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List of works by Harald Breivik

"Cervicogenic" headache. An hypothesis

scientific article published on December 1983

1 Benefits, risks and economics of post-operative pain management programmes

2 Safe and effective post-operative pain relief: introduction and continuous quality-improvement of comprehensive post-operative pain management programmes

6 Optimal epidural analgesia: importance of drug combinations and correct segmental site of injection

9 Post-operative analgesic trials: some important issues

A 6-months, randomised, placebo-controlled evaluation of efficacy and tolerability of a low-dose 7-day buprenorphine transdermal patch in osteoarthritis patients naïve to potent opioids

article

A comparison of anaesthesia using remifentanil combined with either isoflurane, enflurane or propofol in patients undergoing gynaecological laparoscopy, varicose vein or arthroscopic surgery

scientific article published in August 2000

A high-quality RCT documents that elderly with dementia, the most neglected pain patients, have effective and safe pain relief from paracetamol alone or with buprenorphine patch

scientific article published on November 2014

A new treatable chronic pain diagnosis? Flank pain caused by entrapment of posterior cutaneous branch of intercostal nerves, lateral ACNES coined LACNES.

scientific article published on 25 October 2017

A new treatment principle for neuropathic pain? Approved oncologic drugs: Epidermal growth factor receptor (EGFR) inhibitors dramatically relieve severe neuropathic pain in a case series

A novel infraclavicular brachial plexus block: the lateral and sagittal technique, developed by magnetic resonance imaging studies

scientific article published in January 2004

A randomized, double-blind, double-dummy comparison of short- and long-acting dihydrocodeine in chronic non-malignant pain

scientific article published on 15 December 2013

A systematic review of comparative studies indicates that paravertebral block is neither superior nor safer than epidural analgesia for pain after thoracotomy

article

Accelerated recovery programmes should complement, not replace, the acute pain services

scientific article published on 01 July 2012

Adding propacetamol to ketorolac increases the tolerance to painful pressure

scientific article published on April 2006

Additive analgesic effect of codeine and paracetamol can be detected in strong, but not moderate, pain after Caesarean section. Baseline pain-intensity is a determinant of assay-sensitivity in a postoperative analgesic trial

scientific article published on April 1996

Adrenaline markedly improves thoracic epidural analgesia produced by a low-dose infusion of bupivacaine, fentanyl and adrenaline after major surgery. A randomised, double-blind, cross-over study with and without adrenaline

scientific article

Advances in treatment of neuropathic pain

scientific article published on 01 January 2002

An overlooked cause of head- and neck-pain: Chronic canalithiasis, or Benign Paroxysmal Positional Vertigo – BPPV

Analysis of pain-intensity measurements

scientific article published on 4 September 2016

Anti-emetic and propulsive peristaltic properties of metoclopramide

scientific article published in April 1971

Appropriate and responsible use of opioids in chronic non-cancer pain

scientific article published on 01 January 2003

Assessment of pain

scientific article

Associative learning mechanisms may trigger increased burden of chronic pain; unlearning and extinguishing learned maladaptive responses should help chronic pain patients

scientific article published on 15 December 2015

Avoiding psychic adverse effects during induction of neurolept anaesthesia with levomepromazine. A double-blind study of levomepromazine and droperidol.

scientific article published on April 1982

Avoiding the Scylla of NSAIDs and the Charybdis of High-Dose Opioids

Breakthrough pain in malignant and non-malignant diseases: a review of prevalence, characteristics and mechanisms

scientific article

Burden of disease is often aggravated by opioid treatment of chronic pain patients: Etiology and prevention

scientific article published on 16 September 2014

CNS-mechanisms contribute to chronification of pain

scientific article published on 4 April 2017

Cancer-pain intractable to high-doses systemic opioids can be relieved by intraspinal local anaesthetic plus an opioid and an alfa2-adrenoceptor agonist

scientific article published on 27 June 2017

Cancer-related pain: a pan-European survey of prevalence, treatment, and patient attitudes

scientific article

Cervicobrachialgia after spinal surgery

scientific article published on 28 October 2014

Changes in Oncotic Pressure, Osmolality and Electrolytes Following Transurethral Resection of the Prostate Using Glycine as Irrigating Solution

scientific article published on 01 January 1983

Chronic compartment syndrome is an under-recognized cause of leg-pain

scientific article published on 6 May 2016

Chronic pain and psychological distress among long-term social assistance recipients - An intolerable burden on those on the lowest steps of the socioeconomic ladder

scientific article published on 27 February 2016

Chronic pain and sensory changes after augmentation mammoplasty: Long term effects of preincisional administration of methylprednisolone

