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List of works by Frederick M. Ausubel

A Defensin from the Model Beetle Tribolium castaneum Acts Synergistically with Telavancin and Daptomycin against Multidrug Resistant Staphylococcus aureus

scientific article

A High Throughput Amenable Arabidopsis-P. aeruginosa System Reveals a Rewired Regulatory Module and the Utility to Identify Potent Anti-Infectives ⬇️

scientific article published on January 21, 2011

A Methylazanediyl Bisacetamide Derivative Sensitizes Staphylococcus aureus Persisters to a Combination of Gentamicin And Daptomycin

scientific article published in March 2024

A general method for site-directed mutagenesis in prokaryotes ⬇️

scientific article published on January 1, 1981

A high-throughput, near-saturating screen for type III effector genes from Pseudomonas syringae

scientific article

A metasystem of framework model organisms to study emergence of new host-microbe adaptations

scientific article

A peroxidase-dependent apoplastic oxidative burst in cultured Arabidopsis cells functions in MAMP-elicited defense

scientific article published on 7 February 2012

Activation of defense response pathways by OGs and Flg22 elicitors in Arabidopsis seedlings

scientific article

An Antipersister Strategy for Treatment of Chronic Pseudomonas aeruginosa Infections

scientific article published on 18 September 2017

An image analysis toolbox for high-throughput C. elegans assays

scientific article

Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence

scientific journal article

Animal models for host-pathogen interactions

scientific article published on 5 June 2008

Antibacterial properties of 3-(phenylsulfonyl)-2-pyrazinecarbonitrile

scientific article

Antifungal chemical compounds identified using a C. elegans pathogenicity assay

scientific article

Apoplastic peroxidases are required for salicylic acid-mediated defense against Pseudomonas syringae

scientific article published on 2 August 2014

Arabidopsis local resistance to Botrytis cinerea involves salicylic acid and camalexin and requires EDS4 and PAD2, but not SID2, EDS5 or PAD4.

scientific article published in July 2003

Are innate immune signaling pathways in plants and animals conserved?

scientific article

Associations with rhizosphere bacteria can confer an adaptive advantage to plants

scientific article published on 11 May 2015

Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components

scientific article published on 24 May 2010

BifA, a cyclic-Di-GMP phosphodiesterase, inversely regulates biofilm formation and swarming motility by Pseudomonas aeruginosa PA14.

scientific article

Both live and dead Enterococci activate Caenorhabditis elegans host defense via immune and stress pathways

scientific article published on 13 February 2018

Caenorhabditis elegans as a host for the study of host-pathogen interactions

scientific article

Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis

scientific article

Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway

scientific article published in January 2003

Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions

scientific article published in June 2004

Candida albicans Infection of Caenorhabditis elegans Induces Antifungal Immune Defenses ⬇️

scientific article published on June 23, 2011

Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response

scientific article published on April 2004

Chaotic signatures in host-microbe interactions

scientific article published on 14 November 2023

Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal Caenorhabditis elegans/Galleria mellonella Sequential-Screening Approach

scientific article published on 27 July 2020

Characterization of a Francisella tularensis-Caenorhabditis elegans Pathosystem for the Evaluation of Therapeutic Compounds

scientific article published on 26 June 2017

Characterization of the integrated filamentous phage Pf5 and its involvement in small-colony formation

scientific article published on June 2007

Cloning of Rhizobium meliloti nodulation genes by direct complementation of Nod− mutants

scientific article published in Nature

Comparing insertion libraries in two Pseudomonas aeruginosa strains to assess gene essentiality

scientific article

Construction of an Enterococcus faecalis Tn917-mediated-gene-disruption library offers insight into Tn917 insertion patterns

scientific article

Contribution of gelatinase, serine protease, and fsr to the pathogenesis of Enterococcus faecalis endophthalmitis

scientific article

Correction for Kulesekara et al., Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3′-5′)-cyclic-GMP in virulence

scholarly article

Correction: Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay.

scientific article published on 6 April 2010

Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals

scientific article

Cytotoxicity of hydrogen peroxide produced by Enterococcus faecium

scientific article published on August 2004

DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans

scientific article

Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus

scientific article

Enhancing immunity by engineering DAMPs

scientific article published on 24 August 2015

Enterococcus infection biology: lessons from invertebrate host models

scientific article published on March 2014

Erratum: corrigendum: Isochorismate synthase is required to synthesize salicylic acid for plant defence

scientific article published in Nature

Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates

scientific article

Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans

scientific article

Exploiting amoeboid and non-vertebrate animal model systems to study the virulence of human pathogenic fungi

scientific article

FLS2-mediated responses to Ax21-derived peptides: response to the Mueller et al. commentary.

