.

scientific article published on 23 April 2018

Unique pattern of neutrophil migration and function during tumor progression

article

Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer

scientific article published on 18 August 2021

VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression

scientific article published on 13 February 2003

Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses

scientific article published on 01 August 2007

ΔNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer

scientific article published on 08 October 2018

β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation

scientific article published on 11 July 2016

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