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List of works by Helen Blau

5-Azacytidine permits gene activation in a previously noninducible cell type

scientific article

A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles

scientific article published on 14 March 2019

A benchmark for comparison of cell tracking algorithms

scientific article

A brief history of RNAi: the silence of the genes

scientific article published on July 2006

A critical role for AID in the initiation of reprogramming to induced pluripotent stem cells ⬇️

scientific article published on December 4, 2012

A home away from home: challenges and opportunities in engineering in vitro muscle satellite cell niches

scientific article

A method to codetect introduced genes and their products in gene therapy protocols

scientific article

A novel enzyme complementation-based assay for monitoring G-protein-coupled receptor internalization.

scientific article

A robust Pax7EGFP mouse that enables the visualization of dynamic behaviors of muscle stem cells

scientific article published on 24 August 2018

A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal.

scientific article

A universal technology for monitoring G-protein-coupled receptor activation in vitro and noninvasively in live animals.

scientific article

AP-1 is a temporally regulated dual gatekeeper of reprogramming to pluripotency

scientific article

Active tissue-specific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons

scientific article

Adenoviral human BCL-2 transgene expression attenuates early donor cell death after cardiomyoblast transplantation into ischemic rat hearts

scientific article published in July 2006

Adult stem cells and regenerative medicine-a symposium report

scientific article published on 26 October 2019

An In Vitro Model for Identifying Cardiac Side Effects of Anesthetics

scientific article published on 05 September 2018

An immunoreceptor tyrosine-based inhibition motif in varicella-zoster virus glycoprotein B regulates cell fusion and skin pathogenesis ⬇️

scientific article published on January 15, 2013

An objective comparison of cell-tracking algorithms.

scientific article published on 30 October 2017

Anne McLaren (1927-2007).

scientific article published in December 2007

Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies

scientific article

Artificial Stem Cell Niches ⬇️

scientific article published on September 4, 2009

Author Correction: Humanizing the mdx mouse model of DMD: the long and the short of it

scientific article published on 21 December 2020

Beta-enolase is a marker of human myoblast heterogeneity prior to differentiation

scientific article published on June 1, 1992

Bioengineering strategies to accelerate stem cell therapeutics

scientific article published in Nature

Biological progression from adult bone marrow to mononucleate muscle stem cell to multinucleate muscle fiber in response to injury

scientific article published in November 2002

Bone marrow contribution to skeletal muscle: a physiological response to stress

scientific article published in March 2005

Cell therapies for muscular dystrophy

scientific article published on 01 September 2008

Chapter 12 Methods for Myoblast Transplantation ⬇️

scientific article published on January 1, 1997

Collagen matrices enhance survival of transplanted cardiomyoblasts and contribute to functional improvement of ischemic rat hearts.

scientific article published in July 2006

Contribution of hematopoietic stem cells to skeletal muscle

scientific article published on 16 November 2003

Contribution of transplanted bone marrow cells to Purkinje neurons in human adult brains

scientific article

Corrigendum: Dermatologist-level classification of skin cancer with deep neural networks

scientific article published in Nature

Critical role of microenvironmental factors in angiogenesis

scientific article

Cytoplasmic activation of human nuclear genes in stable heterocaryons

scientific article published on April 1983

DNA Demethylation Dynamics ⬇️

scientific article published on September 16, 2011

Defective myoblasts identified in Duchenne muscular dystrophy

scientific article

Dermatologist-level classification of skin cancer with deep neural networks

scientific article

Designing materials to direct stem-cell fate

scientific article

Developmental progression of myosin gene expression in cultured muscle cells

scientific article published in September 1986

Differentiation properties of pure populations of human dystrophic muscle cells

scientific article published on 01 April 1983

Direct evaluation of myocardial viability and stem cell engraftment demonstrates salvage of the injured myocardium

scientific article

Discordant effects of a soluble VEGF receptor on wound healing and angiogenesis

scientific article published in February 2004

Discovery of novel determinants of endothelial lineage using chimeric heterokaryons

scientific article

Early role for IL-6 signalling during generation of induced pluripotent stem cells revealed by heterokaryon RNA-Seq.

