List of works by Eric Kandel

1987 cell-biological interrelationships between short-term and long-term memory

scientific article published in January 1987

3D Neuronal Mitochondrial Morphology in Axons, Dendrites, and Somata of the Aging Mouse Hippocampus

scientific article published on 27 February 2021

5-HT and cAMP induce the formation of coated pits and vesicles and increase the expression of clathrin light chain in sensory neurons of aplysia ⬇️

scientific article published on May 1, 1993

5-Hydroxytryptamine induces a protein kinase A/mitogen-activated protein kinase-mediated and macromolecular synthesis-dependent late phase of long-term potentiation in the amygdala

scientific article published in March 2007

A Behavioral Role for Dendritic Integration

A Behavioral Role for Dendritic Integration

A Common Presynaptic Locus for the Synaptic Changes Underlying Short-term Habituation and Sensitization of the Gill-withdrawal Reflex in Aplysia ⬇️

scientific article published on January 1, 1976

A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neurons

scientific article published in November 2004

A cellular model of memory reconsolidation involves reactivation-induced destabilization and restabilization at the sensorimotor synapse in Aplysia

scientific article

A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia.

scientific article published in December 1986

A family of genes that codes for ELH, a neuropeptide eliciting a stereotyped pattern of behavior in Aplysia

scientific article published in April 1982

A form of long-lasting, learning-related synaptic plasticity in the hippocampus induced by heterosynaptic low-frequency pairing

scientific article published on 7 January 2004

A genetic switch for long-term memory.

scientific article published in February 1998

A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning.

scientific article published in December 1995

A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus

scientific article published on August 2008

A molecular switch for the consolidation of long-term memory: cAMP-inducible gene expression.

scientific article published on June 1995

A morphological and functional study on a cluster of identifiable neurosecretory cells in the abdominal ganglion of aplysia californica

scientific article

A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia

scientific article (publication date: 26 December 2003)

A neuronal isoform of the aplysia CPEB has prion-like properties

scientific article

A new class of noninactivating K+ channels from aplysia capable of contributing to the resting potential and firing patterns of neurons

scientific article published in November 1994

A new component in synaptic plasticity: upregulation of kinesin in the neurons of the gill-withdrawal reflex.

scientific article

A new intellectual framework for psychiatry

scientific article

A novel intermediate stage in the transition between short- and long-term facilitation in the sensory to motor neuron synapse of aplysia.

scientific article published in February 1995

A possible role for the striatum in the pathogenesis of the cognitive symptoms of schizophrenia.

scientific article

A presynaptic role for FMRP during protein synthesis-dependent long-term plasticity in Aplysia.

scientific article

A quantal analysis of the synaptic depression underlying habituation of the gill-withdrawal reflex in Aplysia

scientific article

A quantitative analysis of 2-D gels identifies proteins in which labeling is increased following long-term sensitization in Aplysia.

scientific article published in June 1988

A quantitative study of the Ca2+/calmodulin sensitivity of adenylyl cyclase in Aplysia, Drosophila, and rat

scientific article published on November 1, 1992

A radioautographic analysis in the light and electron microscope of identified Aplysia neurons and their processes after intrasomatic injection of L-(3H)fucose

scientific article

A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity

scientific article

A role in learning for SRF: deletion in the adult forebrain disrupts LTD and the formation of an immediate memory of a novel context

scientific journal article

A semi-persistent adult ocular dominance plasticity in visual cortex is stabilized by activated CREB.

scientific article

A single Aplysia neurotrophin mediates synaptic facilitation via differentially processed isoforms

scientific article

A strategy to capture and characterize the synaptic transcriptome

scientific article published on 15 April 2013

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

scientific article

Acquisition and retention of long-term habituation in Aplysia: correlation of behavioral and cellular processes.

scientific article published in December 1973

Action-potential duration and the modulation of transmitter release from the sensory neurons of Aplysia in presynaptic facilitation and behavioral sensitization

scientific article

Activated CREB is sufficient to overcome inhibitors in myelin and promote spinal axon regeneration in vivo

scientific article published on 01 November 2004

Activation of a heterologously expressed octopamine receptor coupled only to adenylyl cyclase produces all the features of presynaptic facilitation in aplysia sensory neurons

scientific article published on February 2000

Activity-dependent enhancement of presynaptic facilitation provides a cellular mechanism for the temporal specificity of classical conditioning in Aplysia.

