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List of works by Clemens van Blitterswijk

'Smart' biomaterials and osteoinductivity

scientific article published on 01 April 2011

3D fiber-deposited scaffolds for tissue engineering: influence of pores geometry and architecture on dynamic mechanical properties

scientific article published in August 2005

3D microenvironment as essential element for osteoinduction by biomaterials

scientific article published in June 2005

3D-Fiber Deposition for Tissue Engineering and Organ Printing Applications

scholarly article published 2010

A Fast Process for Imprinting Micro and Nano Patterns on Electrospun Fiber Meshes at Physiological Temperatures

scholarly article by Anandkumar Nandakumar et al published 27 February 2013 in Small

A New Microengineered Platform for 4D Tracking of Single Cells in a Stem-Cell-Based In Vitro Morphogenesis Model

scientific article published on 29 April 2020

A Wnt/β-catenin negative feedback loop inhibits interleukin-1-induced matrix metalloproteinase expression in human articular chondrocytes

scientific article

A biocomposite of collagen nanofibers and nanohydroxyapatite for bone regeneration

scientific article published on 13 June 2014

A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells

scientific article published on 29 January 2012

A clinical feasibility study to evaluate the safety and efficacy of PEOT/PBT implants for human donor site filling during mosaicplasty

scientific article published on 6 December 2011

A combinatorial approach towards the design of nanofibrous scaffolds for chondrogenesis

scientific article

A comparison of bone formation in biphasic calcium phosphate (BCP) and hydroxyapatite (HA) implanted in muscle and bone of dogs at different time periods

scientific article published on 01 July 2006

A comparison of the osteoinductive potential of two calcium phosphate ceramics implanted intramuscularly in goats

scientific article published on 01 December 2002

A controlled release system for proteins based on poly(ether ester) block-copolymers: polymer network characterization

scientific article published on 01 December 1999

A cultured living bone equivalent enhances bone formation when compared to a cell seeding approach

scientific article published in June 2002

A dual flow bioreactor with controlled mechanical stimulation for cartilage tissue engineering

scientific article published on 15 April 2013

A link between the accumulation of DNA damage and loss of multi-potency of human mesenchymal stromal cells

scientific article published on December 2010

A mesenchymal stromal cell gene signature for donor age

scientific article

A modular versatile chip carrier for high-throughput screening of cell–biomaterial interactions

scientific article published on January 6, 2013

A new biodegradable matrix as part of a cell seeded skin substitute for the treatment of deep skin defects: a physico-chemical characterisation

scientific article published in January 1993

A new in vivo screening model for posterior spinal bone formation: comparison of ten calcium phosphate ceramic material treatments.

scientific article published on 18 August 2005

A newly developed chemically crosslinked dextran-poly(ethylene glycol) hydrogel for cartilage tissue engineering

scientific article

A perfusion bioreactor system capable of producing clinically relevant volumes of tissue-engineered bone: in vivo bone formation showing proof of concept

scientific article published on 25 August 2005

A rapid and efficient method for expansion of human mesenchymal stem cells

scientific article published in January 2007

A small molecule approach to engineering vascularized tissue.

scientific article

A study on the grafting reaction of isocyanates with hydroxyapatite particles

scientific article published on 01 June 1998

A supramolecular host-guest carrier system for growth factors employing V(H)H fragments.

scientific article published on 29 August 2014

Acute Otitis Media: An Animal Experimental Study

scientific article published on 01 September 1984

Adhesion and proliferation of cells and bacteria on microchip with different surfaces microstructures

scientific article published on 18 December 2015

Adhesion-mediated signal transduction in human articular chondrocytes: the influence of biomaterial chemistry and tenascin-C.

scientific article published in December 2004

Advanced biomaterials for skeletal tissue regeneration: Instructive and smart functions

Amphiphilic beads as depots for sustained drug release integrated into fibrillar scaffolds

scientific article

Amphiphilic poly(ether ester amide) multiblock copolymers as biodegradable matrices for the controlled release of proteins

scientific article published on 01 October 2000

An Approach to In Vitro Manufacturing of Hypertrophic Cartilage Matrix for Bone Repair

scientific article published on 20 April 2017

An algorithm-based topographical biomaterials library to instruct cell fate

scientific article

An antibody based approach for multi-coloring osteogenic and chondrogenic proteins in tissue engineered constructs

An open source image processing method to quantitatively assess tissue growth after non-invasive magnetic resonance imaging in human bone marrow stromal cell seeded 3D polymeric scaffolds

scientific article

Analysis of ectopic and orthotopic bone formation in cell-based tissue-engineered constructs in goats

scientific article published on 19 December 2006

Analysis of high-throughput screening reveals the effect of surface topographies on cellular morphology.

scientific article published on 30 December 2014

Anatomical 3D fiber-deposited scaffolds for tissue engineering: designing a neotrachea

scientific article published in October 2007

Application and Limitations of Chloromethyl-benzamidodialkylcarbocyanine for Tracing Cells Used in Bone Tissue Engineering

scientific article published on 01 February 2003

Application of porous PEO/PBT copolymers for bone replacement

scientific article published on 01 March 1996

Assessment of Cell–Material Interactions in Three Dimensions through Dispersed Coaggregation of Microsized Biomaterials into Tissue Spheroids

scientific article published in 2022

Assessment of bioactivity for orthopedic coatings in a gap-healing model

scientific article published on 01 August 1997

Bilayered biodegradable poly(ethylene glycol)/poly(butylene terephthalate) copolymer (Polyactive) as substrate for human fibroblasts and keratinocytes.

scientific article published on December 1999

Biocompatibility of a polyether urethane, polypropylene oxide, and a polyether polyester copolymer. A qualitative and quantitative study of three alloplastic tympanic membrane materials in the rat middle ear

scientific article published on 01 April 1990

Bioinformatics-based selection of a model cell type for in vitro biomaterial testing.

scientific article published on 28 April 2013

Biological and Tribological Assessment of Poly(Ethylene Oxide Terephthalate)/Poly(Butylene Terephthalate), Polycaprolactone, and Poly (L\DL) Lactic Acid Plotted Scaffolds for Skeletal Tissue Regeneration

scientific article published on 25 November 2015

Biological performance in goats of a porous titanium alloy-biphasic calcium phosphate composite

scientific article published on 5 July 2007

Biological performance of uncoated and octacalcium phosphate-coated Ti6Al4V.

