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List of works by Wojciech Kamysz

A Highly Selective Biosensor Based on Peptide Directly Derived from the HarmOBP7 Aldehyde Binding Site

scientific article published on 03 October 2019

A novel mechanism of action of the fumagillin analog, TNP-470, in the B16F10 murine melanoma cell line.

scientific article published on September 2005

Activities of synthetic peptides against human pathogenic bacteria

scientific article published on 01 January 2004

Activity of Antimicrobial Peptides and Conventional Antibiotics against Superantigen Positive Staphylococcus aureus Isolated from the Patients with Neoplastic and Inflammatory Erythrodermia

scientific article published on 12 May 2011

Activity of Temporin A and Short Lipopeptides Combined with Gentamicin against Biofilm Formed by Staphylococcus aureus and Pseudomonas aeruginosa

scientific article published on 02 September 2020

Activity of antimicrobial peptides and conventional antibiotics against superantigen positive Staphylococcus aureus isolated from patients with atopic dermatitis.

scientific article

Activity of antimicrobial peptides, alone or combined with conventional antibiotics, against Staphylococcus aureus isolated from the airways of cystic fibrosis patients.

scientific article published on 22 July 2016

Activity of diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside, its hydrochloride, and N,N-dialkyl derivatives against non-albicans Candida isolates.

scientific article published on 26 February 2018

Activity of short lipopeptides and conventional antimicrobials against planktonic cells and biofilms formed by clinical strains of Staphylococcus aureus.

scientific article published on August 2012

Administration of protegrin peptide IB-367 to prevent endotoxin induced mortality in bile duct ligated rats

scientific article published on June 2003

Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2.

scientific article published on 01 September 2019

Amphibian peptides prevent endotoxemia and bacterial translocation in bile duct-ligated rats

scientific article

Anti-inflammatory and antibacterial effects of human cathelicidin active fragment KR-12 in the mouse models of colitis: a novel potential therapy of inflammatory bowel diseases

scientific article published on 21 November 2020

Antibacterial Activities of Lipopeptide (C)₂-KKKK-NH₂ Applied Alone and in Combination with Lens Liquids to Fight Biofilms Formed on Polystyrene Surfaces and Contact Lenses

scientific article published on 17 January 2019

Antibacterial Activity of Synthetic Peptides Against Plant Pathogenic Pectobacterium Species

article

Anticancer effects of CAMEL peptide

scientific article published on 8 March 2010

Antiendotoxin activity of protegrin analog IB-367 alone or in combination with piperacillin in different animal models of septic shock

scientific article published in November 2003

Antimicrobial Activity of Selected Antimicrobial Peptides Against Planktonic Culture and Biofilm of Acinetobacter baumannii

scientific article published on 01 March 2019

Antimicrobial activity of alcohols from Musca domestica

scientific article published on 12 June 2012

Antimicrobial activity of different antimicrobial peptides (AMPs) against clinical methicillin-resistant Staphylococcus aureus (MRSA)

scientific article published on 01 January 2018

Antimicrobial activity of untypical lipid compounds in the cuticular and internal lipids of four fly species.

scientific article published on 18 November 2013

Antimicrobial and conformational studies of the active and inactive analogues of the protegrin-1 peptide.

scientific article published on 13 January 2010

Antimicrobial peptide-induced apoptotic death of leishmania results from calcium-de pend ent, caspase-independent mitochondrial toxicity

scientific article published on 8 April 2009

Antimicrobial peptides (Temporin A and Iseganan IB-367): effect on the cysticerci of Taenia crassiceps.

scientific article published on 25 December 2008

Antimicrobial peptides as potential tool to fight bacterial biofilm

scientific article published on January 2014

Antimicrobial preservative effectiveness of natural peptide antibiotics

scientific article published in September 2005

Antitumor activity of antimicrobial peptides against U937 histiocytic cell line

scientific article published on March 14, 2011

Antitumor activity of opiorphin, sialorphin and their conjugates with a peptide klaklakklaklak

scientific article published on 9 November 2016

Application of HS-SPME-GC-MS for the analysis of aldehydes produced by different insect species and their antifungal activity

scientific article published on 07 January 2020

Are antimicrobial peptides an alternative for conventional antibiotics?

