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List of works by Thomas Szekeres

12(S)-HETE increases intracellular Ca(2+) in lymph-endothelial cells disrupting their barrier function in vitro; stabilization by clinical drugs impairing calcium supply

scientific article published on 4 July 2016

3,3',4,4',5,5'-hexahydroxystilbene impairs melanoma progression in a metastatic mouse model.

scientific article

5-FdUrd-araC heterodinucleoside re-establishes sensitivity in 5-FdUrd- and AraC-resistant MCF-7 breast cancer cells overexpressing ErbB2.

scientific article published in December 2006

A novel N-hydroxy-N'-aminoguanidine derivative inhibits ribonucleotide reductase activity: Effects in human HL-60 promyelocytic leukemia cells and synergism with arabinofuranosylcytosine (Ara-C).

scientific article published on 16 September 2010

A resveratrol analog termed 3,3',4,4',5,5'-hexahydroxy-trans-stilbene is a potent HIV-1 inhibitor

scientific article published on 18 May 2015

Amidox, an inhibitor of ribonucleotide reductase, potentiates the action of Ara-C in HL-60 human promyelocytic leukemia cells

scientific article

An apolar extract of Critonia morifolia inhibits c-Myc, cyclin D1, Cdc25A, Cdc25B, Cdc25C and Akt and induces apoptosis.

scientific article

Analysis of mechanisms contributing to AraC-mediated chemoresistance and re-establishment of drug sensitivity by the novel heterodinucleoside phosphate 5-FdUrd-araC.

scientific article published on March 2006

Antioxidant, prooxidant and cytotoxic activity of hydroxylated resveratrol analogues: structure-activity relationship.

scientific article

Antiproliferative effects of some novel synthetic solanidine analogs on HL-60 human leukemia cells in vitro.

scientific article

Antitumor activity of C-methyl-beta-D-ribofuranosyladenine nucleoside ribonucleotide reductase inhibitors

scientific article published on July 2005

Antitumor activity of resveratrol and its sulfated metabolites against human breast cancer cells

scientific article published on 6 April 2009

Antitumor effects of 3,3',4,4',5,5'-hexahydroxystilbene in HL-60 human promyelocytic leukemia cells.

scientific article published in January 2006

Antitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells.

scientific article published on 8 October 2008

Are allergic reactions to skin clips associated with delayed wound healing?

scientific article published on 01 October 1998

Avemar, a nontoxic fermented wheat germ extract, induces apoptosis and inhibits ribonucleotide reductase in human HL-60 promyelocytic leukemia cells

Bay11-7082 inhibits the disintegration of the lymphendothelial barrier triggered by MCF-7 breast cancer spheroids; the role of ICAM-1 and adhesion

scientific article published on October 23, 2012

Biochemical and antitumor activity of trimidox, a new inhibitor of ribonucleotide reductase

scientific article published on 01 January 1994

Biochemical modulation of Ara-C effects by amidox, an inhibitor of ribonucleotide reductase in HL-60 promyelocytic human leukemia cells

scientific article published in January 2004

Cell cycle dependent regulation of IMP dehydrogenase activity and effect of tiazofurin

scientific article

Chemopreventive effects of resveratrol and resveratrol derivatives

scientific article published on January 2011

Chronic heart failure leads to an expanded plasma volume and pseudoanaemia, but does not lead to a reduction in the body's red cell volume.

scientific article published on 12 August 2008

Clinical pharmacogenetics of immunosuppressive drugs in organ transplantation.

scientific article

Combination chemotherapy of BCNU and Didox acts synergystically in 9L glioma cells

scientific article

Combination effects of digalloylresveratrol with arabinofuranosylcytosine and difluorodeoxycytidine in human leukemia and pancreatic cancer cells

scientific article

Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin

scientific article

Cyclosporine Metabolism in Patients After Kidney, Bone Marrow, Heart-Lung, and Liver Transplantation in the Early and Late Posttransplant Periods

scientific article published on 01 October 2000

Cytotoxic activity of 3,3',4,4',5,5'-hexahydroxystilbene against breast cancer cells is mediated by induction of p53 and downregulation of mitochondrial superoxide dismutase.

scientific article

Cytotoxic and apoptotic effects of novel heterodinucleoside phosphates consisting of 5-fluorodeoxyuridine and Ara-C in human cancer cell lines

scientific article

Cytotoxic and biochemical effects of 3,3′,4,4′,5,5′-hexahydroxystilbene, a novel resveratrol analog in HL-60 human promyelocytic leukemia cells

scientific article published on 01 October 2006

Cytotoxic effects of a doxorubicin-transferrin conjugate in multidrug-resistant KB cells

scientific article published on 01 February 1996

Cytotoxic effects of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine in cross-resistant H9 human lymphoma cells.