scientific article published in January 2005

Bioluminescent imaging: emerging technology for non-invasive imaging of bone tissue engineering

scientific article

Biomimetic calcium phosphate coatings on Ti6AI4V: a crystal growth study of octacalcium phosphate and inhibition by Mg2+ and HCO3-

Biomimetic calcium phosphate coatings on recombinant spider silk fibres

Biomimetic coatings on titanium: a crystal growth study of octacalcium phosphate

scientific article published on 01 June 2001

Biomimetic coprecipitation of calcium phosphate and bovine serum albumin on titanium alloy

scientific article published in December 2001

Bioprinting Via a Dual-Gel Bioink Based on Poly(Vinyl Alcohol) and Solubilized Extracellular Matrix towards Cartilage Engineering

scientific article published in 2021

Bioreactions at the tissue/ hydroxyapatite interface

scientific article published on 01 July 1985

Blastocyst-like structures generated solely from stem cells

scientific article published in Nature

Bone Tissue-Engineered Implants Using Human Bone Marrow Stromal Cells: Effect of Culture Conditions and Donor Age

article

Bone formation by mesenchymal progenitor cells cultured on dense and microporous hydroxyapatite particles

scientific article published in December 2003

Bone induction by porous glass ceramic made from Bioglass� (45S5)

scientific article published on 01 May 2001

Bone ingrowth in porous titanium implants produced by 3D fiber deposition

scientific article published on 23 March 2007

Bone regeneration: molecular and cellular interactions with calcium phosphate ceramics

scientific article

Bone tissue engineering for spine fusion: an experimental study on ectopic and orthotopic implants in rats.

scientific article published in January 2004

Bone tissue engineering in a critical size defect compared to ectopic implantations in the goat

scientific article published in May 2004

Bone tissue engineering on amorphous carbonated apatite and crystalline octacalcium phosphate-coated titanium discs

scientific article published in September 2005

Bone-bonding behaviour of poly(ethylene oxide)-polybutylene terephthalate copolymer coatings and bulk implants: a comparative study

scientific article published on 01 May 1995

Boosting angiogenesis and functional vascularization in injectable dextran-hyaluronic acid hydrogels by endothelial-like mesenchymal stromal cells

scientific article published on 12 November 2013

Building Complex Life Through Self-Organization

scientific article published on 20 September 2019

Calcium Phosphate Coated Electrospun Fiber Matrices as Scaffolds for Bone Tissue Engineering

scientific article published on 01 May 2010

Calcium phosphate interactions with titanium oxide and alumina substrates: an XPS study

scientific article published in May 2003

Calcium phosphates and silicon: exploring methods of incorporation

article published in 2017

Cancellous bone from porous Ti6Al4V by multiple coating technique

scientific article published in February 2006

Cartilage tissue engineering: controversy in the effect of oxygen

scientific article published on January 2003

Cationic polymers and their therapeutic potential

scientific article published on 10 August 2012

Cell based bone tissue engineering in jaw defects

scientific article

Cell culture dimensionality influences mesenchymal stem cell fate through cadherin-2 and cadherin-11

scientific article published on 21 May 2020

Cell sources for articular cartilage repair strategies: shifting from monocultures to cocultures.

scientific article published on 05 September 2012

Cell-based bone tissue engineering

scientific article

Cell-instructive high-resolution micropatterned polylactic acid surfaces

scientific article

Cells responding to surface structure of calcium phosphate ceramics for bone regeneration

scientific article published on 8 February 2017

Cellular reaction on the intraperitoneal injection of four types of polylactide particulates

scientific article published on 01 January 1992

Chitosan scaffolds containing hyaluronic acid for cartilage tissue engineering

scientific article published on 25 April 2011

Chitosan/Poly(ɛ-caprolactone) blend scaffolds for cartilage repair

scientific article published on 27 October 2010

Chondrocytes Cocultured with Stromal Vascular Fraction of Adipose Tissue Present More Intense Chondrogenic Characteristics Than with Adipose Stem Cells

scientific article published on 6 January 2016

Chondrogenesis in injectable enzymatically crosslinked heparin/dextran hydrogels

scientific article published on 01 February 2011

Clinical application of human mesenchymal stromal cells for bone tissue engineering

scientific article

Closer to Nature-Bio-inspired Patterns by Transforming Latent Lithographic Images

scientific article published on 21 September 2011

Co-culture in cartilage tissue engineering

scientific article published on May 2007

Coculturing Human Islets with Proangiogenic Support Cells to Improve Islet Revascularization at the Subcutaneous Transplantation Site.

scientific article published on 27 January 2016

Collagen modules forin situdelivery of mesenchymal stromal cell-derived endothelial cells for improved angiogenesis

scientific article published on April 17, 2013

Combinatorial incorporation of fluoride and cobalt ions into calcium phosphates to stimulate osteogenesis and angiogenesis

scientific article published on 29 February 2016

Combining technologies to create bioactive hybrid scaffolds for bone tissue engineering

scientific article published on January 2013

Comparative in vivo study of six hydroxyapatite-based bone graft substitutes

scientific article published in October 2008

Comparison of two carbonated apatite ceramics in vivo

scientific article published on 26 November 2009

Composite biomaterials with chemical bonding between hydroxyapatite filler particles and PEG/PBT copolymer matrix

scientific article published on 01 June 1998

Control of protein delivery from amphiphilic poly(ether ester) multiblock copolymers by varying their water content using emulsification techniques

scientific article published on 01 May 2000

Controlled aggregation of primary human pancreatic islet cells leads to glucose-responsive pseudoislets comparable to native islets

scientific article

Converge and regenerate

Corrigendum to "Tailoring surface nanoroughness of electrospun scaffolds for skeletal tissue engineering" Acta Biomater. 59 (2017) 82-93.

