List of works - Sang-Kyou Lee

Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice

scientific article published on December 2011

Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome?like skeletal defects induced by Pdk1 or Cbp mutations in mice

scientific article published in May 2012

Alleviation of abnormal synaptic neurotransmitter release by cell-permeable form of the truncated SNAP-25 upon transcutaneous delivery

scientific article published on 2 April 2013

Alleviation of rheumatoid arthritis by cell-transducible methotrexate upon transcutaneous delivery.

scientific article published on 17 November 2011

Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin.

scientific article

Antioxidant properties of neohesperidin dihydrochalcone: inhibition of hypochlorous acid-induced DNA strand breakage, protein degradation, and cell death

scientific article published on February 2007

Apoptosis of macrophages induced by Trichomonas vaginalis through the phosphorylation of p38 mitogen-activated protein kinase that locates at downstream of mitochondria-dependent caspase activation

scientific article published on 5 December 2005

Attenuation of contact hypersensitivity by cell-permeable heat shock protein 70 in BALB/c mouse model.

scientific article

C-Reactive Protein to Serum Albumin Ratio Is an Independent Predictor of All-Cause Mortality in Patients with ANCA-Associated Vasculitis

scientific article published on 01 September 2018

Calpains are involved in Entamoeba histolytica-induced death of HT-29 colonic epithelial cells.

scientific article published on 14 June 2011

Cell permeable NFAT inhibitory peptide Sim-2-VIVIT inhibits T-cell activation and alleviates allergic airway inflammation and hyper-responsiveness

scientific article published on 10 February 2012

Cell-penetrating DNA-binding protein as a safe and efficient naked DNA delivery carrier in vitro and in vivo.

scientific article published on 30 December 2009

Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation.

scientific article

Cell-permeable mitochondrial ubiquinol-cytochrome c reductase binding protein induces angiogenesis in vitro and in vivo

scientific article

Controlled release of cell-permeable gene complex from poly(L-lactide) scaffold for enhanced stem cell tissue engineering

scientific article published on 21 March 2011

Effect of Hypoxia-Inducible Factor 1α on Early Healing in Extraction Sockets

scientific article published on 08 May 2018

HIF1A overexpression using cell-penetrating DNA-binding protein induces angiogenesis in vitro and in vivo.

scientific article published on 28 June 2017

Helicobacter pylori proinflammatory protein up-regulates NF-kappaB as a cell-translocating Ser/Thr kinase ⬇️

scientific article published on November 22, 2010

Immuno-suppressive function of nucleus-transducible BAF57-ΔPH in T cell activation via degradation of endogenous BAF57

scientific article published on 05 July 2018

Immunosuppressive effects of tautomycetin in vivo and in vitro via T cell-specific apoptosis induction

scientific article

Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients

scientific article published in May 2009

Impaired cell adhesion, apoptosis, and signaling in WASP gene-disrupted Nalm-6 pre-B cells and recovery of cell adhesion using a transducible form of WASp.

scientific article published on 5 February 2012

Intracellular cytoplasm-specific delivery of SH3 and SH2 domains of SLAP inhibits TcR-mediated signaling

scientific article published on 20 March 2015

Intranasal delivery of the cytoplasmic domain of CTLA-4 using a novel protein transduction domain prevents allergic inflammation

scientific article

Intranuclear delivery of synthetic nuclear factor-kappa B p65 reduces inflammasomes after surgery

scientific article published on 08 August 2018

Intranuclear delivery of the transcription modulation domain of Tbet-improved lupus nephritis in (NZB/NZW) F1 lupus-prone mice

scientific article published on 3 February 2018

Intranuclear interactomic inhibition of FoxP3 suppresses functions of Treg cells.

scientific article published on 17 July 2014

Intranuclear interactomic inhibition of NF-κB suppresses LPS-induced severe sepsis.

scientific article published on 6 July 2015

Mesenchymal stem cells pretreated with delivered Hph-1-Hsp70 protein are protected from hypoxia-mediated cell death and rescue heart functions from myocardial injury.

scientific article published in September 2009

Mitochondrial ATP synthase is a target for TNBS-induced protein carbonylation in XS-106 dendritic cells

scientific article

Monitoring the status of T-cell activation in a microfluidic system

scientific article published on 27 May 2011

PLCδ1 protein rescues ischemia-reperfused heart by the regulation of calcium homeostasis

scientific article

Qualitative and quantitative differences in the intensity of Fas-mediated intracellular signals determine life and death in T cells

scientific article published on 24 July 2010

Qualitatively differential regulation of T cell activation and apoptosis by T cell receptor zeta chain ITAMs and their tyrosine residues.

scientific article

Quantification of cellular uptake and in vivo tracking of transduction using real-time monitoring

scientific article published on 4 March 2010

RORγt-specific transcriptional interactomic inhibition suppresses autoimmunity associated with TH17 cells

scientific article

Regulatory T Cells in Tumor Microenvironment and Approach for Anticancer Immunotherapy

scientific article published on 11 February 2020

Skin-penetrating methotrexate alleviates imiquimod-induced psoriasiform dermatitis via decreasing IL-17-producing gamma delta T cells

scientific article published on 01 July 2014

Synergistic inhibition of T-cell activation by a cell-permeable ZAP-70 mutant and ctCTLA-4.

scientific article published on 20 February 2009

T Cell-specific immunosuppression using tautomycetin or PTD-conjugated protein drugs

scientific article

Tautomycetin inhibits growth of colorectal cancer cells through p21cip/WAF1 induction via the extracellular signal-regulated kinase pathway

scientific article published on December 2006

The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils

scientific article

The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells

scientific journal article

The synergistic effect of Tautomycetin on Cyclosporine A-mediated immunosuppression in a rodent islet allograft model

scientific article

Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein

scientific article published on 20 February 2019

Transducible form of p47phox and p67phox compensate for defective NADPH oxidase activity in neutrophils of patients with chronic granulomatous disease.

