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List of works by Anne Searls De Groot

2007 highlights of advances in the pharmaceutical sciences: An American Association of Pharmaceutical Scientists (AAPS) perspective

scientific article published on 22 June 2007

3 Prediction and Determination of MHC Ligands and T-cell Epitopes

8th vaccine renaissance: A creative nexus for vaccine developers

scientific article published on 9 July 2015

A Standard of HIV Care for Incarcerated Women: Northeastern United States' Experiences

article

A comparison of two methods for T cell epitope mapping: "cell free" in vitro versus immunoinformatics.

scientific article published on May 2011

A cross-sectional study to assess HPV knowledge and HPV vaccine acceptability in Mali

scientific article

A decade of partnering to stop HIV in West Africa: GAIA VF prevention, education, access to care and vaccine trial site development in Bamako, Mali.

scientific article published on 13 September 2012

A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses

scientific article

A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.

scientific article

A method for individualizing the prediction of immunogenicity of protein vaccines and biologic therapeutics: individualized T cell epitope measure (iTEM).

scientific article published on 18 July 2010

A nurse-run walk-in clinic: cost-effective alternative to non-urgent emergency department use by the uninsured

scientific article published on December 2013

A prime-boost concept using a T-cell epitope-driven DNA vaccine followed by a whole virus vaccine effectively protected pigs in the pandemic H1N1 pig challenge model

scientific article published on 24 June 2019

Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes"

scientific article

Adeno-associated virus mediated delivery of Tregitope 167 ameliorates experimental colitis

scientific article published on August 2012

Agility in adversity: Vaccines on Demand

scientific article

Alarming statistics about incarcerated women

scientific article published on 01 July 2001

An HLA-directed molecular and bioinformatics approach identifies new HLA-A11 HIV-1 subtype E cytotoxic T lymphocyte epitopes in HIV-1-infected Thais

scientific article published in May 2001

An Integrated Genomic and Immunoinformatic Approach to H. pylori Vaccine Design.

scientific article

An immunoinformatic approach for identification of Trypanosoma cruzi HLA-A2-restricted CD8(+) T cell epitopes.

scientific article

An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice

scientific article published on 2 June 2017

Analysis of ChimeriVax Japanese Encephalitis Virus envelope for T-cell epitopes and comparison to circulating strain sequences

scientific article published on 29 September 2007

Analyzing Mycobacterium tuberculosis proteomes for candidate vaccine epitopes

scientific article published on 25 December 2004

Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes

scientific article

Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma

scientific article

Assessment of hypertension guidelines adherence at a free clinic serving a predominantly Latino population in Providence, RI.

scientific article

Bamako, not Timbuktu

scientific article published on March 1, 2003

Barriers to Health Insurance Pre- and Post-Affordable Care Act Implementation in Providence, RI.

scientific article

Beyond humanization and de-immunization: tolerization as a method for reducing the immunogenicity of biologics

scientific article

Bioinformatics tools for identifying class I-restricted epitopes

scientific article

Bridging the [Health Equity] Gap at a Free Clinic for Uninsured Residents of Rhode Island

article

C3d adjuvant effects are mediated through the activation of C3d-specific autoreactive T cells

scientific article

CHOPPI: a web tool for the analysis of immunogenicity risk from host cell proteins in CHO-based protein production.

scientific article

Can we prevent immunogenicity of human protein drugs?

scientific article published on January 2010

Challenges and opportunities for HIV care in jails and prisons in the United States

article

Clinical trials in correctional settings: proceedings of a conference held in Providence, Rhode Island, October 13-15, 1999.

scientific article published in December 2000

Clinical validation of the "in silico" prediction of immunogenicity of a human recombinant therapeutic protein

scientific article published on 9 May 2007

Clínica Esperanza/Hope Clinic clinical outcomes review: February-July 2011

scientific article published on October 1, 2011

Co-infection with Mycobacterium tuberculosis and HIV in high risk clinical care setting in Rhode Island

scientific article published in April 1998

Community clinic-based lifestyle change for prevention of metabolic syndrome: Rationale, design and methods of the 'Vida Sana/healthy life' program

Community-based childhood obesity prevention intervention for parents improves health behaviors and food parenting practices among Hispanic, low-income parents.

