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List of works by Yoon Bo Hyun

"Early rupture of membranes" after the spontaneous onset of labor as a risk factor for cesarean delivery

scientific article published on 14 December 2009

399: The earlier the gestational age in preterm PROM, the greater the intensity of the intra-amniotic inflammatory response in patients with Ureaplasma infections

433: Intra-amniotic infection with genital mycoplasmas is characterized by an intense inflammatory response in the amniotic cavity and in the maternal compartment

434: The frequency and clinical significance of intra-amniotic inflammation in twin pregnancies with preterm labor and intact membranes

article by Kyung Joon Oh et al published December 2009 in American Journal of Obstetrics and Gynecology

464: The frequency and prognostic significance of intra-amniotic inflammation in preterm premature rupture of membranes before 25 weeks

468: The intraamniotic and fetal inflammatory response is more intense in preterm labor with intact membranes than in preterm PROM

497: Fetal death: an extreme form of maternal anti-fetal rejection

article published in 2015

509: Acute histologic choriodeciduitis is associated with an intra-amniotic inflammatory response, but not a maternal and fetal inflammatory response: implications of the staging of inflammation of the chorioamniotic membranes

513: The relationship between the severity of histologic chorioamnionitis and the intensity of fetal inflammatory response

524: Histologic chorioamnionitis is a risk factor for adverse neonatal outcome in late preterm birth following preterm PROM

524: Intra-amniotic inflammation in patients with a positive Amnisure test in preterm labor and intact membranes

525: Histologic chorioamnionitis is a risk factor for adverse neonatal outcomes in late preterm infants who delivered after premature rupture of membranes (PPROM)

scientific article published in January 2012

528: A role for placental alpha-microglobulin-1 in the identification of women with a sonographic short cervix at risk for spontaneous rupture of membranes

561: A high cervical fetal fibronectin concentration increases the risk of intra-amniotic infection/inflammation in preterm labor

599: A receptor for danger signals, advanced glycation end products (RAGE) in fetal systemic inflammation and clinical chorioamnionitis

614: Evidence in support that spontaneous preterm labor is adaptive in nature: Neonatal RDS is more common in “indicated” than in “spontaneous” preterm birth

article by Joonho Lee et al published December 2007 in American Journal of Obstetrics and Gynecology

664: Preterm labor in twin gestations: a point of care test to identify impending preterm delivery and intra-amniotic infection

article by Kyung Joon Oh et al published January 2016 in American Journal of Obstetrics and Gynecology

689: Evidence supporting that a culture-proven infection has clinical implications beyond the presence of intra-amniotic inflammation with a negative amniotic fluid culture in preterm PROM

article by Si Eun Lee et al published December 2007 in American Journal of Obstetrics and Gynecology

798: Systemic inflammatory stimulation by microparticles derived from hypoxic trophoblast in preeclampsia

A "multi-hit" model of neonatal white matter injury: cumulative contributions of chronic placental inflammation, acute fetal inflammation and postnatal inflammatory events

scientific article published on November 2014

A Fetal and an Intra-Amniotic Inflammatory Response Is More Severe in Preterm Labor than in Preterm PROM in the Context of Funisitis: Unexpected Observation in Human Gestations ⬇️

scientific article published on January 1, 2013

A comparative study of the diagnostic performance of amniotic fluid glucose, white blood cell count, interleukin-6, and Gram stain in the detection of microbial invasion in patients with preterm premature rupture of membranes

article

A high Nugent score but not a positive culture for genital mycoplasmas is a risk factor for spontaneous preterm birth

scientific article published on March 2009

A high concentration of fetal fibronectin in cervical secretions increases the risk of intra-amniotic infection and inflammation in patients with preterm labor and intact membranes

scientific article published on 01 April 2019

A link between a hemostatic disorder and preterm PROM: a role for tissue factor and tissue factor pathway inhibitor

scientific article

A new anti-microbial combination prolongs the latency period, reduces acute histologic chorioamnionitis as well as funisitis, and improves neonatal outcomes in preterm PROM.

scientific article published on 16 September 2015

A new antibiotic regimen treats and prevents intra-amniotic inflammation/infection in patients with preterm PROM.