Collaborative randomized clinical study of cardiopulmonary-cerebral resuscitation.

scientific article published in May 1981

Combining an oral opioid-receptor agonist and the antagonist naloxone: A smart drug design that removes some but not all adverse effects of the opioid analgesic

scientific article published on 01 April 2014

Complex Regional Pain Syndrome (CRPS) after viper-bite in a pregnant young woman: Pathophysiology and treatment options.

scientific article

Computer work can cause deep tissue hyperalgesia: Implications for prevention and treatment

Conditioned pain modulation: A useful test paradigm in research and in clinical practice

Continuous subcutaneous administration of the N-methyl-D-aspartic acid (NMDA) receptor antagonist ketamine in the treatment of post-herpetic neuralgia

scientific article published on May 1995

Corrigendum to “A 6-months, randomised, placebo-controlled evaluation of efficacy and tolerability of 7 day buprenorphine transdermal patch in osteoarthritis patients naïve to potent-opioids” [Scandinavian Journal of Pain 1 (2010) 122-141]

scholarly article published in Scandinavian Journal of Pain

Definition, diagnosis and treatment strategies for opioid-induced bowel dysfunction-Recommendations of the Nordic Working Group

scientific article published on 4 February 2016

Depression and anxiety in adolescents aggravate abdominal pain, and abdominal pain deepens depression which increases suffering from chronic pain

Depressive symptoms associated with poor outcome after lumbar spine surgery: Pain and depression impact on each other and aggravate the burden of the sufferer

scientific article published on 7 May 2016

Detecting postoperative urinary retention with an ultrasound scanner

scientific article published in March 2002

Dialectical behavioural therapy for complex chronic pain conditions

Difficult drug reimbursement system for pain patients

scientific article published in January 2013

Distribution of local anesthetic in axillary brachial plexus block: a clinical and magnetic resonance imaging study

scientific article

Do women with Caesarean section have to choose between pain relief and breastfeeding?

scientific article

Effective pain relief from intra-articular saline with or without morphine 2 mg in patients with moderate-to-severe pain after knee arthroscopy: a randomized, double-blind controlled clinical study

scientific article

Effects of 0.5 and 1.0 MAC isoflurane, sevoflurane and desflurane on intracranial and cerebral perfusion pressures in children

scientific article published in September 2003

Endocrinopathies in women during opioid therapy cause loss of androgens, fatigue, listlessness, loss of libido and quality of life: stop prescribing opioids or follow the 2016 Centers for Disease Control and Prevention guidelines?

scientific article

Epidural fentanyl markedly improves thoracic epidural analgesia in a low-dose infusion of bupivacaine, adrenaline and fentanyl. A randomized, double-blind crossover study with and without fentanyl

scientific article

Epidural versus general anaesthesia for total hip arthroplasty in elderly patients.

scientific article published in August 1980

Epinephrine markedly improves thoracic epidural analgesia produced by a small-dose infusion of ropivacaine, fentanyl, and epinephrine after major thoracic or abdominal surgery: a randomized, double-blinded crossover study with and without epinephrin

scientific article published on June 2002

Erythromelalgia – A dramatic pain of genetic origin, revealing pain mechanisms with implications for neuropathic pain in general

European Pain Management Discussion Forum

European Pain Management Discussion Forum

European Pain Management Discussion Forum

European Pain Management Discussion Forum

Evaluation of pain in children with communication difficulties: r-FLACC translated and validated in Nordic languages

Even a “simple” pain condition such as “Tennis Elbow” is not only a somatic experience: body and mind are inseparable entities

article published in 2013

Fear and catastrophizing thoughts aggravate risks of chronic pain after a fracture

article by Eirikur Lindal & Harald Breivik published 1 January 2010 in Scandinavian Journal of Pain

Fifty years on the Visual Analogue Scale (VAS) for pain-intensity is still good for acute pain. But multidimensional assessment is needed for chronic pain

scientific article published on 27 February 2016

Fluid balance and pulmonary functions during and after coronary artery bypass surgery: Ringer's acetate compared with dextran, polygeline, or albumin.

scientific article published in July 1995

Genital pain related to sexual activity in young women: A large group who suffer in silence

Glucocorticoids reduce acute postoperative pain

scientific article

HIGH risk of chronic pain in women with LOW education, LOW socio-economic status, and LOW mood

