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List of works by Harold F. Dvorak

A multi-gene transcriptional profiling approach to the discovery of cell signature markers ⬇️

scientific article published on October 23, 2010

Anti-VEGF/VEGFR Therapy for Cancer: Reassessing the Target ⬇️

scientific article published on April 15, 2012

Compartmental distribution of tumor-specific monoclonal antibodies in human melanoma xenografts.

scientific article published on April 1994

Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins

scientific article

Discovery of vascular permeability factor (VPF).

scientific article

Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting.

scientific article

Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels

scientific article

Down syndrome candidate region 1 isoform 1 mediates angiogenesis through the calcineurin-NFAT pathway

scientific article

Early Actions of Anti-Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor Receptor Drugs on Angiogenic Blood Vessels

scientific article published on 20 July 2017

Forty-Year Journey of Angiogenesis Translational Research ⬇️

scientific article published on December 21, 2011

Glomeruloid microvascular proliferation follows adenoviral vascular permeability factor/vascular endothelial growth factor-164 gene delivery

scientific article published on March 2001

Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor

scientific article

Heterogeneity of the tumor vasculature

scientific article published on April 2010

Heterogeneity of the tumor vasculature: the need for new tumor blood vessel type-specific targets ⬇️

scientific article published on June 13, 2012

Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules

scientific article

Increased hyaluronan at sites of attachment to mesentery by CD44-positive mouse ovarian and breast tumor cells.

scientific article published on June 1996

Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin

scientific article (publication date: March 2005)

Intracellular distribution of TM4SF1 and internalization of TM4SF1-antibody complex in vascular endothelial cells

scientific article

Neutrophils Emigrate from Venules by a Transendothelial Cell Pathway in Response to FMLP ⬇️

scientific article published on March 16, 1998

Novel Anti-TM4SF1 Antibody-Drug Conjugates with Activity against Tumor Cells and Tumor Vasculature

scientific article

Orphan nuclear receptor TR3/Nur77 regulates VEGF-A-induced angiogenesis through its transcriptional activity

scientific article

Orphan nuclear transcription factor TR3/Nur77 regulates microvessel permeability by targeting endothelial nitric oxide synthase and destabilizing endothelial junctions

scientific article

PGC-1α induces SPP1 to activate macrophages and orchestrate functional angiogenesis in skeletal muscle

scientific article

Pathogenesis of ascites tumor growth: angiogenesis, vascular remodeling, and stroma formation in the peritoneal lining.

scientific article published on January 1995

Pathogenesis of tumor stroma generation: a critical role for leaky blood vessels and fibrin deposition

scientific article published on February 1989

Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.

scientific article published on August 2006

Pathways of macromolecular extravasation across microvascular endothelium in response to VPF/VEGF and other vasoactive mediators

scientific article

Penetration of tumor tissue by antibodies and other immunoproteins

scientific article published on January 1991

Physical nanoscale conduit-mediated communication between tumour cells and the endothelium modulates endothelial phenotype

scientific article

Platelets Exit Venules by a Transcellular Pathway at Sites of F–Met Peptide–Induced Acute Inflammation in Guinea Pigs ⬇️

scientific article published on July 1, 1998

Proteolytic Cleavage of Versican and Involvement of ADAMTS-1 in VEGF-A/VPF-Induced Pathological Angiogenesis ⬇️

scientific article published on March 16, 2011

Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase

scientific article published on 14 May 2009

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

scientific article

Revealing the role of phospholipase Cβ3 in the regulation of VEGF-induced vascular permeability.

scientific article

Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment

scientific article

Rous-Whipple Award Lecture. How tumors make bad blood vessels and stroma

scientific article published on June 2003

Stromal-Based Signatures for the Classification of Gastric Cancer

scientific article

Structure of solid tumors and their vasculature: implications for therapy with monoclonal antibodies

scientific article published on March 1, 1991

T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema

scientific journal article

TM4SF1: a new vascular therapeutic target in cancer

scientific article

TM4SF1: a tetraspanin-like protein necessary for nanopodia formation and endothelial cell migration

scientific article published on 29 May 2011

The L6 protein TM4SF1 is critical for endothelial cell function and tumor angiogenesis

scientific article published on 07 April 2009

The vascular permeabilizing factors histamine and serotonin induce angiogenesis through TR3/Nur77 and subsequently truncate it through thrombospondin-1.

scientific article published on 11 January 2013

Transcellular diapedesis is initiated by invasive podosomes

scientific article

Tumor Stroma, Tumor Blood Vessels, and Antiangiogenesis Therapy

scientific article published on July 2015

Tumor microenvironment and progression

scientific article published on May 2011

Tumor-surrogate blood vessel subtypes exhibit differential susceptibility to anti-VEGF therapy

scientific article published on 21 September 2011

Ultrastructural studies define soluble macromolecular, particulate, and cellular transendothelial cell pathways in venules, lymphatic vessels, and tumor-associated microvessels in man and animals

scientific article

VEGF-A and the induction of pathological angiogenesis

scientific article

VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation

scientific article published on 12 May 2009

VEGF-A(164/165) and PlGF: roles in angiogenesis and arteriogenesis

scientific article

Vascular Hyperpermeability, Angiogenesis, and Stroma Generation ⬇️

scientific article published on February 1, 2012

Vascular Permeability Factor, Fibrin, and the Pathogenesis of Tumor Stroma Formationa ⬇️

scientific article published on December 4, 1992

Vascular permeability and pathological angiogenesis in caveolin-1-null mice

scientific article published on 03 September 2009

Vascular permeability factor (VPF, VEGF) in tumor biology

scientific article

Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis

scientific article

Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy

scientific article

Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine.

scientific article published on January 1997

Vascular permeability factor/vascular endothelial growth factor: an important mediator of angiogenesis in malignancy and inflammation

scientific article published on May 1995

Vascular permeability to plasma, plasma proteins, and cells: an update

scientific article

Vascular permeability, vascular hyperpermeability and angiogenesis

scientific article

Vesiculo-vacuolar organelles and the regulation of venule permeability to macromolecules by vascular permeability factor, histamine, and serotonin

scientific article

Vessel co-option is common in human lung metastases and mediates resistance to anti-angiogenic therapy in preclinical lung metastasis models ⬇️

scientific article

Why are tumour blood vessels abnormal and why is it important to know?

scientific article

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