scientific article published on 6 October 2015

A new rapid bedside test to diagnose and monitor intra-amniotic inflammation in preterm PROM using transcervically collected fluid

scientific article published on 27 February 2020

A novel molecular microbiologic technique for the rapid diagnosis of microbial invasion of the amniotic cavity and intra-amniotic infection in preterm labor with intact membranes ⬇️

scientific article published on 13 January 2014

A point of care test for interleukin-6 in amniotic fluid in preterm prelabor rupture of membranes: a step toward the early treatment of acute intra-amniotic inflammation/infection

scientific article published on 10 March 2015

A point of care test for the determination of amniotic fluid interleukin-6 and the chemokine CXCL-10/IP-10

scientific article published on 20 October 2014

A rapid MMP-8 bedside test for the detection of intra-amniotic inflammation identifies patients at risk for imminent preterm delivery.

scientific article

A rapid interleukin-6 bedside test for the identification of intra-amniotic inflammation in preterm labor with intact membranes

scientific article published on 10 March 2015

A rapid matrix metalloproteinase-8 bedside test for the detection of intraamniotic inflammation in women with preterm premature rupture of membranes.

scientific article

A role for the 72 kDa gelatinase (MMP-2) and its inhibitor (TIMP-2) in human parturition, premature rupture of membranes and intraamniotic infection

article

A short cervix in women with preterm labor and intact membranes: a risk factor for microbial invasion of the amniotic cavity

scientific article

A signature of maternal anti-fetal rejection in spontaneous preterm birth: chronic chorioamnionitis, anti-human leukocyte antigen antibodies, and C4d

scientific article

A transcervical amniotic fluid collector: a new medical device for the assessment of amniotic fluid in patients with ruptured membranes.

scientific article published in July 2015

About one-half of early spontaneous preterm deliveries can be identified by a rapid matrix metalloproteinase-8 (MMP-8) bedside test at the time of mid-trimester genetic amniocentesis.

scientific article published on 7 December 2015

Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance

scientific article published on October 2015

Acute funisitis is associated with distinct changes in fetal hematologic profile

scientific article published on 20 June 2014

Acute histologic chorioamnionitis is a risk factor for adverse neonatal outcome in late preterm birth after preterm premature rupture of membranes

scientific article

Adiponectin in severe preeclampsia.

scientific article published on January 2007

Alteration of Pituitary Tumor Transforming Gene-1 Regulates Trophoblast Invasion via the Integrin/Rho-Family Signaling Pathway

scientific article

Amniotic fluid interleukin-6: A sensitive test for antenatal diagnosis of acute inflammatory lesions of preterm placenta and prediction of perinatal morbidity

Amniotic fluid matrix metalloproteinase-8 and the development of cerebral palsy.

scientific article published on January 2002

Amniotic fluid prostaglandin F2 increases even in sterile amniotic fluid and is an independent predictor of impending delivery in preterm premature rupture of membranes

scientific article published on October 2009

Amniotic fluid prostaglandin concentrations increase before the onset of spontaneous labor at term.

scientific article published in February 2008

Amniotic fluid tumor necrosis factor-alpha is a marker for the prediction of early-onset neonatal sepsis in preterm labor

scientific article published on 12 May 2004

Amniotic fluid volume in intra-amniotic inflammation with and without culture-proven amniotic fluid infection in preterm premature rupture of membranes

scientific article

An elevated amniotic fluid prostaglandin F2α concentration is associated with intra-amniotic inflammation/infection, and clinical and histologic chorioamnionitis, as well as impending preterm delivery in patients with preterm labor and intact membra

scientific article published on 15 December 2015

An elevated maternal plasma, but not amniotic fluid, soluble fms-like tyrosine kinase-1 (sFlt-1) at the time of mid-trimester genetic amniocentesis is a risk factor for preeclampsia

scientific article

An elevated maternal serum C-reactive protein in the context of intra-amniotic inflammation is an indicator that the development of amnionitis, an intense fetal and AF inflammatory response are likely in patients with preterm labor: clinical implica

scientific article published on June 1, 2013

An increase in fetal plasma cortisol but not dehydroepiandrosterone sulfate is followed by the onset of preterm labor in patients with preterm premature rupture of the membranes

scholarly article by B H Yoon et al published November 1998 in American Journal of Obstetrics and Gynecology