scientific article published on 6 February 2018

Covalent Binding of Bone Morphogenetic Protein-2 and Transforming Growth Factor-β3 to 3D Plotted Scaffolds for Osteochondral Tissue Regeneration

scientific article published on 2 September 2017

Creeping Proteins in Microporous Structures: Polymer Brush-Assisted Fabrication of 3D Gradients for Tissue Engineering

scientific article published on 13 February 2015

Critical Steps toward a tissue-engineered cartilage implant using embryonic stem cells

scientific article

Critical factors in the design of growth factor releasing scaffolds for cartilage tissue engineering

scientific article published on 01 May 2008

Cross-species comparison of ectopic bone formation in biphasic calcium phosphate (BCP) and hydroxyapatite (HA) scaffolds

scientific article published in June 2006

Darcian permeability constant as indicator for shear stresses in regular scaffold systems for tissue engineering

scientific article published on 10 April 2009

Decreased consumption of Ca and P during in vitro biomineralization and biologically induced deposition of Ni and Cr in presence of stainless steel corrosion products

scientific article

Degradative behaviour of polymeric matrices in (sub)dermal and muscle tissue of the rat: a quantitative study

scientific article published on 01 June 1994

Design of biphasic polymeric 3-dimensional fiber deposited scaffolds for cartilage tissue engineering applications

scientific article published in February 2007

Design of porous scaffolds for cartilage tissue engineering using a three-dimensional fiber-deposition technique.

scientific article published in August 2004

Designed Surface Topographies Control ICAM-1 Expression in Tonsil-Derived Human Stromal Cells

scientific article published on 28 June 2018

Development and analysis of multi-layer scaffolds for tissue engineering.

scientific article

Development and evaluation of in vivo tissue engineered blood vessels in a porcine model

scientific article published on 19 October 2015

Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties.

scientific article

Development of a shear stress-free microfluidic gradient generator capable of quantitatively analyzing single-cell morphology

scientific article published on 7 September 2017

Development of multilayer constructs for tissue engineering

scientific article published on 12 April 2012

Differential bone-forming capacity of osteogenic cells from either embryonic stem cells or bone marrow-derived mesenchymal stem cells

scientific article

Differential cell viability of chondrocytes and progenitor cells in tissue-engineered constructs following implantation into osteochondral defects

scientific article published in June 2006

Differentiation of Mesenchymal Stem Cells under Hypoxia and Normoxia: Lipid Profiles Revealed by Time-of-Flight Secondary Ion Mass Spectrometry and Multivariate Analysis

article

Direct Writing Electrospinning of Scaffolds with Multidimensional Fiber Architecture for Hierarchical Tissue Engineering

scientific article published on 18 October 2017

Directed Assembly and Development of Material-Free Tissues with Complex Architectures.

scientific article published on 22 March 2016

Distinct Effect of TCF4 on the NFκB Pathway in Human Primary Chondrocytes and the C20/A4 Chondrocyte Cell Line

scientific article published on July 2014

Distribution and Viability of Fetal and Adult Human Bone Marrow Stromal Cells in a Biaxial Rotating Vessel Bioreactor after Seeding on Polymeric 3D Additive Manufactured Scaffolds

scientific article

Diverse effects of cyclic AMP variants on osteogenic and adipogenic differentiation of human mesenchymal stromal cells.

scientific article published on 2 July 2012

Donor variation and loss of multipotency during in vitro expansion of human mesenchymal stem cells for bone tissue engineering

scientific article published in August 2007

Dual release of proteins from porous polymeric scaffolds

scientific article published on 7 February 2006

Dynamic mechanical properties of 3D fiber-deposited PEOT/PBT scaffolds: an experimental and numerical analysis.

scientific article published in September 2006

Ectopic bone formation by aggregated mesenchymal stem cells from bone marrow and adipose tissue: A comparative study.

scientific article

Editorial

Effect of antioxidant supplementation on the total yield, oxidative stress levels, and multipotency of bone marrow-derived human mesenchymal stromal cells

scientific article published on 5 January 2013

Effect of chordin-like 1 on MC3T3-E1 and human mesenchymal stem cells

scientific article

Effect of fibroblasts on epidermal regeneration

scientific article published in August 2002

Effect of implantation site on phagocyte/polymer interaction and fibrous capsule formation

scientific article published on 01 January 1988

Effect of stratified culture compared to confluent culture in monolayer on proliferation and differentiation of human articular chondrocytes

scientific article published in September 2006

Effect of vitamin A on the growth and differentiation of rat external auditory canal epithelium in organ culture

article

Effects of AISI 316L corrosion products in in vitro bone formation

scientific article published on 01 June 1998

Effects of Wnt signaling on proliferation and differentiation of human mesenchymal stem cells

scientific article published in March 2004

Effects of scaffold composition and architecture on human nasal chondrocyte redifferentiation and cartilaginous matrix deposition

scientific article published in May 2005

Effects of the architecture of tissue engineering scaffolds on cell seeding and culturing.

scientific article published on 16 June 2010

Electrolytic deposition of lithium into calcium phosphate coatings

scientific article published on 19 September 2008

Elucidating the individual effects of calcium and phosphate ions on hMSCs by using composite materials

article

Endochondral bone tissue engineering using embryonic stem cells

scholarly article

Endogenous collagen influences differentiation of human multipotent mesenchymal stromal cells

scientific article published in May 2010

Endothelial cells assemble into a 3-dimensional prevascular network in a bone tissue engineering construct

scientific article published in September 2006

Endothelial differentiation of mesenchymal stromal cells

scientific article

Engineered micro-objects as scaffolding elements in cellular building blocks for bottom-up tissue engineering approaches

scientific article published on 7 January 2014

Engineering New Bone via a Minimally Invasive Route Using Human Bone Marrow-Derived Stromal Cell Aggregates, Microceramic Particles, and Human Platelet-Rich Plasma Gel

scientific article published on 10 October 2012

Engineering of a dermal equivalent: seeding and culturing fibroblasts in PEGT/PBT copolymer scaffolds

scientific article published in October 2003

Engineering vascularized skeletal muscle tissue

scientific article

Enhancement of synthesis of extracellular matrix proteins on retinoic acid loaded electrospun scaffolds

