List of works by Arlette Darfeuille-Michaud

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

scientific article

Abnormalities in the handling of intracellular bacteria in Crohn's disease: a link between infectious etiology and host genetic susceptibility

scientific article published on 29 July 2008

Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion

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Activation of the EIF2AK4-EIF2A/eIF2α-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasive Escherichia coli infection

scientific article published on 17 March 2016

Adherent-invasive Escherichia coli and Crohnʼs disease

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Adherent-invasive Escherichia coli in inflammatory bowel disease

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Adherent-invasive Escherichia coli: a putative new E. coli pathotype associated with Crohn's disease

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Analysis of the σE regulon in Crohn's disease-associated Escherichia coli revealed involvement of the waaWVL operon in biofilm formation

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Bacteriophages Targeting Adherent Invasive Escherichia coli Strains as a Promising New Treatment for Crohn's Disease

scientific article published on 27 January 2017

Biofilm formation as a novel phenotypic feature of adherent-invasive Escherichia coli (AIEC)

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CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease

scientific article published on 24 May 2007

Chitin-binding domains of Escherichia coli ChiA mediate interactions with intestinal epithelial cells in mice with colitis

scientific article published on 16 May 2013

Colon cancer-associated B2 Escherichia coli colonize gut mucosa and promote cell proliferation

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Complete genome sequence of Crohn's disease-associated adherent-invasive E. coli strain LF82.

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Crohn disease--associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae

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Crohn disease: a current perspective on genetics, autophagy and immunity

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Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM.

scientific article published on 08 September 2009

Crohn's disease-associated adherent invasive Escherichia coli modulate levels of microRNAs in intestinal epithelial cells to reduce autophagy

scientific article published on 19 October 2013

Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly

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Enterohemorrhagic Escherichia coli pathogenesis: role of Long polar fimbriae in Peyer's patches interactions

scientific article published on 20 March 2017

Epidemiological study of pap genes among diarrheagenic or septicemic Escherichia coli strains producing CS31A and F17 adhesins and characterization of Pap(31A) fimbriae

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Etiology of Crohn's disease: many roads lead to autophagy

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Exosomes Released from Cells Infected with Crohn's Disease-associated Adherent-Invasive Escherichia coli Activate Host Innate Immune Responses and Enhance Bacterial Intracellular Replication

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Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease

scientific article published on 03 October 2013

Guidelines for the use and interpretation of assays for monitoring autophagy

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

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HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC).

scientific article published in January 2014

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

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High prevalence of mucosa-associated E. coli producing cyclomodulin and genotoxin in colon cancer

scientific article published on 14 February 2013

Infectious etiopathogenesis of Crohn's disease

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Intracellular colon cancer-associated Escherichia coli promote protumoral activities of human macrophages by inducing sustained COX-2 expression

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Involvement of lipoprotein NlpI in the virulence of adherent invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease

scientific article published on May 2004

Lactobacillus casei DN-114 001 inhibits the ability of adherent-invasive Escherichia coli isolated from Crohn's disease patients to adhere to and to invade intestinal epithelial cells

scientific article published on June 2005

Molecular diversity of Escherichia coli in the human gut: new ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohn's disease

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Pathogenic agents in inflammatory bowel diseases

scientific article published on July 2008

Point mutations in FimH adhesin of Crohn's disease-associated adherent-invasive Escherichia coli enhance intestinal inflammatory response

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Replication of Crohn's disease-associated AIEC within macrophages is dependent on TNF-α secretion

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Risk predisposition for Crohn disease: a "ménage à trois" combining IRGM allele, miRNA and xenophagy

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Role of bacteria in the etiopathogenesis of inflammatory bowel disease

scientific article published on November 2007

Role of decreased levels of Fis histone-like protein in Crohn's disease-associated adherent invasive Escherichia coli LF82 bacteria interacting with intestinal epithelial cells

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Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli

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Role of microRNAs in the immune system, inflammation and cancer

scientific article published on May 2013

Similarity and divergence among adherent-invasive Escherichia coli and extraintestinal pathogenic E. coli strains

scientific article published on 14 October 2009

Strong decrease in invasive ability and outer membrane vesicle release in Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 with the yfgL gene deleted

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Subversion of autophagy in adherent invasive Escherichia coli-infected neutrophils induces inflammation and cell death

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The bacterial genotoxin colibactin promotes colon tumor growth by modifying the tumor microenvironment

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The endoplasmic reticulum stress response chaperone: Gp96, a host receptor for Crohn disease-associated adherent-invasive Escherichia coli

scientific article published on March 2011

The oxidoreductase DsbA plays a key role in the ability of the Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 to resist macrophage killing

scientific article published on 20 April 2007

The role of anti(myco)bacterial interventions in the management of IBD: is there evidence at all?

scientific article published on 12 July 2012

The σE pathway is involved in biofilm formation by Crohn's disease-associated adherent-invasive Escherichia coli

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Thiazolylaminomannosides as potent antiadhesives of type 1 piliated Escherichia coli isolated from Crohn's disease patients

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Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice

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Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation

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