scientific article published on 27 March 2018

Computational vaccinology and the ICoVax 2012 workshop

scientific article published on 8 March 2013

Conservation of HIV-1 T cell epitopes across time and clades: validation of immunogenic HLA-A2 epitopes selected for the GAIA HIV vaccine

scientific article

Conservation of HIV-1 T cell epitopes across time and clades: validation of immunogenic HLA-A2 epitopes selected for the GAIA HIV vaccine

article

Correction: A Dominant EV71-Specific CD4+ T Cell Epitope Is Highly Conserved among Human Enteroviruses.

scientific article published on 13 January 2014

Coupling sensitive in vitro and in silico techniques to assess cross-reactive CD4(+) T cells against the swine-origin H1N1 influenza virus

scientific article

Critical Prevention, Critical Care: Gynecological and Obstetrical Aspects of Comprehensive HIV Prevention and Treatment Among Incarcerated Women

article

Cross-conservation of T-cell epitopes: now even more relevant to (H7N9) influenza vaccine design.

scientific article

De-immunized and Functional Therapeutic (DeFT) versions of a long lasting recombinant alpha interferon for antiviral therapy

scientific article published on 9 January 2017

Dendritic cell-mediated, DNA-based vaccination against hepatitis C induces the multi-epitope-specific response of humanized, HLA transgenic mice

scientific article

Design of a multiepitopic Zaire ebolavirus protein and its expression in plant cells

article

Developing an epitope-driven tuberculosis (TB) vaccine

scientific article

Development and validation of an epitope prediction tool for swine (PigMatrix) based on the pocket profile method

scientific article published on 15 September 2015

Diversity of Francisella tularensis Schu4 antigens recognized by T lymphocytes after natural infections in humans: Identification of candidate epitopes for inclusion in a rationally designed tularemia vaccine

scientific article published on 22 January 2007

Do Tregitopes have the potential to impact the current treatment landscape of autoimmune diseases?

scientific article

Editorial comment: HIV testing in prisons and jails--providing the carrot with the stick.

scientific article published in September 2007

Effect of HLA DR epitope de-immunization of Factor VIII in vitro and in vivo.

scientific article published on 8 December 2011

Efficacy of novel plasmid DNA encoding vaccinia antigens in improving current smallpox vaccination strategy

article by Miguel Otero et al published May 2006 in Vaccine

Elevated antigen-specific Th2 type response is associated with the poor prognosis of hand, foot and mouth disease

scientific article published on 22 July 2013

Emerging vaccine informatics

scientific article

Engineering immunogenic consensus T helper epitopes for a cross-clade HIV vaccine

scientific article published in December 2004

Epitope recognition in HLA-DR3 transgenic mice immunized to TSH-R protein or peptides

scientific article

Epitope-based vaccination against pneumonic tularemia

scientific article published on 17 July 2009

Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice

scientific article published in June 2007

Evaluating short-term patient outcomes after HIV care interventions in a low resource setting: preparing for an HIV vaccine trial site in Bamako, Mali

scientific article published on 13 September 2012

Evolutionary deimmunization: An ancillary mechanism for self-tolerance?

article

Exploring the immunome: A brave new world for human vaccine development

scientific article

Fifth Vaccine Renaissance introduction

scientific article published on July 1, 2012

Four Years of CHEER: Cost and QALY Savings of a Free Nurse-run Walk-in Clinic Serving an Uninsured, Predominantly Spanish-speaking Immigrant Population in Providence

scientific article published on 01 January 2019

From genome to vaccine: in silico predictions, ex vivo verification.

scientific article

From genome to vaccine—new immunoinformatics tools for vaccine design

article by Anne Searls De Groot & Jay A Berzofsky published December 2004 in Methods

Further confirmation of broadly conserved, highly immunogenic cross-clade HIV CTL epitopes for inclusion in the GAIA HIV vaccine.

scientific article published on 13 September 2012

Further progress on defining highly conserved immunogenic epitopes for a global HIV vaccine: HLA-A3-restricted GAIA vaccine epitopes

article

Genome-derived vaccines

scientific article published on February 2004

Greater CD8+ TCR heterogeneity and functional flexibility in HIV-2 compared to HIV-1 infection

scientific article published in July 2003

H7N9 T-cell epitopes that mimic human sequences are less immunogenic and may induce Treg-mediated tolerance.

scientific article

HCV epitope, homologous to multiple human protein sequences, induces a regulatory T cell response in infected patients

scientific article

HIV clinical trials in correctional settings: right or retrogression?