scientific article published on 20 September 2018

Enzymatically crosslinked dextran-tyramine hydrogels as injectable scaffolds for cartilage tissue engineering

scientific article published in August 2010

Enzymatically-crosslinked injectable hydrogels based on biomimetic dextran-hyaluronic acid conjugates for cartilage tissue engineering

scientific article published on 8 February 2010

Enzyme-catalyzed crosslinkable hydrogels: emerging strategies for tissue engineering

scientific article

Epithelial reactions to hydroxyapatite. An in vivo and in vitro study

scientific article published in March 1986

Evaluating 3D bone tissue engineered constructs with different seeding densities using the alamarBlue assay and the effect on in vivo bone formation

scientific article published in December 2002

Evaluation of Photocrosslinked Lutrol Hydrogel for Tissue Printing Applications

scientific article published on 15 May 2009

Evaluation of chondrogenesis within PEGT: PBT scaffolds with high PEG content

scientific article published in October 2006

Evaluation of copolymers of polyethylene oxide and polybutylene terephthalate (polyactive): mechanical behaviour

scientific article published on 01 July 1998

Evaluation of polylactide monomers in an in vitro biocompatibility assay

scientific article published on 01 March 1994

Expansion of bovine chondrocytes on microcarriers enhances redifferentiation

scientific article published in October 2003

Expansion of human nasal chondrocytes on macroporous microcarriers enhances redifferentiation

scientific article

Exploring the Material-Induced Transcriptional Landscape of Osteoblasts on Bone Graft Materials

scientific article published on 5 June 2015

Extracellular matrix and tissue engineering applications

article

Fabrication of bioactive composite scaffolds by electrospinning for bone regeneration

scientific article published on November 2010

Fabrication of cell container arrays with overlaid surface topographies

scientific article

Fabrication, characterization and cellular compatibility of poly(hydroxy alkanoate) composite nanofibrous scaffolds for nerve tissue engineering

scientific article

Factors having influence on the rheological properties of Ti6A14V slurry

scientific article published in September 2004

Fiber diameter and texture of electrospun PEOT/PBT scaffolds influence human mesenchymal stem cell proliferation and morphology, and the release of incorporated compounds

scientific article published on 9 June 2006

Fibroblast growth factor-1 is a mesenchymal stromal cell-secreted factor stimulating proliferation of osteoarthritic chondrocytes in co-culture

scientific article published on 29 May 2013

Flexible Yttrium-Stabilized Zirconia Nanofibers Offer Bioactive Cues for Osteogenic Differentiation of Human Mesenchymal Stromal Cells.

scientific article

Flexible fluidic microchips based on thermoformed and locally modified thin polymer films.

scientific article published on 24 July 2008

Forskolin Enhances In Vivo Bone Formation by Human Mesenchymal Stromal Cells

scientific article published on 03 February 2012

From fiber curls to mesh waves: a platform for the fabrication of hierarchically structured nanofibers mimicking natural tissue formation

scientific article published on 01 August 2019

GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors.

scientific article published on 19 September 2013

Gene expression profiling of dedifferentiated human articular chondrocytes in monolayer culture

scientific article published on 30 January 2013

Gene expressions of Collagen type I, ALP and BMP-4 in osteo-inductive BCP implants show similar pattern to that of natural healing bones

article

Genetic marking with the DeltaLNGFR-gene for tracing goat cells in bone tissue engineering

scientific article published in July 2004

Geometric constraints of endothelial cell migration on electrospun fibres.

scientific article published on 23 April 2018

Goat Bone Tissue Engineering: Comparing an Intramuscular with a Posterolateral Lumbar Spine Location

scientific article published on 01 February 2010

Gradients in pore size enhance the osteogenic differentiation of human mesenchymal stromal cells in three-dimensional scaffolds

scientific article published on 10 March 2016

Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis

scientific article published on 01 October 2012

Grow with the Flow: When Morphogenesis Meets Microfluidics

scientific article published on 14 February 2019

Heterogeneity of concanavalin A binding by mouse peritoneal macrophages

scientific article published on 01 January 1982

High content imaging in the screening of biomaterial-induced MSC behavior.

scientific article published on 23 November 2012

High-Throughput Screening Assay for the Identification of Compounds Enhancing Collagenous Extracellular Matrix Production by ATDC5 Cells.

scientific article published on 8 April 2015

High-throughput assay for the identification of compounds regulating osteogenic differentiation of human mesenchymal stromal cells

scientific article

High-throughput screening approaches and combinatorial development of biomaterials using microfluidics

scientific article published on 08 September 2015

Human mesenchymal stromal cells response to biomimetic octacalcium phosphate containing strontium

scientific article published on 9 April 2016

Human tissue-engineered bone produced in clinically relevant amounts using a semi-automated perfusion bioreactor system: a preliminary study

scientific article published in January 2010

Hybrid Polyester-Hydrogel Electrospun Scaffolds for Tissue Engineering Applications

scientific article published on 25 September 2019

Hypoxia inhibits hypertrophic differentiation and endochondral ossification in explanted tibiae

scientific article

Improved enzymatic isolation of fibroblasts for the creation of autologous skin substitutes

scientific article published in September 2004

In Situ Covalent Reinforcement of a Benzene‐1,3,5‐Tricarboxamide Supramolecular Polymer Enables Biomimetic, Tough, and Fibrous Hydrogels and Bioinks

scientific article published in 2023

In vitro and in vivo bioactivity assessment of a polylactic acid/hydroxyapatite composite for bone regeneration

scientific article published on 17 January 2014

In vitro and in vivo bioluminescent imaging of hypoxia in tissue-engineered grafts

scientific article published in June 2010

In vitro biocompatibility of EPM and EPDM rubbers

scientific article published on 01 January 1997

In vivo bone formation by human bone marrow cells: effect of osteogenic culture supplements and cell densities

article

In vivo screening of extracellular matrix components produced under multiple experimental conditions implanted in one animal

scientific article published on 01 June 2013

In vivoevaluation of highly macroporous ceramic scaffolds for bone tissue engineering

scientific article published on 01 May 2010

Incorporation of bovine serum albumin in calcium phosphate coating on titanium

scientific article published on 01 August 1999

Increased cell seeding efficiency in bioplotted three-dimensional PEOT/PBT scaffolds

scientific article published on 8 November 2013

Inflammatory response and bone healing capacity of two porous calcium phosphate ceramics in critical size cortical bone defects

scientific article published on 12 June 2013

Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation

scientific article

Influence of ionic strength and carbonate on the Ca-P coating formation from SBFx5 solution

scientific article

Influence of octacalcium phosphate coating on osteoinductive properties of biomaterials

scientific article

Influencing chondrogenic differentiation of human mesenchymal stromal cells in scaffolds displaying a structural gradient in pore size.

