List of works - Ashley Moffett

A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia

scientific article

A critical look at HLA-G.

scientific article published on 04 June 2008

A homodimeric complex of HLA-G on normal trophoblast cells modulates antigen-presenting cells via LILRB1.

scientific article published on July 2007

A microfluidics assay to study invasion of human placental trophoblast cells

scientific article

Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy.

scientific article

BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages

scientific article published on August 2011

Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration

scientific article

Co-evolution of NK receptors and HLA ligands in humans is driven by reproduction

scientific article published on September 2015

Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success ⬇️

scientific article

Composition, Development, and Function of Uterine Innate Lymphoid Cells

scientific article

Development of the human placenta

scientific article published on 27 November 2019

Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy

scientific article published on 20 January 2020

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations

scientific article

Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors

scientific article

Ex vivo functional responses to HLA-G differ between blood and decidual NK cells

scientific article

Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women

scientific article published on 25 November 2020

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C.

scientific article

High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia

scientific article published on 24 September 2018

Human HLA-G+ extravillous trophoblasts: Immune-activating cells that interact with decidual leukocytes.

scientific article published on 26 May 2015

Hypertension persisting after pre-eclampsia: a prospective cohort study at Mulago Hospital, Uganda

scientific article

Immature NK cells, capable of producing IL-22, are present in human uterine mucosa

scientific article published on 27 August 2010

Immunology of placentation in eutherian mammals

scientific article

Influence of HLA-C expression level on HIV control

scientific article published on April 2013

Integrin α2 marks a niche of trophoblast progenitor cells in first trimester human placenta

scientific article published on 14 March 2018

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA-C ligands in a Ugandan population

scientific article published on 24 August 2013

MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling.

scientific article published on 28 February 2014

Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

scientific article published on 02 December 2021

Maternal KIR and fetal HLA-C: a fine balance ⬇️

scientific article published on August 26, 2011

Maternal KIR in combination with paternal HLA-C2 regulate human birth weight

scientific article

Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2.

scientific article

Maternal uterine NK cell-activating receptor KIR2DS1 enhances placentation

scientific article

Menstrual flow as a non-invasive source of endometrial organoids

scientific article published on 17 June 2021

Modulation of Human Leukocyte Antigen-C by Human Cytomegalovirus Stimulates KIR2DS1 Recognition by Natural Killer Cells

scientific article published on 29 March 2017

Molecular characterization of KIR3DL3.

scientific article

NK receptor interactions with MHC class I molecules in pregnancy

scientific article published on 24 July 2008

Natural killer cells, miscarriage, and infertility

scientific article

Natural-killer cell ligands at the maternal-fetal interface: UL-16 binding proteins, MHC class-I chain related molecules, HLA-F and CD48.

scientific article published on 24 July 2008

Nature of allelic sequence polymorphism at the KIR3DL3 locus

scientific article

Paternal MHC expression on mouse trophoblast affects uterine vascularization and fetal growth

scientific article

Pregnancy, parturition and preeclampsia in women of African ancestry

scientific article

Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution

scientific article published on 12 August 2016

Single-cell reconstruction of the early maternal–fetal interface in humans

scientific article published in Nature

The Residual Innate Lymphoid Cells in NFIL3-Deficient Mice Support Suboptimal Maternal Adaptations to Pregnancy.

scientific article published on 19 February 2016

The effect of pregnancy on the uterine NK cell KIR repertoire

scientific article published on 30 August 2011

The role of shed placental DNA in the systemic inflammatory syndrome of preeclampsia

scientific article published on 17 March 2015

The role of the maternal immune system in the regulation of human birthweight

scientific article

Tissue-Specific Education of Decidual NK Cells.

scientific article

Uterine NK cells regulate endometrial bleeding in women and are suppressed by the progesterone receptor modulator asoprisnil

scientific article published on 02 August 2013

Uterine NK cells: active regulators at the maternal-fetal interface.

scientific article published on May 2014

Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution ⬇️

scientific article published on January 21, 2013

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia

scientific article published on 19 June 2017

Variations in killer-cell immunoglobulin-like receptor and human leukocyte antigen genes and immunity to malaria

scientific article published on 15 June 2020

What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast

scientific article published on February 2016

Wide-ranging DNA methylation differences of primary trophoblast cell populations and derived cell lines: implications and opportunities for understanding trophoblast function.

scientific article published on 02 February 2011

List of works by Ashley Moffett

A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia

A critical look at HLA-G.

A homodimeric complex of HLA-G on normal trophoblast cells modulates antigen-presenting cells via LILRB1.

A microfluidics assay to study invasion of human placental trophoblast cells

Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy.

BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages

Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration

Co-evolution of NK receptors and HLA ligands in humans is driven by reproduction

Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success ⬇️

Composition, Development, and Function of Uterine Innate Lymphoid Cells

Development of the human placenta

Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations

Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors

Ex vivo functional responses to HLA-G differ between blood and decidual NK cells

Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C.

High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia

Human HLA-G+ extravillous trophoblasts: Immune-activating cells that interact with decidual leukocytes.

Hypertension persisting after pre-eclampsia: a prospective cohort study at Mulago Hospital, Uganda

Immature NK cells, capable of producing IL-22, are present in human uterine mucosa

Immunology of placentation in eutherian mammals

Influence of HLA-C expression level on HIV control

Integrin α2 marks a niche of trophoblast progenitor cells in first trimester human placenta

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA-C ligands in a Ugandan population

MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling.

Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

Maternal KIR and fetal HLA-C: a fine balance ⬇️

Maternal KIR in combination with paternal HLA-C2 regulate human birth weight

Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2.

Maternal uterine NK cell-activating receptor KIR2DS1 enhances placentation

Menstrual flow as a non-invasive source of endometrial organoids

Modulation of Human Leukocyte Antigen-C by Human Cytomegalovirus Stimulates KIR2DS1 Recognition by Natural Killer Cells

Molecular characterization of KIR3DL3.

NK receptor interactions with MHC class I molecules in pregnancy

Natural killer cells, miscarriage, and infertility

Natural-killer cell ligands at the maternal-fetal interface: UL-16 binding proteins, MHC class-I chain related molecules, HLA-F and CD48.

Nature of allelic sequence polymorphism at the KIR3DL3 locus

Paternal MHC expression on mouse trophoblast affects uterine vascularization and fetal growth

Pregnancy, parturition and preeclampsia in women of African ancestry

Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution

Single-cell reconstruction of the early maternal–fetal interface in humans

The Residual Innate Lymphoid Cells in NFIL3-Deficient Mice Support Suboptimal Maternal Adaptations to Pregnancy.

The effect of pregnancy on the uterine NK cell KIR repertoire

The role of shed placental DNA in the systemic inflammatory syndrome of preeclampsia

The role of the maternal immune system in the regulation of human birthweight

Tissue-Specific Education of Decidual NK Cells.

Uterine NK cells regulate endometrial bleeding in women and are suppressed by the progesterone receptor modulator asoprisnil

Uterine NK cells: active regulators at the maternal-fetal interface.

Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution ⬇️

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia

Variations in killer-cell immunoglobulin-like receptor and human leukocyte antigen genes and immunity to malaria

What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast

Wide-ranging DNA methylation differences of primary trophoblast cell populations and derived cell lines: implications and opportunities for understanding trophoblast function.