List of works - Suh Yoo-hun

15-deoxy-Δ¹²,¹⁴ -prostaglandin J₂ inhibits human immunodeficiency virus-1 tat-induced monocyte chemoattractant protein-1/CCL2 production by blocking the extracellular signal-regulated kinase-1/2 signaling pathway independently of peroxisome prolifer

scientific article published on 9 April 2012

A novel compound, maltolyl p-coumarate, attenuates cognitive deficits and shows neuroprotective effects in vitro and in vivo dementia models.

scientific article published in August 2007

A novel, selective, and extremely responsive thienyl-based dual fluorogenic probe for tandem superoxide and Hg2+ chemosensing.

scientific article

Alpha-synuclein induces apoptosis by altered expression in human peripheral lymphocyte in Parkinson's disease

scientific article published on 02 August 2004

Alpha-synuclein induces migration of BV-2 microglial cells by up-regulation of CD44 and MT1-MMP.

scientific article

Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway

scientific article published on 5 September 2002

Alpha-synuclein, Parkinson's disease, and Alzheimer's disease

scientific article

Amyloid Precursor Protein Binding Protein-1 Is Up-regulated in Brains of Tg2576 Mice ⬇️

scientific article published on August 31, 2010

Amyloid beta peptide induces cytochrome C release from isolated mitochondria

scientific article published in October 2002

Amyloid precursor protein binding protein-1 knockdown reduces neuronal differentiation in fetal neural stem cells ⬇️

scientific article published on January 25, 2012

Amyloid precursor protein binding protein-1 modulates cell cycle progression in fetal neural stem cells

scientific article

Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

scientific article

Amyloid-β peptide-induced extracellular S100A9 depletion is associated with decrease of antimicrobial peptide activity in human THP-1 monocytes

scientific article published on 30 May 2013

An Activity-Regulated microRNA, miR-188, Controls Dendritic Plasticity and Synaptic Transmission by Downregulating Neuropilin-2 ⬇️

scientific article published on April 18, 2012

BT-11 improves stress-induced memory impairments through increment of glucose utilization and total neural cell adhesion molecule levels in rat brains

scientific article published in January 2009

BT-11 is effective for enhancing cognitive functions in the elderly humans

scientific article (publication date: November 2009)

Beta-amyloid peptide binding protein does not couple to G protein in a heterologous Xenopus expression system

scientific article

Biphasic electrical currents stimulation promotes both proliferation and differentiation of fetal neural stem cells

scientific article

C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression.

scientific article published on 15 August 2003

Carboxyl-terminal peptide of beta-amyloid precursor protein blocks inositol 1,4,5-trisphosphate-sensitive Ca2+ release in Xenopus laevis oocytes

scientific article

Cdk5 phosphorylates dopamine D2 receptor and attenuates downstream signaling

scientific article

Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model

scientific article published on 8 February 2006

Correction: Biphasic Electrical Currents Stimulation Promotes both Proliferation and Differentiation of Fetal Neural Stem Cells.

scientific article published on 10 May 2011

Cyclic AMP inhibition of tumor necrosis factor alpha production induced by amyloidogenic C-terminal peptide of Alzheimer's amyloid precursor protein in macrophages: involvement of multiple intracellular pathways and cyclic AMP response element bindi

scientific article

Cyclin-dependent kinase 5 (Cdk5) regulates the function of CLOCK protein by direct phosphorylation

scientific article published on 14 November 2013

Cytoskeletal Pathologies of Age-Related Diseases between Elderly Sri Lankan (Colombo) and Indian (Bangalore) Brain Samples

scientific article

Dehydroevodiamine·HCl Improves Stress-Induced Memory Impairments and Depression Like Behavior in Rats

scientific article published on 13 February 2014

Dehydroevodiamine·HCl enhances cognitive function in memory-impaired rat models

scientific article published on 21 December 2016

Dehydroevodiamine•HCl Protects Against Memory Impairment and Cerebral Amyloid-β Production in Tg2576 Mice by Acting as a β-Secretase Inhibitor

scientific article published on 15 August 2016

Differential functions of NR2A and NR2B in short-term and long-term memory in rats

scientific journal article

Differential spatial expression of peripheral olfactory neuron-derived BACE1 induces olfactory impairment by region-specific accumulation of β-amyloid oligomer

scientific article

Distinct amyloid precursor protein processing machineries of the olfactory system

scientific article published on 30 October 2017

Dopamine and Cu+/2+ can induce oligomerization of α-synuclein in the absence of oxygen: Two types of oligomerization mechanisms for α-synuclein and related cell toxicity studies

scientific article published on 29 November 2013

Early stages of Alzheimer's disease are alarming signs in injury deaths caused by traffic accidents in elderly people (≥60 years of age): A neuropathological study

scientific article published in October 2017

Editorial (Thematic Issue: Molecular and Cellular Engineering Approaches for Neurological Disorders, Diseases, and Injuries Involved the Central and Peripheral Nervous Systems).

scientific article published in January 2016

Effects of BT-11 on memory in healthy humans

scientific article (publication date: 24 April 2009)

Effects of a Dehydroevodiamine-Derivative on Synaptic Destabilization and Memory Impairment in the 5xFAD, Alzheimer's Disease Mouse Model

scholarly article by Shinwoo Kang et al published 2018 in Frontiers in Behavioral Neuroscience

Effects of intrahippocampal CT105, a carboxyl terminal fragment of beta-amyloid precursor protein, alone/with inflammatory cytokines on working memory in rats

scientific article

Effects of the monomeric, oligomeric, and fibrillar Abeta42 peptides on the proliferation and differentiation of adult neural stem cells from subventricular zone

scientific article published on 30 April 2007

Environmental enrichment compensates for the effects of stress on disease progression in Tg2576 mice, an Alzheimer's disease model

scientific article

Extremely selective "turn-on" fluorescence detection of hypochlorite confirmed by proof-of-principle neurological studies via esterase action in living cells.

scientific article

FE65 as a link between VLDLR and APP to regulate their trafficking and processing

scientific journal article

Facile "stop codon" method reveals elevated neuronal toxicity by discrete S87p-α-synuclein oligomers

scientific article published on 28 December 2013

Focal transient ischemia increases APP-BP1 expression in neural progenitor cells ⬇️

scientific article published on March 30, 2011

General pharmacology of indole [2',3':3,4]pyrido[2,1-b]quinazolinium- 5,7,8,13-tetrahydro-14-methyl-5-oxo-chloride, a new anti-dementia agent

scientific article published in January 2003

Human adipose-derived stem cells ameliorate repetitive behavior, social deficit and anxiety in a VPA-induced autism mouse model

scientific article published on 4 October 2016

Huntingtin is localized in the nucleus during preimplanatation embryo development in mice

scientific article published on 14 November 2005

In vivo imaging of human adipose-derived stem cells in Alzheimer's disease animal model

scientific article published in May 2014

Increased tau phosphorylation on mitogen-activated protein kinase consensus sites and cognitive decline in transgenic models for Alzheimer's disease and FTDP-17: evidence for distinct molecular processes underlying tau abnormalities

scientific article

Inhibition of histone deacetylation enhances the neurotoxicity induced by the C-terminal fragments of amyloid precursor protein

scientific article published in January 2004

Interplay of salicylaldehyde, lysine, and M2+ ions on α-synuclein aggregation: cancellation of aggregation effects and determination of salicylaldehyde neurotoxicity.

scientific article

Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau

scientific article

Long-lasting facilitation by dehydroevodiamine. HClof synaptic responses evoked in the CA1 region of rat hippocampal slices

scientific article published in March 2003

Longitudinal profiling of oligomeric Aβ in human nasal discharge reflecting cognitive decline in probable Alzheimer's disease

scientific article published on 08 July 2020

Mefenamic acid shows neuroprotective effects and improves cognitive impairment in in vitro and in vivo Alzheimer's disease models

scientific article

Methylparaben protects 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells and improved behavioral impairments in mouse model of Parkinson's disease ⬇️

scientific article published on October 12, 2012

Minocycline and neurodegenerative diseases

scientific article published on 11 October 2008

Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models

scientific article

Molecular mechanisms underlying cyclic AMP inhibition of macrophage dependent TNF-alpha production and neurotoxicity in response to amyloidogenic C-terminal fragment of Alzheimer's amyloid precursor protein

scientific article

Multifunctional nanosystems at the interface of physical and life sciences

scholarly article by Won Hyuk Suh et al published February 2009 in Nano Today

Nanotechnology, nanotoxicology, and neuroscience

scientific article

Norepinephrine differentially modulates the innate inflammatory response provoked by amyloid-β peptide via action at β-adrenoceptors and activation of cAMP/PKA pathway in human THP-1 macrophages ⬇️

scientific article published on May 15, 2012

Novel cognitive improving and neuroprotective activities of Polygala tenuifolia Willdenow extract, BT-11.

scientific article published in November 2002

Novel sulphur-rich BODIPY systems that enable stepwise fluorescent O-atom turn-on and H2O2 neuronal system probing.

scientific article published on 14 June 2012

P53 mediates ceramide-induced apoptosis in SKN-SH cells

scientific article published on 01 March 2002

Pathophysiological roles of amyloidogenic carboxy-terminal fragments of the beta-amyloid precursor protein in Alzheimer's disease

scientific article

Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration

scientific article

Phosphorylation of α-synuclein is crucial in compensating for proteasomal dysfunction ⬇️

scientific article published on July 7, 2012

Plasma soluble neuregulin-1 as a diagnostic biomarker for Alzheimer's disease

scientific article published on 28 April 2016

Porous carbon produced in air: physicochemical properties and stem cell engineering

scientific article published on 21 April 2011

Possible roles of amyloid intracellular domain of amyloid precursor protein ⬇️

scientific article published on October 1, 2010

S100A9 Exacerbates the Aβ1-42-mediated Innate Immunity in Human THP-1 Monocytes

scientific article published on 15 August 2016

S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model

scientific article published on 25 February 2014

S100a9 knockdown decreases the memory impairment and the neuropathology in Tg2576 mice, AD animal model

scientific article

SF-6 attenuates 6-hydroxydopamine-induced neurotoxicity: An in vitro and in vivo investigation in experimental models of Parkinson's disease ⬇️

scientific article published on August 8, 2012

SP-8203 reduces oxidative stress via SOD activity and behavioral deficit in cerebral ischemia ⬇️

scientific article published on December 21, 2010

SP-8203 shows neuroprotective effects and improves cognitive impairment in ischemic brain injury through NMDA receptor

scientific article published in August 2011

Selective apoptosis induction in the hippocampal mossy fiber pathway by exposure to CT105, the C-terminal fragment of Alzheimer's amyloid precursor protein

scientific article

Soluble Neuregulin-1 from Microglia Enhances Amyloid Beta-induced Neuronal Death

scientific article

Stem Cell Therapy for Alzheimer's Disease: A Review of Recent Clinical Trials

scientific article

Swedish amyloid precursor protein mutation increases cell cycle-related proteins in vitro and in vivo.

scientific article published in August 2008

Swedish amyloid precursor protein mutation increases phosphorylation of eIF2alpha in vitro and in vivo

scientific article published on May 2007

The Preventive and Therapeutic Effects of Intravenous Human Adipose-Derived Stem Cells in Alzheimer’s Disease Mice ⬇️

scientific article published on September 26, 2012

The Protective Effects of PSM-04 Against Beta Amyloid-Induced Neurotoxicity in Primary Cortical Neurons and an Animal Model of Alzheimer's Disease

scholarly article by Hyunjun Park et al published 2019 in Frontiers in Pharmacology

The Role of S100a9 in the Pathogenesis of Alzheimer’s Disease: The Therapeutic Effects of S100a9 Knockdown or Knockout ⬇️

scientific article published on January 1, 2012

The early synthesis of p35 and activation of CDK5 in LPS-stimulated macrophages suppresses interleukin-10 production.

scientific article published on 24 November 2015

The postnatal environment can counteract prenatal effects on cognitive ability, cell proliferation, and synaptic protein expression

scientific article published on 3 June 2003

The therapeutic effects of human adipose-derived stem cells in Alzheimer's disease mouse models

scientific article published on 23 October 2013

Therapeutic Agents for Alzheimers Disease

Therapeutic Effects of Human Amniotic Epithelial Stem Cells in a Transgenic Mouse Model of Alzheimer's Disease

scientific article published on 10 April 2020

Therapeutic potential of human adipose-derived stem cells in neurological disorders

scientific article

Therapeutic potentials of human adipose-derived stem cells on the mouse model of Parkinson's disease

scientific article published on 24 June 2015

Therapeutic potentials of neural stem cells treated with fluoxetine in Alzheimer's disease.

scientific article published on 3 April 2012

Toxoplasma gondii Infection in the Brain Inhibits Neuronal Degeneration and Learning and Memory Impairments in a Murine Model of Alzheimer's Disease ⬇️

scientific article published on March 21, 2012

Treatment of hypoxic-ischemic encephalopathy in mouse by transplantation of embryonic stem cell-derived cells

scientific article published on 29 April 2007

Vascular Contributions in Alzheimer's Disease-Related Neuropathological Changes: First Autopsy Evidence from a South Asian Aging Population

scientific article published on 2 September 2016

p35 deficiency accelerates HMGB-1-mediated neuronal death in the early stages of an Alzheimer's disease mouse model

scientific article published in October 2013

List of works by Suh Yoo-hun

15-deoxy-Δ¹²,¹⁴ -prostaglandin J₂ inhibits human immunodeficiency virus-1 tat-induced monocyte chemoattractant protein-1/CCL2 production by blocking the extracellular signal-regulated kinase-1/2 signaling pathway independently of peroxisome prolifer

A novel compound, maltolyl p-coumarate, attenuates cognitive deficits and shows neuroprotective effects in vitro and in vivo dementia models.