scientific article published on 8 March 2016

Inhibition of histone acetylation as a tool in bone tissue engineering

scientific article published in October 2006

Initial bone matrix formation at the hydroxyapatite interfacein vivo

scientific article published on 01 January 1995

Injectable chitosan-based hydrogels for cartilage tissue engineering.

scientific article published on 26 January 2009

Insulin-Like Growth Factor-I Enhances Proliferation and Differentiation of Human Mesenchymal Stromal Cells In Vitro

scientific article published on 27 April 2013

Integrating novel technologies to fabricate smart scaffolds.

scientific article published on January 2008

Integration of hollow fiber membranes improves nutrient supply in three-dimensional tissue constructs.

scientific article published on 14 June 2011

Intra-scaffold continuous medium flow combines chondrocyte seeding and culture systems for tissue engineered trachea construction

scientific article published on 12 June 2008

Intracellular degradation of microspheres based on cross-linked dextran hydrogels or amphiphilic block copolymers: a comparative raman microscopy study

scientific article

Label-free Raman monitoring of extracellular matrix formation in three-dimensional polymeric scaffolds

scientific article published on 03 July 2013

Label-free detection of insulin and glucagon within human islets of Langerhans using Raman spectroscopy

scientific article

Layer-by-layer tissue microfabrication supports cell proliferation in vitro and in vivo

scientific article

Linking the Transcriptional Landscape of Bone Induction to Biomaterial Design Parameters.

scientific article published on 19 December 2016

Low oxygen tension stimulates the redifferentiation of dedifferentiated adult human nasal chondrocytes

scientific article published in April 2004

Macropore tissue ingrowth: a quantitative and qualitative study on hydroxyapatite ceramic

scientific article published in March 1986

Materiomics: an -omics approach to biomaterials research

scientific article

Mesenchymal stromal cell-derived extracellular matrix influences gene expression of chondrocytes

scientific article published on 27 February 2013

Mesenchymal stromal/stem cell-or chondrocyte-seeded microcarriers as building blocks for cartilage tissue engineering

scientific article published on 28 April 2014

Mesoporous Silica-Coated Gold Nanoparticles for Multimodal Imaging and Reactive Oxygen Species Sensing of Stem Cells

scientific article published on 14 March 2022

Metabolic programming of mesenchymal stromal cells by oxygen tension directs chondrogenic cell fate

scientific article

Methodological approaches in aggregate formation and microscopic analysis to assess pseudoislet morphology and cellular interactions

scientific article published on 13 July 2022

Methods of Monitoring Cell Fate and Tissue Growth in Three-Dimensional Scaffold-Based Strategies for In Vitro Tissue Engineering

scientific article published on 29 January 2016

Micro-Topographies Promote Late Chondrogenic Differentiation Markers in the ATDC5 Cell Line

scientific article

Micro-aggregates do not influence bone marrow stromal cell chondrogenesis.

scientific article published on 2 April 2014

Micro-fabricated scaffolds lead to efficient remission of diabetes in mice.

scientific article

MicroRNA Levels as Prognostic Markers for the Differentiation Potential of Human Mesenchymal Stromal Cell Donors

scientific article

Microbioreactors for Raman Microscopy of Stromal Cell Differentiation

scientific article published on 01 March 2010

Microfabrication of shaped mm-scale tissues to study vascular development

article

Microfabrication techniques in materiomics

Microfluidic platform with four orthogonal and overlapping gradients for soluble compound screening in regenerative medicine research

scientific article published on 12 November 2014

Microporous calcium phosphate ceramics driving osteogenesis through surface architecture.

scientific article published on 18 July 2014

Microspheres for protein delivery prepared from amphiphilic multiblock copolymers

scientific article published on 01 July 2000

Microspheres for protein delivery prepared from amphiphilic multiblock copolymers. 2. Modulation of release rate

scientific article published in July 2000

Microtiter plate-sized standalone chip holder for microenvironmental physiological control in gas-impermeable microfluidic devices

scientific article published on 22 April 2014

Microwell scaffolds for the extrahepatic transplantation of islets of Langerhans

scientific article

Mimicking natural cell environments: design, fabrication and application of bio-chemical gradients on polymeric biomaterial substrates

scientific article published on 06 June 2016

Mining for osteogenic surface topographies: In silico design to in vivo osseo-integration

scientific article published on 12 May 2017

Model to Design Multilayer Tissue Engineering Scaffolds

scholarly article by Bernke J. Papenburg et al published December 2011 in Macromolecular Symposia

Modeling mechanical signals on the surface of µCT and CAD based rapid prototype scaffold models to predict (early stage) tissue development.

scientific article

Modulation of chondrocyte phenotype for tissue engineering by designing the biologic-polymer carrier interface

scientific article published in November 2006

Mold-Based Application of Laser-Induced Periodic Surface Structures (LIPSS) on Biomaterials for Nanoscale Patterning

scientific article published on 3 September 2015

Molecular Tuning of a Benzene‐1,3,5‐Tricarboxamide Supramolecular Fibrous Hydrogel Enables Control over Viscoelasticity and Creates Tunable ECM‐Mimetic Hydrogels and Bioinks

scientific article published in 2023

Molecular mechanisms of biomaterial-driven osteogenic differentiation in human mesenchymal stromal cells

scientific article published on 11 June 2013

Monitoring nutrient transport in tissue-engineered grafts

scientific article published on 24 January 2013

Monolithic and assembled polymer-ceramic composites for bone regeneration

scientific article published on 7 November 2012

Monolithic calcium phosphate/poly(lactic acid) composite versus calcium phosphate-coated poly(lactic acid) for support of osteogenic differentiation of human mesenchymal stromal cells

