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List of works by Hanns Hatt

2-Aminoethoxydiphenyl borate activates the mechanically gated human KCNK channels KCNK 2 (TREK-1), KCNK 4 (TRAAK), and KCNK 10 (TREK-2).

scientific article published on 15 May 2013

3-phosphoinositides modulate cyclic nucleotide signaling in olfactory receptor neurons

scientific article published in February 2002

A novel chloride channel in Drosophila melanogaster is inhibited by protons

scientific article published on 15 February 2005

A potential role of odorant receptor agonists and antagonists in the treatment of infertility and contraception.

scientific article

A specific heat shock protein enhances the expression of mammalian olfactory receptor proteins

scientific article

A synthetic sandalwood odorant induces wound-healing processes in human keratinocytes via the olfactory receptor OR2AT4.

scientific article

Activation and modulation of recombinantly expressed serotonin receptor type 3A by terpenes and pungent substances

scientific article published on 8 October 2015

Activation of an olfactory receptor inhibits proliferation of prostate cancer cells

scientific article

Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis

scientific article

Amiloride derivatives are effective blockers of insect odorant receptors

scientific article

Anterograde transsynaptic tracing in the murine somatosensory system using Pseudorabies virus (PrV): a "live-cell"-tracing tool for analysis of identified neurons in vitro

scientific article published in December 2007

Anti-ganglioside antibodies alter presynaptic release and calcium influx

scientific article

Astringency is a trigeminal sensation that involves the activation of G protein-coupled signaling by phenolic compounds

scientific article published on 9 April 2014

Biochemical Large-Scale Interaction Analysis of Murine Olfactory Receptors and Associated Signaling Proteins with Post-Synaptic Density 95, Drosophila Discs Large, Zona-Occludens 1 (PDZ) Domains

scientific article published on 15 May 2015

Borneol inhibits TRPA1, a proinflammatory and noxious pain-sensing cation channel.

scientific article published in July 2015

Camphor modulates TRPV3 cation channels activity by interacting with critical pore-region cysteine residues

scientific article published in May 2013

Cellular mechanisms of olfactory signal transduction

scientific article published in January 2005

Characterization Of Selective TRPM8 Ligands And Their Structure Activity Response (S.A.R) Relationship ⬇️

scientific article published on January 1, 2010

Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18

scientific article

Characterization of recombinant and native Ih-channels from Apis mellifera

scientific article published on November 2003

Characterization of the Olfactory Receptor OR10H1 in Human Urinary Bladder Cancer.

scientific article published on 16 May 2018

Characterization of the Olfactory Receptors Expressed in Human Spermatozoa

scientific article

Chemosensory Ca2+ dynamics correlate with diverse behavioral phenotypes in human sperm

scientific article

Chemosensory information processing between keratinocytes and trigeminal neurons

scientific article

Chemosensory properties of murine nasal and cutaneous trigeminal neurons identified by viral tracing

scientific article

Comprehensive RNA-Seq expression analysis of sensory ganglia with a focus on ion channels and GPCRs in Trigeminal ganglia

scientific article

Correction: Partial Agonism of Taurine at Gamma-Containing Native and Recombinant GABAA Receptors

scientific article published on 24 October 2013

Deep Sequencing of the Human Retinae Reveals the Expression of Odorant Receptors.

scientific article

Deep sequencing of the murine olfactory receptor neuron transcriptome

scientific article

Deletion of the C-terminal domain of the NR2B subunit alters channel properties and synaptic targeting of N-methyl-D-aspartate receptors in nascent neocortical synapses

scientific article

Direct action and modulating effect of (+)- and (-)-nicotine on ion channels expressed in trigeminal sensory neurons

scientific article published on 7 February 2014

Direct activation of transient receptor potential V1 by nickel ions

scientific article

Does ketamine target olfactory receptors in the brain?

scientific article published on 31 March 2015

Drosophila melanogaster GRD and LCCH3 subunits form heteromultimeric GABA-gated cation channels

scientific article published on 17 May 2004

Dual capacity of a human olfactory receptor

scientific article published in October 2004

Dynamical Binding Modes Determine Agonistic and Antagonistic Ligand Effects in the Prostate-Specific G-Protein Coupled Receptor (PSGR).

