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List of works by Jakub Gołąb

5-Aza-2'-deoxycytidine potentiates antitumour immune response induced by photodynamic therapy.

scientific article

A New Inhibitor of Tubulin Polymerization Kills Multiple Cancer Cell Types and Reveals p21-Mediated Mechanism Determining Cell Death after Mitotic Catastrophe

scientific article published on 04 August 2020

A combination of retinoic acid and proteasome inhibitors for the treatment of leukemias is potentially dangerous

scientific article published on 01 September 1999

A common nonsense mutation of the BLM gene and prostate cancer risk and survival

scientific article published on 2 October 2013

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

scientific article

A single injection of immature dendritic cells is able to induce antitumour response against a murine colon adenocarcinoma with a low apoptotic index

scientific article published on 01 September 2002

AAF-cmk sensitizes tumor cells to trail-mediated apoptosis.

scientific article

Abstract 3975: Ovarian cancer cells release arginase-1-containing exosomes to suppress antitumor immune response

Abstract 5347: SK053, a small molecule inhibitor of enzymes involved in allosteric disulfide bonds formation, shows potent anti-leukemic effects and induces differentiation of human AML cells

Adenanthin targets proteins involved in the regulation of disulphide bonds.

scientific article published on 11 March 2014

Adenanthin, a new inhibitor of thiol-dependent antioxidant enzymes, impairs the effector functions of human natural killer cells

scientific article

Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer

Antitumor Activity of TLR7 Is Potentiated by CD200R Antibody Leading to Changes in the Tumor Microenvironment

scientific article published on 18 July 2018

Antitumor effects of photodynamic therapy are potentiated by 2-methoxyestradiol. A superoxide dismutase inhibitor.

scientific article published on 29 October 2002

Antitumor effects of the combination immunotherapy with interleukin-12 and tumor necrosis factor alpha in mice

scientific article published on 01 October 1997

Antitumor effects of the combination of cholesterol reducing drugs

scientific article published on 13 April 2011

Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin

scientific article published on 11 March 2015

Apoptosis induced in L1210 leukaemia cells by an inhibitor of the chymotrypsin-like activity of the proteasome

scientific article published on 01 January 1997

Application of a proteomic approach to identify proteins associated with primary graft non-function after liver transplantation.

scientific article

Augmented antitumor effects of combination therapy with interleukin-12, cisplatin, and tumor necrosis factor-alpha in a murine melanoma model

scientific article published on 01 November 1997

Augmented antitumour effects of combination therapy with TNP-470 and chemoimmunotherapy in mice.

scientific article published on 2 August 2002

B-cell receptor pathway inhibitors affect CD20 levels and impair antitumor activity of anti-CD20 monoclonal antibodies

scientific article published on 10 January 2014

Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase

scientific article published on 24 April 2020

Berberine, a natural cholesterol reducing product, exerts antitumor cytostatic/cytotoxic effects independently from the mevalonate pathway.

scientific article published on December 2006

Biodistribution and Efficacy Studies of the Proteasome Inhibitor BSc2118 in a Mouse Melanoma Model

scientific article

Bone marrow is the preferred site of memory CD4+ T cell proliferation during recovery from sepsis

scientific article published on 21 May 2020

Bortezomib modulates surface CD20 in B-cell malignancies and affects rituximab-mediated complement-dependent cytotoxicity

scientific article published on 3 March 2010

Cancer stem cells in haematological malignancies

scientific article

Cardiotoxicity of the anticancer therapeutic agent bortezomib.

scientific article

Cerivastatin demonstrates enhanced antitumor activity against human breast cancer cell lines when used in combination with doxorubicin or cisplatin.

scientific article published in May 2004

Cholesterol restricts lymphotoxin β receptor-triggered NF-κB signaling

scientific article published on 26 December 2019

Ciglitazone, an agonist of peroxisome proliferator-activated receptor gamma, exerts potentiated cytostatic/cytotoxic effects against tumor cells when combined with lovastatin.

scientific article published on January 2008

Combined effect of proteasome and calpain inhibition on cisplatin-resistant human melanoma cells

scientific article published on August 2006

CpG immunostimulatory oligodeoxynucleotide 1826 enhances antitumor effect of interleukin 12 gene-modified tumor vaccine in a melanoma model in mice

scientific article published on June 2004

Cyclosporine A and its non-immunosuppressive derivative NIM811 induce apoptosis of malignant melanoma cells in in vitro and in vivo studies.

scientific article published in October 2005

Danger signalling during cancer cell death: origins, plasticity and regulation.

