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List of works by Doreen Cantrell

A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation.

scientific article

AMPKα1: a glucose sensor that controls CD8 T-cell memory

scientific article published on 13 February 2013

Adenosine-mono-phosphate-activated protein kinase-independent effects of metformin in T cells

scientific article

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice.

scientific article published on 14 June 2018

Antigen receptor control of methionine metabolism in T cells

scientific article published on 27 March 2019

Antigen receptor regulation of phosphoinositide-dependent kinase 1 pathways during thymocyte development

scientific article published on 28 September 2006

Approaches to define antigen receptor-induced serine kinase signal transduction pathways

scientific article

Commentary Vav-1 and T cells

scientific article published on 01 April 2003

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

scientific article published on 24 March 2013

Diacylglycerol and Protein Kinase D Localization during T Lymphocyte Activation ⬇️

Differential regulation of T-cell growth by IL-2 and IL-15

scientific article published on 28 March 2006

Differential requirement for RhoA GTPase depending on the cellular localization of protein kinase D.

scientific article

Dual phospholipase C/diacylglycerol requirement for protein kinase D1 activation in lymphocytes.

scientific article

Environmental and metabolic sensors that control T cell biology

scientific article published on 17 March 2015

Erratum: Corrigendum: Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

scholarly article by Linda V Sinclair et al published January 2014 in Nature Immunology

Erratum: Corrigendum: Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

scholarly article published in Nature Immunology

Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes

scientific article published on February 2006

Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors

scientific article published on November 2002

Extracellular signal-regulated kinase (ERK) pathway control of CD8+ T cell differentiation

scientific article published on 11 December 2020

GTPases and T cell activation

scientific article

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

scientific article published on 25 April 2016

ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation.

scientific article

Identification of pro-interleukin 16 as a novel target of MAP kinases in activated T lymphocytes

scientific article published in February 2004

Integrin regulation by RhoA in thymocytes

scientific article published in July 2005

Interleukin (IL)-2 activation of p21ras in murine myeloid cells transfected with human IL-2 receptor β chain

scholarly article by Manuel Izquierdo et al published March 1992 in European Journal of Immunology

Interleukin-2 shapes the cytotoxic T cell proteome and immune environment-sensing programs.

scientific article published on 17 April 2018

Intracellular Location and Cell Context-Dependent Function of Protein Kinase D

scientific article published on 01 October 2003

LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells

scientific article published on January 2010

LKB1 mediates the development of conventional and innate T cells via AMP-dependent kinase autonomous pathways

scientific article

Mathematical Models for Immunology: Current State of the Art and Future Research Directions

scientific article published on 6 October 2016

Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.

scientific article published on 11 May 2015

Metabolism, migration and memory in cytotoxic T cells ⬇️

scientific article published on January 14, 2011

Move to metabolism

scientific article published on 01 May 2019

New insights into the regulation and function of serine/threonine kinases in T lymphocytes

scientific article published on March 2009

Notch-induced T cell development requires phosphoinositide-dependent kinase 1.

scientific article published on 28 June 2007

Of Mosaicism and Mechanisms: How JAK1 Goes Awry

scientific article published on 01 September 2020

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

scientific article published on 26 November 2012

Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation

article

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

scientific article

Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation

scientific article published on 24 August 2009

Phosphoinositide 3-kinase and the mammalian target of rapamycin pathways control T cell migration

scientific article published on January 2010

Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

scientific article published on 5 October 2009

Phosphoinositide-dependent kinase l (PDK1) haplo-insufficiency inhibits production of alpha/beta (alpha/beta) but not gamma delta (gamma/delta) T lymphocytes.

scientific article

Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D.

scientific article

Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8(+) T Cells

scientific article

Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes

scientific article

Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition

scientific article (publication date: 4 November 2016)

Protein kinase B (Akt) regulation and function in T lymphocytes

scientific article

Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism

scientific article

Protein kinase C and beyond

scientific article published in August 2004

Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2

scientific article published on 28 April 2011

Protein kinase D enzymes are dispensable for proliferation, survival and antigen receptor-regulated NFkappaB activity in vertebrate B-cells

scientific article

Protein kinase D is a downstream target of protein kinase Ctheta

scientific article

Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues

scientific article published on May 2012

Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells

scientific article published on March 2012

Protein kinase D2 is a digital amplifier of T cell receptor-stimulated diacylglycerol signaling in naïve CD8⁺ T cells

scientific article published on 21 October 2014

Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation

scientific article published on 07 October 2019

Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

scientific article published on 05 February 2020

Quantitative phosphoproteomics of cytotoxic T cells to reveal protein kinase d 2 regulated networks.

scientific article published on 29 September 2014

Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling

scientific article published on 11 February 2002

Regulation and function of serine kinase networks in lymphocytes

scientific article

Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site

scientific article (publication date: 31 May 2002)

Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes.

scientific article published on 3 July 2006

Serine-threonine kinases in TCR signaling.

scientific article

Signaling and Function of Interleukin-2 in T Lymphocytes.

scientific article published in April 2018

Signaling in lymphocyte activation

scientific article published on June 2015

Single Cell Glucose Uptake Assays: A Cautionary Tale

scientific article published on 17 August 2020

Single cell analysis of kynurenine and System L amino acid transport in T cells.

scientific article

Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes.

scientific article published on July 2015

Stimulation of p21 ras upon T-cell activation

scientific article published in Nature

Sustained IL-12 signaling is required for Th1 development

scientific article published in January 2004

Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse

scientific article published on 21 October 2002

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

scholarly article

T-cell antigen receptor signal transduction

Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cells

scientific article

The BAFF receptor transduces survival signals by co-opting the B cell receptor signaling pathway.

scientific article published on 28 February 2013

The Coordination of T-cell Function by Serine/Threonine Kinases ⬇️

scientific article published on January 1, 2011

The active inner life of naive T cells

scientific article published on 06 July 2020

The cytotoxic T cell proteome and its shaping by the kinase mTOR.

scientific article

The impact of KLF2 modulation on the transcriptional program and function of CD8 T cells

scientific article

The role of serine/threonine kinases in T-cell activation

scientific article

The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development

scientific article published on 11 April 2004

Transgenic analysis of thymocyte signal transduction

scientific article

Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells

scientific journal article

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