scientific article

HIV infection among incarcerated women: epidemic behind bars.

scientific article

HIV vaccine development by computer assisted design: the GAIA vaccine

scientific article (publication date: 18 March 2005)

HIV-1 Vaccine Trials: Evolving Concepts and Designs

scientific article

HIV-free children born to HIV-seropositive mothers in Bamako, Mali: a six-year perspective on providing MTCTP at the front line of AIDS.

scientific article published on 13 September 2012

HLA- and genotype-based risk assessment model to identify infantile onset pompe disease patients at high-risk of developing significant anti-drug antibodies (ADA)

scientific article published on 31 January 2019

HLA-A2-restricted CD8+-cytotoxic-T-cell responses to novel epitopes in Mycobacterium tuberculosis superoxide dismutase, alanine dehydrogenase, and glutamine synthetase

scientific article published on April 2004

HPV knowledge and vaccine acceptance in an uninsured Hispanic population in Providence, RI.

scientific article

Harnessing the power of genomics and immunoinformatics to produce improved vaccines

scientific article

Health care access, utilization, and needs in a predominantly Latino immigrant community in Providence, Rhode Island.

scientific article

HelicoVax: epitope-based therapeutic Helicobacter pylori vaccination in a mouse model

scientific article

Hit-and-run, hit-and-stay, and commensal bacteria present different peptide content when viewed from the perspective of the T cell.

scientific article

How the SARS vaccine effort can learn from HIV?speeding towards the future, learning from the past

scientific article published on October 1, 2003

Human immune responses to H. pylori HLA Class II epitopes identified by immunoinformatic methods.

scientific article

Human immunodeficiency virus reverse transcriptase T helper epitopes identified in mice and humans: correlation with a cytotoxic T cell epitope.

scientific article published in December 1991

ICoVax 2013: the 3rd ISV Pre-conference Computational Vaccinology Workshop

scientific article published on 19 March 2014

Identification and retrospective validation of T-cell epitopes in the hepatitis C virus genotype 4 proteome: an accelerated approach toward epitope-driven vaccine development.

scientific article published on January 2014

Identification of genome-derived vaccine candidates conserved between human and mouse-adapted strains of H. pylori

scientific article published in May 2008

Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV

scientific article published on 26 December 2007

Immune camouflage: relevance to vaccines and human immunology

scientific article published on January 2014

Immune escape and immune camouflage may reduce the efficacy of RTS,S vaccine in Malawi

scientific article published on 08 March 2019

Immunization with cross-conserved H1N1 influenza CD4+ T-cell epitopes lowers viral burden in HLA DR3 transgenic mice

scientific article

Immuno-informatics: Mining genomes for vaccine components

scientific article

Immunogenic Consensus Sequence T helper Epitopes for a Pan-Burkholderia Biodefense Vaccine.

scientific article

Immunogenicity Screening Usingin Silico Methods: Correlation between T-Cell Epitope Content and Clinical Immunogenicity of Monoclonal Antibodies

article

Immunogenicity and immune modulatory effects of in silico predicted L. donovani candidate peptide vaccines

scientific article

Immunogenicity of Therapeutic Fusion Proteins: Contributory Factors and Clinical Experience

Immunogenicity of protein therapeutics

scientific article (publication date: November 2007)

Immunoinformatic analysis of Chinese hamster ovary (CHO) protein contaminants in therapeutic protein formulations

article

Immunoinformatic approach to a multi-pathogen genome-derived epitope-driven vaccine

Immunoinformatic comparison of T-cell epitopes contained in novel swine-origin influenza A (H1N1) virus with epitopes in 2008-2009 conventional influenza vaccine

scientific article published on 4 August 2009

Immunoinformatic discovery of potential cross-reactive T cell epitopes in the measles genome

article

Immunoinformatic-drivenH. pylorivaccine design

article

Immunoinformatics Applied to Modifying and Improving Biological Therapeutics

article

Immunoinformatics: The Next Step in Vaccine Design

article

Immunome-derived Epitope-driven Vaccines (ID-EDV) Protect against Viral or Bacterial Challenge in Humanized Mice

Immunome-derived vaccines

scientific article published in June 2004

Immunomics: discovering new targets for vaccines and therapeutics

scientific article

In Vivo Validation of Predicted and Conserved T Cell Epitopes in a Swine Influenza Model.

