List of works by Wah Chiu

3D RNA-scaffolded wireframe origami

scientific article published in 2023

3D volume reconstruction of a mouse brain from histological sections using warp filtering

scientific article published on 3 April 2006

4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement

scientific article

4.4 Å cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus

scientific article

A 3.4-Å cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles

scientific article published on 11 August 2020

A 9 angstroms single particle reconstruction from CCD captured images on a 200 kV electron cryomicroscope

scientific article published in August 2004

A Uniique Density at the Portal Vertex of HSV Virions Revealed by Asymmetric Averaging of Subtomograms

A Unique BSL-3 Cryo-Electron Microscopy Laboratory at UTMB.

scientific article

A chikungunya fever vaccine utilizing an insect-specific virus platform

scientific article (publication date: 19 December 2016)

A digital atlas to characterize the mouse brain transcriptome

scientific article

A geometric database for gene expression data

scientific article

A glycoprotein B-neutralizing antibody structure at 2.8 Å uncovers a critical domain for herpesvirus fusion initiation

scientific article published on 18 August 2020

A newly isolated reovirus has the simplest genomic and structural organization of any reovirus

scientific article

A single immunization with spike-functionalized ferritin vaccines elicits neutralizing antibody responses against SARS-CoV-2 in mice

scientific article published on 28 August 2020

A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions

scientific article (publication date: 2012)

Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density

scientific article

Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures

scientific article published on 02 July 2020

Achievable resolution from images of biological specimens acquired from a 4k x 4k CCD camera in a 300-kV electron cryomicroscope

scientific article

Alignment algorithms and per-particle CTF correction for single particle cryo-electron tomography

scientific article

An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions

scientific article

An atomic model of brome mosaic virus using direct electron detection and real-space optimization

scientific article

An expanded conformation of single-ring GroEL-GroES complex encapsulates an 86 kDa substrate.

scientific article

Applications of a bilateral denoising filter in biological electron microscopy

scientific article

Architecture of the herpes simplex virus major capsid protein derived from structural bioinformatics

scientific article published in August 2003

Assessing the capabilities of a 4kx4k CCD camera for electron cryo-microscopy at 300kV.

scientific article

Automated pipeline for atlas-based annotation of gene expression patterns: application to postnatal day 7 mouse brain

scientific article

Automated segmentation of molecular subunits in electron cryomicroscopy density maps.

scientific article published on 14 June 2006

Automated specimen search in cryo-TEM observation with DIFF-defocus imaging

scientific article

Averaging tens to hundreds of icosahedral particle images to resolve protein secondary structure elements using a Multi-Path Simulated Annealing optimization algorithm

scientific article published on 6 July 2007

Backbone structure of the infectious epsilon15 virus capsid revealed by electron cryomicroscopy

scientific article

Bilamellar cationic liposomes protect adenovectors from preexisting humoral immune responses

scientific article

CTF Challenge: Result summary.

scientific article published on 23 April 2015

Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions

scientific article

Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions

scientific article published on June 2016

Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor

scientific article

Coat protein fold and maturation transition of bacteriophage P22 seen at subnanometer resolutions

scientific article published in February 2003

Common ancestry of herpesviruses and tailed DNA bacteriophages

scientific article

Comparison of Segger and other methods for segmentation and rigid-body docking of molecular components in cryo-EM density maps

scientific article

Computing a family of skeletons of volumetric models for shape description

scientific article published on May 2007

Conformational changes in Sindbis virions resulting from exposure to low pH and interactions with cells suggest that cell penetration may occur at the cell surface in the absence of membrane fusion

scientific article published on July 2004

Constructing and validating initial Cα models from subnanometer resolution density maps with pathwalking

scientific article published in March 2012

Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis

scientific article

Controllable Self-Assembly of RNA Tetrahedrons with Precise Shape and Size for Cancer Targeting

scientific article published on 20 June 2016

Convolutional neural networks for automated annotation of cellular cryo-electron tomograms

scientific article published on 28 August 2017

Corrigendum: Protruding knob-like proteins violate local symmetries in an icosahedral marine virus

scientific article published on 12 January 2015

Cryo-EM Structure of a Molluscan Hemocyanin Suggests Its Allosteric Mechanism

scientific article

Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of Vo complex

scientific article published on 07 October 2020

Cryo-EM asymmetric reconstruction of bacteriophage P22 reveals organization of its DNA packaging and infecting machinery

scientific article published on 25 May 2006

Cryo-EM model validation recommendations based on outcomes of the 2019 EMDataResource challenge

scientific article published on 04 February 2021

Cryo-EM model validation using independent map reconstructions

scientific article

Cryo-EM of macromolecular assemblies at near-atomic resolution

scientific article

Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure

scientific article

Cryo-EM structures of vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution

scientific article published on 20 March 2019

Cryo-EM techniques to resolve the structure of HSV-1 capsid-associated components

scientific article

Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome

scientific article published on 20 July 2020

Cryo-electron microscopy targets in CASP13: Overview and evaluation of results

scientific article published on 23 October 2019

CryoEM reveals the stochastic nature of individual ATP binding events in a group II chaperonin

scientific article published on 06 August 2021

Cryoelectron microscopy of icosahedral virus particles

scientific article

Cryoelectron microscopy of protein IX-modified adenoviruses suggests a new position for the C terminus of protein IX.

