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List of works by David R. Liu

A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing

scientific article published on 08 July 2020

Addendum: High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases

scientific article published on 02 July 2019

Adenine base editing in an adult mouse model of tyrosinaemia

scientific article published on 25 February 2019

An anionic human protein mediates cationic liposome delivery of genome editing proteins into mammalian cells

scientific article published on 02 July 2019

Analysis and minimization of cellular RNA editing by DNA adenine base editors

scientific article published on 08 May 2019

Author Correction: Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors

scientific article published on 01 July 2019

Author Correction: Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity

scientific article published on 20 May 2020

Base editing of haematopoietic stem cells rescues sickle cell disease in mice

scientific article published on 02 June 2021

Base editing rescue of spinal muscular atrophy in cells and in mice

scientific article published on 30 March 2023

Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors

scientific article published on 20 May 2019

Continuous evolution of SpCas9 variants compatible with non-G PAMs

scientific article published on 10 February 2020

Continuous evolution of base editors with expanded target compatibility and improved activity

scientific article published on 22 July 2019

Continuous evolution of compact protein degradation tags regulated by selective molecular glues

scientific article published on 14 March 2024

Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses

scientific article published on 14 January 2020

DNA capture by a CRISPR-Cas9-guided adenine base editor

scientific article published on 01 July 2020

Designing and executing prime editing experiments in mammalian cells

scientific article published in 2022

Development of hRad51-Cas9 nickase fusions that mediate HDR without double-stranded breaks

article

Discovery of a Covalent Kinase Inhibitor from a DNA-Encoded Small-Molecule Library × Protein Library Selection

scientific article

Editing the Genome Without Double-Stranded DNA Breaks.

scientific article published on 28 September 2017

Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors

scientific article published in 2022

Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors

scientific article published on 10 February 2020

Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors

scientific article published on 22 June 2020

High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases

scientific article published on 26 April 2019

High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells

scientific article published on 14 January 2020

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.

scientific article published on 30 August 2017

In vivo base editing by a single intravenous vector injection for treatment of hemoglobinopathies

scientific article published in 2022

In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice

scientific article published on 06 January 2021

In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness

scientific article published on 01 June 2020

Phage-Assisted Evolution of Bacillus methanolicus Methanol Dehydrogenase 2

scientific article published on 20 March 2019

Phage-assisted continuous and non-continuous evolution

scientific article published on 16 November 2020

Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity

scientific article published on 16 March 2020

Prime genome editing in rice and wheat

scientific article published on 16 March 2020

Programmable m6A modification of cellular RNAs with a Cas13-directed methyltransferase

scientific article published on 29 June 2020

Publisher Correction: Continuous evolution of base editors with expanded target compatibility and improved activity

scientific article published on 01 September 2019

Publisher Correction: Efficient in vivo base editing via single adenoassociated viruses with size-optimized genomes encoding compact adenine base editors

correction of a scholarly article

Publisher Correction: Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing

scientific article published on 29 October 2020

Publisher Correction: Side chain determinants of biopolymer function during selection and replication

scientific article published on 01 May 2019

Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing

scientific article published on 19 October 2020

Rewritable multi-event analog recording in bacterial and mammalian cells.

scientific article published on 15 February 2018

Side chain determinants of biopolymer function during selection and replication

scientific article published on 11 February 2019

Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme

scientific article published on 13 May 2019

The developing toolkit of continuous directed evolution

scientific article published on 22 May 2020

Towards DNA-Based Programmable Matter

technical report published in 2012

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