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List of works by Gordon Dougan

A Biohistorical Perspective of Typhoid and Antimicrobial Resistance

scientific article published on 01 October 2019

A GC1 Acinetobacter baumannii isolate carrying AbaR3 and the aminoglycoside resistance transposon TnaphA6 in a conjugative plasmid.

scientific article

A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection

scientific article published on 08 October 2019

A Phylogenetic and Phenotypic Analysis of Salmonella enterica Serovar Weltevreden, an Emerging Agent of Diarrheal Disease in Tropical Regions

scientific article published on 11 February 2016

A Salmonella Typhimurium-Typhi genomic chimera: a model to study Vi polysaccharide capsule function in vivo

scientific article

A TNF region haplotype offers protection from typhoid fever in Vietnamese patients

scientific article published on 15 May 2007

A blueprint for the implementation of a validated approach for the detection of SARS-Cov2 in clinical samples in academic facilities

scientific article published on 17 April 2020

A blueprint for the implementation of a validated approach for the detection of SARS-Cov2 in clinical samples in academic facilities

scientific article published on 01 June 2020

A clinical, microbiological, and pathological study of intestinal perforation associated with typhoid fever

scientific article published on 14 June 2004

A conserved acetyl esterase domain targets diverse bacteriophages to the Vi capsular receptor of Salmonella enterica serovar Typhi

scientific article published on 3 September 2010

A generalized transducing phage for the murine pathogen Citrobacter rodentium

scientific article published in September 2007

A genomewide mutagenesis screen identifies multiple genes contributing to Vi capsular expression in Salmonella enterica serovar Typhi.

scientific article published on 11 January 2013

A linear plasmid truncation induces unidirectional flagellar phase change in H:z66 positive Salmonella Typhi.

scientific article

A new era in the genomics of bacteria

A novel ciprofloxacin-resistant subclade of H58 Salmonella Typhi is associated with fluoroquinolone treatment failure

scientific article published on 11 March 2016

A novel linear plasmid mediates flagellar variation in Salmonella Typhi

scientific article

A novel therapeutic antibody screening method using bacterial high-content imaging reveals functional antibody binding phenotypes of Escherichia coli ST131

scientific article published on 24 July 2020

A randomised trial evaluating the safety and immunogenicity of the novel single oral dose typhoid vaccine M01ZH09 in healthy Vietnamese children

scientific article

A simple method for directional transcriptome sequencing using Illumina technology

scientific article

A strand-specific RNA-Seq analysis of the transcriptome of the typhoid bacillus Salmonella typhi

scientific article

A study on the geophylogeny of clinical and environmental Vibrio cholerae in Kenya.

scientific article

ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex

scientific article published in October 2016

Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge model

scientific article published on 22 May 2015

Adaptation of host transmission cycle during Clostridium difficile speciation

scientific article published on 12 August 2019

Advances in Understanding Bacterial Pathogenesis Gained from Whole-Genome Sequencing and Phylogenetics

scientific article published on May 2016

Allele variants of enterotoxigenic Escherichia coli heat-labile toxin are globally transmitted and associated with colonization factors.

scientific article

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity

An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation

scientific article published on 19 September 2019

An O antigen capsule modulates bacterial pathogenesis in Shigella sonnei

scientific article

An evaluation of purified Salmonella Typhi protein antigens for the serological diagnosis of acute typhoid fever

scientific article published on 24 May 2017

An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid

scientific article published on 05 October 2016

An iPSC-Derived Myeloid Lineage Model of Herpes Virus Latency and Reactivation

scientific article published on 09 October 2019

An investigation into the Omp85 protein BamK in hypervirulent Klebsiella pneumoniae , and its role in outer membrane biogenesis

scientific article published on 19 September 2018

An investigation of clinical and immunological events following repeated aerodigestive tract challenge infections with live Mycobacterium bovis Bacille Calmette Guérin

scientific article published on 15 June 2010

An outpatient, ambulant-design, controlled human infection model using escalating doses of Salmonella Typhi challenge delivered in sodium bicarbonate solution

scientific article published on 10 February 2014

Analysis of the hypervariable region of the Salmonella enterica genome associated with tRNA(leuX).

scientific article published on April 2005

Antibacterial resistance in sub-Saharan Africa: an underestimated emergency

scientific article

Antibiotic Resistance and Typhoid

scientific article published on 01 March 2019

Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts

scientific article published on 29 June 2009

Antibodies to the Vi capsule of Salmonella Typhi in the serum of typhoid patients and healthy control subjects from a typhoid endemic region.

scientific article

Antibodies to the iron uptake ABC transporter lipoproteins PiaA and PiuA promote opsonophagocytosis of Streptococcus pneumoniae

scientific article

Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones

scientific article

Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

scientific article published on 27 May 2019

Author Correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

scientific article published on 1 August 2019

Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation and pathogen protection.

scientific article published on 23 January 2012

Binding of Plasmodium falciparum Merozoite Surface Proteins DBLMSP and DBLMSP2 to Human Immunoglobulin M Is Conserved among Broadly Diverged Sequence Variants

scientific article (publication date: July 2016)

Binding of intimin from enteropathogenic Escherichia coli to lymphocytes and its functional consequences

scientific article

Boosting of cellular immunity against Mycobacterium tuberculosis and modulation of skin cytokine responses in healthy human volunteers by Mycobacterium bovis BCG substrain Moreau Rio de Janeiro oral vaccine.

scientific article

Burden of enteric fever at three urban sites in Africa and Asia: a multicentre population-based study

scientific article published on 01 December 2021

C13orf31 (FAMIN) is a central regulator of immunometabolic function

scientific journal article

CD28 expression is required after T cell priming for helper T cell responses and protective immunity to infection.

scientific article

CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

scientific article

Cancer immunotherapy based on killing of Salmonella-infected tumor cells

scientific article published in May 2005

Candidate live, attenuated Salmonella enterica serotype Typhimurium vaccines with reduced fecal shedding are immunogenic and effective oral vaccines

scientific article published on 12 February 2007

Ceftriaxone-resistant Salmonella enterica serotype typhimurium sequence type 313 from Kenyan patients is associated with the blaCTX-M-15 gene on a novel IncHI2 plasmid.

scientific article published on 16 March 2015

Cell attachment properties and infectivity of host-adapted and environmentally adapted Citrobacter rodentium

scientific article

Central role for B lymphocytes and CD4+ T cells in immunity to infection by the attaching and effacing pathogen Citrobacter rodentium

scientific article published on September 2003

CesD2 of enteropathogenic Escherichia coli is a second chaperone for the type III secretion translocator protein EspD.

scientific article

ChIP-seq and transcriptome analysis of the OmpR regulon of Salmonella enterica serovars Typhi and Typhimurium reveals accessory genes implicated in host colonization.

scientific article published on 19 December 2012

Characterisation and distribution of a cryptic Salmonella typhi plasmid pHCM2.

scientific article published on May 2002

Characterisation of a live Salmonella vaccine stably expressing the Mycobacterium tuberculosis Ag85B-ESAT6 fusion protein

scientific article published on 13 September 2009

Characterisation of an acapsular mutant of Burkholderia pseudomallei identified by signature tagged mutagenesis

scientific article published on 01 July 2002

Characterization of Salmonella enterica derivatives harboring defined aroC and Salmonella pathogenicity island 2 type III secretion system (ssaV) mutations by immunization of healthy volunteers.

scientific article

Characterization of the genomes of a diverse collection of Salmonella enterica serovar Typhimurium definitive phage type 104

scientific article published on 10 October 2008

Characterization of the yehUT two-component regulatory system of Salmonella enterica Serovar Typhi and Typhimurium.

scientific article

Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance

scientific article published on 11 December 2018

Chronic bacterial infections: living with unwanted guests

scientific article

Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo

scientific article

Citrobacter rodentium is an unstable pathogen showing evidence of significant genomic flux

scientific article published in April 2011

Citrobacter rodentium of mice and man.

scientific article

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses

article

Combined high-resolution genotyping and geospatial analysis reveals modes of endemic urban typhoid fever transmission

scientific article published in October 2011

Combined immunodeficiency with severe inflammation and allergy caused by ARPC1B deficiency

scientific article published on 10 December 2016

Comparative genome analysis of Salmonella Enteritidis PT4 and Salmonella Gallinarum 287/91 provides insights into evolutionary and host adaptation pathways

scientific article

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

scientific article

Comparative whole genome sequence analysis of the carcinogenic bacterial model pathogen Helicobacter felis

scientific article

Comparison of Salmonella enterica serovars Typhi and Typhimurium reveals typhoidal-specific responses to bile

scientific article published on 11 December 2017

Complete Genome Sequence of Serotype III Streptococcus agalactiae Sequence Type 17 Strain 874391.

scientific article published on 19 October 2017

Complete Genome Sequences of Two Citrobacter rodentium Bacteriophages, CR8 and CR44b

scientific article

Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69.

scientific article published on 24 October 2008

Composition, acquisition, and distribution of the Vi exopolysaccharide-encoding Salmonella enterica pathogenicity island SPI-7.

scientific article

Conserved Features in the Structure, Mechanism, and Biogenesis of the Inverse Autotransporter Protein Family

scientific article

Constraints on lateral gene transfer in promoting fimbrial usher protein diversity and function

scientific article published in November 2017

Contrasting patterns of longitudinal population dynamics and antimicrobial resistance mechanisms in two priority bacterial pathogens over 7 years in a single center

scientific article published on 02 September 2019

Correction: Mcph1-Deficient Mice Reveal a Role for MCPH1 in Otitis Media.

scientific article

Correction: Multilocus Sequence Typing as a Replacement for Serotyping in Salmonella enterica

scientific article published on 21 October 2020

Correction: NK Cells Influence Both Innate and Adaptive Immune Responses after Mucosal Immunization with Antigen and Mucosal Adjuvant

scientific article published on 16 May 2018

Correction: Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa

scientific article published on 15 June 2015

Corrigendum: Five decades of genome evolution in the globally distributed, extensively antibiotic-resistant Acinetobacter baumannii global clone 1

scientific article published on 01 July 2019

Cytokine release by lipopolysaccharide-stimulated whole blood from patients with typhoid fever

scientific article published on 3 July 2002

DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development.

scientific article

Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections

scientific article published on 2 June 2015

Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model

scientific article

Derivation of Intestinal Organoids from Human Induced Pluripotent Stem Cells for Use as an Infection System.

scientific article published on 31 August 2016

Detecting SNPs and estimating allele frequencies in clonal bacterial populations by sequencing pooled DNA.

scientific article published on 3 June 2009

Detection of Vi-negative Salmonella enterica serovar typhi in the peripheral blood of patients with typhoid fever in the Faisalabad region of Pakistan.

scientific article

Detection of epidemic scarlet fever group A Streptococcus in Australia

article

Development of attenuated Salmonella strains that express heterologous antigens

scientific article published in January 2003

Diagnostic host gene signature for distinguishing enteric fever from other febrile diseases

scientific article published on 30 August 2019

Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen

scientific article published on 7 January 2016

Differential response of bovine monocyte-derived macrophages and dendritic cells to infection with Salmonella typhimurium in a low-dose model in vitro.

scientific article published in January 2003

Discovery and Characterization of Human-Urine Utilization by Asymptomatic-Bacteriuria-Causing Streptococcus agalactiae

scientific article

Discovery of trehalose phospholipids reveals functional convergence with mycobacteria

scientific article published on 25 February 2019

Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

scientific article published on 22 August 2016

Distinctive profiles of infection and pathology in hamsters infected with Clostridium difficile strains 630 and B1.

scientific article published on 14 September 2009

Distribution of the saa gene in strains of Shiga toxin-producing Escherichia coli of human and bovine origins

scientific article

Does the Trojan horse have an Achilles' heel?

scientific article published in January 2009

Draft Genome Sequence of Highly Nematicidal Bacillus thuringiensis DB27.

scientific article published on 20 February 2014

Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi.

scientific article published on November 2014

Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults

scientific article published on April 2010

Effective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19

scientific article published on 19 June 2020

Effects of chronic ascariasis and trichuriasis on cytokine production and gene expression in human blood: a cross-sectional study.

scientific article

Emergence and global spread of epidemic healthcare-associated Clostridium difficile

scientific article published on 9 December 2012

Emergence of NDM-producing Klebsiella pneumoniae and Escherichia coli in Spain: phylogeny, resistome, virulence and plasmids encoding blaNDM-like genes as determined by WGS

scientific article published in December 2019

Emergence of a 'hyperinfectious' bacterial state after passage of Citrobacter rodentium through the host gastrointestinal tract

article by Siouxsie Wiles et al published August 2005 in Cellular Microbiology

Emergence of a globally dominant IncHI1 plasmid type associated with multiple drug resistant typhoid

scientific article published in July 2011

Emergence of a new epidemic Neisseria meningitidis serogroup A Clone in the African meningitis belt: high-resolution picture of genomic changes that mediate immune evasion.

scientific article

Emergence of an Extensively Drug-Resistant Salmonella enterica Serovar Typhi Clone Harboring a Promiscuous Plasmid Encoding Resistance to Fluoroquinolones and Third-Generation Cephalosporins

scientific article published on 20 February 2018

Emergence of carbapenem, beta-lactamase inhibitor and cefoxitin resistant lineages from a background of ESBL-producing Klebsiella pneumoniae and K. quasipneumoniae highlights different evolutionary mechanisms

Emergence of dominant multidrug-resistant bacterial clades: Lessons from history and whole-genome sequencing

article published in the Proceedings of the National Academy of Sciences of the United States of America

Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host

scientific article published on 25 January 2016

Emergence of scarlet fever Streptococcus pyogenes emm12 clones in Hong Kong is associated with toxin acquisition and multidrug resistance

scientific article published on 17 November 2014

Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice

scientific article published on 21 December 2012

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

scientific article published on 9 November 2009

Epithelial IL-22RA1-mediated fucosylation promotes intestinal colonization resistance to an opportunistic pathogen

scientific article

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

scientific article published on 28 March 2017

Erratum: Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

scientific article published in March 2017

Evaluation of a novel Vi conjugate vaccine in a murine model of salmonellosis

scientific article published on 20 March 2006

Evidence for several waves of global transmission in the seventh cholera pandemic

scientific article

Evolution of atypical enteropathogenic E. coli by repeated acquisition of LEE pathogenicity island variants

scientific article

Evolutionary dynamics of Clostridium difficile over short and long time scales

scientific article published on 20 April 2010

Evolutionary history of Salmonella typhi

scientific article

Exclusive dependence of IL-10Rα signalling on intestinal microbiota homeostasis and control of whipworm infection

scientific article published on 14 January 2019

Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis

scientific article published on 25 April 2017

Expression of heterologous antigens in Salmonella Typhimurium vaccine vectors using the in vivo-inducible, SPI-2 promoter, ssaG.

scientific article published in September 2004

Expression of tetanus toxin Fragment C in tobacco chloroplasts

scientific article

Extensive diversity of Streptococcus pyogenes in a remote human population reflects global-scale transmission rather than localised diversification

scientific article

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

scientific article published on 01 February 2020

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

scientific article published on 01 January 2020

FBXO7 sensitivity of phenotypic traits elucidated by a hypomorphic allele

scientific article published on 06 March 2019

Factors associated with occurrence of salmonellosis among children living in Mukuru slum, an urban informal settlement in Kenya

scientific article published on 17 June 2020

Five decades of genome evolution in the globally distributed, extensively antibiotic-resistant Acinetobacter baumannii global clone 1.

scientific article published on 23 February 2016

Fluorescence-based phenotypic selection allows forward genetic screens in haploid human cells

scientific article

Functional analysis of Salmonella Typhi adaptation to survival in water

scientific article published on 01 November 2018

Functional cell permeable motifs within medically relevant proteins

scientific article published on February 2007

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism

scientific article

FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants

article

GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells.

scientific article published on 28 May 2015

GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump

scientific article published on 01 January 2019

Gallbladder carriage generates genetic variation and genome degradation in Salmonella Typhi

scientific article published on 21 October 2020

Genetic analysis of K88-mediated adhesion of enterotoxigenic Escherichia coli

scientific article published in Nature

Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens

scientific article published on 10 June 2016

Genetic variation associated with infection and the environment in the accidental pathogen Burkholderia pseudomallei

scientific article published on 22 November 2019

Genome Sequence of Porcine Escherichia coli Strain IMT8073, an Atypical Enteropathogenic E. coli Strain Isolated from a Piglet with Diarrhea.

scientific article published on August 2013

Genome and transcriptome adaptation accompanying emergence of the definitive type 2 host-restricted Salmonella enterica serovar Typhimurium pathovar

scientific article published on 27 August 2013

Genome sequencing of disease and carriage isolates of nontypeable Haemophilus influenzae identifies discrete population structure

scientific article published on 25 March 2014

Genome-Based Infection Tracking Reveals Dynamics of Clostridium difficile Transmission and Disease Recurrence

scientific article published on 18 December 2015

Genome-Wide Epigenetic and Transcriptomic Characterization of Human-Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids

scientific article published on 23 October 2018

Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes

scientific article

Genomic analysis on broiler-associated Clostridium perfringens strains and exploratory caecal microbiome investigation reveals key factors linked to poultry necrotic enteritis

scientific article published on 01 October 2019

Genomic and phenotypic variation in epidemic-spanning Salmonella enterica serovar Enteritidis isolates

scientific article

Genomic comparison of Salmonella enterica serovars and Salmonella bongori by use of an S. enterica serovar typhimurium DNA microarray

scientific article

Genomic epidemiology of Vibrio cholerae O1 associated with floods, Pakistan, 2010.

scientific article

Genomic history of the seventh pandemic of cholera in Africa.

scientific article published in November 2017

Genomics of the Argentinian cholera epidemic elucidate the contrasting dynamics of epidemic and endemic Vibrio cholerae

scientific article published on 01 October 2020

Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi

scientific article published on 27 July 2012

Global and regional dissemination and evolution of Burkholderia pseudomallei

scientific article published on 23 January 2017

Global dissemination of a multidrug resistant Escherichia coli clone

scientific article published on 31 March 2014

Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis

scientific article

Haploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligases

scientific article (publication date: 2013)

Helicobacter pylori has stimulatory effects on naive T cells

scientific article published in February 2006

High relatedness of invasive multi-drug resistant non-typhoidal Salmonella genotypes among patients and asymptomatic carriers in endemic informal settlements in Kenya

scientific article published on 03 August 2020

High-resolution genotyping of the endemic Salmonella Typhi population during a Vi (typhoid) vaccination trial in Kolkata.

scientific article

High-resolution single nucleotide polymorphism analysis distinguishes recrudescence and reinfection in recurrent invasive nontyphoidal Salmonella typhimurium disease

scientific article published on 7 February 2012

High-throughput bacterial SNP typing identifies distinct clusters of Salmonella Typhi causing typhoid in Nepalese children

scientific article published on 31 May 2010

High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease

scientific article

High-throughput genotyping of Salmonella enterica serovar Typhi allowing geographical assignment of haplotypes and pathotypes within an urban District of Jakarta, Indonesia

scientific article published on 5 March 2008

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation

scientific article published on 16 December 2019

High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi

scientific article published on 27 July 2008

Host defences to Citrobacter rodentium

scientific article

Host responses to melioidosis and tuberculosis are both dominated by interferon-mediated signaling

scientific article

Host/pathogen interactions at mucosal surfaces: immune consequences

scientific article

How Can the Typhoid Fever Surveillance in Africa and the Severe Typhoid Fever in Africa Programs Contribute to the Introduction of Typhoid Conjugate Vaccines?

scientific article published on 01 October 2019

How bacteria and their products provide clues to vaccine and adjuvant development

scientific article published on April 2006

Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2.

scientific article published on 05 June 2017

IFITM3 restricts the morbidity and mortality associated with influenza

scientific article

IRF5 promotes influenza-induced inflammatory responses in human iPSC-derived myeloid cells and murine models

scientific article published on 19 February 2020

Identification and characterization of the novel colonization factor CS30 based on whole genome sequencing in enterotoxigenic Escherichia coli (ETEC).

scientific article published on 2 October 2017

Identification of Salmonella enterica serovar Typhi genotypes by use of rapid multiplex ligation-dependent probe amplification

scientific article (publication date: September 2013)

Identification of a Novel Citrobacter rodentium Type III Secreted Protein, EspI, and Roles of This and Other Secreted Proteins in Infection

scientific article published in July 2007

Identification of a marker for two lineages within the GC1 clone of Acinetobacter baumannii

scientific article published on 29 September 2013

Identification of a novel Citrobacter rodentium type III secreted protein, EspI, and roles of this and other secreted proteins in infection

scientific article published on April 2004

Identification of a novel type IV pilus gene cluster required for gastrointestinal colonization of Citrobacter rodentium

scientific article

Identification of core and variable components of the Salmonella enterica subspecies I genome by microarray.

scientific article published on December 2005

Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global distribution

scientific article

Identification of novel adenovirus genotype 90 in children from Bangladesh

scientific article published on 24 September 2018

Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli

scientific article

Immunity to salmonellosis

scientific article published on March 2011

Immunization Against Bordetella pertussis Infection of Mice Using a Salmonella typhimurium aro Vaccine Strain Expressing the Bordetella pertussis P.69 Antigen

Immunization with the iron uptake ABC transporter proteins PiaA and PiuA prevents respiratory infection with Streptococcus pneumoniae

scientific article published on 02 May 2006

Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice

scientific article published on 01 October 2004

Impaired resistance and enhanced pathology during infection with a noninvasive, attaching-effacing enteric bacterial pathogen, Citrobacter rodentium, in mice lacking IL-12 or IFN-gamma

scientific article published on 01 February 2002

In vivo regulation of the Vi antigen in Salmonella and induction of immune responses with an in vivo-inducible promoter

scientific article

Increased susceptibility of C1q-deficient mice to Salmonella enterica serovar Typhimurium infection

scientific article published on February 2002

Induced pluripotent stem cell derived macrophages as a cellular system to study salmonella and other pathogens

scientific article published on 6 May 2015

Induction of Cell Cycle and NK Cell Responses by Live-Attenuated Oral Vaccines against Typhoid Fever

scientific article published on 12 October 2017

Infection Susceptibility in Gastric Intrinsic Factor (Vitamin B12)-Defective Mice Is Subject to Maternal Influences

scientific article published on 21 June 2016

Insertions in the OCL1 locus of Acinetobacter baumannii lead to shortened lipooligosaccharides

scientific article

Integrated view of Vibrio cholerae in the Americas

scientific article

Interaction of Salmonella Typhimurium with Dendritic Cells Derived from Pluripotent Embryonic Stem Cells

scientific article published on December 28, 2012

Interaction of Salmonella enterica Serovar Typhimurium with Intestinal Organoids Derived from Human Induced Pluripotent Stem Cells.

scientific article

Interaction of Salmonella enterica serovar Typhi with cultured epithelial cells: roles of surface structures in adhesion and invasion

scientific article published on July 2008

Interaction of Salmonella enterica with basil and other salad leaves

scientific article published on 2 October 2008

Interaction of enteric bacterial pathogens with murine embryonic stem cells

scientific article

Interferon-driven alterations of the host's amino acid metabolism in the pathogenesis of typhoid fever

scientific article published on 23 May 2016

Interleukin-22 promotes phagolysosomal fusion to induce protection against Typhimurium in human epithelial cells

article published in the Proceedings of the National Academy of Sciences of the United States of America

Intra- and interhost evolutionary dynamics of equine influenza virus

scientific article

Intracellular adhesion molecule 1 plays a key role in acquired immunity to salmonellosis

scientific article

Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa

scientific article

Invasive Group A Streptococcus Infection among Children, Rural Kenya

scientific article published on February 2016

Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa.

scientific article

Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model

scientific article published on 03 July 2019

Laboratory and Molecular Surveillance of Paediatric Typhoidal Salmonella in Nepal: Antimicrobial Resistance and Implications for Vaccine Policy

scholarly article published 18 January 2018

Laboratory and molecular surveillance of paediatric typhoidal Salmonella in Nepal: Antimicrobial resistance and implications for vaccine policy

scientific article published on 23 April 2018

Legionella pneumophila strain 130b possesses a unique combination of type IV secretion systems and novel Dot/Icm secretion system effector proteins

scientific article

Live Salmonella enterica serovar Typhimurium (S. Typhimurium) elicit dendritic cell responses that differ from those induced by killed S. Typhimurium

scientific article

Live bacteria as the basis for immunotherapies against cancer.

scientific article

Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2

scientific article published on 01 February 2020

Make it new: reformism and British public health

scientific article published on 03 September 2020

Mannosidase 2, alpha 1 deficiency is associated with ricin resistance in embryonic stem (ES) cells

scientific article

Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome

scientific article

Mcph1-deficient mice reveal a role for MCPH1 in otitis media

scientific journal article

Meeting the discovery challenge of drug-resistant infections: progress and focusing resources

scientific article published on 23 November 2018

Microevolution of Monophasic Salmonella Typhimurium during Epidemic, United Kingdom, 2005-2010.

scientific article published on April 2016

Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions.

scientific article published on 27 October 2016

Mobilization of the incQ plasmid R300B with a chromosomal conjugation system in Salmonella enterica serovar typhi

scientific article published on 04 April 2008

Modulation of dendritic cell endocytosis and antigen processing pathways by Escherichia coli heat-labile enterotoxin and mutant derivatives

scientific article published on 01 March 2003

Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa

scientific article published on 22 September 2016

Molecular analysis of incHI1 antimicrobial resistance plasmids from Salmonella serovar Typhi strains associated with typhoid fever

scientific article published on September 2003

Molecular and phenotypic analysis of the CS54 island of Salmonella enterica serotype typhimurium: identification of intestinal colonization and persistence determinants

scientific article

Molecular and physiological analysis of three Pseudomonas aeruginosa phages belonging to the "N4-like viruses".

scientific article

Molecular characterization of the 2011 Hong Kong scarlet fever outbreak

scientific article

Molecular characterization of the Salmonella enterica serovar Typhi Vi-typing bacteriophage E1.

scientific article

Molecular characterization of the viaB locus encoding the biosynthetic machinery for Vi capsule formation in Salmonella Typhi

scientific article

Molecular epidemiology and intercontinental spread of cholera

scientific article published on 22 July 2019

More than 18,000 effectors in the genus genome provide multiple, independent combinations for replication in human cells

article published in the Proceedings of the National Academy of Sciences of the United States of America

Mucosal immunisation of murine neonates using whole cell and acellular Pertussis vaccines.

scientific article

Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin

scientific article

Multidrug-resistant Nontyphoidal Salmonella Hotspots as Targets for Vaccine Use in Management of Infections in Endemic Settings

scientific article published in 2019

Multidrug-resistant Salmonella enterica serotype Typhi, Gulf of Guinea Region, Africa.

scientific article

Multidrug-resistant Salmonella enterica serovar paratyphi A harbors IncHI1 plasmids similar to those found in serovar typhi.

scientific article published on 23 March 2007

Multilocus sequence typing analysis of Shigella flexneri isolates collected in Asian countries

scientific article

Multilocus sequence typing as a replacement for serotyping in Salmonella enterica

scientific article published in 2012

Multiple Introductions of Salmonella enterica Serovar Typhi H58 with Reduced Fluoroquinolone Susceptibility into Chile

scientific article published on 01 November 2020

Mutagenesis of conserved tryptophan residues within the receptor-binding domain of intimin: influence on binding activity and virulence

scientific article published on March 2002

NBEAL2 is required for neutrophil and NK cell function and pathogen defense

scientific article published on 7 August 2017

NK cells influence both innate and adaptive immune responses after mucosal immunization with antigen and mucosal adjuvant.

scientific article

Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV.

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New Variant of Multidrug-Resistant Serovar Typhimurium Associated with Invasive Disease in Immunocompromised Patients in Vietnam

scholarly article by Alison E Mather et al published 4 September 2018 in mBio

New advances in the production of edible plant vaccines: chloroplast expression of a tetanus vaccine antigen, TetC.

scientific article published on April 2004

Non-clinical safety evaluation of novel vaccines and adjuvants: new products, new strategies

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Non-typhoidal Salmonella Typhimurium ST313 isolates that cause bacteremia in humans stimulate less inflammasome activation than ST19 isolates associated with gastroenteritis

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OX40 ligation on activated T cells enhances the control of Cryptococcus neoformans and reduces pulmonary eosinophilia

scientific article published on 01 June 2003

Optimization of Salmonella enterica serovar typhi DeltaaroC DeltassaV derivatives as vehicles for delivering heterologous antigens by chromosomal integration and in vivo inducible promoters

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Oral Wild-Type Salmonella Typhi Challenge Induces Activation of Circulating Monocytes and Dendritic Cells in Individuals Who Develop Typhoid Disease

scientific article published on 11 June 2015

Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium

scientific article published in October 2004

Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis.

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Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector

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Pathogen genomic surveillance of typhoidal Salmonella infection in adults and children reveals no association between clinical outcomes and infecting genotypes

scientific article published on 13 July 2020

Patterns of genome evolution that have accompanied host adaptation in Salmonella

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Persistent circulation of a fluoroquinolone-resistant Salmonella enterica Typhi clone in the Indian subcontinent

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Phylogenetic Analysis Indicates a Longer Term Presence of the Globally Distributed H58 Haplotype of Salmonella Typhi in Southern India

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Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan

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Phylogenomic analysis of gastroenteritis-associated Clostridium perfringens in England and Wales over a 7-year period indicates distribution of clonal toxigenic strains in multiple outbreaks and extensive involvement of enterotoxin-encoding (CPE) pl

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Phylogeny, resistome and mobile genetic elements of emergent OXA-48 and OXA-245 Klebsiella pneumoniae clones circulating in Spain

scientific article published on 13 January 2016

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

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PlasmidTron: assembling the cause of phenotypes and genotypes from NGS data.