scientific article published on 19 January 2016

Nano-apatite/polymer composites: mechanical and physicochemical characteristics

scientific article published on 01 October 1997

Nano-scale study of the nucleation and growth of calcium phosphate coating on titanium implants

scientific article published in June 2004

NanoTopoChip: High-throughput nanotopographical cell instruction

scientific article published on 17 August 2017

Nanostructured 3D constructs based on chitosan and chondroitin sulphate multilayers for cartilage tissue engineering

scientific article

New insights into the effects of biomaterial chemistry and topography on the morphology of kidney epithelial cells

scientific article published on 15 December 2016

Noninvasive Imaging of Bone-Specific Collagen I Expression in a Luciferase Transgenic Mouse Model

scientific article published on 10 May 2010

O-Phenanthroline as modulator of the hypoxic and catabolic response in cartilage tissue-engineering models

scientific article published on 21 November 2014

On the horizon: instructive nanomaterials hold the potential to mimic tissue complexity.

scientific article

Online measurement of oxygen consumption by goat bone marrow stromal cells in a combined cell-seeding and proliferation perfusion bioreactor

scientific article published in November 2006

Optimization of bone tissue engineering in goats: a peroperative seeding method using cryopreserved cells and localized bone formation in calcium phosphate scaffolds.

scientific article published in February 2004

Optimization of bone-tissue engineering in goats.

scientific article

Osteochondral Regeneration: Tuning Cell Differentiation into a 3D Scaffold Presenting a Pore Shape Gradient for Osteochondral Regeneration (Adv. Healthcare Mater. 14/2016).

scientific article published in July 2016

Osteoclastic resorption of biomimetic calcium phosphate coatings in vitro.

scientific article

Osteoclastic resorption of calcium phosphates is potentiated in postosteogenic culture conditions

article

Osteoconduction and osteoinduction of low-temperature 3D printed bioceramic implants

scientific article published on 4 December 2007

Osteogenecity of octacalcium phosphate coatings applied on porous metal implants.

scientific article published in September 2003

Osteogenicity of autologous bone transplants in the goat

scientific article published on 01 February 2004

Osteoinduction by biomaterials--physicochemical and structural influences

scientific article published in June 2006

Osteoinductive biomaterials: current knowledge of properties, experimental models and biological mechanisms

scientific article published on May 15, 2011

Osteoinductive ceramics as a synthetic alternative to autologous bone grafting.

scientific article

Overcoming kidney organoid challenges for regenerative medicine

scientific article published on 30 April 2020

Overlooked? Underestimated? Effects of Substrate Curvature on Cell Behavior

scientific article published on 16 March 2019

Oxidative stress in pancreatic alpha and beta cells as a selection criterion for biocompatible biomaterials

scientific article published on 24 October 2020

Oxygen and nutrient delivery in tissue engineering: Approaches to graft vascularization

scientific article published on 30 July 2019

Oxygen gradients in tissue-engineered PEGT/PBT cartilaginous constructs: measurement and modeling

scientific article published in April 2004

Patterns of amino acid metabolism by proliferating human mesenchymal stem cells

scientific article published on 21 November 2011

Peptide functionalized polyhydroxyalkanoate nanofibrous scaffolds enhance Schwann cells activity

scientific article published on 02 May 2014

Physicochemical composition of osteoporotic bone in the trichothiodystrophy premature aging mouse determined by confocal Raman microscopy

scientific article

Plug and play: combining materials and technologies to improve bone regenerative strategies

scientific article published on 14 May 2013

Polar-like trophoblast stem cells form an embryonic-abembryonic axis in blastoids.: Supplementary data

Poly(N-isopropylacrylamide)–poly(ferrocenylsilane) dual-responsive hydrogels: synthesis, characterization and antimicrobial applications

Poly(caprolactone-co-trimethylenecarbonate) urethane acrylate resins for digital light processing of bioresorbable tissue engineering implants

scientific article published on 01 November 2019

Polyacids as bonding agents in hydroxyapatite polyester-ether (Polyactive 30/70) composites

scientific article published on 01 January 1998

Polymer hollow fiber three-dimensional matrices with controllable cavity and shell thickness

scientific article published on 28 August 2006

Polymer scaffolds fabricated with pore-size gradients as a model for studying the zonal organization within tissue-engineered cartilage constructs

scientific article published in September 2005

Porous Ti6Al4V scaffold directly fabricating by rapid prototyping: preparation and in vitro experiment

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Porous Ti6Al4V scaffolds directly fabricated by 3D fibre deposition technique: Effect of nozzle diameter

scientific article published on 01 December 2005

Potential of embryonic stem cells forin vivobone regeneration

scientific article published on 01 November 2008

Predicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1

scientific article published on 26 March 2013

Predictive value of in vitro and in vivo assays in bone and cartilage repair--what do they really tell us about the clinical performance?

scientific article published in January 2006

Primary 'Acquired and Recurrent CholesteatomaversusResidual Cholesteatoma: A Light- and Electron-microscopical Study

scientific article published on 01 November 1988

Primary chondrocytes enhance cartilage tissue formation upon co-culture with a range of cell types

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Pro-osteogenic trophic effects by PKA activation in human mesenchymal stromal cells.

scientific article published on 31 May 2011

Quantifying in vitro growth and metabolism kinetics of human mesenchymal stem cells using a mathematical model

scientific article published in September 2009

Quantitative analysis of the inflammatory reaction surrounding sutures commonly used in operative procedures and the relation to postsurgical adhesion formation

scientific article published on 01 November 1995

Raman Microspectroscopy: A Noninvasive Analysis Tool for Monitoring of Collagen-Containing Extracellular Matrix Formation in a Medium-Throughput Culture System

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Raman imaging of PLGA microsphere degradation inside macrophages

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Rapid prototyping of anatomically shaped, tissue-engineered implants for restoring congruent articulating surfaces in small joints

scientific article published on 22 May 2009

Reactions of cells at implant surfaces

scientific article published on 01 March 1991

Recognizing different tissues in human fetal femur cartilage by label-free Raman microspectroscopy

scientific article published on November 2012

Redox regulation in regenerative medicine and tissue engineering: The paradox of oxygen

scientific article published on 21 August 2018

Regenerating articular tissue by converging technologies

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Regeneration-on-a-chip? The perspectives on use of microfluidics in regenerative medicine

scientific article published on September 2013

Relating cell proliferation to in vivo bone formation in porous Ca/P scaffolds

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Relation between in vitro and in vivo osteogenic potential of cultured human bone marrow stromal cells.

scientific article published in October 2004

Relevance of bone graft viability in a goat transverse process model

scientific article published on 01 August 2009

Relevance of osteoinductive biomaterials in critical-sized orthotopic defect

scientific article published in May 2006

Scaffolds for tissue engineering of cartilage.