scientific article published on 25 November 2011

Transduction of the cytoplasmic domain of CTLA-4 inhibits TcR-specific activation signals and prevents collagen-induced arthritis

scholarly article

Trichomonas vaginalis inhibits proinflammatory cytokine production in macrophages by suppressing NF-kappaB activation.

scientific article published in October 2004

dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis

scientific article

List of works by Sang-Kyou Lee

Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice

Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome?like skeletal defects induced by Pdk1 or Cbp mutations in mice

Alleviation of abnormal synaptic neurotransmitter release by cell-permeable form of the truncated SNAP-25 upon transcutaneous delivery

Alleviation of rheumatoid arthritis by cell-transducible methotrexate upon transcutaneous delivery.

Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin.

Antioxidant properties of neohesperidin dihydrochalcone: inhibition of hypochlorous acid-induced DNA strand breakage, protein degradation, and cell death

Apoptosis of macrophages induced by Trichomonas vaginalis through the phosphorylation of p38 mitogen-activated protein kinase that locates at downstream of mitochondria-dependent caspase activation

Attenuation of contact hypersensitivity by cell-permeable heat shock protein 70 in BALB/c mouse model.

C-Reactive Protein to Serum Albumin Ratio Is an Independent Predictor of All-Cause Mortality in Patients with ANCA-Associated Vasculitis

Calpains are involved in Entamoeba histolytica-induced death of HT-29 colonic epithelial cells.

Cell permeable NFAT inhibitory peptide Sim-2-VIVIT inhibits T-cell activation and alleviates allergic airway inflammation and hyper-responsiveness

Cell-penetrating DNA-binding protein as a safe and efficient naked DNA delivery carrier in vitro and in vivo.

Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation.

Cell-permeable mitochondrial ubiquinol-cytochrome c reductase binding protein induces angiogenesis in vitro and in vivo

Controlled release of cell-permeable gene complex from poly(L-lactide) scaffold for enhanced stem cell tissue engineering

Effect of Hypoxia-Inducible Factor 1α on Early Healing in Extraction Sockets

HIF1A overexpression using cell-penetrating DNA-binding protein induces angiogenesis in vitro and in vivo.

Helicobacter pylori proinflammatory protein up-regulates NF-kappaB as a cell-translocating Ser/Thr kinase ⬇️

Immuno-suppressive function of nucleus-transducible BAF57-ΔPH in T cell activation via degradation of endogenous BAF57

Immunosuppressive effects of tautomycetin in vivo and in vitro via T cell-specific apoptosis induction

Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients

Impaired cell adhesion, apoptosis, and signaling in WASP gene-disrupted Nalm-6 pre-B cells and recovery of cell adhesion using a transducible form of WASp.

Intracellular cytoplasm-specific delivery of SH3 and SH2 domains of SLAP inhibits TcR-mediated signaling

Intranasal delivery of the cytoplasmic domain of CTLA-4 using a novel protein transduction domain prevents allergic inflammation

Intranuclear delivery of synthetic nuclear factor-kappa B p65 reduces inflammasomes after surgery

Intranuclear delivery of the transcription modulation domain of Tbet-improved lupus nephritis in (NZB/NZW) F1 lupus-prone mice

Intranuclear interactomic inhibition of FoxP3 suppresses functions of Treg cells.

Intranuclear interactomic inhibition of NF-κB suppresses LPS-induced severe sepsis.

Mesenchymal stem cells pretreated with delivered Hph-1-Hsp70 protein are protected from hypoxia-mediated cell death and rescue heart functions from myocardial injury.

Mitochondrial ATP synthase is a target for TNBS-induced protein carbonylation in XS-106 dendritic cells

Monitoring the status of T-cell activation in a microfluidic system

PLCδ1 protein rescues ischemia-reperfused heart by the regulation of calcium homeostasis

Qualitative and quantitative differences in the intensity of Fas-mediated intracellular signals determine life and death in T cells

Qualitatively differential regulation of T cell activation and apoptosis by T cell receptor zeta chain ITAMs and their tyrosine residues.

Quantification of cellular uptake and in vivo tracking of transduction using real-time monitoring

RORγt-specific transcriptional interactomic inhibition suppresses autoimmunity associated with TH17 cells

Regulatory T Cells in Tumor Microenvironment and Approach for Anticancer Immunotherapy

Skin-penetrating methotrexate alleviates imiquimod-induced psoriasiform dermatitis via decreasing IL-17-producing gamma delta T cells

Synergistic inhibition of T-cell activation by a cell-permeable ZAP-70 mutant and ctCTLA-4.

T Cell-specific immunosuppression using tautomycetin or PTD-conjugated protein drugs

Tautomycetin inhibits growth of colorectal cancer cells through p21cip/WAF1 induction via the extracellular signal-regulated kinase pathway

The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils

The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells

The synergistic effect of Tautomycetin on Cyclosporine A-mediated immunosuppression in a rodent islet allograft model

Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein

Transducible form of p47phox and p67phox compensate for defective NADPH oxidase activity in neutrophils of patients with chronic granulomatous disease.

Transduction of the cytoplasmic domain of CTLA-4 inhibits TcR-specific activation signals and prevents collagen-induced arthritis

Trichomonas vaginalis inhibits proinflammatory cytokine production in macrophages by suppressing NF-kappaB activation.

dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis