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List of works by Lourival Possani Postay

1,4-Benzoquinone antimicrobial agents against Staphylococcus aureus and Mycobacterium tuberculosis derived from scorpion venom

scientific article published on 10 June 2019

A Conus regularis conotoxin with a novel eight-cysteine framework inhibits CaV2.2 channels and displays an anti-nociceptive activity

scientific article published on 08 April 2013

A Deeper Examination of Thorellius atrox Scorpion Venom Components with Omic Techonologies

scientific article published on 12 December 2017

A K⁺ channel blocking peptide from the Cuban scorpion Rhopalurus garridoi

scientific article published on 25 October 2013

A Subfamily of Acidic α-K+ Toxins ⬇️

scientific article published on October 14, 2003

A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K+ channels.

scientific article

A large number of novel Ergtoxin-like genes and ERG K+-channels blocking peptides from scorpions of the genus Centruroides.

scientific article published in December 2002

A novel class of peptide found in scorpion venom with neurodepressant effects in peripheral and central nervous system of the rat.

scientific article

A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues

scientific article published in August 2005

A novel human recombinant antibody fragment capable of neutralizing Mexican scorpion toxins.

scientific article

A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new alpha-KTX subfamily

scientific article published on 4 January 2006

A paratransgenic strategy to block transmission of Xylella fastidiosa from the glassy-winged sharpshooter Homalodisca vitripennis

article

A pore forming peptide from spider Lachesana sp. venom induced neuronal depolarization and pain

scientific article published on 5 December 2014

A positive charge at the N-terminal segment of Discrepin increases the blocking effect of K+ channels responsible for the IA currents in cerebellum granular cells.

scientific article

A proteomic analysis of the early secondary molecular effects caused by Cn2 scorpion toxin on neuroblastoma cells

scientific article published on 2 May 2014

A selective blocker of Kv1.2 and Kv1.3 potassium channels from the venom of the scorpion Centruroides suffusus suffusus.

scientific article published on 22 August 2008

A single mutation in framework 2 of the heavy variable domain improves the properties of a diabody and a related single-chain antibody

article

A toxic fraction from scolopendra venom increases the basal release of neurotransmitters in the ventral ganglia of crustaceans

scientific article

Activation of skeletal ryanodine receptors by two novel scorpion toxins from Buthotus judaicus

scientific article published on 5 April 2004

Addition of positive charges at the C-terminal peptide region of CssII, a mammalian scorpion peptide toxin, improves its affinity for sodium channels Nav1.6

scientific article

Amino acid sequence and function of a new alpha-toxin from the Amazonian scorpion Tityus cambridgei

scientific article published in May 2004

An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis

scientific article published on 20 July 2018

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways

scientific article published on 24 May 2013

An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera.

scientific article

Analysis of the immune response induced by a scorpion venom sub-fraction, a pure peptide and a recombinant peptide, against toxin Cn2 of Centruroides noxius Hoffmann

scientific article published in March 2003

Antimicrobial peptides from arachnid venoms and their microbicidal activity in the presence of commercial antibiotics.

scientific article

Antivenom Evaluation by Electrophysiological Analysis.

scientific article published on 23 February 2017

Anuroctoxin, a new scorpion toxin of the alpha-KTx 6 subfamily, is highly selective for Kv1.3 over IKCa1 ion channels of human T lymphocytes

scientific article

Arthropod toxins acting on neuronal potassium channels

scientific article published on 20 September 2017

Autocrine-Based Selection of Drugs That Target Ion Channels from Combinatorial Venom Peptide Libraries.

scientific article

Bacterial expression, purification and functional characterization of a recombinant chimeric Fab derived from murine mAb BCF2 that neutralizes the venom of the scorpion Centruroides noxius hoffmann

scientific article published in January 2004

Biochemical and physiological characterization of a new Na(+)-channel specific peptide from the venom of the Argentinean scorpion Tityus trivittatus

scientific article published on 24 May 2014

Biochemical, genetic and physiological characterization of venom components from two species of scorpions: Centruroides exilicauda Wood and Centruroides sculpturatus Ewing

scientific article

Characterization of Sodium Channel Peptides Obtained from the Venom of the Scorpion Centruroides bonito

scientific article published in 2024

Characterization of a novel peptide toxin from Acanthoscurria paulensis spider venom: a distinct cysteine assignment to the HWTX-II family.