scientific article

Five components of the ethylene-response pathway identified in a screen for weak ethylene-insensitive mutants in Arabidopsis

scholarly article

Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis

scientific article published on July 2005

Genes involved in the evolution of herbivory by a leaf-mining, Drosophilid fly

scientific article (publication date: 2012)

Genome-wide identification of Pseudomonas aeruginosa virulence-related genes using a Caenorhabditis elegans infection model

scientific journal article

Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial

scientific article published on 12 October 2006

Glucosinolate metabolites required for an Arabidopsis innate immune response

scientific article

High-throughput screen for novel antimicrobials using a whole animal infection model

scientific article published on July 2009

High-throughput screening for novel anti-infectives using a C. elegans pathogenesis model

scientific article published on 14 March 2014

Host translational inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an immune response in Caenorhabditis elegans

scientific article published on April 2012

Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection

scholarly article

Identification of Pseudomonas aeruginosa Phenazines that Kill Caenorhabditis elegans ⬇️

scientific article published on January 3, 2013

Identification of an Antimicrobial Agent Effective against Methicillin-Resistant Staphylococcus aureus Persisters Using a Fluorescence-Based Screening Strategy

scientific article

Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay

scientific article

Identification of novel antimicrobials using a live-animal infection model

scientific article published on 26 June 2006

Identification of virulence genes in a pathogenic strain of Pseudomonas aeruginosa by representational difference analysis

scientific article

Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium ⬇️

scientific article published on January 9, 2012

In the Model Host Caenorhabditis elegans, Sphingosine-1-Phosphate-Mediated Signaling Increases Immunity toward Human Opportunistic Bacteria

scientific article published on 22 October 2020

Influence of maternal breast milk ingestion on acquisition of the intestinal microbiome in preterm infants

scientific article published on 30 December 2016

Innate immune responses activated in Arabidopsis roots by microbe-associated molecular patterns

scientific article published on 26 March 2010

Insect-derived cecropins display activity against Acinetobacter baumannii in a whole-animal high-throughput Caenorhabditis elegans model

scientific article

Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase

scholarly article

Intraspecific genetic variation in cytokinin-controlled shoot morphogenesis from tissue explants of Petunia hybrida

Introduction and Historical Overview of DNA Sequencing

Introduction to Gene Editing and Manipulation Using CRISPR/Cas9 Technology

scientific article published on July 2016

Investment in secreted enzymes during nutrient-limited growth is utility dependent

scientific article published on 28 August 2017

Jasmonate signalling in Arabidopsis involves SGT1b-HSP70-HSP90 chaperone complexes

scientific article

Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis

scientific article

Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens

scientific article

MAP kinase signalling cascade in Arabidopsis innate immunity

scientific article published in February 2002

MICROBIOME. Plant microbiome blueprints

scientific article

Mediation of pathogen resistance by exudation of antimicrobials from roots

retracted scientific article

Microsporidia are natural intracellular parasites of the nematode Caenorhabditis elegans

scientific article (publication date: 9 December 2008)

Mining the plant-herbivore interface with a leafmining Drosophila of Arabidopsis

scientific article

Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa

scientific article

Models of Caenorhabditis elegans infection by bacterial and fungal pathogens

scientific article published in January 2008

Mutation of the Glucosinolate Biosynthesis Enzyme Cytochrome P450 83A1 Monooxygenase Increases Camalexin Accumulation and Powdery Mildew Resistance

scientific article published on 2 March 2016

NH125 kills methicillin-resistant Staphylococcus aureus persisters by lipid bilayer disruption

scientific article

Next-Gen Sequencing-Based Mapping and Identification of Ethyl Methanesulfonate-Induced Mutations in Arabidopsis thaliana

scientific article published in October 2014

On the Mechanism of Berberine-INF55 (5-Nitro-2-phenylindole) Hybrid Antibacterials

scientific article

Pathogen-secreted proteases activate a novel plant immune pathway

scientific article published on 2 March 2015

Perception of volatiles produced by UVC-irradiated plants alters the response to viral infection in naïve neighboring plants ⬇️

scientific article published on July 1, 2012

Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance

scientific article published on 2 August 2006

Plant immunity triggered by engineered in vivo release of oligogalacturonides, damage-associated molecular patterns

scientific article published on 13 April 2015

Polymorphic amplified typing sequences provide a novel approach to Escherichia coli O157:H7 strain typing

scientific article

Prevention and control of pests and diseases

scientific article published in January 2006

Prospects for plant-derived antibacterials.