A novel, selective, and extremely responsive thienyl-based dual fluorogenic probe for tandem superoxide and Hg2+ chemosensing.

Alpha-synuclein induces apoptosis by altered expression in human peripheral lymphocyte in Parkinson's disease

Alpha-synuclein induces migration of BV-2 microglial cells by up-regulation of CD44 and MT1-MMP.

Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway

Alpha-synuclein, Parkinson's disease, and Alzheimer's disease

Amyloid Precursor Protein Binding Protein-1 Is Up-regulated in Brains of Tg2576 Mice ⬇️

Amyloid beta peptide induces cytochrome C release from isolated mitochondria

Amyloid precursor protein binding protein-1 knockdown reduces neuronal differentiation in fetal neural stem cells ⬇️

Amyloid precursor protein binding protein-1 modulates cell cycle progression in fetal neural stem cells

Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

Amyloid-β peptide-induced extracellular S100A9 depletion is associated with decrease of antimicrobial peptide activity in human THP-1 monocytes

An Activity-Regulated microRNA, miR-188, Controls Dendritic Plasticity and Synaptic Transmission by Downregulating Neuropilin-2 ⬇️

BT-11 improves stress-induced memory impairments through increment of glucose utilization and total neural cell adhesion molecule levels in rat brains

BT-11 is effective for enhancing cognitive functions in the elderly humans

Beta-amyloid peptide binding protein does not couple to G protein in a heterologous Xenopus expression system

Biphasic electrical currents stimulation promotes both proliferation and differentiation of fetal neural stem cells

C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression.

Carboxyl-terminal peptide of beta-amyloid precursor protein blocks inositol 1,4,5-trisphosphate-sensitive Ca2+ release in Xenopus laevis oocytes

Cdk5 phosphorylates dopamine D2 receptor and attenuates downstream signaling

Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model

Correction: Biphasic Electrical Currents Stimulation Promotes both Proliferation and Differentiation of Fetal Neural Stem Cells.

Cyclic AMP inhibition of tumor necrosis factor alpha production induced by amyloidogenic C-terminal peptide of Alzheimer's amyloid precursor protein in macrophages: involvement of multiple intracellular pathways and cyclic AMP response element bindi

Cyclin-dependent kinase 5 (Cdk5) regulates the function of CLOCK protein by direct phosphorylation

Cytoskeletal Pathologies of Age-Related Diseases between Elderly Sri Lankan (Colombo) and Indian (Bangalore) Brain Samples

Dehydroevodiamine·HCl Improves Stress-Induced Memory Impairments and Depression Like Behavior in Rats

Dehydroevodiamine·HCl enhances cognitive function in memory-impaired rat models

Dehydroevodiamine•HCl Protects Against Memory Impairment and Cerebral Amyloid-β Production in Tg2576 Mice by Acting as a β-Secretase Inhibitor

Differential functions of NR2A and NR2B in short-term and long-term memory in rats

Differential spatial expression of peripheral olfactory neuron-derived BACE1 induces olfactory impairment by region-specific accumulation of β-amyloid oligomer

Distinct amyloid precursor protein processing machineries of the olfactory system

Dopamine and Cu+/2+ can induce oligomerization of α-synuclein in the absence of oxygen: Two types of oligomerization mechanisms for α-synuclein and related cell toxicity studies

Early stages of Alzheimer's disease are alarming signs in injury deaths caused by traffic accidents in elderly people (≥60 years of age): A neuropathological study

Editorial (Thematic Issue: Molecular and Cellular Engineering Approaches for Neurological Disorders, Diseases, and Injuries Involved the Central and Peripheral Nervous Systems).