scientific article

In silico predictions; in vivo veritas

scientific article published in June 1999

In silico-accelerated identification of conserved and immunogenic variola/vaccinia T-cell epitopes.

scientific article published on 24 June 2009

In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity

scientific article published on 02 September 2012

Innovation, urgency and acceptance at the 9th Vaccine Renaissance

scientific article published in December 2016

Integrated assessment of predicted MHC binding and cross-conservation with self reveals patterns of viral camouflage

scientific article

Introduction to the Compendium

Knowledge, attitudes, practices and willingness to vaccinate in preparation for the introduction of HPV vaccines in Bamako, Mali

scientific article

Knowledge/attitude/practices of HPV & cervical cancer, willingness to participate in vaccine trial in preparation for HIV & HPV vaccine trials in Mali.

scientific article published on 13 September 2012

Learning from the past, planning for the future--DOT for HIV infection.

scientific article published in July 2002

Legacy of light for women living with HIV in prison

scientific article published in The Lancet

Low immunogenicity predicted for emerging avian-origin H7N9: implication for influenza vaccine design.

scientific article

Making vaccines "on demand": a potential solution for emerging pathogens and biodefense?

scientific article

Mapping cross-clade HIV-1 vaccine epitopes using a bioinformatics approach

scientific article published in October 2003

Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ.

scientific article published on 22 March 2018

Modelling the immunogenicity of therapeutic proteins using T cell epitope mapping

scientific article published on 01 January 2003

Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes

scientific article published on 16 July 2013

Molecular epidemiology of HIV-1 infection in the Philippines, 1985 to 1997: transmission of subtypes B and E and potential emergence of subtypes C and F.

scientific article

MovingHelicobacter pylorivaccine development forward with bioinformatics and immunomics

article

Multi-step screening of neoantigens' HLA- and TCR-interfaces improves prediction of survival

scientific article published on 11 May 2021

Mycobacterium tuberculosis

scholarly article published 2009

New tools, new approaches and new ideas for vaccine development

article

New vaccines needed for pathogens infecting animals and humans: One Health

scientific article published on 28 June 2012

Novel function of complement C3d as an autologous helper T-cell target

scientific article published on 8 January 2008

Nucleophosmin leukaemic mutants contain C-terminus peptides that bind HLA class I molecules

scientific article published on 09 August 2007

Of [Hamsters] and men: a new perspective on host cell proteins.

scientific article published on September 2012

P15-07. Knowledge, attitudes, practices and willingness to participate in HIV vaccine trials among urban residents of Bamako, Mali, in West Africa, 2005–2009

article

Partial pathogen protection by tick-bite sensitization and epitope recognition in peptide-immunized HLA DR3 transgenic mice.

scientific article

Pediatric HIV infection due to maternal transmission: a solvable problem in a peri-urban setting in Bamako, Mali

scientific article published on 13 September 2012

Peptide-pulsed dendritic cells induce the hepatitis C viral epitope-specific responses of naïve human T cells

scientific article published on 8 April 2014

Place to be healthy: blueprint for a new free clinic for the medically uninsured of Rhode Island

scientific article published on 01 April 2008

Potential application of tregitopes as immunomodulating agents in multiple sclerosis

scientific article published on 15 September 2011

Preclinical development of HIvax: Human survivin highly immunogenic vaccines

scientific article published on July 2015

Prediction of immunogenicity for therapeutic proteins: state of the art.

scientific article published on May 2007

Prediction of immunogenicity: in silico paradigms, ex vivo and in vivo correlates

scientific article published on 19 September 2008

Prediction of well-conserved HIV-1 ligands using a matrix-based algorithm, EpiMatrix.

scientific article published in November 1998

Prevalence of HPV 16 and 18 and attitudes toward HPV vaccination trials in patients with cervical cancer in Mali

scientific article

Putting immunoinformatics to the test.

scientific article published in July 2006

Rapid Determination of HLA B*07 Ligands from the West Nile Virus NY99 Genome

scientific article (publication date: 2001)

Reducing risk, improving outcomes: bioengineering less immunogenic protein therapeutics

scientific article published on 06 March 2009

Regulatory T cell epitopes (Tregitopes) in IgG induce tolerance in vivo and lack immunogenicity per se.

scientific article

Report from the field: Fifth Vaccine Renaissance in Providence RI.