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PlasmidTron: assembling the cause of phenotypes from NGS data

Point of Care Nucleic Acid Testing for SARS-CoV-2 in Hospitalized Patients: A Clinical Validation Trial and Implementation Study

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Population structure and antimicrobial resistance patterns of Salmonella Typhi isolates in urban Dhaka, Bangladesh from 2004 to 2016

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Preterm Infant-Associated Clostridium tertium, Clostridium cadaveris, and Clostridium paraputrificum Strains: Genomic and Evolutionary Insights

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Probing local innate immune responses after mucosal immunisation

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Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes

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Prophage sequences defining hot spots of genome variation in Salmonella enterica serovar Typhimurium can be used to discriminate between field isolates

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Prospective Surveillance and Rapid Whole-Genome Sequencing Detects Two Unsuspected Outbreaks of Carbapenemase-Producing Klebsiella pneumoniae in a UK Teaching Hospital

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Protection against tetanus toxin using a plant-based vaccine

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Protection conferred by typhoid fever against recurrent typhoid fever in urban Kolkata

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Proteomic and genomic characterization of highly infectious Clostridium difficile 630 spores

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Pseudogene accumulation in the evolutionary histories of Salmonella enterica serovars Paratyphi A and Typhi

scientific article published on 21 January 2009

Public health value of next-generation DNA sequencing of enterohemorrhagic Escherichia coli isolates from an outbreak.

scientific article published on 7 November 2012

Public health. The cholera crisis in Africa

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Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses

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Publisher Correction: Identification and characterization of the novel colonization factor CS30 based on whole genome sequencing in enterotoxigenic Escherichia coli (ETEC).

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Quantitative proteomic analysis of Shigella flexneri and Shigella sonnei Generalized Modules for Membrane Antigens (GMMA) reveals highly pure preparations

scientific article published on 23 December 2015

Quorum sensing has an unexpected role in virulence in the model pathogen Citrobacter rodentium.

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RNA-seq reveals the RNA binding proteins, Hfq and RsmA, play various roles in virulence, antibiotic production and genomic flux in Serratia sp. ATCC 39006.

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Rapid emergence of multidrug resistant, H58-lineage Salmonella typhi in Blantyre, Malawi.

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Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study

scientific article published on 14 July 2020

Rapid implementation of real-time SARS-CoV-2 sequencing to investigate healthcare-associated COVID-19 infections

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Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive Salmonella Typhimurium ST313.

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Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak

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Reprogramming of T cells to natural killer-like cells upon Bcl11b deletion

scientific article published on 10 June 2010

Requirement of bic/microRNA-155 for normal immune function

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Resistance mechanisms and population structure of highly drug resistant Klebsiella in Pakistan during the introduction of the carbapenemase NDM-1

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Retrospective Analysis of Serotype Switching of Vibrio cholerae O1 in a Cholera Endemic Region Shows It Is a Non-random Process

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RocA truncation underpins hyper-encapsulation, carriage longevity and transmissibility of serotype M18 group A streptococci

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Role of sapA and yfgA in Susceptibility to Antibody-Mediated Complement-Dependent Killing and Virulence of Salmonella enterica Serovar Typhimurium.

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Routine use of microbial whole genome sequencing in diagnostic and public health microbiology

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Salmonella Typhi sense host neuroendocrine stress hormones and release the toxin haemolysin E

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Salmonella bongori provides insights into the evolution of the Salmonellae

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Salmonella enterica serovar Typhi Producing CTX-M-15 Extended Spectrum β-Lactamase in the Democratic Republic of the Congo

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Salmonella enterica serovar Typhi and the pathogenesis of typhoid fever

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Salmonella enterica serovar Typhimurium interaction with dendritic cells: impact of the sifA gene

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Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota

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Salmonella typhi and S typhimurium derivatives harbouring deletions in aromatic biosynthesis and Salmonella Pathogenicity Island-2 (SPI-2) genes as vaccines and vectors

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Salmonella typhi, the causative agent of typhoid fever, is approximately 50,000 years old.

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Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission

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Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission

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Searching for the elusive typhoid diagnostic

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Sequence-based analysis uncovers an abundance of non-coding RNA in the total transcriptome of Mycobacterium tuberculosis

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Sequencing and functional annotation of avian pathogenic Escherichia coli serogroup O78 strains reveal the evolution of E. coli lineages pathogenic for poultry via distinct mechanisms

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Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response.

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Shared genetic effects on chromatin and gene expression reveal widespread enhancer priming in immune response

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Shigella sonnei genome sequencing and phylogenetic analysis indicate recent global dissemination from Europe

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Signalling lymphocyte activation molecule family member 9 is found on select subsets of antigen-presenting cells and promotes resistance to Salmonella infection

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Signatures of adaptation in human invasive Salmonella Typhimurium ST313 populations from sub-Saharan Africa.