Effects of BT-11 on memory in healthy humans

Effects of a Dehydroevodiamine-Derivative on Synaptic Destabilization and Memory Impairment in the 5xFAD, Alzheimer's Disease Mouse Model

Effects of intrahippocampal CT105, a carboxyl terminal fragment of beta-amyloid precursor protein, alone/with inflammatory cytokines on working memory in rats

Effects of the monomeric, oligomeric, and fibrillar Abeta42 peptides on the proliferation and differentiation of adult neural stem cells from subventricular zone

Environmental enrichment compensates for the effects of stress on disease progression in Tg2576 mice, an Alzheimer's disease model

Extremely selective "turn-on" fluorescence detection of hypochlorite confirmed by proof-of-principle neurological studies via esterase action in living cells.

FE65 as a link between VLDLR and APP to regulate their trafficking and processing

Facile "stop codon" method reveals elevated neuronal toxicity by discrete S87p-α-synuclein oligomers

Focal transient ischemia increases APP-BP1 expression in neural progenitor cells ⬇️

General pharmacology of indole [2',3':3,4]pyrido[2,1-b]quinazolinium- 5,7,8,13-tetrahydro-14-methyl-5-oxo-chloride, a new anti-dementia agent

Human adipose-derived stem cells ameliorate repetitive behavior, social deficit and anxiety in a VPA-induced autism mouse model

Huntingtin is localized in the nucleus during preimplanatation embryo development in mice

In vivo imaging of human adipose-derived stem cells in Alzheimer's disease animal model

Increased tau phosphorylation on mitogen-activated protein kinase consensus sites and cognitive decline in transgenic models for Alzheimer's disease and FTDP-17: evidence for distinct molecular processes underlying tau abnormalities

Inhibition of histone deacetylation enhances the neurotoxicity induced by the C-terminal fragments of amyloid precursor protein

Interplay of salicylaldehyde, lysine, and M2+ ions on α-synuclein aggregation: cancellation of aggregation effects and determination of salicylaldehyde neurotoxicity.

Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau

Long-lasting facilitation by dehydroevodiamine. HClof synaptic responses evoked in the CA1 region of rat hippocampal slices

Longitudinal profiling of oligomeric Aβ in human nasal discharge reflecting cognitive decline in probable Alzheimer's disease

Mefenamic acid shows neuroprotective effects and improves cognitive impairment in in vitro and in vivo Alzheimer's disease models

Methylparaben protects 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells and improved behavioral impairments in mouse model of Parkinson's disease ⬇️

Minocycline and neurodegenerative diseases

Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models

Molecular mechanisms underlying cyclic AMP inhibition of macrophage dependent TNF-alpha production and neurotoxicity in response to amyloidogenic C-terminal fragment of Alzheimer's amyloid precursor protein

Multifunctional nanosystems at the interface of physical and life sciences

Nanotechnology, nanotoxicology, and neuroscience

Norepinephrine differentially modulates the innate inflammatory response provoked by amyloid-β peptide via action at β-adrenoceptors and activation of cAMP/PKA pathway in human THP-1 macrophages ⬇️

Novel cognitive improving and neuroprotective activities of Polygala tenuifolia Willdenow extract, BT-11.

Novel sulphur-rich BODIPY systems that enable stepwise fluorescent O-atom turn-on and H2O2 neuronal system probing.

P53 mediates ceramide-induced apoptosis in SKN-SH cells

Pathophysiological roles of amyloidogenic carboxy-terminal fragments of the beta-amyloid precursor protein in Alzheimer's disease

Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration

Phosphorylation of α-synuclein is crucial in compensating for proteasomal dysfunction ⬇️

Plasma soluble neuregulin-1 as a diagnostic biomarker for Alzheimer's disease

Porous carbon produced in air: physicochemical properties and stem cell engineering

Possible roles of amyloid intracellular domain of amyloid precursor protein ⬇️

S100A9 Exacerbates the Aβ1-42-mediated Innate Immunity in Human THP-1 Monocytes

S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model

S100a9 knockdown decreases the memory impairment and the neuropathology in Tg2576 mice, AD animal model

SF-6 attenuates 6-hydroxydopamine-induced neurotoxicity: An in vitro and in vivo investigation in experimental models of Parkinson's disease ⬇️

SP-8203 reduces oxidative stress via SOD activity and behavioral deficit in cerebral ischemia ⬇️

SP-8203 shows neuroprotective effects and improves cognitive impairment in ischemic brain injury through NMDA receptor

Selective apoptosis induction in the hippocampal mossy fiber pathway by exposure to CT105, the C-terminal fragment of Alzheimer's amyloid precursor protein

Soluble Neuregulin-1 from Microglia Enhances Amyloid Beta-induced Neuronal Death