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Authors whose works are in public domain in at least one jurisdiction

List of works by Veit Hornung

51-100 of 184 results

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses.

scientific article published on 19 February 2016

MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment

scientific article

Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I.

scientific article

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.

scientific article published on 19 January 2012

cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders

scientific article published on 13 September 2017

Guanylate Binding Protein (GBP) 5 Is an Interferon-Inducible Inhibitor of HIV-1 Infectivity

scientific article published on 15 March 2016

Species-specific detection of the antiviral small-molecule compound CMA by STING

scientific article

Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference

scientific article

cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells

scientific article

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

scientific article

Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.

scientific article

T cell-independent, TLR-induced IL-12p70 production in primary human monocytes

scientific article published on June 2006

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice.

scientific article published on 2 June 2016

OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines

scientific article published on 3 September 2014

RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells

scientific article

Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation

scientific article

CpG-A and CpG-B oligonucleotides differentially enhance human peptide-specific primary and memory CD8+ T-cell responses in vitro

article

ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA.

scientific article published on 26 November 2015

CpG ODN enhance antigen-specific NKT cell activation via plasmacytoid dendritic cells

scientific article published in August 2005

Postoperative ileus involves interleukin-1 receptor signaling in enteric glia

scientific article published on 22 September 2013

Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production

scientific article published on July 2016

SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.

scientific article

ATP-dependent effector-like functions of RIG-I-like receptors

scientific article

RNA recognition via TLR7 and TLR8.

scientific article published on January 2008

Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA.

scientific article

CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism

scientific article published on 28 July 2016

Viral 5'-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses

scientific article published on 01 December 2008

Induction of type I IFNs by intracellular DNA-sensing pathways

scientific article published on 27 March 2012

AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis

scientific article published on 26 June 2015

Self-priming determines high type I IFN production by plasmacytoid dendritic cells

scientific article published on 16 January 2014

Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.

scientific article published on 05 January 2016

Immunostimulatory RNA Blocks Suppression by Regulatory T Cells

scientific article published on 04 December 2009

Phosphorylation of murine SAMHD1 regulates its antiretroviral activity

scientific article

Synthesis of an arrayed sgRNA library targeting the human genome

scientific article published on October 8, 2015

Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes

scientific article published on 20 October 2014

Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.

scientific article

Inflammasome-Dependent Induction of Adaptive NK Cell Memory

scientific article published on 6 June 2016

Pore formation by GSDMD is the effector mechanism of pyroptosis

scientific article published on 29 August 2016

Trif is not required for immune complex glomerulonephritis: dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif

scientific article published on 21 January 2009

Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations.

scientific article

Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases

scientific article published on 27 December 2018

iGLuc: a luciferase-based inflammasome and protease activity reporter

scientific article

Immunology in clinic review series; focus on autoinflammatory diseases: inflammasomes: mechanisms of activation

scientific article

Immunostimulatory RNA oligonucleotides induce an effective antitumoral NK cell response through the TLR7.

scientific article

Nucleic acid driven sterile inflammation

scientific article published on 19 January 2013

Aging-Associated TNF Production Primes Inflammasome Activation and NLRP3-Related Metabolic Disturbances.

scientific article published on 26 August 2016

Alternative inflammasome activation enables IL-1β release from living cells

scientific article published on 11 November 2016

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice

scientific article published on 26 June 2015

SnapShot: Nucleic Acid Immune Sensors, Part 1

scientific article published on November 20, 2014

Cre-dependent DNA recombination activates a STING-dependent innate immune response

scientific article published on 10 May 2016