scientific article

Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy

article published in the Proceedings of the National Academy of Sciences of the United States of America

Engineering a stem cell house into a home ⬇️

scientific article published on January 31, 2011

Enzymatic detection of protein translocation

scientific article

Epidermal growth factor receptor dimerization monitored in live cells

scientific article published on 01 February 2000

Evidence for defective myoblasts in Duchenne muscular dystrophy.

scientific article published in January 1985

Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation

scientific article

Farewell to Professor David Yaffe - A pillar of the myogenesis field

scientific article published on 18 August 2020

Fast muscle fibers are preferentially affected in Duchenne muscular dystrophy.

scientific article

Fast myosin heavy chains expressed in secondary mammalian muscle fibers at the time of their inception.

scientific article published on September 1994

From marrow to brain: expression of neuronal phenotypes in adult mice.

scientific article

Fusion Competence of Myoblasts Rendered Genetically Null for N-Cadherin in Culture ⬇️

scientific article published on July 28, 1997

Gene delivery to muscle

scientific article published in February 2002

Gene expression and cell fusion analyzed by lacZ complementation in mammalian cells

scientific article published on October 1996

Genetic analysis of alpha 4 integrin functions in the development of mouse skeletal muscle

scientific article

Genetic complementation reveals a novel regulatory role for 3' untranslated regions in growth and differentiation

scientific article published on March 1993

Global linking of cell tracks using the Viterbi algorithm

scientific article

Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function

scientific article published on 01 June 2019

Graded transcriptional response to different concentrations of a single transactivator.

scientific article published on November 1998

Helen Blau: she thinks like a cell. Interview by Ruth Williams

scientific article published in August 2012

Hematopoietic contribution to skeletal muscle regeneration by myelomonocytic precursors

scholarly article

Hepatic parenchymal replacement in mice by transplanted allogeneic hepatocytes is facilitated by bone marrow transplantation and mediated by CD4 cells

scientific article published on 01 February 2008

High-resolution myogenic lineage mapping by single-cell mass cytometry

scientific article published on 17 April 2017

Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity

scientific article published on 18 April 2016

Humanizing the mdx mouse model of DMD: the long and the short of it.

scientific article

IGF-I increases bone marrow contribution to adult skeletal muscle and enhances the fusion of myelomonocytic precursors.

scientific article

Imaging beta-galactosidase activity in vivo using sequential reporter-enzyme luminescence

scientific article

In vivo aging of human fibroblasts does not alter nuclear plasticity in heterokaryons

scientific article

In vivo optical bioluminescence imaging of collagen-supported cardiac cell grafts

scientific article

Increased host neuronal survival and motor function in BMT Parkinsonian mice: involvement of immunosuppression

scientific article

Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M.

scientific article published on 18 April 2018

Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength

scientific article published on 10 December 2020

Injectable biomimetic liquid crystalline scaffolds enhance muscle stem cell transplantation

scientific article

Interaction blues: protein interactions monitored in live mammalian cells by beta-galactosidase complementation.

scientific article

Isolation of human myoblasts with the fluorescence-activated cell sorter

scientific article published in January 1988

Localization of muscle gene products in nuclear domains

scientific article

Localization of muscle gene products in nuclear domains: does this constitute a problem for myoblast therapy?

scientific article published on January 1990

Localization of vascular response to VEGF is not dependent on heparin binding

scientific article published on 26 February 2007

Localized arteriole formation directly adjacent to the site of VEGF-induced angiogenesis in muscle.

scientific article published in April 2003

Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency

scientific article published on 27 March 2017

Luminescent imaging of beta-galactosidase activity in living subjects using sequential reporter-enzyme luminescence

scientific article

Machine learning-based classification of dual fluorescence signals reveals muscle stem cell fate transitions in response to regenerative niche factors

scientific article published in 2023

Macrophages rescue injured engineered muscle

scientific article published on 01 December 2018

MicroRNA programs in normal and aberrant stem and progenitor cells.

scientific article

Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis

scientific article published on February 2004

Microenvironmental VEGF distribution is critical for stable and functional vessel growth in ischemia

scientific article published on 9 November 2006

Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients

scientific article published on 01 December 2019

Modulation of MHC class II antigen expression in human myoblasts after treatment with IFN-gamma

scientific article published on 01 July 1991

Monitoring protein-protein interactions in intact eukaryotic cells by beta-galactosidase complementation

scientific article (publication date: 5 August 1997)