scientific article published on 17 May 2013

Demethylating agent 5-aza-2'-deoxycytidine enhances expression of TNFRI and promotes TNF-mediated apoptosis in vitro and in vivo

scientific article published on September 2004

Determination of Aldehyde Dehydrogenase (ALDH) Isozymes in Human Cancer Samples - Comparison of Kinetic and Immunochemical Assays.

scientific article published on 31 December 2002

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases

scientific article published on 23 July 2019

Differential influence of pentoxifylline on murine colon adenocarcinoma- and melanoma-derived metastatic tumor development in lungs

scientific article published on May 2004

Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma.

scientific article published on 30 November 2015

Direct stimulation of macrophages by IL-12 and IL-18--a bridge too far?

scientific article published on June 2000

Direct tumor damage mechanisms of photodynamic therapy.

scientific article

Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors

scientific article published on 13 March 2020

Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis

scientific article published on 20 October 2020

Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase

scientific article published on 22 December 2017

Discussion on 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis

scientific article published on 01 November 2002

Dissection of CD20 regulation in lymphoma using RNAi

scientific article published on 18 August 2016

Drug delivery technologies and immunological aspects of photodynamic therapy

scientific article published on 13 April 2011

Effective chemo-immunotherapy of L1210 leukemia in vivo using interleukin-12 combined with doxorubicin but not with cyclophosphamide, paclitaxel or cisplatin

scientific article

Effective photoimmunotherapy of murine colon carcinoma induced by the combination of photodynamic therapy and dendritic cells

scientific article published on July 2004

Epigenetic remodeling combined with photodynamic therapy elicits anticancer immune responses

scientific article published on 15 May 2014

Erythropoietin prevents the development of interleukin-12-induced anemia and thrombocytopenia but does not decrease its antitumor activity in mice

scientific article published on 01 June 1998

Erythropoietin reduces cisplatin-induced neurotoxicity without impairment of cytotoxic effects against tumor cells

scientific article published on December 2007

Erythropoietin restores the antitumor effectiveness of photodynamic therapy in mice with chemotherapy-induced anemia.

scientific article

Exploring the anti-cancer activity of novel thiosemicarbazones generated through the combination of retro-fragments: dissection of critical structure-activity relationships

scientific article

Extracellular vesicles released by ovarian carcinoma contain arginase 1 that mitigates antitumor immune response

scientific article published on 20 August 2019

FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy.

scientific article published on 25 January 2018

G-CSF prevents the suppression of bone marrow hematopoiesis induced by IL-12 and augments its antitumor activity in a melanoma model in mice

scientific article published on 01 January 1998

GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy

scientific article published on 25 July 2013

Genetic modification of T cells improves the effectiveness of adoptive tumor immunotherapy.

scientific article published on 06 August 2010

Granulocyte colony-stimulating factor demonstrates antitumor activity in melanoma model in mice.

scientific article published in January 1998

Granulocyte-macrophage colony-stimulating factor potentiates antitumor activity of interleukin-12 in melanoma model in mice

scientific article published on 01 January 1998

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

HDAC6 inhibition upregulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies

scientific article

Heme oxygenase-1 protects tumor cells against photodynamic therapy-mediated cytotoxicity.

scientific article

IL-12 or IL-15, unlike IL-2, does not interact with histamine in augmenting cytotoxicity of splenocytes against melanoma cells and YAC-1 cells.

scientific article published on March 2002

Immunogenic cell death, DAMPs and anticancer therapeutics: an emerging amalgamation

scientific article

Immunoglobulin expression and the humoral immune response is regulated by the non-canonical poly(A) polymerase TENT5C

scientific article published on 27 April 2020

Improvement of anti-tumor activity of photodynamic therapy through inhibition of cytoprotective mechanism in tumor cells

Increased local vascular endothelial growth factor expression associated with antitumor activity of proteasome inhibitor.

scientific article published in March 2004

Induction of heme-oxygenase 1 requires the p38MAPK and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy

scientific article published on April 2007

Inhibition of IDO leads to IL-6-dependent systemic inflammation in mice when combined with photodynamic therapy

scientific article published on 28 February 2020

Inhibition of arginase modulates T-cell response in the tumor microenvironment of lung carcinoma

scientific article published in 2021

Inhibition of autophagy sensitizes cancer cells to Photofrin-based photodynamic therapy

scientific article published on 20 February 2018

Inhibition of cyclooxygenase-2 indirectly potentiates antitumor effects of photodynamic therapy in mice

scientific article published in November 2003

Inhibition of lymphangiogenesis impairs antitumour effects of photodynamic therapy and checkpoint inhibitors in mice

scientific article published on 11 July 2017

Inhibition of proteasome, apoptosis and sensitization to tumour necrosis factor alpha: do they always go together?