scientific article

Cryogenic single-molecule fluorescence annotations for electron tomography reveal in situ organization of key proteins in Caulobacter

scientific article published on 08 June 2020

Crystal structure of a nematode-infecting virus

scientific article

Crystallographic Conformers of Actin in a Biologically Active Bundle of Filaments

scientific article

DNA packaging and delivery machines in tailed bacteriophages

scientific article published on 28 March 2007

De novo backbone trace of GroEL from single particle electron cryomicroscopy

scientific article

Deriving folds of macromolecular complexes through electron cryomicroscopy and bioinformatics approaches

scientific article

Designer nanoscale DNA assemblies programmed from the top down

scientific article

Determination of icosahedral virus structures by electron cryomicroscopy at subnanometer resolution

scientific article

Direct electron detection yields cryo-EM reconstructions at resolutions beyond 3/4 Nyquist frequency

scientific article

Discrete structure of an RNA folding intermediate revealed by cryo-electron microscopy

scientific article

Distribution of evaluation scores for the models submitted to the second cryo-EM model challenge

article by Andriy Kryshtafovych et al published October 2018 in Data in Brief

Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber

scientific article

EMDataBank unified data resource for 3DEM.

scientific article

EMDataBank.org: unified data resource for CryoEM

scientific article

EMEN2: an object oriented database and electronic lab notebook

scientific article

Editorial overview: Cryo Electron Microscopy: Exciting advances in CryoEM Herald a new era in structural biology.

scientific article published on 8 August 2017

Editorial overview: virus structure and function

scientific article

Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly.

scientific article published in February 2018

Electron Cryomicroscopy of Viruses at Near-Atomic Resolutions

scientific article

Electron cryo-microscopy of VAT, the archaeal p97/CDC48 homologue from Thermoplasma acidophilum

scientific article published on April 2002

Electron cryomicroscopy of biological machines at subnanometer resolution

scientific article

Electron cryotomography reveals the portal in the herpesvirus capsid

scientific article published on 6 December 2006

Electron cryotomography reveals ultrastructure alterations in platelets from patients with ovarian cancer

scientific article

Emdatabank: Unified Data Resource for 3DEM

Erratum: Structural diversity of supercoiled DNA

scientific article published in Nature Communications

Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins

scientific article published on 29 April 2007

Evolving data standards for cryo-EM structures

scientific article published on 24 January 2020

Experimental verification of conformational variation of human fatty acid synthase as predicted by normal mode analysis

scientific article published in February 2004

Fabrication of RNA 3D Nanoprisms for Loading and Protection of Small RNAs and Model Drugs

scientific article published on 19 October 2016

Fast rotational matching of single-particle images.

scientific article published on 30 September 2005

Filamentous, mixed micelles of triblock copolymers enhance tumor localization of indocyanine green in a murine xenograft model

scientific article published on 12 December 2011

Flexible architecture of IP3R1 by Cryo-EM

scientific article

Focal pair merging for contrast enhancement of single particles.

scientific article published in October 2003

Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer

scientific article published on 30 September 2020

Gating machinery of InsP3R channels revealed by electron cryomicroscopy

scientific article published on 12 October 2015

Genome sequence, structural proteins, and capsid organization of the cyanophage Syn5: a "horned" bacteriophage of marine synechococcus

scientific article

Gorgon and pathwalking: macromolecular modeling tools for subnanometer resolution density maps

scientific article

High resolution structural studies of complex icosahedral viruses: a brief overview

scientific article

Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers

scientific article published on 23 April 2013

Identification of secondary structure elements in intermediate-resolution density maps

scientific article published on January 2007

Identifying the assembly pathway of cyanophage inside the marine bacterium using electron cryo-tomography.