Monitoring protein-protein interactions in live mammalian cells by beta-galactosidase complementation

scientific article

Muscle cell components dictate hepatocyte gene expression and the distribution of the Golgi apparatus in heterokaryons

scientific article published in March 1988

Muscle gene expression in heterokaryons

Muscling toward therapy with ERBB3 and NGFR

scientific article published on 01 January 2018

Myoblast implantation in Duchenne muscular dystrophy: the San Francisco study.

scientific article published in April 1997

Myoblast-mediated expression of colony stimulating factor-1 (CSF-1) in the cytokine-deficient op/op mouse

scientific article published on September 1996

Myoblast-mediated gene transfer for therapeutic angiogenesis

scientific article

Myoblast-mediated gene transfer for therapeutic angiogenesis and arteriogenesis

scientific article published on October 2003

Myoblasts and macrophages share molecular components that contribute to cell-cell fusion

scientific article

Myoblasts in pattern formation and gene therapy

scientific article

NKX3-1 is required for induced pluripotent stem cell reprogramming and can replace OCT4 in mouse and human iPSC induction

Nanogel Star Polymer Architectures: A Nanoparticle Platform for Modular Programmable Macromolecular Self‐Assembly, Intercellular Transport, and Dual‐Mode Cargo Delivery ⬇️

scientific article published on September 8, 2011

Neural cell adhesion molecule (NCAM) and myoblast fusion

scientific article published on May 2000

Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation

scientific article published on 2 July 2007

Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein

scientific article

Noninvasive Tracking of Quiescent and Activated Muscle Stem Cell (MuSC) Engraftment Dynamics In Vivo.

scientific article published in January 2016

Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes.

scientific article

Normal dystrophin transcripts detected in Duchenne muscular dystrophy patients after myoblast transplantation

scientific article

Nuclear reprogramming in heterokaryons is rapid, extensive, and bidirectional

scientific article

Nuclear reprogramming to a pluripotent state by three approaches

scientific article

Nuclear reprogramming: a key to stem cell function in regenerative medicine

scientific article published in September 2004

Objective comparison of particle tracking methods

scientific article

Optimizing techniques for tracking transplanted stem cells in vivo.

scientific article published on 18 August 2005

Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis

scientific article

Perspective for special Gurdon issue for differentiation: can cell fusion inform nuclear reprogramming?

scientific article

Perturbation of single hematopoietic stem cell fates in artificial niches

scientific article

Plasticity of the differentiated state

scientific article

Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy

scientific article published on June 1994

Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength

scientific article

Protein-engineered biomaterials to generate human skeletal muscle mimics.

scientific article published on 5 September 2012

Protein-protein interactions monitored in mammalian cells via complementation of beta -lactamase enzyme fragments

scientific article

Publisher Correction: High-resolution myogenic lineage mapping by single-cell mass cytometry

scientific article published on 5 March 2018

Purification and proliferation of human myoblasts isolated with fluorescence activated cell sorting

scientific article published on 01 January 1990

RIP2, a checkpoint in myogenic differentiation

scientific article

Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette

scientific article (publication date: 28 May 1996)

Recent advances in inducible gene expression systems

scientific article published on 01 October 1998

Redefining differentiation: Reshaping our ends ⬇️

scientific article published on May 30, 2012

Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium

scientific article published on 29 May 2008

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

scientific article

Reprogramming cell differentiation in the absence of DNA synthesis

scientific article

Reprogramming to a muscle fate by fusion recapitulates differentiation

scientific article

Reprogramming towards pluripotency requires AID-dependent DNA demethylation

scientific article

Restriction enzyme-generated siRNA (REGS) vectors and libraries

scientific article published on 4 January 2004

Retroviral lineage markers for assessing myoblast fate in vivo

scientific article published on 01 January 1990

Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice

scientific article published on 2 July 2015

Re“evolutionary” Regenerative Medicine ⬇️

scientific article published on December 21, 2010

Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy

scientific article

Self-renewal and expansion of single transplanted muscle stem cells

scientific article

Short telomeres - A hallmark of heritable cardiomyopathies

scientific article published on 9 February 2018

Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice

scientific article

Significant differences among skeletal muscles in the incorporation of bone marrow-derived cells ⬇️

scientific article published on 01 October 2003

Simultaneous silencing of multiple RB and p53 pathway members induces cell cycle reentry in intact human pancreatic islets

scientific article

Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments.