scientific article published on 01 January 1999

Inhibition of protein disulfide isomerase induces differentiation of acute myeloid leukemia cells

scientific article published on 12 July 2018

Inhibition of thioredoxin-dependent HO removal sensitizes malignant B-cells to pharmacological ascorbate

scientific article published on 29 November 2018

Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies.

scientific article

Interleukin 12 and indomethacin exert a synergistic, angiogenesis-dependent antitumor activity in mice

scientific article published on 01 February 2000

Interleukin 12-based immunotherapy improves the antitumor effectiveness of a low-dose 5-Aza-2'-deoxycitidine treatment in L1210 leukemia and B16F10 melanoma models in mice

scientific article published in August 2003

Interleukin 15 as a promising candidate for tumor immunotherapy

scientific article (publication date: April 2011)

Interleukin 18--interferon gamma inducing factor--a novel player in tumour immunotherapy?

scientific article

Investigation of cell death mechanisms in human lymphatic endothelial cells undergoing photodynamic therapy

scientific article published on 8 February 2016

Iron chelators in photodynamic therapy revisited: synergistic effect by novel highly active thiosemicarbazones

scientific article

Lovastatin potentiates antitumor effects of saquinavir against human lymphoma cells.

scientific article

Low dose of GRP78-targeting subtilase cytotoxin improves the efficacy of photodynamic therapy in vivo

scientific article published on April 2016

MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

scientific article

Melanoma targeting with the loco-regional chemotherapeutic, Melphalan: From cell death to immunotherapeutic efficacy

scientific article published on 29 May 2015

Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

scientific article

Molecular mechanisms of the antitumor effects of anti-CD20 antibodies

scientific article published on January 2011

Myeloid Cell-Derived Arginase in Cancer Immune Response

scientific article published on 15 May 2020

Natural mechanisms protecting against cancer.

scientific article published on December 2003

Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis

scientific article published on 28 July 2013

PDT-induced inflammatory and host responses ⬇️

scientific article published on January 24, 2011

Pentoxifylline inhibits leukocyte infiltration and splenocyte cytotoxicity against murine colon adenocarcinoma.

scientific article

Pentoxifylline promotes development of murine colon adenocarcinoma-derived metastatic tumors in liver

scientific article published on November 2003

Photochemical delivery of bleomycin induces T-cell activation of importance for curative effect and systemic anti-tumor immunity

scientific article published on 14 October 2017

Photodynamic therapy of cancer: an update

scientific article published on 26 May 2011

Photodynamic therapy-driven induction of suicide cytosine deaminase gene

scientific article published on 12 October 2009

Photodynamic therapy: illuminating the road from cell death towards anti-tumour immunity

scientific article published on September 2010

Pioglitazone, a PPAR-gamma ligand, exerts cytostatic/cytotoxic effects against cancer cells, that do not result from inhibition of proteasome.

scientific article

Potent but transient immunosuppression of T-cells is a general feature of CD71<sup>+</sup> erythroid cells

scientific article published on 10 December 2021

Potential antitumor effects of statins (Review).

scientific article

Potentiated antitumor effects of a combination therapy with a farnesyltransferase inhibitor L-744,832 and butyrate in vitro.

scientific article published on May 2004

Potentiated antitumor effects of butyrate and actinomycin D in melanoma model in mice.

scientific article published in January 2002

Potentiated antitumor effects of interleukin 12 and interferon alpha against B16F10 melanoma in mice

scientific article published on 01 January 2001

Potentiated antitumor effects of interleukin 12 and matrix metalloproteinase inhibitor batimastat against B16F10 melanoma in mice

scientific article published on 01 January 2000

Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.

scientific article published on June 2007

Potentiated antitumour effects of cisplatin and lovastatin against MmB16 melanoma in mice

scientific article published on 01 February 1998

Potentiatied anti-tumor effectiveness of combined therapy with interleukin-12 and mitoxantrone of L1210 leukemia in vivo

scientific article published on 01 January 2000

Potentiating antitumor effects of a combination therapy with lovastatin and butyrate in the Lewis lung carcinoma model in mice

scientific article published in February 2002

Potentiation of antitumor effects of IL-12 in combination with paclitaxel in murine melanoma model in vivo

scientific article published on 01 December 1999

Potentiation of antitumor effects of tumor necrosis factor alpha and interferon gamma by macrophage-colony-stimulating factor in a MmB16 melanoma model in mice

scientific article published on 01 May 1995

Potentiation of the anti-tumor effect of actinomycin D by tumor necrosis factor alpha in mice: correlation between in vitro and in vivo results

scientific article published on May 1996

Prenyltransferases regulate CD20 protein levels and influence anti-CD20 monoclonal antibody-mediated activation of complement-dependent cytotoxicity

scientific article

Prospects for p53-based cancer therapy.