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Scaffolds with a standardized macro-architecture fabricated from several calcium phosphate ceramics using an indirect rapid prototyping technique.

scientific article published on 11 November 2010

Scalable topographies to support proliferation and Oct4 expression by human induced pluripotent stem cells.

scientific article published on 13 January 2016

Self-attaching and cell-attracting in-situ forming dextran-tyramine conjugates hydrogels for arthroscopic cartilage repair

scientific article published on 20 January 2012

Self-organization of post-implantation-like embryonic tissues from blastoids

Skeletal tissue engineering using embryonic stem cells

scientific article published on March 2010

Small molecule inhibitors of WNT/β-catenin signaling block IL-1β- and TNFα-induced cartilage degradation

scientific article published on 21 August 2013

Soft-molecular imprinted electrospun scaffolds to mimic specific biological tissues

scientific article published on 20 August 2018

Sonic Hedgehog-activated engineered blood vessels enhance bone tissue formation

scientific article published on 2 March 2012

Spatial distribution and survival of human and goat mesenchymal stromal cells on hydroxyapatite andβ-tricalcium phosphate

scientific article published on 18 December 2012

Spatiotemporal proliferation of human stromal cells adjusts to nutrient availability and leads to stanniocalcin-1 expression in vitro and in vivo

scientific article published on 15 May 2015

Spheroid culture as a tool for creating 3D complex tissues

scientific article published on 18 January 2013

Stability and Cell Adhesion Properties of Poly(N-isopropylacrylamide) Brushes with Variable Grafting Densities

Static and dynamic fibroblast seeding and cultivation in porous PEO/PBT scaffolds

scientific article published in December 1999

Stem cells

Stimulation of skin repair is dependent on fibroblast source and presence of extracellular matrix

scientific article published in July 2004

Stimulatory effect of cobalt ions incorporated into calcium phosphate coatings on neovascularization in an in vivo intramuscular model in goats

scientific article published on 18 March 2016

Streamlining the generation of an osteogenic graft by 3D culture of unprocessed bone marrow on ceramic scaffolds

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Structural arrangements at the interface between plasma sprayed calcium phosphates and bone

scientific article published on 01 June 1994

Supporting data of spatiotemporal proliferation of human stromal cells adjusts to nutrient availability and leads to stanniocalcin-1 expression in vitro and in vivo

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Suppression of the immune system as a critical step for bone formation from allogeneic osteoprogenitors implanted in rats.

scientific article published on 17 November 2013

Surface energy and stiffness discrete gradients in additive manufactured scaffolds for osteochondral regeneration

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Surface modification of electrospun fibre meshes by oxygen plasma for bone regeneration

scientific article published on 11 December 2012

Surface modification of nano-apatite by grafting organic polymer

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Surface modifications by gas plasma control osteogenic differentiation of MC3T3-E1 cells

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Sustained delivery of growth factors with high loading efficiency in a layer by layer assembly

scientific article published on 12 November 2019

Synthesis and characterization of hyaluronic acid-poly(ethylene glycol) hydrogels via Michael addition: An injectable biomaterial for cartilage repair.

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Synthetic scaffold morphology controls human dermal connective tissue formation

scientific article published in September 2005

T cell factor 4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating nuclear factor κB signaling

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Tailorable Surface Morphology of 3D Scaffolds by Combining Additive Manufacturing with Thermally Induced Phase Separation

scientific article published on 3 July 2017

Tailored release of TGF-beta1 from porous scaffolds for cartilage tissue engineering

scientific article published on 29 September 2006

Tailoring chemical and physical properties of fibrous scaffolds from block copolyesters containing ether and thio-ether linkages for skeletal differentiation of human mesenchymal stromal cells

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Tailoring surface nanoroughness of electrospun scaffolds for skeletal tissue engineering.

scientific article published on 6 July 2017

The Components of Bone and What They Can Teach Us about Regeneration

scientific article published on 22 December 2017

The Effect of Donor Variation and Senescence on Endothelial Differentiation of Human Mesenchymal Stromal Cells

scientific article published on 26 June 2013

The Effect of External Stimuli on Rat Middle Ear Epithelium in Culture

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The Effects of Crystal Phase and Particle Morphology of Calcium Phosphates on Proliferation and Differentiation of Human Mesenchymal Stromal Cells

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The Use of Finite Element Analyses to Design and Fabricate Three-Dimensional Scaffolds for Skeletal Tissue Engineering

scientific article published on 17 May 2017

The behavior of alloplastic tympanic membranes inStaphylococcus aureus-induced middle ear infection. I. Quantitative biocompatibility evaluation

scientific article published on 01 June 1990

The biocompatibility of hydroxyapatite ceramic: a study of retrieved human middle ear implants

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The biological performance of calcium phosphate ceramics in an infected implantation site: I. Biological performance of hydroxyapatite during Staphylococcus aureus infection

scientific article published on 01 September 1986

The bone-bonding polymer Polyactive� 80/20 induces hydroxycarbonate apatite formationin vitro

scientific article published on 01 January 1997

The different behaviors of skeletal muscle cells and chondrocytes on PEGT/PBT block copolymers are related to the surface properties of the substrate.