Angiotensinogen G(-6)A polymorphism is associated with the elevation of blood pressure in the hypertensive disorders of pregnancy

scientific article

Antibiotic administration can eradicate intra-amniotic infection or intra-amniotic inflammation in a subset of patients with preterm labor and intact membranes

scientific article published on 27 March 2019

Bacteria and endotoxin in meconium-stained amniotic fluid at term: could intra-amniotic infection cause meconium passage?

scientific article published on 16 December 2013

Biovar diversity of Ureaplasma urealyticum in amniotic fluid: distribution, intrauterine inflammatory response and pregnancy outcomes

scientific article published on 01 January 2003

Blood pH and gases in fetuses in preterm labor with and without systemic inflammatory response syndrome

scientific article

C-reactive protein concentration in vaginal fluid as a marker for intra-amniotic inflammation/infection in preterm premature rupture of membranes.

scientific article published on December 2005

CXCL10 and IL-6: Markers of two different forms of intra-amniotic inflammation in preterm labor

scientific article

CXCL10/IP-10: a missing link between inflammation and anti-angiogenesis in preeclampsia?

scientific article published on November 2007

Can heparin prevent adverse pregnancy outcome?

Changes in amniotic fluid concentration of thrombin-antithrombin III complexes in patients with preterm labor: evidence of an increased thrombin generation

scientific article

Characterization of the fetal blood transcriptome and proteome in maternal anti-fetal rejection: evidence of a distinct and novel type of human fetal systemic inflammatory response

scientific article published on 30 July 2013

Chorionic plate vessels as an origin of amniotic fluid neutrophils

scientific article published on 01 July 2004

Clinical Chorioamnionitis at Term: New Insights into the Etiology, Microbiology, and the Fetal, Maternal and Amniotic Cavity Inflammatory Responses

article

Clinical chorioamnionitis at term I: microbiology of the amniotic cavity using cultivation and molecular techniques

scientific article published on January 2015

Clinical chorioamnionitis at term II: the intra-amniotic inflammatory response

scientific article published on May 2015

Clinical chorioamnionitis at term III: how well do clinical criteria perform in the identification of proven intra-amniotic infection?

scientific article published on 28 April 2015

Clinical chorioamnionitis at term IV: the maternal plasma cytokine profile

scientific article published on 4 August 2015

Clinical chorioamnionitis at term V: umbilical cord plasma cytokine profile in the context of a systemic maternal inflammatory response

scientific article published on 11 September 2015

Clinical chorioamnionitis at term VI: acute chorioamnionitis and funisitis according to the presence or absence of microorganisms and inflammation in the amniotic cavity

scientific article published on September 2015

Clinical significance of intra-amniotic inflammation in patients with preterm premature rupture of membranes.

scientific article

Clinical significance of oligohydramnios in patients with preterm labor and intact membranes

scientific article

Coexpression of myofibroblast and macrophage markers: novel evidence for an in vivo plasticity of chorioamniotic mesodermal cells of the human placenta

scientific article published on 28 January 2008

Detection and biovar discrimination of Ureaplasma urealyticum by real-time PCR.

scientific article published in August 2005

Detection of anti-HLA antibodies in maternal blood in the second trimester to identify patients at risk of antibody-mediated maternal anti-fetal rejection and spontaneous preterm delivery

scientific article

Detection of ureaplasmas by the polymerase chain reaction in the amniotic fluid of patients with cervical insufficiency

scientific article

Differential activation of mitogen activated protein kinases and nuclear factor-kappaB in lipopolysaccharide-treated term and preterm amnion cells

scientific article published on 01 June 2005

Dysregulation of maternal serum adiponectin in preterm labor

scientific article published on October 2009

Evidence for a spatial and temporal regulation of prostaglandin-endoperoxide synthase 2 expression in human amnion in term and preterm parturition

scientific article

Evidence for fetal involvement in the pathologic process of clinical chorioamnionitis

scientific article

Evidence of changes in the immunophenotype and metabolic characteristics (intracellular reactive oxygen radicals) of fetal, but not maternal, monocytes and granulocytes in the fetal inflammatory response syndrome