scientific article

Cytotoxicity of a transferrin-adriamycin conjugate to anthracycline-resistant cells

scientific article

Cytotoxicity, differentiating activity and metabolism of tiazofurin in human neuroblastoma cells

scientific article

Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity

scientific article published on 15 May 2010

Digalloylresveratrol, a new phenolic acid derivative induces apoptosis and cell cycle arrest in human HT-29 colon cancer cells

scientific article published on 25 October 2008

Digalloylresveratrol, a novel resveratrol analog inhibits the growth of human pancreatic cancer cells.

scientific article published on 14 August 2013

EC4 European Syllabus for Post-Graduate Training in Clinical Chemistry and Laboratory Medicine: version 3 – 2005

scientific article published on 01 January 2006

Effect of substitution at N″-position of N′-hydroxy-N-amino guanidines on tumor cell growth

scientific article published on 21 June 2012

Effects of neuromuscular electrical stimulation of the knee extensor muscles on muscle soreness and different serum parameters in young male athletes: preliminary data

scientific article

Enhanced effects of adriamycin by combination with a new ribonucleotide reductase inhibitor, trimidox, in murine leukemia

scientific article published on 01 January 1998

Epigallocatechin gallate, ellagic acid, and rosmarinic acid perturb dNTP pools and inhibit de novo DNA synthesis and proliferation of human HL-60 promyelocytic leukemia cells: Synergism with arabinofuranosylcytosine.

scientific article published on 3 December 2014

Expression of sulfotransferases and sulfatases in human breast cancer: impact on resveratrol metabolism

scientific article published on 10 September 2009

Formation of micronuclei and other nuclear anomalies in exfoliated nasal and oral cells: results of a human study with workers in a power plant processing poultry litter

scientific article

Four-year study of cobalt and chromium blood levels in patients managed with two different metal-on-metal total hip replacements

scientific article published on 01 March 2003

Fractionation of an Extract of Pluchea odorata Separates a Property Indicative for the Induction of Cell Plasticity from One That Inhibits a Neoplastic Phenotype.

scientific article published on 13 March 2012

Gallic acid inhibits ribonucleotide reductase and cyclooxygenases in human HL-60 promyelocytic leukemia cells.

scientific article published on 20 February 2006

Growth promotion by homocysteine but not by homocysteic acid: a role for excessive growth in homocystinuria or proliferation in hyperhomocysteinemia?

scientific article published in July 1998

Growth promotion by homocysteine thiolactone and its alpha-alkylated derivative ? A role for excess growth in homocystinurias?

scientific article published on 01 February 1994

Hepatic Glucuronidation of Resveratrol: Interspecies Comparison of Enzyme Kinetic Profiles in Human, Mouse, Rat, and Dog

scientific article published on 22 April 2011

Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells.

scientific article published on 11 February 2011

Hsp90 stabilizes Cdc25A and counteracts heat shock-mediated Cdc25A degradation and cell-cycle attenuation in pancreatic carcinoma cells

scientific journal article

Human heart-type fatty-acid-binding protein as a point-of-care test in the early diagnosis of acute myocardial infarction

scientific article published on 08 March 2007

Impact of spinach consumption on DNA stability in peripheral lymphocytes and on biochemical blood parameters: results of a human intervention trial

scientific article published on 09 March 2011

Impact of xanthohumol (a prenylated flavonoid from hops) on DNA stability and other health-related biochemical parameters: Results of human intervention trials

scientific article published on 3 February 2016

In vitro anti-leukemic activity of the ethno-pharmacological plant Scutellaria orientalis ssp. carica endemic to western Turkey.

scientific article

In vitro characterisation of the anti-intravasative properties of the marine product heteronemin.

scientific article published on 30 March 2013

In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen.

scientific article published on 8 January 2013

In-vitro sulfation of piceatannol by human liver cytosol and recombinant sulfotransferases

scientific article published in February 2009

Increased transport of resveratrol across monolayers of the human intestinal Caco-2 cells is mediated by inhibition and saturation of metabolites

scientific article published on 9 August 2006

Inhibition of tumour spheroid-induced prometastatic intravasation gates in the lymph endothelial cell barrier by carbamazepine: drug testing in a 3D model

scientific article published on 19 December 2013

Inorganic phosphate and FGF-23 predict outcome in stable systolic heart failure

scientific article published on 13 December 2011

Intake of a resveratrol-containing dietary supplement has no impact on DNA stability in healthy subjects

scientific article published on 5 September 2012

Interplay between metabolism and transport of resveratrol

scientific article published on July 2013

Investigation of the Antiproliferative Properties of Natural Sesquiterpenes from Artemisia asiatica and Onopordum acanthium on HL-60 Cells in Vitro.

scientific article

Lobatin B inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation

scientific article published on 15 November 2014

Low-dose aspirin does not lowerin vivoplatelet activation in healthy smokers

article

Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside

scientific article published in February 2002

Metabolism and Disposition of Resveratrol in the Isolated Perfused Rat Liver: Role of Mrp2 in the Biliary Excretion of Glucuronides

scientific article published on 01 April 2008

Metabolism and disposition of the novel antileukaemic drug, benzamide riboside, in the isolated perfused rat liver

scientific article published in October 2001

Metabolism of resveratrol in breast cancer cell lines: impact of sulfotransferase 1A1 expression on cell growth inhibition.