scientific article published in November 1994

Activity-dependent enhancement of presynaptic inhibition in Aplysia sensory neurons.

scientific article published in March 1989

Activity-dependent long-term enhancement of transmitter release by presynaptic 3',5'-cyclic GMP in cultured hippocampal neurons.

scientific article published in July 1995

Activity-dependent presynaptic facilitation and hebbian LTP are both required and interact during classical conditioning in Aplysia

scientific article

Additional component in the cellular mechanism of presynaptic facilitation contributes to behavioral dishabituation in Aplysia

scientific article

Adolescent cannabinoid exposure induces irritability-like behavior and cocaine cross-sensitization without affecting the escalation of cocaine self-administration in adulthood

scientific article published in Scientific Reports

Age-related enhancement of a protein synthesis-dependent late phase of LTP induced by low frequency paired-pulse stimulation in hippocampus

scientific article published on May 2006

Altered hippocampal transcript profile accompanies an age-related spatial memory deficit in mice

scientific article

An analysis of dishabituation and sensitization of the gill-withdrawal reflex in Aplysia

scientific article published in August 1971

An analysis of habituation and dishabituation in Aplysia.

scientific article published in January 1970

An animal model of a behavioral intervention for depression

scientific article

An objective evaluation of the beholder's response to abstract and figurative art based on construal level theory

scientific article published on 03 August 2020

Anomalous rectification in the metacerebral giant cells and its consequences for synaptic transmission

scientific article published in March 1966

Anterograde and retrograde signaling by an neurotrophin forms a transsynaptic functional unit

article published in the Proceedings of the National Academy of Sciences of the United States of America

ApCPEB4, a non-prion domain containing homolog of ApCPEB, is involved in the initiation of long-term facilitation

scientific article published on 22 October 2016

Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation.

scientific article

Aplysia CREB2 represses long-term facilitation: relief of repression converts transient facilitation into long-term functional and structural change

scientific article published on December 1995

Are adult learning mechanisms also used for development?

scientific article published on October 9, 1992

Associative Learning in Aplysia: evidence for conditioned fear in an invertebrate

scientific article published in January 1981

Attention enhances the retrieval and stability of visuospatial and olfactory representations in the dorsal hippocampus

scientific article

Autocrine signaling by an neurotrophin forms a presynaptic positive feedback loop

article published in the Proceedings of the National Academy of Sciences of the United States of America

Axonal transport of eukaryotic translation elongation factor 1alpha mRNA couples transcription in the nucleus to long-term facilitation at the synapse

scientific article (publication date: 11 November 2003)

Bidirectional regulation of hippocampal long-term synaptic plasticity and its influence on opposing forms of memory.

scientific article

Biochemical correlates of short-term sensitization in Aplysia: temporal analysis of adenylate cyclase stimulation in a perfused-membrane preparation

scientific article

Biology and the future of psychoanalysis: a new intellectual framework for psychiatry revisited

scientific article

Branch-specific heterosynaptic facilitation in Aplysia siphon sensory cells

scientific article

Brief theta-burst stimulation induces a transcription-dependent late phase of LTP requiring cAMP in area CA1 of the mouse hippocampus

scientific article published in July 1997

C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia

scientific article published in March 1994

CPEB3 inhibits translation of mRNA targets by localizing them to P bodies

scientific article published on 15 August 2019

CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects

scientific article

CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum

scholarly article

CREB1 encodes a nuclear activator, a repressor, and a cytoplasmic modulator that form a regulatory unit critical for long-term facilitation

scientific article

Ca2+/calmodulin sensitivity may be common to all forms of neural adenylate cyclase

scientific article

Calcineurin-mediated LTD of GABAergic inhibition underlies the increased excitability of CA1 neurons associated with LTP.