Herpes Zoster Immunization in Older Adults Has Big Benefits

scientific article published on 25 August 2015

Herpes zoster immunization in older adults has big benefits

scientific article published in June 2015

High risk of depression and suicide attempt among chronic pain patients: Always explore catastrophizing and suicide thoughts when evaluating chronic pain patients

High-resolution MRI demonstrates detailed anatomy of the axillary brachial plexus. A pilot study

scientific article

How to implement an acute pain service

scientific article

Hypertonic saline (7.2%) in 6% hydroxyethyl starch reduces intracranial pressure and improves hemodynamics in a placebo-controlled study involving stable patients with subarachnoid hemorrhage*

Ibuprofen plus codeine, ibuprofen, and placebo in a single- and multidose cross-over comparison for coxarthrosis pain

scientific article published on 01 September 1992

Importance of early diagnosis of complex regional pain syndrome (CRPS-1 and C RPS-2): Delayed diagnosis of CRPS is a major problem

scientific article published on 19 December 2015

Important development: Extended Acute Pain Service for patients at high risk of chronic pain after surgery

scientific article published on 7 May 2016

Improving pain treatment in children

scientific article published on 13 September 2016

Increasing use of opioids from 2004 to 2007 - pharmacoepidemiological data from a complete national prescription database in Norway.

scientific article

Infectious complications of epidural anaesthesia and analgesia

scientific article published on October 1999

International Association for the Study of Pain: update on WHO-IASP activities

scientific article

Intra-articular (IA) catheter administration of postoperative analgesics. A new trial design allows evaluation of baseline pain, demonstrates large variation in need of analgesics, and finds no analgesic effect of IA ketamine compared with IA saline

scientific article

Intra-articular morphine for pain relief after knee arthroscopy

scientific article

Intravenous non-opioids for immediate postop pain relief in day-case programmes: Paracetamol (acetaminophen) and ketorolac are good choices reducing opioid needs and opioid side-effects

Invisible pain – Complications from too little or too much empathy among helpers of chronic pain patients

Keeping an open mind: Achieving balance between too liberal and too restrictive prescription of opioids for chronic non-cancer pain: Using a two-edged sword

Ketamine has anti-hyperalgesic effects and relieves acute pain, but does not prevent persistent postoperative pain (PPP)

Knee osteoarthritis patients with intact pain modulating systems may have low risk of persistent pain after knee joint replacement

article by Audun Stubhaug & Harald Breivik published 1 January 2015 in Scandinavian Journal of Pain

Lack of analgesic effect of 50 and 100 mg oral tramadol after orthopaedic surgery: a randomized, double-blind, placebo and standard active drug comparison.

scientific article published in July 1995

Learning from the past for the present: paravertebral blocks for thoracic surgery are not without risk

scientific article

Lengevirkende versus langtidsvirkende

Les corticoïdes diminuent-ils la douleur et les nausées–vomissements postopératoires ?

Life-supporting first aid self-training

scientific article published on 01 November 1980

Liquid-scintillation detection of preseparated 257Rf with the SISAK-system

Local infiltration analgesia (LIA) and repeated bolus or continuous infusion peripheral nerve blocks for acute postoperative pain: Be ware of local anaesthetic toxicity, especially in elderly patients with cardiac co-morbidities!

article

Local infiltration analgesia (LIA), risk of local anaesthetic systemic toxicity (LAST) and kidney failure from NSAID in elderly patients

scientific article published on 20 September 2016

Long-term treatment of chronic neuropathic pain with the NMDA (N-methyl-D-aspartate) receptor antagonist ketamine

scientific article published in March 1997

Low health related quality of life (QoL) in older adults is associated with chronic pain in women and with disturbed sleep in men

article

METOCLOPRAMIDE AND PERPHENAZINE IN THE PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING: Double-blind Comparison

scientific article published on 01 July 1970

Management of acute postoperative pain: still a long way to go!

scientific article published on 13 May 2008

Mapping of punctuate hyperalgesia around a surgical incision demonstrates that ketamine is a powerful suppressor of central sensitization to pain following surgery

scientific article published on October 1997

Merits of publishing a negative and prematurely ended study on intrathecal methylprednisolone for severe and longstanding complex regional pain syndrome (CRPS-I).

scientific article published on 15 March 2010

Methylprednisolone and ketorolac rapidly reduce hyperalgesia around a skin burn injury and increase pressure pain thresholds

scientific article

Methylprednisolone intravenously 1 day after surgery has sustained analgesic and opioid-sparing effects

scientific article

Methylprednisolone reduces pain, emesis, and fatigue after breast augmentation surgery: a single-dose, randomized, parallel-group study with methylprednisolone 125 mg, parecoxib 40 mg, and placebo

scientific article published in February 2006

Mirror-therapy: An important tool in the management of Complex Regional Pain Syndrome (CRPS)