scientific article

Sir John Gurdon: father of nuclear reprogramming

scientific article

Something in the eye of the beholder

scientific article

Specific T cell receptor gene rearrangements at the site of muscle degeneration in Duchenne muscular dystrophy

article

Spectrophotometric quantitation of tissue culture cell number in any medium

scientific article published on 01 August 1996

Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after bone marrow transplant ⬇️

scientific article (publication date: November 2003)

Stem Cells and Aging: What's Next?

scientific article

Stem Cells in the Treatment of Disease

scientific article published on 01 May 2019

Stem-cell fusion: A twist of fate

scientific article published in Nature

Steroids induce acetylcholine receptors on cultured human muscle: implications for myasthenia gravis

scientific article

Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors

scientific article

Structure–function analysis of varicella-zoster virus glycoprotein H identifies domain-specific roles for fusion and skin tropism ⬇️

scientific article published on October 24, 2011

Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture

scientific article

Systemic delivery of human growth hormone by injection of genetically engineered myoblasts.

scientific article

Tamoxifen treatment ameliorates contractile dysfunction of Duchenne muscular dystrophy stem cell-derived cardiomyocytes on bioengineered substrates

scientific article published on 18 March 2022

Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy

scientific article (publication date: 15 November 2016)

Telomere shortening is a hallmark of genetic cardiomyopathies

article published in the Proceedings of the National Academy of Sciences of the United States of America

Tet B or not tet B: advances in tetracycline-inducible gene expression

scientific article

Tetracycline-regulatable factors with distinct dimerization domains allow reversible growth inhibition by p16.

scientific article published on December 1998

Tetracycline-regulated gene expression following direct gene transfer into mouse skeletal muscle

scientific article published in July 1995

The biological sciences section program at the 60th Annual Meeting of the Gerontological Society of America

scientific article published in April 2008

The central role of muscle stem cells in regenerative failure with aging

scientific article

The clock that controls spine development modelled in a dish

scientific article published on 01 April 2020

The fate of individual myoblasts after transplantation into muscles of DMD patients

scientific article

The fate of myoblasts following transplantation into mature muscle

scientific article published in October 1995

The myoblast defect identified in Duchenne muscular dystrophy is not a primary expression of the DMD mutation. Clonal analysis of myoblasts from five double heterozygotes for two X-linked loci: DMD and G6PD.

scientific article published on September 1986

The well-tempered vessel

scientific article published on 01 May 2001

Therapeutic angiogenesis due to balanced single-vector delivery of VEGF and PDGF-BB.

scientific article

Three slow myosin heavy chains sequentially expressed in developing mammalian skeletal muscle.

scientific article published on July 1993

Tissue Stem Cells: Architects of Their Niches

scientific article published on 01 October 2020

Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions

scientific article

Transcriptional control: rheostat converted to on/off switch

scientific article published in September 2000

Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells

scientific article

Transient immunosuppressive treatment leads to long-term retention of allogeneic myoblasts in hybrid myofibers

scientific article

Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle

scientific article

Transient production of alpha-smooth muscle actin by skeletal myoblasts during differentiation in culture and following intramuscular implantation

scientific article

Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases

scientific article published in February 2013

Tumor suppression by RNA from the 3' untranslated region of alpha-tropomyosin

scientific article published on December 1993

Tumor suppressors: enhancers or suppressors of regeneration? ⬇️

scientific article published on June 1, 2013

Turning terminally differentiated skeletal muscle cells into regenerative progenitors.

scientific article

VEGF gene delivery for treatment of ischemic cardiovascular disease

scientific article

mRNA translation is not a prerequisite for small interfering RNA-mediated mRNA cleavage

scientific article

skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration ⬇️

scientific article published on November 11, 2010

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