scientific article published in January 2005

Binding of Ni2+ and Cu2+ ions to peptides with a Cys-His motif

scientific article

Bioelectronic nose: Current status and perspectives.

scientific article

Bioelectronic tongue: Current status and perspectives

scientific article published on 26 November 2019

Biological and surface-active properties of double-chain cationic amino acid-based surfactants

scientific article published on 19 April 2014

Capping Agent-Dependent Toxicity and Antimicrobial Activity of Silver Nanoparticles: An In Vitro Study. Concerns about Potential Application in Dental Practice.

scientific article

Cationic Net Charge and Counter Ion Type as Antimicrobial Activity Determinant Factors of Short Lipopeptides

scientific article published on February 2017

Characterization of the effects of opiorphin and sialorphin and their analogs substituted in position 1 with pyroglutamic acid on motility in the mouse ileum

scientific article published on 4 February 2013

Citropin 1.1 Trifluoroacetate to Chloride Counter-Ion Exchange in HCl-Saturated Organic Solutions: An Alternative Approach.

scientific article

Citropin 1.1-treated central venous catheters improve the efficacy of hydrophobic antibiotics in the treatment of experimental staphylococcal catheter-related infection

scientific article

Co-immobilization of Palm and DNase I for the development of an effective anti-infective coating for catheter surfaces.

scientific article published on 8 August 2016

Colorimetric evaluation of the time-killing assay for Citropin 1.1, lipopeptide Palm-KK-NH2, and Temporin A.

scientific article published in May 2011

Comparative Study on Antistaphylococcal Activity of Lipopeptides in Various Culture Media.

scientific article

Comparative activities of cecropin A, melittin, and cecropin A-melittin peptide CA(1-7)M(2-9)NH2 against multidrug-resistant nosocomial isolates of Acinetobacter baumannii.

scientific article

Comparing selection on S. aureus between antimicrobial peptides and common antibiotics

scientific article (publication date: 2013)

Competition between histamine-like and poly-imidazole coordination sites for Cu(2+) and Zn(2+) ions in zebra-fish peptide of prion-like protein.

scientific article published on 16 August 2010

Complexes between some lysine-containing peptides and crown ethers--electrospray ionization mass spectrometric study.

scientific article

Composition and antimicrobial activity of fatty acids detected in the hygroscopic secretion collected from the secretory setae of larvae of the biting midge Forcipomyia nigra (Diptera: Ceratopogonidae).

scientific article published on 7 July 2012

Conformational solution studies of the anti-microbial temporin A retro-analogues by using NMR spectroscopy.

scientific article published in May 2007

Coordination of Ni2+ and Cu2+ to metal ion binding domains of E. coli SlyD protein.

scientific article

Copper binding to chicken and human prion protein amylodogenic regions: differences and similarities revealed by Ni2+ as a diamagnetic probe

scientific article published on 14 October 2009

Counter-ion effect on antistaphylococcal activity and cytotoxicity of selected antimicrobial peptides

scientific article published on 6 January 2018

Critical review of electronic nose and tongue instruments prospects in pharmaceutical analysis

scientific article published on 15 May 2019

Cu2+ and Ni2+ interactions with N-terminal fragments of Hpn and Hpn-like proteins from Helicobacter pylori

scientific article published on 13 November 2010

CuII binding sites located at His-96 and His-111 of the human prion protein: thermodynamic and spectroscopic studies on model peptides

scientific article published on 13 August 2008

Decolonization of Staphylococcus aureus in patients with atopic dermatitis: a reason for increasing resistance to antibiotics?

scientific article published on 31 December 2017

Design of protease-resistant pexiganan enhances antileishmanial activity

scientific article published in May 2014

Design, synthesis and biological evaluation of betulin-3-yl 2-amino-2-deoxy-β-d-glycopyranosides

scientific article published on 11 January 2020

Determination of counter-ions in synthetic peptides by ion chromatography, capillary isotachophoresis and capillary electrophoresis

scientific article published on 17 January 2012

Diosgenyl 2-amino-2-deoxy-β-D-galactopyranoside: synthesis, derivatives and antimicrobial activity

scientific article published in November 2017

Double-Headed Cationic Lipopeptides: An Emerging Class of Antimicrobials

scientific article published on 25 November 2020

Effect of Disulfide Cyclization of Ultrashort Cationic Lipopeptides on Antimicrobial Activity and Cytotoxicity

scientific article published on 29 September 2020

Effect of cryogrinding on chemical stability of the sparingly water-soluble drug furosemide

scientific article

Effect of omiganan on colonic anastomosis healing in a rat model of peritonitis

scientific article published on 15 July 2017

Effect of self-assembly on antimicrobial activity of double-chain short cationic lipopeptides

scientific article published on 17 October 2019

Effects of pexiganan alone and combined with betalactams in experimental endotoxic shock.