scientific article

Improved Peak Detection and Deconvolution of Native Electrospray Mass Spectra from Large Protein Complexes

scientific article published on September 2015

Influence of DNA sequence on the structure of minicircles under torsional stress

scientific article published on 13 June 2017

Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM

scientific article published on 13 March 2020

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses

scientific article

Interprotofilament interactions between Alzheimer's Abeta1-42 peptides in amyloid fibrils revealed by cryoEM

scientific article

JADAS: a customizable automated data acquisition system and its application to ice-embedded single particles

scientific article

Learning-based segmentation framework for tissue images containing gene expression data

scientific article

Lemon-shaped halo archaeal virus His1 with uniform tail but variable capsid structure

scientific article

Location and flexibility of the unique C-terminal tail of Aquifex aeolicus co-chaperonin protein 10 as derived by cryo-electron microscopy and biophysical techniques

scientific article published on 17 June 2008

MOTIF-EM: an automated computational tool for identifying conserved regions in CryoEM structures

scientific article

Machining protein microcrystals for structure determination by electron diffraction

article published in the Proceedings of the National Academy of Sciences of the United States of America

Measurement of atom resolvability in cryo-EM maps with Q-scores

scientific article published on 10 February 2020

Mechanism of folding chamber closure in a group II chaperonin

scientific article

Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT

scientific article published on 8 June 2008

Mitochondrial ATP synthasome. Cristae-enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP.

scientific article published on 30 January 2003

Mitochondrial ATP synthasome: three-dimensional structure by electron microscopy of the ATP synthase in complex formation with carriers for Pi and ADP/ATP.

scientific article published on 27 May 2004

Model of human low-density lipoprotein and bound receptor based on cryoEM

scientific article

Modeling protein structure at near atomic resolutions with Gorgon

scientific article

Modular software platform for low-dose electron microscopy and tomography

scientific article

Modulation of STAT3 folding and function by TRiC/CCT chaperonin

scientific article

Multifunctional RNA nanoparticles

scientific article

Multiple Functional Roles of the Accessory I-Domain of Bacteriophage P22 Coat Protein Revealed by NMR Structure and CryoEM Modeling

scientific article

Near-atomic-resolution cryo-EM for molecular virology

scientific article

Neutralizing Antibodies Inhibit Chikungunya Virus Budding at the Plasma Membrane

scholarly article published by Scott C. Weaver in 2018

Object oriented database and electronic notebook for transmission electron microscopy

scientific article published on December 2003

Opportunities for Cryogenic Electron Microscopy in Materials Science and Nanoscience

scientific article published on 28 July 2020

Outcome of a workshop on archiving structural models of biological macromolecules

scientific article

Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop

scientific article published on 18 June 2015

Outcome of the first electron microscopy validation task force meeting

scientific article (publication date: 8 February 2012)

Partially polymerized liposomes: stable against leakage yet capable of instantaneous release for remote controlled drug delivery

scientific article

Practical performance evaluation of a 10k × 10k CCD for electron cryo-microscopy

scientific article

Programmable Supra-Assembly of a DNA Surface Adapter for Tunable Chiral Directional Self-Assembly of Gold Nanorods

scientific article

Protein structure fitting and refinement guided by cryo-EM density

scientific article

Protruding knob-like proteins violate local symmetries in an icosahedral marine virus

scientific article

Publisher Correction: A glycoprotein B-neutralizing antibody structure at 2.8 Å uncovers a critical domain for herpesvirus fusion initiation

scientific article published on 28 August 2020

Purification of AcrAB-TolC Multidrug Efflux Pump for Cryo-EM Analysis

scientific article published in January 2018

Quantifying Variability of Manual Annotation in Cryo-Electron Tomograms

scientific article

Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions

scientific article published on 23 March 2010

Quaternary structure of human fatty acid synthase by electron cryomicroscopy

scientific article

REMBI: Recommended Metadata for Biological Images—enabling reuse of microscopy data in biology

scientific article published on 21 May 2021

Radiation damage effects at four specimen temperatures from 4 to 100 K.

scientific article

Reconstructing virus structures from nanometer to near-atomic resolutions with cryo-electron microscopy and tomography

scientific article published on January 2012

Refinement of protein structures by iterative comparative modeling and CryoEM density fitting

scientific article

Refinement of protein structures into low-resolution density maps using rosetta

scientific article published on 08 July 2009

Remotely triggered liposome release by near-infrared light absorption via hollow gold nanoshells

scientific article

Reprogramming an ATP-driven protein machine into a light-gated nanocage

scientific article (publication date: December 2013)

Resolution and Probabilistic Models of Components in CryoEM Maps of Mature P22 Bacteriophage

scientific article published on 29 December 2015

Responses to `Atomic resolution': a badly abused term in structural biology.

scientific article

Seeing GroEL at 6 A resolution by single particle electron cryomicroscopy

scientific article published on July 2004

Seeing the Portal in Membrane-containing Bacteriophage PRD1 by Cryo-EM

scholarly article by Chuan Hong et al published August 2014 in Microscopy and Microanalysis