scientific article published on 22 November 2017

Evidence for a shape-based recognition of odorants in vivo in the human nose from an analysis of the molecular mechanism of lily-of-the-valley odorants detection in the Lilial and Bourgeonal family using the C/Si/Ge/Sn switch strategy

scientific article published on August 2017

Exposure to Hedione Increases Reciprocity in Humans

scientific article

Expression and distribution of the intermediate filament protein nestin and other stem cell related molecules in the human olfactory epithelium

scientific article

Expression and functionality of TRPV1 in breast cancer cells

scientific article published on 13 December 2016

Expression profile of ectopic olfactory receptors determined by deep sequencing

scientific article

Fragrant dioxane derivatives identify beta1-subunit-containing GABAA receptors

scientific journal article

Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes

scientific article published on 18 May 2016

Functional characterization of Ih-channel splice variants from Apis mellifera

scientific article published on September 2004

G protein-coupled receptor signaling via Src kinase induces endogenous human transient receptor potential vanilloid type 6 (TRPV6) channel activation

scientific article published on 24 February 2011

GABAA receptors involved in sleep and anaesthesia: β1- versus β3-containing assemblies

scientific article published on 7 July 2011

Go α is involved in sugar perception in Drosophila

scientific article

Helional induces Ca2+ decrease and serotonin secretion of QGP-1 cells via a PKG-mediated pathway

scientific article published on 23 August 2016

Helional-induced activation of human olfactory receptor 2J3 promotes apoptosis and inhibits proliferation in a non-small-cell lung cancer cell line

scientific article published on 05 December 2016

Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses

scientific article

Human Olfactory Receptors: Novel Cellular Functions Outside of the Nose

scientific article published on 01 July 2018

Human trace amine-associated receptor TAAR5 can be activated by trimethylamine

scientific article published in 2013

Identification of Glycyrrhiza as the rikkunshito constituent with the highest antagonistic potential on heterologously expressed 5-HT3A receptors due to the action of flavonoids

scientific article published on 3 July 2015

Identification of RL-TGR, a coreceptor involved in aversive chemical signaling

scientific article

Identification of a Novel Gnao-Mediated Alternate Olfactory Signaling Pathway in Murine OSNs

scientific article published on 29 March 2016

Identification of a testicular odorant receptor mediating human sperm chemotaxis

scientific article

Identification of amino acids involved in histamine potentiation of GABA A receptors

scientific article

Impact of the Usher syndrome on olfaction

scientific article published on 29 November 2015

In vivo monitoring of chemically evoked activity patterns in the rat trigeminal ganglion

scientific article published on 8 October 2013

Inhibition of TRPV1 for the treatment of sensitive skin

scientific article published on November 2010

Investigation of olfactory function in a Panx1 knock out mouse model.

scientific article published on 12 September 2014

Ion transporter NKCC1, modulator of neurogenesis in murine olfactory neurons

scientific article

Isolation, culture optimization and functional characterization of stem cell neurospheres from mouse neonatal olfactory bulb and epithelium

scientific article published on 6 May 2017

Kampo Medicine: Evaluation of the Pharmacological Activity of 121 Herbal Drugs on GABAA and 5-HT3A Receptors

scientific article published on 29 July 2016

Mimicking the olfactory system for the classification of chemical data

scientific article

Modulatory Effects of Sex Steroids Progesterone and Estradiol on Odorant Evoked Responses in Olfactory Receptor Neurons

scientific article

Molecular and cellular basis of human olfaction

scientific article published on December 2004

Molecular and functional characterization of an I(h)-channel from lobster olfactory receptor neurons

scientific article

Molecular evolution of a chordate specific family of G protein-coupled receptors

scientific article

Monoterpene (-)-citronellal affects hepatocarcinoma cell signaling via an olfactory receptor

scientific article published on 13 December 2014

Monoterpenoids induce agonist-specific desensitization of transient receptor potential vanilloid-3 (TRPV3) ion channels

scientific article

Nasal chemosensory-stimulation evoked activity patterns in the rat trigeminal ganglion visualized by in vivo voltage-sensitive dye imaging

scientific article

Neuronal pathways of viral invasion in mice after intranasal inoculation of pseudorabies virus PrV-9112C2 expressing bovine herpesvirus 1 glycoprotein B.

scientific article published in February 2006

New insight into stimulus-induced plasticity of the olfactory epithelium in Mus musculus by quantitative proteomics

scientific article published on 13 March 2008

New insights in endogenous modulation of ligand-gated ion channels: histamine is an inverse agonist at strychnine sensitive glycine receptors

scientific article published on 17 April 2013

Nonivamide, a capsaicin analogue, exhibits anti-inflammatory properties in peripheral blood mononuclear cells and U-937 macrophages

scientific article published on 26 September 2016

Novel function of beta-arrestin2 in the nucleus of mature spermatozoa

scientific article

OR2H2 regulates the differentiation of human myoblast cells by its ligand aldehyde 13-13.

scientific article published on 17 March 2018

Odorant Receptor 51E2 Agonist β-ionone Regulates RPE Cell Migration and Proliferation

scientific article published on 30 November 2017

Odorant receptor heterodimerization in the olfactory system of Drosophila melanogaster.