scientific article published on February 2005

Efficacy of Pexiganan Combination with Tigecycline in a Mouse Model of Pseudomonas aeruginosa Sepsis

scientific article published on 01 January 2018

Efficacy of tachyplesin III, colistin, and imipenem against a multiresistant Pseudomonas aeruginosa strain

scientific article published on 2 April 2007

Efficacy of the combination of tachyplesin III and clarithromycin in rat models of Escherichia coli sepsis

scientific article published on 8 September 2008

Evaluation of Three Peptide Immobilization Techniques on a QCM Surface Related to Acetaldehyde Responses in the Gas Phase

article

Evidence for potential functionality of nuclearly-encoded humanin isoforms.

scientific article

Free fatty acids in the cuticular and internal lipids of Calliphora vomitoria and their antimicrobial activity

scientific article published on 16 February 2013

Genome-wide mRNA profiling identifies RCAN1 and GADD45A as regulators of the transitional switch from survival to apoptosis during ER stress

scientific article published on 27 December 2019

Homocysteine is a novel risk factor for suboptimal response of blood platelets to acetylsalicylic acid in coronary artery disease: a randomized multicenter study

scientific article

Human host defense peptides - role in maintaining human homeostasis and pathological processes

scientific article published on 12 December 2016

Hydrocarbon Stapled Antimicrobial Peptides.

scientific article published on 12 January 2018

IB-367 pre-treatment improves the in vivo efficacy of teicoplanin and daptomycin in an animal model of wounds infected with meticillin-resistant Staphylococcus aureus

scientific article published on 27 June 2013

Identification and antifungal activity of novel organic compounds found in cuticular and internal lipids of medically important flies.

scientific article published on 26 June 2014

In Vitro Efficiency of Antimicrobial Peptides against Staphylococcal Pathogens Associated with Canine Pyoderma

scientific article published on 11 March 2020

In Vitro Evaluation of Cytotoxicity and Permeation Study on Lysine- and Arginine-Based Lipopeptides with Proven Antimicrobial Activity.

scientific article published on 8 December 2017

In Vitro Evaluation of the Allergic Potential of Antibacterial Peptides: Camel and Citropin

scientific article published on 14 December 2015

In vitro activities of tachyplesin III against Pseudomonas aeruginosa

scientific article published on 13 January 2007

In vitro activities of the lipopeptides palmitoyl (Pal)-Lys-Lys-NH(2) and Pal-Lys-Lys alone and in combination with antimicrobial agents against multiresistant gram-positive cocci

scientific article published on 23 October 2006

In vitro activity and in vivo animal model efficacy of IB-367 alone and in combination with imipenem and colistin against Gram-negative bacteria

scientific article published on 14 February 2014

In vitro activity and in vivo efficacy of the saponin diosgenyl 2-amino-2-deoxy- -D-glucopyranoside hydrochloride (HSM1) alone and in combination with daptomycin and vancomycin against Gram-positive cocci

scientific article published on 21 April 2011

In vitro activity and killing effect of citropin 1.1 against gram-positive pathogens causing skin and soft tissue infections

scientific article

In vitro activity and killing effect of temporin A on nosocomial isolates of Enterococcus faecalis and interactions with clinically used antibiotics.

scientific article published on 13 January 2005

In vitro activity and killing effect of the synthetic hybrid cecropin A-melittin peptide CA(1-7)M(2-9)NH(2) on methicillin-resistant nosocomial isolates of Staphylococcus aureus and interactions with clinically used antibiotics

scientific article published in July 2004

In vitro activity and killing effect of uperin 3.6 against gram-positive cocci isolated from immunocompromised patients.

