Search filters

List of works by Michael Cowley

A BAT-Centric Approach to the Treatment of Diabetes: Turn on the Brain

scientific article

A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding

scientific article published in August 2017

A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding

scientific article published in September 2017

A Pre-Hospital Patient Education Program Improves Outcomes of Bariatric Surgery

scientific article published on 6 February 2016

Abdominal fat analyzed by DEXA scan reflects visceral body fat and improves the phenotype description and the assessment of metabolic risk in mice

scientific article published on 03 July 2012

Activation of central melanocortin pathways by fenfluramine

scientific article

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice

scientific article

Appropriate inhibition of orexigenic hypothalamic arcuate nucleus neurons independently of leptin receptor/STAT3 signaling.

scientific article published in January 2007

Brain Feeding Circuits after Roux-en-Y Gastric Bypass

scientific article published on 20 February 2018

Catecholamine reuptake inhibition causes weight loss by increasing locomotor activity and thermogenesis

scientific article published on 8 August 2007

Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus

scientific article published on 07 December 2018

Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1

scientific article published on 28 August 2018

Central serotonin and melanocortin pathways regulating energy homeostasis

scientific article

Changes of peripheral alpha-melanocyte-stimulating hormone in childhood obesity

scientific article

Characterization of brainstem peptide YY (PYY) neurons

scientific article

Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques

scientific article

Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease

scientific article

Comparison of combined bupropion and naltrexone therapy for obesity with monotherapy and placebo

scientific article published on 21 October 2009

Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes

scientific article published in Nature Communications

Current and emerging pharmacotherapies for obesity in Australia

scientific article

Deficient melanocortin-4 receptor causes abnormal reproductive neuroendocrine profile in female mice

scientific article published in March 2017

Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice

scientific article published on 18 July 2017

Determining the Effects of Combined Liraglutide and Phentermine on Metabolic Parameters, Blood Pressure, and Heart Rate in Lean and Obese Male Mice

scientific article published on 23 January 2019

Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pup

scientific article

Developmental switch in neuropeptide Y and melanocortin effects in the paraventricular nucleus of the hypothalamus

scientific article

Developmental switch of leptin signaling in arcuate nucleus neurons

scientific article

Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons

scientific article published on 8 September 2010

Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons

scientific article

Dietary Macronutrient Composition Directs ChREBP Isoform Expression and Glucose Metabolism in Mice.

scientific article

Does leptin cause an increase in blood pressure in animals and humans?

scientific article published on 27 October 2016

Early overnutrition results in early-onset arcuate leptin resistance and increased sensitivity to high-fat diet

scientific article

Effects of Bariatric Surgery on Liver Function Tests in Patients with Nonalcoholic Fatty Liver Disease

scientific article

Effects of nutritional manipulation on body composition in the developing marsupial, Macropus eugenii

scientific article published on 28 March 2016

Electrophysiological actions of peripheral hormones on melanocortin neurons

scientific article

Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance

scientific article published on 13 October 2011

Estradiol prevents fat accumulation and overcomes leptin resistance in female high-fat diet mice

scientific article published on 22 August 2014

Estrogen transiently increases delayed rectifier, voltage-dependent potassium currents in ovine gonadotropes.

scientific article published in April 1999

Excess of nerve growth factor in the ovary causes a polycystic ovary-like syndrome in mice, which closely resembles both reproductive and metabolic aspects of the human syndrome

scientific article

Excess weight gain during the early postnatal period is associated with permanent reprogramming of brown adipose tissue adaptive thermogenesis

scientific article published on 24 May 2007

Feeding induced by cannabinoids is mediated independently of the melanocortin system

scientific article

GLP-1 analogs: satiety without malaise?

scientific article published on 27 June 2007

Ghrelin--satisfying a hunger for the mechanism

scientific article

Ghrelin.

scientific article

Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity

scientific article published on 29 August 2007

Gut hormone PYY(3-36) physiologically inhibits food intake

scientific article

Hyperphagia in male melanocortin 4 receptor deficient mice promotes growth independently of growth hormone

scientific article published on 25 August 2016

Hypertension in obesity: is leptin the culprit? ⬇️

scientific article published on January 17, 2013

Hypothalamic Insulin Resistance in Obesity: Effects on Glucose Homeostasis

scientific article published on 26 January 2017

Hypothalamic POMC neurons promote cannabinoid-induced feeding

scientific article published on 18 February 2015

Hypothalamic circuitry of neuropeptide Y regulation of neuroendocrine function and food intake via the Y5 receptor subtype

scientific article published on 01 August 2001

Hypothalamic melanocortin neurons integrate signals of energy state ⬇️

scientific article published on November 7, 2003

Hypothalamic regulatory pathways and potential obesity treatment targets

scientific article

Inhibition of dopamine and norepinephrine reuptake produces additive effects on energy balance in lean and obese mice

scientific article

Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production

scientific article

Insulin regulates POMC neuronal plasticity to control glucose metabolism

article by Garron T. Dodd et al published 19 September 2018 in eLife

Is ghrelin a signal for the development of metabolic systems?