Moderate-to-severe pain after knee arthroscopy is relieved by intraarticular saline: a randomized controlled trial

scientific article

Monitoring urinary bladder volume and detecting post-operative urinary retention in children with an ultrasound scanner

scientific article

Monocyte functions are depressed during and after surgery under general anaesthesia but not under epidural anaesthesia.

scientific article published in August 1982

More postoperative pain reported by women than by men - Again

scientific article published on 7 June 2016

Musculus piriformis syndrome: Localization and injection therapy—Comment to letter from Mayo-Moldes M et al. [1]

Neuroinflammation explains aspects of chronic pain and opens new avenues for therapeutic interventions

Nitrous oxide in oxygen (50:50) is analgesic that requires optimal inhalation procedure

Nordic guidelines for neuraxial blocks in disturbed haemostasis from the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

scientific article published on 19 October 2009

Norway: development of palliative care

scientific article

Norwegian patients with chronic pain conditions that can be managed with reasonable cost/benefit now have a legally binding right to treatment in Norway

Opioid-induced constipation, use of laxatives, and health-related quality of life

scientific article published on 25 January 2016

Opioids in chronic non-cancer pain, indications and controversies

scientific article

Optimal thoracic epidural analgesia–Again

Oral immediate and prolonged release oxycodone for safe and effective patient controlled analgesia after surgery Can opioid for acute postoperative pain be improved by adding a peripheral opioid antagonist?

Outcome of spine surgery: In a clinical field with few randomized controlled studies, a national spine surgery register creates evidence for practice guidelines

article

Pain Management Discussion Forum

Pain management

Pain management discussion forum

scientific article published on December 2013

Pain management discussion forum

scientific article published on 2 August 2013

Pain management discussion forum: prevention of chronic postoperative pain

scientific article published on September 2014

Pain management discussion forum: serious interaction among frequently used drugs for chronic pain

scientific article published on 7 May 2014

Pain relief during childbirth: Efficacy and safety of prolonging labour-analgesia with morphine directly into the lumbar cerebro-spinal-fluid (CSF).

scientific article published on 22 September 2016

Pain relief with paravertebral blocks or epidural analgesia? Those who do not know the history of paravertebral blocks are condemned to rediscover the complications

Pain treatment with intrathecal corticosteroids: Much ado about nothing? But epidural corticosteroids for radicular pain is still an option

Paracetamol, tiaramide and placebo for pain relief after orthopedic surgery.

scientific article published on June 1981

Peroperative hydration with lactated Ringer's solution versus a saltfree restrictive fluid regimen. Effects on postoperative fluid and electrolyte metabolism and renal function in patients undergoing partial gastrectomy ⬇️

scientific article

Persistent post-surgical pain (PPP) reduced by high-quality management of acute pain extended to sub-acute pain at home

Piroxicam, acetylsalicylic acid and placebo for postoperative pain.

scientific article published on February 1984

Plasma pro-inflammatory markers in chronic neuropathic pain: Why elevated levels may be relevant for diagnosis and treatment of patients suffering chronic pain

Postoperative urinary retention

scientific article published in April 2002

Pre-procedure anxiety aggravates pain—A problem also in adult patients

Predictable reduction of intracranial hypertension with hypertonic saline hydroxyethyl starch: a prospective clinical trial in critically ill patients with subarachnoid haemorrhage

scientific article published in October 2004

Predictors of electromechanical dissociation during cardiac arrest

scientific article published on 01 June 1988

Preface

Premedication for day-case surgery: double-blind comparison of ketobemidone + dimethylaminodiphenylbuten (A-29) and morphine + scopolamine

scientific article published on October 1986

Premedication with midazolam in out-patient general anaesthesia. A comparison with morphine-scopolamine and placebo.

scientific article published in August 1987

Prescription pattern of codeine for non-malignant pain: a pharmacoepidemiological study from the Norwegian Prescription Database.

scientific article published on May 2009

Published evidence from randomised trials indicates that pain after thoracotomy is more effectively relieved by thoracic epidural analgesia than by paravertebral blocks

scientific article published in May 2013

Qualitative pain research emphasizes that patients need true information and physicians and nurses need more knowledge of complex regional pain syndrome (CRPS).