scientific article published on September 2005

In vitro activity of MSI-78 alone and in combination with antibiotics against bacteria responsible for bloodstream infections in neutropenic patients

scientific article published in September 2005

In vitro activity of Protegrin-1, alone and in combination with clinically useful antibiotics, against Acinetobacter baumannii strains isolated from surgical wounds

scientific article published on 18 June 2019

In vitro activity of amphibian peptides alone and in combination with antimicrobial agents against multidrug-resistant pathogens isolated from surgical wound infection

scientific article published on 22 April 2005

In vitro activity of aurein 1.2 alone and in combination with antibiotics against gram-positive nosocomial cocci.

scientific article published on 12 January 2007

In vitro activity of citropin 1.1 alone and in combination with clinically used antimicrobial agents against Rhodococcus equi

scientific article published on 27 June 2005

In vitro activity of synthetic antimicrobial peptides against Candida

scientific article published on 01 January 2006

In vitro activity of the histatin derivative P-113 against multidrug-resistant pathogens responsible for pneumonia in immunocompromised patients

scientific article

In vitro activity of the protegrin IB-367 alone and in combination compared with conventional antifungal agents against dermatophytes

scientific article

In vitro activity of the synthetic lipopeptide PAL-Lys-Lys-NH(2) alone and in combination with antifungal agents against clinical isolates of Cryptococcus neoformans

scientific article published on 17 July 2007

In vitro and in vivo effects of sub-MICs of pexiganan and imipenem on Pseudomonas aeruginosa adhesion and biofilm development

scientific article published on December 2013

In vitro effect of short-term exposure to two synthetic peptides, alone or in combination with clarithromycin or rifabutin, on Cryptosporidium parvum infectivity

scientific article published in May 2002

In vitro susceptibility of dermatophytes to conventional and alternative antifungal agents

scientific article

In-vitro activity of the synthetic protegrin IB-367 alone and in combination with antifungal agents against clinical isolates of Candida spp.

scientific article published in October 2007

Inactivation of human kininogen-derived antimicrobial peptides by secreted aspartic proteases produced by the pathogenic yeast Candida albicans.

scientific article published on 16 July 2015

Increasing rate of daptomycin non-susceptible strains of Staphylococcus aureus in patients with atopic dermatitis.

scientific article published on 31 December 2017

Influence of Amphibian Antimicrobial Peptides and Short Lipopeptides on Bacterial Biofilms Formed on Contact Lenses.

scientific article

Influence of Dimerization of Lipopeptide Laur-Orn-Orn-Cys-NH2 and an N-terminal Peptide of Human Lactoferricin on Biological Activity

scientific article

Influence of Short Cationic Lipopeptides with Fatty Acids of Different Chain Lengths on Bacterial Biofilms Formed on Polystyrene and Hydrogel Surfaces

scientific article published on 01 October 2019

Kinin release from human kininogen by 10 aspartic proteases produced by pathogenic yeast Candida albicans

scientific article published on 4 March 2015

Lipidated Analogs of the LL-37-Derived Peptide Fragment KR12-Structural Analysis, Surface-Active Properties and Antimicrobial Activity

scientific article published on 30 January 2020

Lipopeptide Laur-CKK-NH2 dimer preserves daptomycin susceptibility and enhances its activity against Enterococcus faecalis

scientific article

Methods Used for the Eradication of Staphylococcal Biofilms

scientific article published on 04 October 2019

Molecular determinants of the interaction between human high molecular weight kininogen and Candida albicans cell wall: Identification of kininogen-binding proteins on fungal cell wall and mapping the cell wall-binding regions on kininogen molecule.

scientific article published on 28 October 2011

N-Alkyl derivatives of diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside; synthesis and antimicrobial activity.

scientific article

N-Aminoacyl and N-hydroxyacyl derivatives of diosgenyl 2-amino-2-deoxy-β-d-glucopyranoside: Synthesis, antimicrobial and hemolytic activities

scientific article published on 25 May 2019

Novel glycosylated endomorphin-2 analog produces potent centrally-mediated antinociception in mice after peripheral administration

scientific article published on 30 October 2013

Novel orally available salvinorin A analog PR-38 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome.

scientific article published on July 2014

Novel properties of antimicrobial peptides.