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Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants

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Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway

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Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection.

scientific article published on 10 May 2011

Structure, diversity, and mobility of the Salmonella pathogenicity island 7 family of integrative and conjugative elements within Enterobacteriaceae

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T cell fate and clonality inference from single-cell transcriptomes

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TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.

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Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice

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Targeting NLRP3 and staphylococcal pore-forming toxin receptors in human-induced pluripotent stem cell-derived macrophages

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Temporal fluctuation of multidrug resistant salmonella typhi haplotypes in the mekong river delta region of Vietnam

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Ten years experience of Salmonella infections in Cambridge, UK.

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Tenacious Endemic Typhoid Fever in Samoa

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The Citrobacter rodentium genome sequence reveals convergent evolution with human pathogenic Escherichia coli

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The Clostridium difficile spo0A Gene Is a Persistence and Transmission Factor

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The Hd, Hj, and Hz66 flagella variants of Salmonella enterica serovar Typhi modify host responses and cellular interactions

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The Molecular and Spatial Epidemiology of Typhoid Fever in Rural Cambodia

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The Role of Sphingosine-1-Phosphate Transporter Spns2 in Immune System Function

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The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys

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The T3SS effector EspT defines a new category of invasive enteropathogenic E. coli (EPEC) which form intracellular actin pedestals

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The Type III Secretion System Effector SptP of Salmonella enterica Serovar Typhi

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The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine effectiveness study designs: Accelerating the introduction of typhoid conjugate vaccines and reducing the global burden of enteric fever. Report from a meeting held on 26–27 October 2016,

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The agr locus regulates virulence and colonization genes in Clostridium difficile 027.

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The architecture and stabilisation of flagellotropic tailed bacteriophages

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The bacteriology of pouchitis: a molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing

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The burden and characteristics of enteric fever at a healthcare facility in a densely populated area of Kathmandu

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The capsular polysaccharide Vi from Salmonella typhi is a B1b antigen

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The classical lancefield antigen of group a Streptococcus is a virulence determinant with implications for vaccine design

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The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081.

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The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation

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The flagellotropic bacteriophage YSD1 targets Salmonella Typhi with a Chi-like protein tail fibre

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The genome of Salmonella enterica serovar Typhi

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The human transcriptome during nontyphoid Salmonella and HIV coinfection reveals attenuated NFkappaB-mediated inflammation and persistent cell cycle disruption

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The key role of genomics in modern vaccine and drug design for emerging infectious diseases

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The lrp gene and its role in type I fimbriation in Citrobacter rodentium.

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The microbiological and clinical characteristics of invasive salmonella in gallbladders from cholecystectomy patients in kathmandu, Nepal

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The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

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The neglected role of antibody in protection against bacteremia caused by nontyphoidal strains of Salmonella in African children

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The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa

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The population structure of Vibrio cholerae from the Chandigarh Region of Northern India

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The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response

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The role of prophage-like elements in the diversity of Salmonella enterica serovars

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The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development

scientific article published on 11 May 2015

Tracking the establishment of local endemic populations of an emergent enteric pathogen

scientific article published on 30 September 2013

Transcriptional profiling of macrophages derived from monocytes and iPS cells identifies a conserved response to LPS and novel alternative transcription

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Transcriptional response in the peripheral blood of patients infected with Salmonella enterica serovar Typhi

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Transcriptome of enterohemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes

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Transfer of scarlet fever-associated elements into the group A Streptococcus M1T1 clone

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Transient Darwinian selection in Salmonella enterica serovar Paratyphi A during 450 years of global spread of enteric fever

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Typhoid fever

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Typhoid fever in Fiji: a reversible plague?

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Typhoid in Africa and vaccine deployment

scientific article published in March 2017

Typhoid in Kenya is associated with a dominant multidrug-resistant Salmonella enterica serovar Typhi haplotype that is also widespread in Southeast Asia

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Tyrosine residues at the immunoglobulin-C-type lectin inter-domain boundary of intimin are not involved in Tir-binding but implicated in colonisation of the host

scientific article published in November 2002

Unlocking the genome of the human typhoid bacillus

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Use of paired serum samples for serodiagnosis of typhoid fever

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Use of purified Clostridium difficile spores to facilitate evaluation of health care disinfection regimens

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Using Human Induced Pluripotent Stem Cell-derived Intestinal Organoids to Study and Modify Epithelial Cell Protection Against Salmonella and Other Pathogens

scientific article published on 12 May 2019

Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a

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Using a Systems Biology Approach To Study Host-Pathogen Interactions

scientific article published on 01 March 2019

Vaccines against human enteric bacterial pathogens

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Variation in Salmonella enterica serovar typhi IncHI1 plasmids during the global spread of resistant typhoid fever

scientific article published on 17 November 2008

Vi antigen expression in Salmonella enterica serovar Typhi clinical isolates from Pakistan

scientific article published on March 2005

Vitamin B₁₂-dependent taurine synthesis regulates growth and bone mass

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Wave 2 strains of atypical Vibrio cholerae El Tor caused the 2009-2011 cholera outbreak in Papua New Guinea

scientific article published on 27 February 2019

What is the best immunization strategy for protecting African children against invasive Salmonella disease?

scientific article published on 01 November 2018