scientific article published on January 2009

Evidence of the involvement of caspase-1 under physiologic and pathologic cellular stress during human pregnancy: a link between the inflammasome and parturition

scientific article

Evidence supporting proteolytic cleavage of insulin-like growth factor binding protein-1 (IGFBP-1) protein in amniotic fluid

scientific article

Evidence that antibiotic administration is effective in the treatment of a subset of patients with intra-amniotic infection/inflammation presenting with cervical insufficiency

scientific article published on 28 March 2019

Evidence to support that spontaneous preterm labor is adaptive in nature: neonatal RDS is more common in "indicated" than in "spontaneous" preterm birth

scientific article

Expression of bone morphogenetic protein 2 in normal spontaneous labor at term, preterm labor, and preterm premature rupture of membranes.

scientific article

FGR in the setting of preterm sterile intra-uterine milieu is associated with a decrease in RDS.

scientific article published on 29 December 2015

Failure of physiologic transformation of the spiral arteries in patients with preterm labor and intact membranes

scientific article published on October 2003

Failure of physiologic transformation of the spiral arteries in the placental bed in preterm premature rupture of membranes

Fetal death: an extreme manifestation of maternal anti-fetal rejection

scientific article published on September 2017

Fetal plasma MMP-9 concentrations are elevated in preterm premature rupture of the membranes

scientific article

Fetal plasma cortisol and dehydroepiandrosterone sulfate concentrations in pregnancy and term parturition.

scientific article published in September 2006

Fetal ventriculomegaly: prognosis in cases in which prenatal neurosurgical consultation was sought

scientific article

Fetal, amniotic and maternal inflammatory responses in early stage of ascending intrauterine infection, inflammation restricted to chorio-decidua, in preterm gestation ⬇️

scientific article published on July 11, 2013

Fragmented Forms of Insulin-Like Growth Factor Binding Protein-1 in Amniotic Fluid of Patients With Preterm Labor and Intact Membranes ⬇️

scientific article published on March 18, 2011

Funisitis in term pregnancy is associated with microbial invasion of the amniotic cavity and intra-amniotic inflammation

scientific article published on 01 November 2006

Further observations on the fetal inflammatory response syndrome: A potential homeostatic role for the soluble receptors of tumor necrosis factor α

article

Gastric fluid versus amniotic fluid analysis for the identification of intra-amniotic infection due to Ureaplasma species.

scientific article

Hematologic profile of the fetus with systemic inflammatory response syndrome

scientific article

High tissue factor activity and low tissue factor pathway inhibitor concentrations in patients with preterm labor

scientific article

Hyperresistinemia - a novel feature in systemic infection during human pregnancy

scientific article

Idiopathic Fetal Death Is Associated with Evidence of Prior Antigenic Exposure

article

Increased miR-223 expression in foetal organs is a signature of acute chorioamnionitis with systemic consequences.

scientific article

Intraamniotic infection with genital mycoplasmas exhibits a more intense inflammatory response than intraamniotic infection with other microorganisms in patients with preterm premature rupture of membranes

Intrauterine infection and the development of cerebral palsy

scientific article

Lactoferrin in intrauterine infection, human parturition, and rupture of fetal membranes

Maternal and neonatal circulating visfatin concentrations in patients with pre-eclampsia and a small-for-gestational age neonate

scientific article

Maternal plasma angiogenic index-1 (placental growth factor/soluble vascular endothelial growth factor receptor-1) is a biomarker for the burden of placental lesions consistent with uteroplacental underperfusion: a longitudinal case-cohort study

scientific article published on 11 December 2015

Maternal plasma osteoprotegerin concentration in normal pregnancy

scientific article

Maternal serum adiponectin multimers in gestational diabetes

scientific article published on January 2009

Maternal serum adiponectin multimers in patients with a small-for-gestational-age newborn

scientific article published on January 2009

Maternal serum adiponectin multimers in preeclampsia

scientific article

Maternal serum soluble CD30 is increased in normal pregnancy, but decreased in preeclampsia and small for gestational age pregnancies

scientific article published on December 2007

Maternal serum soluble CD30 is increased in pregnancies complicated with acute pyelonephritis

scientific article published on November 2007

Matrix metalloproteinase 3 in parturition, premature rupture of the membranes, and microbial invasion of the amniotic cavity

article by Kyo Hoon Park et al published 27 January 2003 in Journal of Perinatal Medicine