scientific article

Potential therapeutic role of cationic peptides in three experimental models of septic shock.

scientific article

Potential therapeutic role of histatin derivative P-113d in experimental rat models of Pseudomonas aeruginosa sepsis

scientific article

Pretreatment with the protegrin IB-367 affects Gram-positive biofilm and enhances the therapeutic efficacy of linezolid in animal models of central venous catheter infection

scientific article published in November 2007

Prophylactic efficacy of topical temporin A and RNAIII-inhibiting peptide in a subcutaneous rat Pouch model of graft infection attributable to staphylococci with intermediate resistance to glycopeptides

scientific article published on 28 July 2003

Protective effect of citropin 1.1 and tazobactam-piperacillin against oxidative damage and lethality in mice models of gram-negative sepsis

scientific article published on 20 April 2010

Rapid Screening of Antimicrobial Synthetic Peptides

scientific article published on 28 September 2015

Rapid screening of antibiotic toxicity in an automated microdroplet system

scientific article published on 16 March 2012

Release of biologically active kinin peptides, Met-Lys-bradykinin and Leu-Met-Lys-bradykinin from human kininogens by two major secreted aspartic proteases of Candida parapsilosis.

scientific article published on 13 August 2013

Retro analog concept: comparative study on physico-chemical and biological properties of selected antimicrobial peptides

scientific article published on 29 July 2017

Rose Bengal-Mediated Photoinactivation of Multidrug Resistant Is Enhanced in the Presence of Antimicrobial Peptides

scientific article published on 20 August 2018

Safety profile of antimicrobial peptides: camel, citropin, protegrin, temporin a and lipopeptide on HaCaT keratinocytes

scientific article published on September 2013

Searching for new strategies against biofilm infections: Colistin-AMP combinations against Pseudomonas aeruginosa and Staphylococcus aureus single- and double-species biofilms

scientific article

Secreted trypanosome cyclophilin inactivates lytic insect defense peptides and induces parasite calcineurin activation and infectivity

scientific article published on 5 February 2013

Self-assembly and interactions of short antimicrobial cationic lipopeptides with membrane lipids: ITC, FTIR and molecular dynamics studies

scientific article published on 28 June 2014

Shape-Depended Biological Properties of Ag3PO4 Microparticles: Evaluation of Antimicrobial Properties and Cytotoxicity in In Vitro Model-Safety Assessment of Potential Clinical Usage

scientific article published on 20 November 2019

Short arginine-rich lipopeptides: From self-assembly to antimicrobial activity

scientific article published on 07 September 2018

Silver Nanoparticles as Chlorhexidine and Metronidazole Drug Delivery Platforms: Their Potential Use in Treating Periodontitis

scientific article published on 02 February 2022

Sorption of ionic liquids onto soils: experimental and chemometric studies

scientific article published on 21 April 2012

Structural characterization and antimicrobial activity of the Zn(II) complex with P113 (demegen), a derivative of histatin 5.

scientific article

Structure activity relationship studies on the antimicrobial activity of novel edeine A and D analogues

scientific article published on 01 October 2006

Synergic combinations of antimicrobial peptides (AMPs) against biofilms of methicillin-resistant Staphylococcus aureus (MRSA) on polystyrene and medical devices

scientific article published on 30 October 2019

Synergistic effect of antimicrobial peptide LL-37 and colistin combination against multidrug-resistant <i>Escherichia coli</i> isolates

scientific article published in 2021

Synthesis and antimicrobial activity of truncated fragments and analogs of citropin 1.1: The solution structure of the SDS micelle-bound citropin-like peptides.

scientific article published on 16 July 2009

Synthesis, biological activity and solution structure of new analogues of the antimicrobial Gramicidin S.

scientific article published on 25 October 2010

Synthetic amphibian peptides and short amino-acids derivatives against planktonic cells and mature biofilm of Providencia stuartii clinical strains

scientific article published on January 2014

Tachyplesin III and granulocyte-colony stimulating factor enhance the efficacy of tazobactam/piperacillin in a neutropenic mouse model of polymicrobial peritonitis

scientific article published on 6 November 2007

Temporin A alone and in combination with imipenem reduces lethality in a mouse model of staphylococcal sepsis

scientific article published on 27 September 2005

Temporin A and its retro-analogues: synthesis, conformational analysis and antimicrobial activities

scientific article published in August 2006

Temporin A as a prophylactic agent against methicillin sodium-susceptible and methicillin sodium-resistant Staphylococcus epidermidis vascular graft infection.

