List of works - Hans-Dieter Klenk

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

scientific article (publication date: 15 May 2003)

Human and avian influenza viruses target different cell types in cultures of human airway epithelium

scientific article

The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host

scientific article

Activation of influenza A viruses by trypsin treatment

scientific article published on December 1, 1975

Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160

scientific article published on November 26, 1992

Proteolytic cleavage of the viral glycoproteins and its significance for the virulence of Newcastle disease virus

scientific article published on July 15, 1976

Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses

scientific article

Functional balance between haemagglutinin and neuraminidase in influenza virus infections

scientific article

The Ebola virus VP35 protein functions as a type I IFN antagonist.

scientific article

Neuraminidase is important for the initiation of influenza virus infection in human airway epithelium

scientific article

Processing of the Ebola virus glycoprotein by the proprotein convertase furin

scientific article published on May 12, 1998

The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.

scientific article

New low-viscosity overlay medium for viral plaque assays

scientific article

Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease

scientific article published on July 1992

Host cell proteases controlling virus pathogenicity

scientific article published on February 1994

Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems

scientific article

Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus

scientific article

SARS--beginning to understand a new virus

scientific article published on December 2003

Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses

scientific article

Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium

scientific article

The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P.

scientific article

GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases

scientific article published on December 1995

Recovery of infectious Ebola virus from complementary DNA: RNA editing of the GP gene and viral cytotoxicity

scholarly article

Overexpression of the alpha-2,6-sialyltransferase in MDCK cells increases influenza virus sensitivity to neuraminidase inhibitors

scientific article

Proteolytic cleavage of influenza virus hemagglutinins: primary structure of the connecting peptide between HA1 and HA2 determines proteolytic cleavability and pathogenicity of Avian influenza viruses

scientific article published in September 1981

Ebola virus: from discovery to vaccine

scientific article

Influenza virus proteins. I. Analysis of polypeptides of the virion and identification of spike glycoproteins

scientific article published in December 1970

Lassa virus Z protein is a matrix protein and sufficient for the release of virus-like particles [corrected].

scientific article

The molecular biology of influenza virus pathogenicity

scientific article published on January 1988

Altered receptor specificity and cell tropism of D222G hemagglutinin mutants isolated from fatal cases of pandemic A(H1N1) 2009 influenza virus

scientific article

Role of Staphylococcus protease in the development of influenza pneumonia

scientific article published in Nature

Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus

scientific article

The structure of the hemagglutinin, a determinant for the pathogenicity of influenza viruses

scientific article published on May 1, 1979

Influenza viruses cause hemolysis and fusion of cells

scientific article published on 01 April 1981

Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin

scientific article

Interdependence of hemagglutinin glycosylation and neuraminidase as regulators of influenza virus growth: a study by reverse genetics

scientific article published on July 2000

Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced virulence

scientific article

Influenza C virus uses 9-O-acetyl-N-acetylneuraminic acid as a high affinity receptor determinant for attachment to cells

scientific article published in May 1986

Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones

scientific article published on January 1994

Infection and activation of monocytes by Marburg and Ebola viruses

scientific article published on November 2001

The receptor-destroying enzyme of influenza C virus is neuraminate-O-acetylesterase.

scientific article published on June 1985

Three of the Four Nucleocapsid Proteins of Marburg Virus, NP, VP35, and L, Are Sufficient To Mediate Replication and Transcription of Marburg Virus-Specific Monocistronic Minigenomes

scientific article published on November 1, 1998

Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation

scientific article published on December 1994

Interactions of Marburg Virus Nucleocapsid Proteins

scientific article published on September 30, 1998

Regulation of receptor binding affinity of influenza virus hemagglutinin by its carbohydrate moiety

scientific article published on November 1, 1997

Cleavage of Influenza Virus Hemagglutinin by Airway Proteases TMPRSS2 and HAT Differs in Subcellular Localization and Susceptibility to Protease Inhibitors

scientific article published on March 17, 2010

Inhibition of glycoprotein biosynthesis of influenza virus by D-glucosamine and 2-deoxy-D-glucose

scientific article published in September 1972

Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor

scientific article published on 10 October 2003

Crystal structure of the matrix protein VP40 from Ebola virus

scientific article

The oligosaccharides of influenza virus hemagglutinin expressed in insect cells by a baculovirus vector

scientific article published on February 1990

List of works by Hans-Dieter Klenk

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

Human and avian influenza viruses target different cell types in cultures of human airway epithelium

The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host

Activation of influenza A viruses by trypsin treatment

Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160

Proteolytic cleavage of the viral glycoproteins and its significance for the virulence of Newcastle disease virus

Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses

Functional balance between haemagglutinin and neuraminidase in influenza virus infections

The Ebola virus VP35 protein functions as a type I IFN antagonist.

Neuraminidase is important for the initiation of influenza virus infection in human airway epithelium

Processing of the Ebola virus glycoprotein by the proprotein convertase furin

The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.

New low-viscosity overlay medium for viral plaque assays

Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease

Host cell proteases controlling virus pathogenicity

Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems

Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus

SARS--beginning to understand a new virus

Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses

Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium

The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P.

GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases

Recovery of infectious Ebola virus from complementary DNA: RNA editing of the GP gene and viral cytotoxicity

Overexpression of the alpha-2,6-sialyltransferase in MDCK cells increases influenza virus sensitivity to neuraminidase inhibitors

Proteolytic cleavage of influenza virus hemagglutinins: primary structure of the connecting peptide between HA1 and HA2 determines proteolytic cleavability and pathogenicity of Avian influenza viruses

Ebola virus: from discovery to vaccine

Influenza virus proteins. I. Analysis of polypeptides of the virion and identification of spike glycoproteins

Lassa virus Z protein is a matrix protein and sufficient for the release of virus-like particles [corrected].

The molecular biology of influenza virus pathogenicity

Altered receptor specificity and cell tropism of D222G hemagglutinin mutants isolated from fatal cases of pandemic A(H1N1) 2009 influenza virus

Role of Staphylococcus protease in the development of influenza pneumonia

Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus

The structure of the hemagglutinin, a determinant for the pathogenicity of influenza viruses

Influenza viruses cause hemolysis and fusion of cells

Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin

Interdependence of hemagglutinin glycosylation and neuraminidase as regulators of influenza virus growth: a study by reverse genetics

Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced virulence

Influenza C virus uses 9-O-acetyl-N-acetylneuraminic acid as a high affinity receptor determinant for attachment to cells

Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones

Infection and activation of monocytes by Marburg and Ebola viruses

The receptor-destroying enzyme of influenza C virus is neuraminate-O-acetylesterase.

Three of the Four Nucleocapsid Proteins of Marburg Virus, NP, VP35, and L, Are Sufficient To Mediate Replication and Transcription of Marburg Virus-Specific Monocistronic Minigenomes

Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation

Interactions of Marburg Virus Nucleocapsid Proteins

Regulation of receptor binding affinity of influenza virus hemagglutinin by its carbohydrate moiety

Cleavage of Influenza Virus Hemagglutinin by Airway Proteases TMPRSS2 and HAT Differs in Subcellular Localization and Susceptibility to Protease Inhibitors

Inhibition of glycoprotein biosynthesis of influenza virus by D-glucosamine and 2-deoxy-D-glucose

Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor

Crystal structure of the matrix protein VP40 from Ebola virus

The oligosaccharides of influenza virus hemagglutinin expressed in insect cells by a baculovirus vector