Meconium aspiration syndrome: a role for fetal systemic inflammation

scientific article published on 17 October 2015

Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery

scientific article

Metformin, the Aspirin of the 21st Century

Metformin, the aspirin of the 21st century: its role in gestational diabetes mellitus, prevention of preeclampsia and cancer, and the promotion of longevity

scientific article

Midtrimester amniotic fluid concentrations of interleukin-6 and interferon-gamma-inducible protein-10: evidence for heterogeneity of intra-amniotic inflammation and associations with spontaneous early (<32 weeks) and late (>32 weeks) preterm deliver

scientific article

Mild to Moderate, but Not Minimal or Severe, Acute Histologic Chorioamnionitis or Intra-Amniotic Inflammation Is Associated with a Decrease in Respiratory Distress Syndrome of Preterm Newborns without Fetal Growth Restriction

scientific article published on 18 June 2015

Patients with an asymptomatic short cervix (<or=15 mm) have a high rate of subclinical intraamniotic inflammation: implications for patient counseling

scientific article

Placental C4d deposition is a feature of defective placentation: observations in cases of preeclampsia and miscarriage

scientific article published on 28 March 2015

Plasma adiponectin concentrations in non-pregnant, normal and overweight pregnant women.

scientific article published on January 2007

Plasma protein Z concentrations in pregnant women with idiopathic intrauterine bleeding and in women with spontaneous preterm labor

scientific article published on June 2007

Pregnancy outcomes in women with mechanical heart valves.

scientific article

Preterm labor and preterm premature rupture of membranes have a different pattern in the involved compartments of acute histologoic chorioamnionitis and/or funisitis: Patho-physiologic implication related to different clinical manifestations

scientific article published on 18 April 2016

Prevalence and clinical significance of sterile intra-amniotic inflammation in patients with preterm labor and intact membranes

scientific article

Progesterone receptor isoform (A/B) ratio of human fetal membranes increases during term parturition.

scientific article published on September 2005

Promyelocytic leukaemia (PML) protein expression in human placenta and choriocarcinoma

scientific article published in September 2003

Proteomic profiling of amniotic fluid in preterm labor using two-dimensional liquid separation and mass spectrometry

scientific article

Relationship between twin-to-twin delivery interval and umbilical artery acid-base status in the second twin

scientific article published on April 2007

Secreted phospholipase A2 is increased in meconium-stained amniotic fluid of term gestations: potential implications for the genesis of meconium aspiration syndrome

scientific article

Signature pathways identified from gene expression profiles in the human uterine cervix before and after spontaneous term parturition

scientific article published on September 2007

Spontaneous Term Labor Is Associated with Increased Fetal Plasma Concentrations of Interleukin-6

Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes

scientific article published on 29 September 2014

Sterile intra-amniotic inflammation in asymptomatic patients with a sonographic short cervix: prevalence and clinical significance

scientific article

Systemic inflammatory stimulation by microparticles derived from hypoxic trophoblast as a model for inflammatory response in preeclampsia

scientific article

The antenatal identification of funisitis with a rapid MMP-8 bedside test

scientific article

The anti-inflammatory limb of the immune response in preterm labor, intra-amniotic infection/inflammation, and spontaneous parturition at term: A role for interleukin-10

article

The clinical significance of a positive Amnisure test in women with preterm labor and intact membranes

scientific article

The clinical significance of a positive Amnisure test in women with term labor with intact membranes

scientific article published on April 2009

The clinical significance of detecting Ureaplasma urealyticum by the polymerase chain reaction in the amniotic fluid of patients with preterm labor

scientific article published on 01 October 2003

The combined exposure to intra-amniotic inflammation and neonatal respiratory distress syndrome increases the risk of intraventricular hemorrhage in preterm neonates.