scientific article published in November 2002

Temporin A is effective in MRSA-infected wounds through bactericidal activity and acceleration of wound repair in a murine model

scientific article published on 3 January 2008

Temporin A soaking in combination with intraperitoneal linezolid prevents vascular graft infection in a subcutaneous rat pouch model of infection with Staphylococcus epidermidis with intermediate resistance to glycopeptides

scientific article published on August 2004

The Analysis of Cu(II)/Zn(II) Cyclopeptide System as Potential Cu,ZnSOD Mimic Center.

scientific article published on 16 February 2017

The Antistaphylococcal Activity of Citropin 1.1 and Temporin A against Planktonic Cells and Biofilms Formed by Isolates from Patients with Atopic Dermatitis: An Assessment of Their Potential to Induce Microbial Resistance Compared to Conventional An

scientific article published on 25 May 2016

The C terminus of HspA--a potential target for native Ni(II) and Bi(III) anti-ulcer drugs

scientific article published on 25 May 2010

The Effect of Polymer Microstructure on Encapsulation Efficiency and Release Kinetics of Citropin 1.1 from the Poly(ε-caprolactone) Microparticles

scientific article published on 30 June 2018

The His-His sequence of the antimicrobial peptide demegen P-113 makes it very attractive ligand for Cu2+.

scientific article published on 8 January 2008

The Role of Counter-Ions in Peptides-An Overview

scientific article published on 03 December 2020

The antifungal activity of fatty acids of all stages of Sarcophaga carnaria L. (Diptera: Sarcophagidae).

scientific article published on 20 August 2013

The antifungal activity of the cuticular and internal fatty acid methyl esters and alcohols in Calliphora vomitoria

scientific article published on 8 April 2013

The antimicrobial peptide tachyplesin III coated alone and in combination with intraperitoneal piperacillin-tazobactam prevents ureteral stent Pseudomonas infection in a rat subcutaneous pouch model

scientific article published on 7 October 2007

The coordination abilities of the multiHis-cyclopeptide with two metal-binding centers--potentiometric and spectroscopic investigation

scientific article published on 01 October 2012

The cyclopeptides with the multi-His motif as ligands for copper(II)

scientific article published on 26 November 2010

The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1α expression in human endothelial cells through a negative feedback loop

scientific article

The influence of the cyclopeptide sequence on its coordination abilities towards Cu(II)

The lipopeptides Pal-Lys-Lys-NH(2) and Pal-Lys-Lys soaking alone and in combination with intraperitoneal vancomycin prevent vascular graft biofilm in a subcutaneous rat pouch model of staphylococcal infection

scientific article published on 31 March 2007

The major surface-metalloprotease of the parasitic protozoan, Leishmania, protects against antimicrobial peptide-induced apoptotic killing

scientific article published on 27 October 2006

The role of Glycyrrhizin, an inhibitor of HMGB1 protein, in anticancer therapy.

scientific article published on 25 August 2012

The –Cys–Cys– motif in Helicobacter pylori's Hpn and HspA proteins is an essential anchoring site for metal ions

scientific article published on 18 April 2011

Therapeutic efficacy of intraperitoneal polymyxin B and polymyxin-like peptides alone or combined with levofloxacin in rat models of septic shock ⬇️

scientific article published on January 1, 2002

Therapeutic efficacy of the magainin analogue MSI-78 in different intra-abdominal sepsis rat models

scientific article

Ultrashort Cationic Lipopeptides-Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis

scientific article published on 08 January 2020

Unveiling the fate of adhering bacteria to antimicrobial surfaces: expression of resistance-associated genes and macrophage-mediated phagocytosis

scientific article published on 31 July 2018

miR-200b downregulates CFTR during hypoxia in human lung epithelial cells.

scientific article

miR-429 regulates the transition between Hypoxia-Inducible Factor (HIF)1A and HIF3A expression in human endothelial cells

scientific article published on 8 March 2016

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