Single-particle electron cryomicroscopy of the ion channels in the excitation-contraction coupling junction

scientific article published on January 2007

Structural analysis of the anaphase-promoting complex reveals multiple active sites and insights into polyubiquitylation

scientific article published on December 2005

Structural and Functional Impacts of ER Coactivator Sequential Recruitment

scientific article published on 23 August 2017

Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus

scientific article

Structural biology of cellular machines

scientific article

Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus

scientific article

Structural characterization of components of protein assemblies by comparative modeling and electron cryo-microscopy.

scientific article

Structural diversity of supercoiled DNA. ⬇️

scientific article

Structural mechanism of SDS-induced enzyme activity of scorpion hemocyanin revealed by electron cryomicroscopy

scientific article

Structure of Ca2+ release channel at 14 A resolution

scientific article

Structure of Halothiobacillus neapolitanus carboxysomes by cryo-electron tomography

scientific article

Structure of Trypanosoma brucei flagellum accounts for its bihelical motion

scientific article

Structure of a Conserved Retroviral RNA Packaging Element by NMR Spectroscopy and Cryo-Electron Tomography ⬇️

scientific article published on October 8, 2010

Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus

scientific article

Structure of isolated nucleocapsids from venezuelan equine encephalitis virus and implications for assembly and disassembly of enveloped virus

scientific article

Structure of the 30 kDa HIV-1 RNA Dimerization Signal by a Hybrid Cryo-EM, NMR, and Molecular Dynamics Approach

scientific article published in February 2018

Structure of the AcrAB–TolC multidrug efflux pump

scientific article

Structure of the bifunctional and Golgi-associated formiminotransferase cyclodeaminase octamer

scientific article published on 22 July 2004

Structure of the herpesvirus major capsid protein

scientific article (publication date: 17 February 2003)

Structure of the type 1 inositol 1,4,5-trisphosphate receptor revealed by electron cryomicroscopy

scientific article published on 24 April 2003

Structure of triglyceride-rich human low-density lipoproteins according to cryoelectron microscopy

scientific article published in December 2003

Studying large viruses

scientific article

SuRVoS: Super-Region Volume Segmentation workbench

scientific article

Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel

scientific article

Subunit conformational variation within individual GroEL oligomers resolved by Cryo-EM.

scientific article published on 14 July 2017

Supramolecular non-amyloid intermediates in the early stages of α-synuclein aggregation

scientific article published on 6 March 2012

Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle

scientific article

TRiC's tricks inhibit huntingtin aggregation

scientific article published on 09 July 2013

The 2010 cryo-EM modeling challenge

scientific article published in September 2012

The 3.5-Å CryoEM Structure of Nanodisc-Reconstituted Yeast Vacuolar ATPase Vo Proton Channel.

scientific article published on 7 March 2018

The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion

scientific article published on 07 January 2021

The Structure of Barmah Forest Virus as Revealed by Cryo-Electron Microscopy at a 6-Angstrom Resolution Has Detailed Transmembrane Protein Architecture and Interactions

scientific article

The group II chaperonin Mm-Cpn binds and refolds human γD crystallin

scientific article published on January 2011

The molecular architecture of the eukaryotic chaperonin TRiC/CCT

scientific article

The pore structure of the closed RyR1 channel

scientific article

The skeletal muscle Ca2+ release channel has an oxidoreductase-like domain

scientific article

The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state

scientific article

Three-Dimensional Analysis of Particle Distribution on Filter Layers inside N95 Respirators by Deep Learning

scientific article published on 07 December 2020

Tracing conformational changes in proteins

scientific article

Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy

scientific article published on 20 February 2020

Validated near-atomic resolution structure of bacteriophage epsilon15 derived from cryo-EM and modeling

scientific article

Validation of cryo-EM structure of IP₃R1 channel

scientific article published on 23 May 2013

Virus structure. Preface

scientific article published in January 2003

Visualizing Adsorption of Cyanophage P-SSP7 onto Marine Prochlorococcus

scientific article

Visualizing red blood cell sickling and the effects of inhibition of sphingosine kinase 1 using soft X-ray tomography

scientific article

Visualizing the structural changes of bacteriophage Epsilon15 and its Salmonella host during infection

scientific article

Visualizing virus assembly intermediates inside marine cyanobacteria

scientific article

Web-based Simulation for Contrast Transfer Function and Envelope Functions

scientific article

Workshop on molecular animation

scientific article

Zernike phase contrast cryo-electron microscopy and tomography for structure determination at nanometer and subnanometer resolutions

scientific article

Zernike phase-contrast electron cryotomography applied to marine cyanobacteria infected with cyanophages

scientific article

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