scientific article published on 20 December 2007

Metabolomic analysis of resveratrol-induced effects in the human breast cancer cell lines MCF-7 and MDA-MB-231.

scientific article published on 17 January 2011

Methanol extract of the ethnopharmaceutical remedy Smilax spinosa exhibits anti-neoplastic activity

scientific article

Mode of delivery is associated with maternal and fetal endocrine stress response

scientific article published on 20 February 2006

Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro

scientific article

N-terminal pro-B-type natriuretic peptide is an independent predictor of outcome in an unselected cohort of critically ill patients*

scientific article published on 01 October 2007

NT-proBNP is increased in healthy pregnancies compared to non-pregnant controls.

scientific article published on January 2009

New targets and drugs in cancer chemotherapy.

scientific article

Performance Evaluation of the Sysmex XE-5000 Hematology Analyzer for White Blood Cell Analysis in Cerebrospinal Fluid

article

Potentiation of the activity of cisplatin and cyclophosphamide by trimidox, a novel ribonucleotide reductase inhibitor, in leukemia-bearing mice

scientific article published in February 2006

Pro- and anticarcinogenic mechanisms of piceatannol are activated dose dependently in MCF-7 breast cancer cells.

scientific article

Recent developments in cancer chemotherapy oriented towards new targets.

scientific article

Regulation of GTP biosynthesis

scientific article

Regulation of deoxycytidine kinase activity and inhibition by DFDC

scientific article published on 01 January 1993

Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationship

scientific article published in November 2004

Resveratrol and its analogs: defense against cancer, coronary disease and neurodegenerative maladies or just a fad?

scientific article published on 17 August 2007

Resveratrol and its major sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): impact on growth of ZR-75-1 breast cancer cells

scientific article

Resveratrol and resveratrol analogues--structure-activity relationship

scientific article published on 16 March 2010

Resveratrol, an ingredient of wine, acts synergistically with Ara-C and tiazofurin in HL-60 human promyelocytic leukemia cells

scientific article published in January 2006

Ribonucleotide reductase as one important target of [Tris(1,10-phenanthroline)lanthanum(III)] trithiocyanate (KP772).

scientific article

Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N6-substituted 3'-C-methyladenosine derivatives.

scientific article

Sensitizing human colon carcinoma HT-29 cells to cisplatin by cyclopentenylcytosine, in vitro and in vivo

article

Simultaneous determination of the new anticancer agent amidox and its metabolites in rat bile and plasma by high-performance liquid chromatography

scientific article published on August 29, 1997

Sodium butyrate inhibits c-myc splicing and interferes with signal transduction in ovarian carcinoma cells

scientific article published on May 1995

Studies on the antitumor activity and biochemical actions of cyclopentenyl cytosine against human colon carcinoma HT-29 in vitro and in vivo

scientific article published on 01 January 1999

Sulfation of resveratrol in human liver: evidence of a major role for the sulfotransferases SULT1A1 and SULT1E1.

scientific article published in December 2005

Synergistic action of resveratrol, an ingredient of wine, with Ara-C and tiazofurin in HL-60 human promyelocytic leukemia cells.

scientific article published in March 2005

Synergistic action of tiazofurin with hypoxanthine and allopurinol in human neuroectodermal tumor cell lines

scientific article published on December 1993

Synergistic effects of deuterium oxide and gemcitabine in human pancreatic cancer cell lines

scientific article published on 26 November 2007

The EC4 European Syllabus for Post-Graduate Training in Clinical Chemistry and Laboratory Medicine: version 4 – 2012

scientific article published on 01 August 2012

The European Register of Specialists in Clinical Chemistry and Laboratory Medicine: guide to the Register, version 3-2010.

scientific article published in July 2010

The germacranolide sesquiterpene lactone neurolenin B of the medicinal plant Neurolaena lobata (L.) R.Br. ex Cass inhibits NPM/ALK-driven cell expansion and NF-κB-driven tumour intravasation

scientific article published on 26 June 2015

The new inhibitors of ribonucleotide reductase—comparison of some physico-chemical properties

scientific article published on 01 April 1997

Trimidox, an inhibitor of ribonucleotide reductase, induces apoptosis and activates caspases in HL-60 promyelocytic leukemia cells

article

Trimidox, an inhibitor of ribonucleotide reductase, synergistically enhances the inhibition of colony formation by Ara-C in HL-60 human promyelocytic leukemia cells

scientific article published in August 2002

Vemurafenib resistance signature by proteome analysis offers new strategies and rational therapeutic concepts.

scientific article

What is new for an old molecule? Systematic review and recommendations on the use of resveratrol

scientific article

Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis

scientific article published on 17 March 2013

cobas 8000 Modular analyzer series evaluated under routine-like conditions at 14 sites in Australia, Europe, and the United States

scientific article