scientific article

Odorant receptors and olfactory-like signaling mechanisms in mammalian sperm

scientific article

Odorant-dependent generation of nitric oxide in Mammalian olfactory sensory neurons

scientific article

Odorant-receptor interactions and odor percept: a chemical perspective

scientific article

Olfaction in three genetic and two MPTP-induced Parkinson's disease mouse models

scientific article

Olfactory Receptors Modulate Physiological Processes in Human Airway Smooth Muscle Cells

scientific article published on 4 August 2016

Olfactory Receptors as Biomarkers in Human Breast Carcinoma Tissues.

scientific article

Olfactory receptor OR2AT4 regulates human hair growth

scientific article published in Nature Communications

Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1

scientific article

Olfactory signaling components and olfactory receptors are expressed in tubule cells of the human kidney

scientific article published on 28 September 2016

Oncolytic designer host defense peptide suppresses growth of human liposarcoma ⬇️

scientific article published on November 23, 2010

Partial agonism of taurine at gamma-containing native and recombinant GABAA receptors

scientific article

Particulate adenylate cyclase plays a key role in human sperm olfactory receptor-mediated chemotaxis

scientific article

Peripheral adaptive filtering in human olfaction? Three studies on prevalence and effects of olfactory training in specific anosmia in more than 1600 participants

scientific article published on 12 September 2015

Phosphatidylinositol 3-kinase in the G protein-coupled receptor-induced chemokinesis and chemotaxis of MDA-MB-468 breast carcinoma cells: a comparison with leukocytes

scientific article published on June 2006

Potentiating effect of glabridin from Glycyrrhiza glabra on GABAA receptors

scientific article published on 16 April 2016

Prediction of a Ligand-Binding Niche within a Human Olfactory Receptor by Combining Site-Directed Mutagenesis with Dynamic Homology Modeling

article

Purinergic receptor antagonists inhibit odorant-mediated CREB phosphorylation in sustentacular cells of mouse olfactory epithelium

scientific article

Purinergic signalling mobilizes mitochondrial Ca²⁺ in mouse Sertoli cells

scientific article published on 22 August 2011

RNA-Seq Analysis of Human Trigeminal and Dorsal Root Ganglia with a Focus on Chemoreceptors

scientific article

Reconstitution of a chemical defense signaling pathway in a heterologous system

scientific article

Subunit-specific P2X-receptor expression defines chemosensory properties of trigeminal neurons

scientific article

Supercooling agent icilin blocks a warmth-sensing ion channel TRPV3.

scientific article published in April 2012

Suppression of soft tissue sarcoma growth by a host defense-like lytic peptide

scientific article

The Effect of Pungent and Tingling Compounds from Piper nigrum L. on Background K+ Currents

scientific article published on 26 June 2017

The TRPM8 ion channel comprises direct Gq protein-activating capacity

scientific article published on 30 March 2012

The activation of OR51E1 causes growth suppression of human prostate cancer cells

scientific article published on 21 June 2016

The human olfactory receptor 17-40: requisites for fitting into the binding pocket.

scientific article published on 4 May 2011

The involvement of TRP channels in sensory irritation: a mechanistic approach toward a better understanding of the biological effects of local irritants

scientific article published in April 2016

The pungent substances piperine, capsaicin, 6-gingerol and polygodial inhibit the human two-pore domain potassium channels TASK-1, TASK-3 and TRESK

scientific article

The scaffold protein MUPP1 regulates odorant-mediated signaling in olfactory sensory neurons.

scientific article published on 20 March 2014

Timberol® Inhibits TAAR5-Mediated Responses to Trimethylamine and Influences the Olfactory Threshold in Humans

scientific article

Tmem16b is specifically expressed in the cilia of olfactory sensory neurons.

scientific article published on 25 January 2010

Transcriptome Analysis of Murine Olfactory Sensory Neurons during Development Using Single Cell RNA-Seq

scientific article published on 2 February 2016

Transient receptor potential channel A1 is directly gated by calcium ions

scientific article published on 12 March 2007

Transient receptor potential channels encode volatile chemicals sensed by rat trigeminal ganglion neurons

scientific article published in 2013

Trigeminal ganglion neurons of mice show intracellular chloride accumulation and chloride-dependent amplification of capsaicin-induced responses

scientific article

Two cDNAs coding for histamine-gated ion channels in D. melanogaster

scientific article published in January 2002

Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation

scientific article

Unusual functional properties of homo- and heteromultimeric histamine-gated chloride channels of Drosophila melanogaster: spontaneous currents and dual gating by GABA and histamine

scientific article published in November 2004

Variants of the Drosophila melanogaster Ih-channel are generated by different splicing

scientific article

Voltage- and temperature-dependent activation of TRPV3 channels is potentiated by receptor-mediated PI(4,5)P2 hydrolysis ⬇️

scientific article

[2004 Nobel Prize for Medicine. A good sense of smell for the entire body (interview by Dr. T. Meissner)].

scientific article published in October 2004

hOR17-4 as a potential therapeutic target

scientific article published on April 2004

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