List of works - Melitta Schachner

Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system

scientific article published on April 1981

Neural cell adhesion molecules and myelin-associated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1.

scientific article published in September 1984

Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10

scientific journal article

Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

scientific article published on August 25, 1988

Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM

scientific article published in Nature

Immunocytochemical demonstration of vimentin in astrocytes and ependymal cells of developing and adult mouse nervous system.

scientific article published on August 1981

Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion

scientific article published on January 1, 1984

Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons

scientific article published in November 1992

Disruption of the mouse L1 gene leads to malformations of the nervous system

scientific article published on November 1, 1997

The J1 glycoprotein--a novel nervous system cell adhesion molecule of the L2/HNK-1 family

scientific article

L1 mono- and polyclonal antibodies modify cell migration in early postnatal mouse cerebellum

scientific article

Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons

scientific article

F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation

scientific journal article

Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth.

scientific article

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve

scientific article published on December 1986

Isolation of a neural chondroitin sulfate proteoglycan with neurite outgrowth promoting properties

scientific article

Glycans and neural cell interactions

scientific article published on March 2004

Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance

scientific article published on 01 August 2000

Differential inhibition of neurone-neurone, neurone-astrocyte and astrocyte-astrocyte adhesion by L1, L2 and N-CAM antibodies

scientific article

Extracellular matrix molecules and synaptic plasticity

scientific article

The dual role of the extracellular matrix in synaptic plasticity and homeostasis

scientific article published on 14 October 2010

The adhesion molecule on glia (AMOG) is a homologue of the beta subunit of the Na,K-ATPase

scientific article published in January 1990

The L2/HNK-1 carbohydrate of neural cell adhesion molecules is involved in cell interactions

scientific article published on January 1988

Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neuron-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction

scientific article published on October 1987

Axonal regrowth after spinal cord transection in adult zebrafish

scientific article published on 01 January 1997

Cosignaling of NCAM via lipid rafts and the FGF receptor is required for neuritogenesis

scientific article published on 29 April 2002

Activity-dependent formation and functions of chondroitin sulfate-rich extracellular matrix of perineuronal nets

scientific article

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and myelin-associated glycoprotein) in regenerating adult mouse sciatic nerve

scientific article

Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies

scientific article published on 01 November 1995

Postnatal development of perineuronal nets in wild-type mice and in a mutant deficient in tenascin-R

scientific journal article

J1-160 and J1-180 are oligodendrocyte-secreted nonpermissive substrates for cell adhesion

scientific article published on October 1989

Expression of several adhesive macromolecules (N-CAM, L1, J1, NILE, uvomorulin, laminin, fibronectin, and a heparan sulfate proteoglycan) in embryonic, adult, and denervated adult skeletal muscle

scientific article

Modification of extracellular matrix by enzymatic removal of chondroitin sulfate and by lack of tenascin-R differentially affects several forms of synaptic plasticity in the hippocampus

scientific journal article

Mice deficient in the polysialyltransferase ST8SiaIV/PST-1 allow discrimination of the roles of neural cell adhesion molecule protein and polysialic acid in neural development and synaptic plasticity.

scientific article published in July 2000

Lack of evidence that myelin-associated glycoprotein is a major inhibitor of axonal regeneration in the CNS.

scientific article published on December 1995

Enhanced expression of the developmentally regulated extracellular matrix molecule tenascin following adult brain injury

scientific article published on April 1, 1992

The F3/11 cell adhesion molecule mediates the repulsion of neurons by the extracellular matrix glycoprotein J1-160/180

scientific article published on January 1, 1993

Studies of adhesion molecules mediating interactions between cells of peripheral nervous system indicate a major role for L1 in mediating sensory neuron growth on Schwann cells in culture

scientific article published on July 1988

Potassium channel distribution, clustering, and function in remyelinating rat axons

scientific article published on 01 January 1998

J1/tenascin in substrate-bound and soluble form displays contrary effects on neurite outgrowth

scientific article published on June 1991

Glycans and the modulation of neural-recognition molecule function.

scientific article published on April 1995

Channel expression correlates with differentiation stage during the development of oligodendrocytes from their precursor cells in culture

scientific article published on 01 February 1989

Polysialylated neural cell adhesion molecule promotes remodeling and formation of hippocampal synapses.