scientific article published on 29 March 2013

Characterization of hadrucalcin, a peptide from Hadrurus gertschi scorpion venom with pharmacological activity on ryanodine receptors

scientific article

Characterization of the venom from the Australian scorpion Urodacus yaschenkoi: Molecular mass analysis of components, cDNA sequences and peptides with antimicrobial activity

scientific article

Characterization of venom components from the scorpion Androctonus crassicauda of Turkey: peptides and genes.

scientific article published on 25 April 2006

Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum

scientific article

Cn11, the first example of a scorpion toxin that is a true blocker of Na(+) currents in crayfish neurons.

scientific article

Comparative assessment of the VH-VL and VL-VH orientations of single-chain variable fragments of scorpion toxin-neutralizing antibodies

scientific article published on 29 April 2020

Comparative proteomic analysis of male and female venoms from the Cuban scorpion Rhopalurus junceus

scientific article

Construction and expression of a single-chain variable fragment antibody against chicken DEC 205 for targeting the bacterial expressed hemagglutinin-neuraminidase of Newcastle disease virus

scientific article published on 06 May 2019

Current views on scorpion toxins specific for K+-channels

scientific article

Discrepin, a new peptide of the sub-family alpha-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K+ -channels (IA currents) of cerebellum granular cells

scientific article

Dissecting Toxicity: The Venom Gland Transcriptome and the Venom Proteome of the Highly Venomous Scorpion Centruroides limpidus (Karsch, 1879).

scientific article published on 30 April 2019

Disulfide bridges and blockage of Shaker B K(+)-channels by another butantoxin peptide purified from the Argentinean scorpion Tityus trivittatus.

scientific article

Eastern coral snake Micrurus fulvius venom toxicity in mice is mainly determined by neurotoxic phospholipases A2.

scientific article published on 5 March 2014

Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin

scientific article published on 09 February 2013

Evaluation of three different formats of a neutralizing single chain human antibody against toxin Cn2: neutralization capacity versus thermodynamic stability

scientific article published on 28 January 2012

Expanding the scorpion toxin alpha-KTX 15 family with AmmTX3 from Androctonus mauretanicus

scientific article

Experimental envenoming of mice with venom from the scorpion Centruroides limpidus limpidus: differences in mortality and symptoms with and without antibody therapy relating to differences in age, sex and strain of mouse

scientific article published in June 2003

Exploiting cross-reactivity to neutralize two different scorpion venoms with one single chain antibody fragment

scientific article

Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels

scientific article

Four disulfide-bridged scorpion beta neurotoxin CssII: heterologous expression and proper folding in vitro

scientific article published on May 2007

From noxiustoxin to scorpine and possible transgenic mosquitoes resistant to malaria

scientific article

Functional and immuno-reactive characterization of a previously undescribed peptide from the venom of the scorpion Centruroides limpidus

scientific article published on 18 November 2016

Gene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae

scientific article

General biochemical and immunological characterization of the venom from the scorpion Tityus trivittatus of Argentina

scientific article published on 23 August 2009

Generation of a Broadly Cross-Neutralizing Antibody Fragment against Several Mexican Scorpion Venoms

article

Global transcriptome analysis of the scorpion Centruroides noxius: new toxin families and evolutionary insights from an ancestral scorpion species

scientific article (publication date: 2012)

Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures

scientific article published on 01 November 2019

Heterologous expressed toxic and non-toxic peptide variants of toxin CssII are capable to produce neutralizing antibodies against the venom of the scorpion Centruroides suffusus suffusus.

scientific article

Heterologous expression of a gene that codes for Pg8, a scorpion toxin of Parabuthus granulatus, capable of generating protecting antibodies in mice

scientific article

HgeTx1, the first K+-channel specific toxin characterized from the venom of the scorpion Hadrurus gertschi Soleglad

scientific article

Identification and phylogenetic analysis of Tityus pachyurus and Tityus obscurus novel putative Na+-channel scorpion toxins

scientific article published on 15 February 2012

Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom.

