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List of works by Alex Zhavoronkov

3D Molecular Representations Based on the Wave Transform for Convolutional Neural Networks

scientific article published on 23 February 2018

A review of the biomedical innovations for healthy longevity

scientific article

A role for G-CSF and GM-CSF in nonmyeloid cancers

scientific article

ARDD 2020: from aging mechanisms to interventions

scientific article published on 30 December 2020

Adversarial Threshold Neural Computer for Molecular de Novo Design

scientific article published on 23 March 2018

Aging Chart: a community resource for rapid exploratory pathway analysis of age-related processes

scientific article

Aging and drug discovery

scientific article published on 01 November 2018

Applications of Deep Learning in Biomedicine

scientific article published on 23 March 2016

Artificial Intelligence for Drug Discovery, Biomarker Development, and Generation of Novel Chemistry

article

Artificial intelligence for aging and longevity research: Recent advances and perspectives

scientific article published on 22 November 2018

Artificial intelligence, drug repurposing and peer review

scientific article published on 14 September 2020

Biomedical progress rates as new parameters for models of economic growth in developed countries

scientific article

Blood Biochemistry Analysis to Detect Smoking Status and Quantify Accelerated Aging in Smokers

scientific article published in Scientific Reports

COVIDomic: A multi-modal cloud-based platform for identification of risk factors associated with COVID-19 severity

scientific article published on 14 July 2021

Cancer megafunds with in silico and in vitro validation: accelerating cancer drug discovery via financial engineering without financial crisis

scientific article published on 3 June 2016

Classifying aging as a disease in the context of ICD-11.

scientific article published on 4 November 2015

Common pathway signature in lung and liver fibrosis

scientific article

Converging blockchain and next-generation artificial intelligence technologies to decentralize and accelerate biomedical research and healthcare ⬇️

scientific article published on 9 November 2017

DNA comet Giemsa staining for conventional bright-field microscopy

scientific article

Deep Aging Clocks: The Emergence of AI-Based Biomarkers of Aging and Longevity

scientific article published on 03 July 2019

Deep Learning Applications for Predicting Pharmacological Properties of Drugs and Drug Repurposing Using Transcriptomic Data

scientific article (publication date: 5 July 2016)

Deep biomarkers of human aging: Application of deep neural networks to biomarker development

scientific article

Deep learning enables rapid identification of potent DDR1 kinase inhibitors

scientific article published on 02 September 2019

Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic

scientific article

Differential expression of alternatively spliced transcripts related to energy metabolism in colorectal cancer.

scientific article

Editorial: Should We Treat Aging as a Disease? Academic, Pharmaceutical, Healthcare Policy, and Pension Fund Perspectives

scientific article published on 16 February 2016

Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells

scientific article

Effects of N-acetyl-L-cysteine on lifespan, locomotor activity and stress-resistance of 3 species with different lifespans

Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster

article

Entangled Conditional Adversarial Autoencoder for de Novo Drug Discovery

scientific article published on 19 September 2018

Exhaustive data mining comparison of the effects of low doses of ionizing radiation, formaldehyde and dioxins

scientific article published on 19 December 2014

From personalized medicine to personalized science: uniting science and medicine for patient-driven, goal-oriented research

scientific article published in October 2013

Fucoxanthin increases lifespan of Drosophila melanogaster and Caenorhabditis elegans

scientific article published on 17 August 2015

GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma

scientific article published on 18 August 2020

Genetics and epigenetics of aging and longevity

scientific article

In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state.

scientific article published on 24 September 2016

In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development.

scientific article

In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia

scientific article published on 22 May 2017

Influence of non-steroidal anti-inflammatory drugs on Drosophila melanogaster longevity

scientific article

Interactome analysis of myeloid-derived suppressor cells in murine models of colon and breast cancer

scientific article

Interview with Alex Zhavoronkov, PhD.

scientific article published in August 2015

Large-scale profiling of signalling pathways reveals an asthma specific signature in bronchial smooth muscle cells

scientific article published on 05 February 2016

Latest advances in aging research and drug discovery

scientific article published on 21 November 2019

Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes

scientific article

Longevity expectations in the pension fund, insurance, and employee benefits industries

scientific article

Machine Learning on Human Muscle Transcriptomic Data for Biomarker Discovery and Tissue-Specific Drug Target Identification

scholarly article by Polina Mamoshina et al published 2018 in Frontiers in Genetics

Medicinal Chemists versus Machines Challenge: What Will It Take to Adopt and Advance Artificial Intelligence for Drug Discovery?

scientific article published on 29 May 2020

Meeting Report: Aging Research and Drug Discovery

scientific article published on 28 January 2022

Methods for structuring scientific knowledge from many areas related to aging research

scientific article published in 2011

Models of Innate Neural Attractors and Their Applications for Neural Information Processing

scientific article published on January 2015

Molecular pathway activation features linked with transition from normal skin to primary and metastatic melanomas in human

scientific article published on 26 November 2015

Molecular pathway activation features of pediatric acute myeloid leukemia (AML) and acute lymphoblast leukemia (ALL) cells

scientific article

Overexpression of CBS and CSE genes affects lifespan, stress resistance and locomotor activity in Drosophila melanogaster.

article

Pathway activation profiling reveals new insights into age-related macular degeneration and provides avenues for therapeutic interventions

scientific article published on December 2014

PhotoAgeClock: deep learning algorithms for development of non-invasive visual biomarkers of aging

article

Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases

scientific article

Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma

scientific article published on 26 May 2016

Quantifying signaling pathway activation to monitor the quality of induced pluripotent stem cells

scientific article published on 22 August 2015

Reinforced Adversarial Neural Computer for de Novo Molecular Design

scientific article published on 12 June 2018

Replicative and radiation-induced aging: a comparison of gene expression profiles

article

Reply to 'Assessing the impact of generative AI on medicinal chemistry'

scientific article published on 01 February 2020

Screening and personalizing nootropic drugs and cognitive modulator regimens in silico

scientific article published on 6 February 2015

Signaling pathway cloud regulation for in silico screening and ranking of the potential geroprotective drugs

scientific article published on 3 March 2014

TNIK’s emerging role in cancer, metabolism, and age-related diseases

scientific article published in 2024

The Advent of Human Life Data Economics

scientific article published on 27 June 2019

The Evaluation of Geroprotective Effects of Selected Flavonoids in Drosophila melanogaster and Caenorhabditis elegans.

scientific article published on 7 December 2017

The Neuronal Overexpression of in Induces Life Extension With Longevity-Associated Transcriptomic Changes in the Thorax

Towards natural mimetics of metformin and rapamycin

scientific article published on 15 November 2017

Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity

scientific article published on 24 June 2019

Use of deep neural network ensembles to identify embryonic-fetal transition markers: repression of COX7A1 in embryonic and cancer cells

scientific article published on 28 December 2017

Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization.

scientific article published on 12 February 2018

Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology?

scientific article published on 03 March 2020

druGAN: An Advanced Generative Adversarial Autoencoder Model for de Novo Generation of New Molecules with Desired Molecular Properties in Silico

scientific article published on 13 July 2017

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