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The effect of PEGT/PBT scaffold architecture on oxygen gradients in tissue engineered cartilaginous constructs.

scientific article published on November 2004

The effect of PEGT/PBT scaffold architecture on the composition of tissue engineered cartilage.

scientific article published in January 2005

The effect of PKC activation and inhibition on osteogenic differentiation of human mesenchymal stem cells

scientific article published in July 2010

The effect of bone marrow aspiration strategy on the yield and quality of human mesenchymal stem cells

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The effect of calcium phosphate microstructure on bone-related cells in vitro

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The effect of cell-based bone tissue engineering in a goat transverse process model.

scientific article published on 19 June 2006

The effect of external stimuli on cultured rat middle ear epithelium. I. Extracellular calcium concentration

scientific article published in January 1990

The effect of perfluorocarbon-based artificial oxygen carriers on tissue-engineered trachea

scientific article published in September 2009

The effect of platelet lysate supplementation of a dextran-based hydrogel on cartilage formation

scientific article published on 18 February 2012

The effect of scaffold architecture on properties of direct 3D fiber deposition of porous Ti6Al4V for orthopedic implants

scientific article published on 01 January 2010

The effect of scaffold-cell entrapment capacity and physico-chemical properties on cartilage regeneration

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The effect of timing of mechanical stimulation on proliferation and differentiation of goat bone marrow stem cells cultured on braided PLGA scaffolds

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The effects of inorganic additives to calcium phosphate on in vitro behavior of osteoblasts and osteoclasts

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The homing of bone marrow MSCs to non-osseous sites for ectopic bone formation induced by osteoinductive calcium phosphate

scientific article published on 5 January 2013

The influence of genetic factors on the osteoinductive potential of calcium phosphate ceramics in mice

scientific article published on 15 May 2012

The osteochondral interface as a gradient tissue: from development to the fabrication of gradient scaffolds for regenerative medicine

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The physics of tissue formation with mesenchymal stem cells

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The polymer Polyactive as a bone-filling substance: an experimental study in rabbits

scientific article published on 01 August 1998

The regulation of expanded human nasal chondrocyte re-differentiation capacity by substrate composition and gas plasma surface modification.

scientific article published on 24 August 2005

The response of human mesenchymal stem cells to osteogenic signals and its impact on bone tissue engineering

scientific article published on September 2007

The role of alpha cells in the self-assembly of bioengineered islets

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The role of collagen crosslinking in differentiation of human mesenchymal stem cells and MC3T3-E1 cells

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The role of three-dimensional polymeric scaffold configuration on the uniformity of connective tissue formation by adipose stromal cells

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The size of surface microstructures as an osteogenic factor in calcium phosphate ceramics.

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The use of PEGT/PBT as a dermal scaffold for skin tissue engineering

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The use of endothelial progenitor cells for prevascularized bone tissue engineering

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Therapeutic applications of mesenchymal stromal cells: paracrine effects and potential improvements

scientific article published on 22 December 2011

Thermoforming of film-based biomedical microdevices

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Thin polymer brush decouples biomaterial's micro-/nanotopology and stem cell adhesion

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Three-dimensional fiber-deposited PEOT/PBT copolymer scaffolds for tissue engineering: influence of porosity, molecular network mesh size, and swelling in aqueous media on dynamic mechanical properties

scientific article published in December 2005

Timing, rather than the concentration of cyclic AMP, correlates to osteogenic differentiation of human mesenchymal stem cells

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Tissue Engineering

scholarly article published 2014

Tissue assembly and organization: developmental mechanisms in microfabricated tissues

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Tissue deformation spatially modulates VEGF signaling and angiogenesis

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Tissue engineering of bovine articular cartilage within porous poly(ether ester) copolymer scaffolds with different structures

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Tissue engineering of dermal substitutes based on porous PEGT/PBT copolymer scaffolds: comparison of culture conditions

scientific article published in March 2003

Tissue engineering of ligaments: a comparison of bone marrow stromal cells, anterior cruciate ligament, and skin fibroblasts as cell source

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Tissue engineering – an introduction

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Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis.

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Toward mimicking the bone structure: design of novel hierarchical scaffolds with a tailored radial porosity gradient

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Towards 4D printed scaffolds for tissue engineering: exploiting 3D shape memory polymers to deliver time-controlled stimulus on cultured cells.

scientific article published on 20 July 2017

Towards an in vitro model mimicking the foreign body response: tailoring the surface properties of biomaterials to modulate extracellular matrix

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Trends in biomaterials research: An analysis of the scientific programme of the World Biomaterials Congress 2008

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Trophic effects of mesenchymal stem cells in chondrocyte co-cultures are independent of culture conditions and cell sources

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Trophic effects of mesenchymal stem cells increase chondrocyte proliferation and matrix formation.

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Tuning Cell Differentiation into a 3D Scaffold Presenting a Pore Shape Gradient for Osteochondral Regeneration.

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Tympanic Membrane Structure during aStaphylococcus Aureus-induced. Middle Ear Infection:A Study in the Rat Middle Ear

scientific article published on 01 March 1989

Ultraviolet light crosslinking of poly(trimethylene carbonate) for elastomeric tissue engineering scaffolds

scientific article published on 23 August 2010

Use of an osteoinductive biomaterial as a bone morphogenetic protein carrier.

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Use of bone-bonding hydrogel copolymers in bone: Anin vitro andin vivo study of expanding PEO-PBT copolymers in goat femora

scientific article published on 01 March 2000

Vascularization in tissue engineering

scientific article published on 26 June 2008

Viable osteogenic cells are obligatory for tissue-engineered ectopic bone formation in goats

scientific article published in April 2003

Viscoelastic Oxidized Alginates with Reversible Imine Type Crosslinks: Self-Healing, Injectable, and Bioprintable Hydrogels

scientific article published on 21 November 2018

Wettability influences cell behavior on superhydrophobic surfaces with different topographies.

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What Should We Print? Emerging Principles to Rationally Design Tissues Prone to Self-Organization

Wnt signaling inhibits osteogenic differentiation of human mesenchymal stem cells

scientific article published on May 2004

Zero-order release of lysozyme from poly(ethylene glycol)/poly(butylene terephthalate) matrices

scientific article published in February 2000

cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo

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cAMP/PKA signaling inhibits osteogenic differentiation and bone formation in rodent models

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