scientific article published on 5 September 2012

Immunology of scorpion toxins and perspectives for generation of anti-venom vaccines

scientific article published in May 2005

Imperatoxin A, a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca-Release Channels/Ryanodine Receptors

scientific article

In Silico Identification of Protein Disulfide Isomerase Gene Families in the De Novo Assembled Transcriptomes of Four Different Species of the Genus Conus

scientific article published on 9 February 2016

Inhibition of the collapse of the Shaker K+ conductance by specific scorpion toxins.

scientific article

Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2

scientific article

Interaction of the scorpion toxin discrepin with Kv4.3 channels and A-type K+ channels in cerebellum granular cells

scientific article published in September 2014

Isolation and characterization of a human antibody fragment specific for Ts1 toxin from Tityus serrulatus scorpion ⬇️

scientific article published on May 19, 2011

Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels

scientific article published on 3 March 2007

Isolation and characterization of two novel scorpion toxins: The alpha-toxin-like CeII8, specific for Na(v)1.7 channels and the classical anti-mammalian CeII9, specific for Na(v)1.4 channels.

scientific article published on 19 June 2010

Isolation and molecular cloning of beta-neurotoxins from the venom of the scorpion Centruroides suffusus suffusus.

scientific article

Isolation of a long-lasting eag-related gene-type K+ current in MMQ lactotrophs and its accommodating role during slow firing and prolactin release.

scientific article

Isolation, amino acid sequence and biological characterization of an "aspartic-49" phospholipase A₂ from Bothrops (Rhinocerophis) ammodytoides venom.

scientific article published on 10 September 2012

Isolation, chemical and functional characterization of several new K(+)-channel blocking peptides from the venom of the scorpion Centruroides tecomanus

scientific article published on 24 February 2016

Mapping the binding site of a human ether-a-go-go-related gene-specific peptide toxin (ErgTx) to the channel's outer vestibule

scientific article published on 25 February 2002

Mapping the receptor site for ergtoxin, a specific blocker of ERG channels ⬇️

scientific article published on January 2, 2002

Mass fingerprinting and electrophysiological analysis of the venom from the scorpion Centruroides hirsutipalpus (Scorpiones: Buthidae).

scientific article published on 3 July 2018

Mass fingerprinting of the venom and transcriptome of venom gland of scorpion Centruroides tecomanus

scientific article

Mass spectrometry analysis, amino acid sequence and biological activity of venom components from the Brazilian scorpion Opisthacanthus cayaporum

scientific article

Membrane interactions and biological activity of antimicrobial peptides from Australian scorpion

scientific article published on 4 November 2013

MeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity

scientific article

Mining on scorpion venom biodiversity

scientific article

Molecular cloning and biochemical characterization of the first Na(+)-channel α-type toxin peptide (Acra4) from Androctonus crassicauda scorpion venom.

scientific article published on 5 February 2013

Molecular cloning and characterization of the alphaX subunit from CD11c/CD18 horse integrin

scientific article published on 3 January 2008

Molecular cloning and nucleotide sequence analysis of genes from a cDNA library of the scorpion Tityus discrepans

scientific article

Mortality and antibody responses of mice to three successive episodes of experimental scorpion (Centruroides limpidus limpidus) envenomation and immunological rescue.

scientific article

NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity.

scientific article published in June 2004

Negative-shift activation, current reduction and resurgent currents induced by β-toxins from Centruroides scorpions in sodium channels.

scientific article

Neotropical Rattlesnake (Crotalus simus) Venom Pharmacokinetics in Lymph and Blood Using an Ovine Model

scientific article published on 17 July 2020

New insights into the proteomic characterization of the coral snake Micrurus pyrrhocryptus venom

article

North American scorpion species of public health importance with a reappraisal of historical epidemiology

scientific article published on 06 August 2018

Novel alpha-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockade Kv1.3 over IKCa1 K+ channels of T cells

scientific article published on September 2005

Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.