scientific article published in December 2006

Pseudomonas aeruginosa PA14 pathogenesis in Caenorhabditis elegans

scientific article

Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model

scientific article

Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death

scientific article

Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation

scientific article published on April 2002

Pseudomonas syringae enhances herbivory by suppressing the reactive oxygen burst in Arabidopsis

scientific article

Pseudomonas syringae manipulates systemic plant defenses against pathogens and herbivores

scientific article

RESISTANCE TO FUSARIUM OXYSPORUM 1, a dominant Arabidopsis disease-resistance gene, is not race specific

scientific article

RESOLVING CLUSTERED WORMS VIA PROBABILISTIC SHAPE MODELS

scientific article published on June 2010

Regulation of nitrogen metabolism genes by nifA gene product in Klebsiella pneumoniae ⬇️

scientific article published on January 27, 1983

Replication of the Ordered, Nonredundant Library of Pseudomonas aeruginosa strain PA14 Transposon Insertion Mutants

scientific article

Repurposing salicylanilide anthelmintic drugs to combat drug resistant Staphylococcus aureus

scientific article

Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response

scientific article

Resistance to Botrytis cinerea induced in Arabidopsis by elicitors is independent of salicylic acid, ethylene, or jasmonate signaling but requires PHYTOALEXIN DEFICIENT3.

scientific article

Retraction Note: Mediation of pathogen resistance by exudation of antimicrobials from roots ⬇️

scientific article published on March 3, 2011

Rhizosphere-associated Pseudomonas induce systemic resistance to herbivores at the cost of susceptibility to bacterial pathogens

scientific article published on 31 October 2017

Role for beta-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions

scholarly article

Signals involved in Arabidopsis resistance to Trichoplusia ni caterpillars induced by virulent and avirulent strains of the phytopathogen Pseudomonas syringae

scientific article published on June 2002

Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses

scientific article

Staphylococcus aureus virulence factors identified by using a high-throughput Caenorhabditis elegans-killing model

scientific article

Stimulation of host immune defenses by a small molecule protects C. elegans from bacterial infection

scientific article (publication date: 2012)

Strains of Escherichia coli O157:H7 differ primarily by insertions or deletions, not single-nucleotide polymorphisms

scientific article

Tandemly duplicated Arabidopsis genes that encode polygalacturonase-inhibiting proteins are regulated coordinately by different signal transduction pathways in response to fungal infection

scientific article

Temporal global expression data reveal known and novel salicylate-impacted processes and regulators mediating powdery mildew growth and reproduction on Arabidopsis

scientific article

The Apoplastic Oxidative Burst Peroxidase in Arabidopsis Is a Major Component of Pattern-Triggered Immunity ⬇️

scientific article published on January 13, 2012

The Arabidopsis flagellin receptor FLS2 mediates the perception of Xanthomonas Ax21 secreted peptides

scientific article

The AtrbohD-mediated oxidative burst elicited by oligogalacturonides in Arabidopsis is dispensable for the activation of defense responses effective against Botrytis cinerea

scientific article

The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response

scientific article published on 29 April 2004

The Enterococcus faecalis fsrB gene, a key component of the fsr quorum-sensing system, is associated with virulence in the rabbit endophthalmitis model

scientific article

The G protein-coupled receptor FSHR-1 is required for the Caenorhabditis elegans innate immune response

scholarly article

The NBS-LRR architectures of plant R-proteins and metazoan NLRs evolved in independent events

scientific article published on 17 January 2017

The art of serendipity: killing of Caenorhabditis elegans by human pathogens as a model of bacterial and fungal pathogenesis

scientific article published in June 2003

The evolutionarily conserved mediator subunit MDT-15/MED15 links protective innate immune responses and xenobiotic detoxification

scientific article (publication date: May 2014)

The politics of genetic engineering: who decides who's defective?

scientific article published on June 1, 1974

The worm has turned--microbial virulence modeled in Caenorhabditis elegans

scientific article

Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway

scientific article

Twists and turns: my career path and concerns about the future

scientific article published on October 2014

Use of the Galleria mellonella Caterpillar as a Model Host To Study the Role of the Type III Secretion System in Pseudomonas aeruginosa Pathogenesis ⬇️

scientific article published on May 1, 2003

Using PATIMDB to create bacterial transposon insertion mutant libraries

scientific article

Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing locus fsr in Caenorhabditis elegans and mice

scientific article

Virulence profile: Frederick M Ausubel

scientific article

Whole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureus

scientific article (publication date: 2014)

bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans

scientific article

p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans

scientific article

“First Generation” Automated DNA Sequencing Technology ⬇️

scientific article published on October 1, 2011

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