scientific article published in October 2004

Immunohistological localization of the adhesion molecules L1, N-CAM, and MAG in the developing and adult optic nerve of mice

scientific article published in June 1989

Differential expression of transforming growth factor-beta 1, -beta 2, and -beta 3 by glioblastoma cells, astrocytes, and microglia

scientific article published on March 1, 1992

Tenascin-R is a functional modulator of sodium channel beta subunits

scientific article published on September 1999

Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junction protein connexin 32

scientific article published on 01 June 1997

Disruption of the gene for the myelin-associated glycoprotein improves axonal regrowth along myelin in C57BL/Wlds mice.

scientific article published in June 1996

High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule

scientific article

Crucial role for the myelin-associated glycoprotein in the maintenance of axon-myelin integrity

scientific article published on 01 March 1995

List of works by Melitta Schachner

Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system

Neural cell adhesion molecules and myelin-associated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1.

Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10

Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM

Immunocytochemical demonstration of vimentin in astrocytes and ependymal cells of developing and adult mouse nervous system.

Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion

Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons

Disruption of the mouse L1 gene leads to malformations of the nervous system

The J1 glycoprotein--a novel nervous system cell adhesion molecule of the L2/HNK-1 family

L1 mono- and polyclonal antibodies modify cell migration in early postnatal mouse cerebellum

Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons

F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation

Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth.

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve

Isolation of a neural chondroitin sulfate proteoglycan with neurite outgrowth promoting properties

Glycans and neural cell interactions

Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance

Differential inhibition of neurone-neurone, neurone-astrocyte and astrocyte-astrocyte adhesion by L1, L2 and N-CAM antibodies

Extracellular matrix molecules and synaptic plasticity

The dual role of the extracellular matrix in synaptic plasticity and homeostasis

The adhesion molecule on glia (AMOG) is a homologue of the beta subunit of the Na,K-ATPase

The L2/HNK-1 carbohydrate of neural cell adhesion molecules is involved in cell interactions

Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neuron-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction

Axonal regrowth after spinal cord transection in adult zebrafish

Cosignaling of NCAM via lipid rafts and the FGF receptor is required for neuritogenesis

Activity-dependent formation and functions of chondroitin sulfate-rich extracellular matrix of perineuronal nets

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and myelin-associated glycoprotein) in regenerating adult mouse sciatic nerve

Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies

Postnatal development of perineuronal nets in wild-type mice and in a mutant deficient in tenascin-R

J1-160 and J1-180 are oligodendrocyte-secreted nonpermissive substrates for cell adhesion

Expression of several adhesive macromolecules (N-CAM, L1, J1, NILE, uvomorulin, laminin, fibronectin, and a heparan sulfate proteoglycan) in embryonic, adult, and denervated adult skeletal muscle

Modification of extracellular matrix by enzymatic removal of chondroitin sulfate and by lack of tenascin-R differentially affects several forms of synaptic plasticity in the hippocampus

Mice deficient in the polysialyltransferase ST8SiaIV/PST-1 allow discrimination of the roles of neural cell adhesion molecule protein and polysialic acid in neural development and synaptic plasticity.

Lack of evidence that myelin-associated glycoprotein is a major inhibitor of axonal regeneration in the CNS.

Enhanced expression of the developmentally regulated extracellular matrix molecule tenascin following adult brain injury

The F3/11 cell adhesion molecule mediates the repulsion of neurons by the extracellular matrix glycoprotein J1-160/180

Studies of adhesion molecules mediating interactions between cells of peripheral nervous system indicate a major role for L1 in mediating sensory neuron growth on Schwann cells in culture

Potassium channel distribution, clustering, and function in remyelinating rat axons

J1/tenascin in substrate-bound and soluble form displays contrary effects on neurite outgrowth

Glycans and the modulation of neural-recognition molecule function.

Channel expression correlates with differentiation stage during the development of oligodendrocytes from their precursor cells in culture

Polysialylated neural cell adhesion molecule promotes remodeling and formation of hippocampal synapses.

Immunohistological localization of the adhesion molecules L1, N-CAM, and MAG in the developing and adult optic nerve of mice

Differential expression of transforming growth factor-beta 1, -beta 2, and -beta 3 by glioblastoma cells, astrocytes, and microglia

Tenascin-R is a functional modulator of sodium channel beta subunits

Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junction protein connexin 32

Disruption of the gene for the myelin-associated glycoprotein improves axonal regrowth along myelin in C57BL/Wlds mice.

High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule

Crucial role for the myelin-associated glycoprotein in the maintenance of axon-myelin integrity