scientific article

Novel interactions between K+ channels and scorpion toxins

scientific article

Novel paradigms on scorpion toxins that affects the activating mechanism of sodium channels

scientific article published on 27 September 2006

OcyKTx2, a new K⁺-channel toxin characterized from the venom of the scorpion Opisthacanthus cayaporum

scientific article published on 15 May 2013

Of Seven New K+ Channel Inhibitor Peptides of Centruroides bonito, α-KTx 2.24 Has a Picomolar Affinity for Kv1.2

scientific article published in 2023

On the evolution of invertebrate defensins

scientific article published on 01 June 2005

Optimal Neutralization of Centruroides noxius Venom Is Understood through a Structural Complex between Two Antibody Fragments and the Cn2 Toxin.

scientific article

Overview of scorpion toxins specific for Na+ channels and related peptides: biodiversity, structure-function relationships and evolution

scientific article

Overview of the Knottin scorpion toxin-like peptides in scorpion venoms: Insights on their classification and evolution

scientific article published on 14 July 2015

Oxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins.

scientific article

Peptides from the scorpion Vaejovis punctatus with broad antimicrobial activity.

scientific article published on 4 September 2015

Phaiodactylipin, a glycosylated heterodimeric phospholipase A from the venom of the scorpion Anuroctonus phaiodactylus.

scientific article published on April 2004

Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus

scientific article published in December 2004

Pore-forming spider venom peptides show cytotoxicity to hyperpolarized cancer cells expressing K+ channels: A lentiviral vector approach

scientific article published on 12 April 2019

Positive selection-guided mutational analysis revealing two key functional sites of scorpion ERG K(+) channel toxins

scientific article published on 24 October 2012

Potential of peptides selected from random phage-displayed libraries to mimic conformational epitopes: a study on scorpion toxin Cn2 and the neutralizing monoclonal antibody BCF2.

scientific article

Precursor De13.1 from Conus delessertii defines the novel G gene superfamily.

scientific article published on 20 January 2013

Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins

scientific article published in June 2006

Proteomic analysis of the venom and characterization of toxins specific for Na+ - and K+ -channels from the Colombian scorpion Tityus pachyurus

scientific article published on 26 August 2005

Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny.

scientific article

Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

scientific article

Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda.

scientific article

Purification of a specific inhibitor of pyroglutamyl aminopeptidase II from the marine annelide Hermodice carunculata. in vivo effects in rodent brain

scientific article published in January 2004

Recombinant expression of Intrepicalcin from the scorpion Vaejovis intrepidus and its effect on skeletal ryanodine receptors

scientific article published on 31 January 2017

Resurgent current and voltage sensor trapping enhanced activation by a beta-scorpion toxin solely in Nav1.6 channel. Significance in mice Purkinje neurons.

scientific article

Scorpion beta-toxins and voltage-gated sodium channels: interactions and effects ⬇️

scientific article published on January 1, 2013

Scorpion toxins from Tityus cambridgei that affect Na(+)-channels.

scientific article published on May 2002

Scorpion toxins that block T-type Ca2+ channels in spermatogenic cells inhibit the sperm acrosome reaction

article

Scorpion toxins that block transient currents (I(A)) of rat cerebellum granular cells

scientific article

Scorpion toxins to unravel the conundrum of ion channel structure and functioning

scientific article published on 30 April 2018

Scorpion venom components as potential candidates for drug development

scientific article

Scorpion venomics: a 2019 overview

scientific article published on 25 December 2019

Scorpions from Mexico: From Species Diversity to Venom Complexity

scientific article

Sequence analysis and phylogenetic relationship of genes encoding heterodimeric phospholipases A2 from the venom of the scorpion Anuroctonus phaiodactylus.

scientific article published on 24 March 2007

Smp76, a Scorpine-Like Peptide Isolated from the Venom of the Scorpion Scorpio maurus palmatus, with a Potent Antiviral Activity Against Hepatitis C Virus and Dengue Virus

scientific article published on 06 July 2019

Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus

scientific article

Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily.

scientific article

Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 sodium channels

scientific article

Species diversity and peptide toxins blocking selectivity of ether-a-go-go-related gene subfamily K+ channels in the central nervous system.

scientific article published on 23 February 2006

Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides noxius Hoffmann by a Human-derived Single-chain Antibody Fragment

scientific article

Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom

scientific article published on 25 December 2019

Structural characterization and phylogenetic relationships of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a Lys49 phospholipase A(2) homologue

scientific article

Structure, function, and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes

scientific article

Structure, molecular modeling, and function of the novel potassium channel blocker urotoxin isolated from the venom of the Australian scorpion Urodacus yaschenkoi.