scientific article

The diagnostic and prognostic value of amniotic fluid white blood cell count, glucose, interleukin-6, and Gram stain in patients with preterm labor and intact membranes

article

The earlier the gestational age, the greater the intensity of the intra-amniotic inflammatory response in women with preterm premature rupture of membranes and amniotic fluid infection by Ureaplasma species

scientific article published on 01 July 2019

The fetal inflammatory response syndrome: the origins of a concept, pathophysiology, diagnosis, and obstetrical implications

scientific article published on 01 August 2020

The frequency and clinical significance of intra-amniotic inflammation defined as an elevated amniotic fluid matrix metalloproteinase-8 in patients with preterm labor and low amniotic fluid white blood cell counts

scientific article published on 16 May 2013

The frequency and clinical significance of intra-amniotic inflammation in twin pregnancies with preterm labor and intact membranes

scientific article published on 11 October 2017

The frequency and clinical significance of intra-amniotic inflammation in women with preterm uterine contractility but without cervical change: do the diagnostic criteria for preterm labor need to be changed?

scientific article published on 25 April 2012

The frequency and risk factors of funisitis and histologic chorioamnionitis in pregnant women at term who delivered after the spontaneous onset of labor

scientific article

The frequency and significance of intraamniotic inflammation in patients with cervical insufficiency

scientific article published on 14 March 2008

The frequency of meconium-stained amniotic fluid increases as a function of the duration of labor

scientific article published on 17 March 2011

The frequency of microbial invasion of the amniotic cavity and histologic chorioamnionitis in women at term with intact membranes in the presence or absence of labor ⬇️

scientific article published on October 2008

The frequency, clinical significance, and pathological features of chronic chorioamnionitis: a lesion associated with spontaneous preterm birth.

scientific article

The importance of intra-amniotic inflammation in the subsequent development of atypical chronic lung disease

scientific article published in October 2009

The inflammatory milieu of amniotic fluid in acute-chorioamnionitis decreases with increasing gestational age

scientific article published on 26 September 2015

The intensity of the fetal inflammatory response in intraamniotic inflammation with and without microbial invasion of the amniotic cavity

scientific article published in September 2007

The involvement of human amnion in histologic chorioamnionitis is an indicator that a fetal and an intra-amniotic inflammatory response is more likely and severe: clinical implications

scientific article

The prediction of fetal death with a simple maternal blood test at 20-24 weeks: a role for angiogenic index-1 (PlGF/sVEGFR-1 ratio).

scientific article published on 13 October 2017

The prognosis of pregnancy conceived despite the presence of an intrauterine device (IUD).

scientific article

The relationship between the intensity of intra-amniotic inflammation and the presence and severity of acute histologic chorioamnionitis in preterm gestation

scientific article

The risk of intra-amniotic infection, inflammation and histologic chorioamnionitis in term pregnant women with intact membranes and labor ⬇️

scientific article published on May 11, 2011

The risk of neonatal respiratory morbidity according to the etiology of late preterm delivery

scientific article published on 12 April 2016

The role of granulocyte colony-stimulating factor in the neutrophilia observed in the fetal inflammatory response syndrome

scientific article

The tumor necrosis factor α and its soluble receptor profile in term and preterm parturition

article by E Maymon et al published November 1999 in American Journal of Obstetrics and Gynecology

Timing of Histologic Progression from Chorio-Deciduitis to Chorio-Deciduo-Amnionitis in the Setting of Preterm Labor and Preterm Premature Rupture of Membranes with Sterile Amniotic Fluid

scientific article published on 17 November 2015

Tissue factor and its natural inhibitor in pre-eclampsia and SGA

scientific article

Toward a new taxonomy of obstetrical disease: improved performance of maternal blood biomarkers for the great obstetrical syndromes when classified according to placental pathology

scientific article published in 2022

Twenty-four percent of patients with clinical chorioamnionitis in preterm gestations have no evidence of either culture-proven intraamniotic infection or intraamniotic inflammation.

scientific article published on 28 February 2017

Viral invasion of the amniotic cavity (VIAC) in the midtrimester of pregnancy. ⬇️

scientific article

Which is more important for the intensity of intra-amniotic inflammation between total grade or involved anatomical region in preterm gestations with acute histologic chorioamnionitis?

scientific article published on 15 July 2013

“Early Rupture of Membranes” during Induced Labor as a Risk Factor for Cesarean Delivery in Term Nulliparas ⬇️

scientific article published on June 29, 2012

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