scientific article published on 16 March 2017

Regional analgesia--risks and benefits

scientific article published on February 2010

Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo

scientific article

Removal of persistent organic pollutants from Atlantic salmon (Salmo salar L.) diets: Influence on growth, feed utilization efficiency and product quality

Removal of persistent organic pollutants in fish oils using short-path distillation with a working fluid

scientific article published on 22 March 2013

Reply to S.T. Meller: Ketamine: relief from chronic pain through actions at the NMDA receptor

scientific article published in August 1997

Risks of serious complications after neuraxial blocks: apparent decrease due to guidelines for safe practice?

scientific article published in May 2013

S. Hestenes og medarbeidere svarer:

Safe perioperative spinal and epidural analgesia: importance of drug combinations, segmental site of injection, training and monitoring.

scientific article published in October 1995

Scandinavian Journal of Pain: A networking and publishing tool for pain researchers and pain clinicians in the Nordic countries

Social anxiety and pain-related fear impact each other and aggravate the burden of chronic pain patients: More individually tailored rehabilitation need

scientific article published on 10 June 2016

Stability of an epidural analgesic solution containing adrenaline, bupivacaine and fentanyl

scientific article published in August 2000

Stable long-term opioid medication per se does not always cause loss of driving ability: the doctor and patient must consider additional risk factors for unsafe driving

scientific article published in July 2006

Statistical pearls: Importance of effect-size, blinding, randomization, publication bias, and the overestimated p-values

article

Subacute pain after total knee arthroplasty

scientific article published on 7 May 2014

Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment

scientific article (publication date: May 2006)

Survival after 40 minutes; submersion without cerebral sequeae

scientific article

Synergistic Effect of Acidosis and Succinylcholine-Induced Hyperkalemia in Spinal Cord Transected Rats

scientific article published on 01 February 1984

Tapering and discontinuation of methadone for chronic pain

scientific article published on June 2015

Thank you, Professor Ulf Lindblom

article by Harald Breivik published August 2003 in European Journal of Pain

The Norwegian version of the Neck Disability Index (NDI) is reliable and sensitive to changes in pain-intensity and consequences of pain-in-the-neck

The future role of the anaesthesiologist in pain management.

scientific article

The impact of chronic pain—European patients’ perspective over 12 months

article published in 2012

The individual and societal burden of chronic pain in Europe: the case for strategic prioritisation and action to improve knowledge and availability of appropriate care

scientific article

The life long burden of suffering from postherpetic neuralgia is reduced by adult vaccination and by topical anti-hyperalgesic treatment with lidocaine and capsaicin

The minimally effective concentration of adrenaline in a low-concentration thoracic epidural analgesic infusion of bupivacaine, fentanyl and adrenaline after major surgery. A randomized, double-blind, dose-finding study

scientific article

The most important step forward in modern medicine, “a giant leap for mankind”: Insensibility to pain during surgery and painful procedures

The obesity epidemic makes life difficult for patients with herniated lumbar discs - and for back-surgeons: Increased risk of complications

scientific article published on 20 November 2015

The safety and effectiveness of remifentanil as an adjunct sedative for regional anesthesia

scientific article published in January 1999

The stability of a sulphite-free epidural analgesic solution containing fentanyl, bupivacaine, and adrenaline

scientific article

Thoracic epidural fentanyl has spinal cord analgesic effects

scientific article published in October 2013

Thoracic paravertebral blockade and thoracic epidural analgesia: two extremes of a continuum

scientific article published in April 2011

Those who do not know their pain-history will repeat previous errors in pain management

Training programme in advanced pain medicine for Nordic anaesthesiologists

scientific article published on 01 November 2001

Transmucosal fentanyl for severe cancer pain: Nasal mucosa superior to oral mucosa?

scientific article published on 21 January 2016

Treat the Whole Patient and Be Aware of Drug Interactions

Ultrasound-guided high concentration tetracaine peripheral nerve block: Effective and safe relief while awaiting more permanent intervention for tic douloureux

Validation of a method for gas chromatographic analysis of eicosapentaenoic acid and docosahexaenoic acid as active ingredients in medicinal products

article published in 1992

What do different databases tell about the use of opioids in seven European countries in 2002?

Whether the weather influences pain: High prevalence of chronic pain in Iceland and Norway: Common genes? Or lack of sunshine and vitamin D?

scholarly article by Harald Breivik et al published 1 July 2010 in Scandinavian Journal of Pain

Why are autonomic responses to pressure pain different from those to heat pain and ischaemic pain?

article

Why we publish negative studies – and prescriptions on how to do clinical pain trials well

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