scientific article published on 10 April 2014

Structure-function relationships of peptides forming the calcin family of ryanodine receptor ligands

scientific article published on May 2016

Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels

scientific article

Tetrapandins, a new class of scorpion toxins that specifically inhibit store-operated calcium entry in human embryonic kidney-293 cells.

scientific article published on 28 October 2003

The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function.

scientific article

The Cuban scorpion Rhopalurus junceus (Scorpiones, Buthidae): component variations in venom samples collected in different geographical areas ⬇️

scientific article (publication date: 20 May 2013)

The Diversified O-Superfamily in Presents a Conotoxin with Antimycobacterial Activity

scientific article published on 20 February 2019

The Dual α-Amidation System in Scorpion Venom Glands

scientific article published on 20 July 2019

The Enzymatic Core of Scorpion Venoms

scientific article published in 2022

The Kv1.3 channel blocker Vm24 enhances muscle glucose transporter 4 mobilization but does not reduce body-weight gain in diet-induced obese male rats

scientific article

The change of the scFv into the Fab format improves the stability and in vivo toxin neutralization capacity of recombinant antibodies

article by Veronica Quintero-Hernández et al published February 2007 in Molecular Immunology

The diversity of venom components of the scorpion species Paravaejovis schwenkmeyeri (Scorpiones: Vaejovidae) revealed by transcriptome and proteome analyses

scientific article published in September 2018

The past, present, and future of biotechnology in Mexico ⬇️

scientific article published on May 1, 2003

The unfulfilled promises of scorpion insectotoxins.

scientific article published on 17 June 2015

Toxin gamma from Tityus serrulatus scorpion venom plays an essential role in immunomodulation of macrophages

scientific article published in October 2007

Transcriptome analysis of scorpion species belonging to the Vaejovis genus

scientific article

Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones).

scientific article

Transcriptomic and Proteomic Analyses Reveal the Diversity of Venom Components from the Vaejovid Scorpion

scientific article published on 05 September 2018

Transcriptomic and proteomic analyses of the venom and venom glands of Centruroides hirsutipalpus, a dangerous scorpion from Mexico

scientific article published on 29 February 2020

Tst26, a novel peptide blocker of Kv1.2 and Kv1.3 channels from the venom of Tityus stigmurus

scientific article

Two new scorpion toxins that target voltage-gated Ca2+ and Na+ channels

scientific article published in December 2002

Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K(+)-channels with distinctly different affinities.

scientific article published on December 2002

Updating knowledge on new medically important scorpion species in Mexico

scientific article

Vejovine, a new antibiotic from the scorpion venom of Vaejovis mexicanus.

scientific article

Venom Gland Transcriptomic and Proteomic Analyses of the Enigmatic Scorpion Superstitionia donensis (Scorpiones: Superstitioniidae), with Insights on the Evolution of Its Venom Components

scientific article published on 9 December 2016

Venom components of the scorpion Centruroides limpidus modulate cytokine expression by T helper lymphocytes: Identification of ion channel-related toxins by mass spectrometry

scientific article published on 04 May 2020

Venom from the centipede Scolopendra viridis Say: purification, gene cloning and phylogenetic analysis of a phospholipase A2.

scientific article

Venom gland transcriptomic and venom proteomic analyses of the scorpion Megacormus gertschi Díaz-Najera, 1966 (Scorpiones: Euscorpiidae: Megacorminae).

scientific article

Venom proteomic and venomous glands transcriptomic analysis of the Egyptian scorpion Scorpio maurus palmatus (Arachnida: Scorpionidae).

scientific article

Venoms of Centruroides and Tityus species from Panama and their main toxic fractions.

scientific article published on 28 November 2017

Vm24, a natural immunosuppressive peptide, potently and selectively blocks Kv1.3 potassium channels of human T cells

scientific article

Whole Transcriptome of the Venom Gland from Urodacus yaschenkoi Scorpion

scientific article published on 28 May 2015

Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components.

scientific article published in December 2006

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