scientific article

Proteasome inhibition potentiates antitumor effects of photodynamic therapy in mice through induction of endoplasmic reticulum stress and unfolded protein response

scientific article published on 12 May 2009

Proteasome inhibitors in the treatment of cancer

scientific article published in July 2003

Proteolytic pathways involved in modulation of CD20 levels

article published in 2010

Proteolytic pathways involved in modulation of CD20 levels

scientific article published on 3 August 2010

Re: Macrophage role in the anti-prostate cancer response to one class of antiangiogenic agents

scientific article published on 01 May 1999

Role of the ubiquitin-proteasome pathway in the diagnosis of human diseases

scientific article published in February 2004

SK053 triggers tumor cells apoptosis by oxidative stress-mediated endoplasmic reticulum stress

scientific article

Selection of an optimal promoter for gene transfer in normal B cells.

scientific article

Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma.

scientific article

Sorafenib improves rituximab and ofatumumab efficacy by decreasing the expression of complement regulatory proteins

scientific article published on 10 April 2015

Statins can modulate effectiveness of antitumor therapeutic modalities

scientific article published on January 2010

Statins impair antitumor effects of rituximab by inducing conformational changes of CD20

scientific article

Statins impair glucose uptake in human cells

scientific article published on 26 April 2014

Statins impair glucose uptake in tumor cells

scientific article published in April 2012

Statins potentiate cytostatic/cytotoxic activity of sorafenib but not sunitinib against tumor cell lines in vitro

scientific article

Stimulation of TNF-alpha production by 2-(1-adamantylamino)-6-methylpyridine (AdAMP) - a novel immunomodulator with potential application in tumour immunotherapy.

scientific article

Studies of the synthesis of all stereoisomers of MG-132 proteasome inhibitors in the tumor targeting approach

scientific article published in February 2010

Studies toward novel peptidomimetic inhibitors of thioredoxin-thioredoxin reductase system

scientific article

Subtherapeutic doses of interleukin-15 augment the antitumor effect of interleukin-12 in a B16F10 melanoma model in mice

scientific article published on 01 September 1999

Synergistic antitumor activity of tumor necrosis factor-alpha and lovastatin against MmB16 melanoma in mice

scientific article published on 01 January 1995

Synergistic antitumor effects of a selective proteasome inhibitor and TNF in mice

scientific article published on 01 May 2000

Systematic Evaluation of Chemically Distinct Tissue Optical Clearing Techniques in Murine Lymph Nodes

scientific article published on 17 January 2020

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma

scientific article published on 28 December 2017

Targeting Epigenetic Processes in Photodynamic Therapy-Induced Anticancer Immunity

scientific article (publication date: 2015)

Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents

scientific article published on 05 October 2018

Targeting the thioredoxin system as a novel strategy against B-cell acute lymphoblastic leukemia

scientific article published on 05 April 2019

Technology evaluation: SB-485232, GlaxoSmithKline.

scientific article

The G84E mutation in the HOXB13 gene is associated with an increased risk of prostate cancer in Poland

scientific article

The dual role of tumor lymphatic vessels in dissemination of metastases and immune response development

scientific article

The influence of photodynamic therapy on the immune response.

scientific article

The possible role of factor H in colon cancer resistance to complement attack.

scientific article published on May 2008

The potentiated antileukemic effects of doxorubicin and interleukin-12 combination are not dependent on nitric oxide production

scientific article published on 01 December 1999

The presence of prostate cancer at biopsy is predicted by a number of genetic variants

scientific article published on 16 September 2013

The pro-tumor effect of CD200 expression is not mimicked by agonistic CD200R antibodies

scientific article published in PLoS ONE

The variant allele of the rs188140481 polymorphism confers a moderate increase in the risk of prostate cancer in Polish men

scientific article published in March 2015

Tissue clearing-based method for unobstructed 3D imaging of mouse penis with subcellular resolution

scientific article published on 30 April 2020

Topical ALA-PDT modifies neutrophils' chemiluminescence, lymphocytes' interleukin-1beta secretion and serum level of transforming growth factor beta1 in patients with nonmelanoma skin malignancies A clinical study

scientific article

Upregulation of MLK4 promotes migratory and invasive potential of breast cancer cells.

scientific article

Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice

scientific article

[Antitumor effects of sulindac in ovarian cell cultures].

scientific article published in March 2011

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