scientific article

Report from the field: Overview of the Sixth Annual Vaccine Renaissance Conference

scientific article published on 31 May 2013

Review ofBioinformatics for Vaccinologyby Darren R. Flower, Ph.D

SAT-133 Vida Sana Year 3: Improvements in Health Literacy and Risk Factors for Metabolic Syndrome in Participants in a Healthy Lifestyle Initiative at a Clinic for Low-Income Inner City Patients.

scientific article

Shedding light on correctional HIV care

scientific article published on 01 May 2000

Smarter vaccine design will circumvent regulatory T cell-mediated evasion in chronic HIV and HCV infection

scientific article published on 6 October 2014

Species neutral correlates of immunogenicity for vaccines and protein therapeutics: fact or science fiction

scientific article published on May 2010

T cell epitope engineering: an avian H7N9 influenza vaccine strategy for pandemic preparedness and response

scholarly article by Leonard Moise et al published 17 July 2018 in Human Vaccines & Immunotherapeutics

T cell epitope identification for bovine vaccines: an epitope mapping method for BoLA A-11.

scientific article

T cell epitope redundancy: cross-conservation of the TCR face between pathogens and self and its implications for vaccines and autoimmunity

scientific article

T cell epitope: friend or foe? Immunogenicity of biologics in context

scientific article published on 18 July 2009

T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation

scientific article published on 25 September 2013

T-cell epitope content comparison (EpiCC) of swine H1 influenza A virus hemagglutinin

scientific article published on 20 October 2017

Teaching tolerance: New approaches to enzyme replacement therapy for Pompe disease

scientific article published on October 2012

The Sir Mark Oliphant Conferences: international frontiers of science and technology

scientific article published on 01 July 2008

The measles campaign in West and Central Africa: remembering the future

scientific article

The need for compassionate care: HIV infection among incarcerated women

scientific article published on 01 June 1998

The role of glutamic or aspartic acid in position four of the epitope binding motif and thyrotropin receptor-extracellular domain epitope selection in Graves' disease

scientific article published on 14 April 2010

The two-faced T cell epitope: examining the host-microbe interface with JanusMatrix.

scientific article published on 12 April 2013

Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction

scientific article published on 06 November 2019

Thyrotropin receptor epitopes and their relation to histocompatibility leukocyte antigen-DR molecules in Graves' disease

scientific article published on 4 April 2006

Time for T? Immunoinformatics addresses vaccine design for neglected tropical and emerging infectious diseases

scientific article published on 5 September 2014

Time for T?: Thoughts about the 2009 novel H1N1 influenza outbreak and the role of T cell epitopes in the next generation of influenza vaccines

scientific article

Tools for Vaccine Design: Prediction and Validation of Highly Immunogenic and Conserved Class II Epitopes and Development of Epitope-Driven Vaccines

article

Tregitope peptides: the active pharmaceutical ingredient of IVIG?

scientific article published on 25 December 2013

Tregitope update: mechanism of action parallels IVIg

scientific article

Tregitope: Immunomodulation powerhouse

scientific article published on 22 October 2014

Two novel T cell epitope prediction algorithms based on MHC-binding motifs; comparison of predicted and published epitopes from Mycobacterium tuberculosis and HIV protein sequences

scientific article published in April 1995

Universal H1N1 influenza vaccine development: identification of consensus class II hemagglutinin and neuraminidase epitopes derived from strains circulating between 1980 and 2011.

scientific article

Use of bioinformatics to predict MHC ligands and T-cell epitopes: Application to epitope-driven vaccine design

Vaccination and Autoimmunity

scholarly article published 28 January 2004

Vaccine informatics

scientific article published on January 2010

Vaccine renaissance--from basic research to implementation

scientific article published on 01 October 2007

VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever

scientific article

VennVax, a DNA-prime, peptide-boost multi-T-cell epitope poxvirus vaccine, induces protective immunity against vaccinia infection by T cell response alone

scientific article

Vida Sana: a lifestyle intervention for uninsured, predominantly Spanish-speaking immigrants improves metabolic syndrome indicators

scientific article published in February 2015

Women incest survivors in prison. An open letter from a prison doctor to those who care for women living with HIV.

scientific article

iVAX: An integrated toolkit for the selection and optimization of antigens and the design of epitope-driven vaccines.

scientific article published on 9 July 2015