scientific article

Leptin Effects on DAT Neurons To Control Energy Homeostasis

scientific article published in December 2017

Leptin Signaling in the Arcuate Nucleus Reduces Insulin's Capacity to Suppress Hepatic Glucose Production in Obese Mice

scientific article published on 01 January 2019

Leptin action in the dorsomedial hypothalamus increases sympathetic tone to brown adipose tissue in spite of systemic leptin resistance

scientific article published on August 2011

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

scientific article (publication date: 24 May 2001)

Leptin and insulin act on POMC neurons to promote the browning of white fat.

scientific article published on January 2015

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis

scientific article published in January 2006

Leptin increasing sympathetic nerve outflow in obesity: A cure for obesity or a potential contributor to metabolic syndrome?

scientific article published on July 2012

Leptin mediates the increase in blood pressure associated with obesity

scientific article

Leptin reduces food intake via a dopamine D2 receptor-dependent mechanism

scientific article published on 27 July 2012

Leptin resistance and obesity

scientific article

Leptin stimulates neuropeptide Y and cocaine amphetamine-regulated transcript coexpressing neuronal activity in the dorsomedial hypothalamus in diet-induced obese mice

scientific article published on September 2013

Mechanisms of leptin action and leptin resistance

scientific article

Mitochondrial uncoupling in the melanocortin system differentially regulates NPY and POMC neurons to promote weight-loss

scientific article published on 8 July 2017

Modified thresholds for fibrosis risk scores in nonalcoholic fatty liver disease are necessary in the obese

scientific article

Naltrexone/bupropion for obesity: an investigational combination pharmacotherapy for weight loss

scientific article published on 19 April 2014

Neuropeptide Y Y5 receptor protein in the cortical/limbic system and brainstem of the rat: expression on gamma-aminobutyric acid and corticotropin-releasing hormone neurons

scientific article published on 01 January 2000

New insights in leptin resistance mechanisms in mice

scientific article published on 24 September 2015

Pancreatic polypeptide in obese children before and after weight loss.

scientific article

Paradoxical effect of gonadotrophin-inhibiting hormone to negatively regulate neuropeptide Y neurones in mouse arcuate nucleus.

scientific article published in December 2013

Peptide YY is a regulator of energy homeostasis in obese children before and after weight loss

scientific article published on 4 October 2005

Peptide YY(3-36) inhibits morning, but not evening, food intake and decreases body weight in rhesus macaques

scientific article

Physiological evidence for the involvement of peptide YY in the regulation of energy homeostasis in humans

scientific article published in September 2006

Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons.

scientific article published on August 2017

Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.

scientific article

Prevention of the adverse effects of olanzapine on lipid metabolism with the antiepileptic zonisamide

scientific article published on 8 April 2017

Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes

scientific article published in Nature Communications

Rational design of a combination medication for the treatment of obesity

scientific article

Regulation of agouti-related protein messenger ribonucleic acid transcription and peptide secretion by acute and chronic inflammation

scientific article

Regulation of central melanocortin signaling by interleukin-1 beta

scientific article

Regulatory links between imprinted genes: evolutionary predictions and consequences

scientific article

Repeated weight cycling in obese mice causes increased appetite and glucose intolerance

scientific article published on 26 May 2018

Serotonergic pathways converge upon central melanocortin systems to regulate energy balance

scientific article

Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake

scientific article published on 01 July 2006

Sex differences in the metabolic effects of testosterone in sheep

scientific article published on 29 November 2011

Short-term high-fat diet increases the presence of astrocytes in the hypothalamus of C57BL6 mice without altering leptin sensitivity.

scientific article

Speed-dieting: dopamine agonists promote weight loss

scientific article published on 01 September 2019

Starvation after AgRP neuron ablation is independent of melanocortin signaling

scholarly article

Suppression of basal spontaneous gonadotropin-releasing hormone neuronal activity during lactation: role of inhibitory effects of neuropeptide Y.

scientific article published on 21 August 2008

Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity.

scientific article

The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis

scientific article published on 01 December 2001

The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss

scientific article

The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis

scientific article published in February 2003

The electrophysiology of feeding circuits

scientific article

The role of thermogenesis in antipsychotic drug-induced weight gain.

scientific article

To be or NUCB2, is nesfatin the answer?

scientific article published on December 2006

Transmitter Time: Synaptic Plasticity and Metabolic Memory in the Hypothalamus ⬇️

scientific article published on February 16, 2012

Using intranasal lidocaine to reduce food intake

scientific article published on 28 November 2006

Weight loss after laparoscopic adjustable gastric band and resolution of the metabolic syndrome and its components.

scientific article published on 6 March 2017

Zonisamide prevents olanzapine-associated hyperphagia, weight gain, and elevated blood glucose in rats

scientific article

α-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPK

scientific article (publication date: 2016)

α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors

scientific article published on 05 August 2016

Paulina is supported by:

About Paulina

Help