scientific article published in April 2000

Calcium and the control of synaptic strength by learning ⬇️

scientific article published on October 29, 1981

Cannabinoid Modulation of Eukaryotic Initiation Factors (eIF2α and eIF2B1) and Behavioral Cross-Sensitization to Cocaine in Adolescent Rats.

scientific article published in March 2018

Cannabinoid exposure in rat adolescence reprograms the initial behavioral, molecular, and epigenetic response to cocaine

scientific article published on 20 April 2020

Capture of a protein synthesis-dependent component of long-term depression

scientific article

Capture of the late phase of long-term potentiation within and across the apical and basilar dendritic compartments of CA1 pyramidal neurons: synaptic tagging is compartment restricted.

scientific article published on January 2006

Cell adhesion molecules, CREB, and the formation of new synaptic connections

scientific article published on October 1996

Cell and molecular analysis of long-term sensitization in Aplysia.

scientific article published in January 1986

Cellular Analysis of Long-Term Habituation of the Gill-Withdrawal Reflex of Aplysia californica ⬇️

scientific article published on December 22, 1978

Cellular and integrative properties of the hippocampal pyramidal cell and the comparative electrophysiology of cortical neurons

scientific article published in January 1968

Cellular basis of behavior : an introduction to behavioral neurobiology / Eric R. Kandel. - 1976 ⬇️

book

Cellular insights into behavior and learning / Eric Kandel. - (1979)

scientific article

Cellular mechanisms in the selection and modulation of behavior

scientific article published on December 1, 1979

Cellular neurophysiological approaches in the study of learning

scientific article

Cellular regulation of homeostasis: neuronal control of the circulation in Aplysia.

scientific article

Cellular studies of peripheral neurons in siphon skin of Aplysia californica ⬇️

scientific article published on March 1, 1979

Characterization of cytoplasmic polyadenylation element binding 2 protein expression and its RNA binding activity

scientific article published on 23 December 2014

Characterization of prion-like conformational changes of the neuronal isoform of Aplysia CPEB

scientific article

Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB.

scientific article

Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.

scientific article

Chronic enhancement of CREB activity in the hippocampus interferes with the retrieval of spatial information

scientific article

Chronic nicotine exposure induces a long-lasting and pathway-specific facilitation of LTP in the amygdala

scientific article published on 6 August 2008

Classical Conditioning and Sensitization Share Aspects of the Same Molecular Cascade in Aplysia ⬇️

scientific article published on January 1, 1983

Classical conditioning in Aplysia californica ⬇️

scientific article published on December 1, 1979

Classical conditioning, differential conditioning, and second-order conditioning of the Aplysia gill-withdrawal reflex in a simplified mantle organ preparation.

scientific article published in June 1998

Cognitive neuroscience

scientific article

Cognitive neuroscience

Cognitive neuroscience and the study of memory

scientific article published on March 1998

Common molecular mechanisms in explicit and implicit memory

scientific article

Comparison of the ionic currents modulated during activity-dependent and normal presynaptic facilitation

scientific article published on 15 October 2019

Confocal imaging of cAMP signals in Aplysia neurons.

scientific article

Control of memory formation through regulated expression of a CaMKII transgene

scientific article (publication date: 6 December 1996)

Convergence of small molecule and peptide transmitters on a common molecule cascade

scientific article published on January 1986

Correction to Ward et al. (2015).

scientific article published on August 2015

Correction: Attention Enhances the Retrieval and Stability of Visuospatial and Olfactory Representations in the Dorsal Hippocampus.

scientific article published in October 2010

Correction: Attention Enhances the Retrieval and Stability of Visuospatial and Olfactory Representations in the Dorsal Hippocampus.

scientific article

Cyclic AMP induces functional presynaptic boutons in hippocampal CA3-CA1 neuronal cultures

scientific article published in January 1999

Cyclic adenosine monophosphate in the nervous system of Aplysia californica. I. Increased synthesis in response to synaptic stimulation

scientific article

Cytoplasmic Polyadenylation Element Binding Proteins CPEB1 and CPEB3 Regulate the Translation of FosB and Are Required for Maintaining Addiction-Like Behaviors Induced by Cocaine

scientific article published on 09 July 2020

D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus.

scientific article published on 18 February 2014

D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex.

scientific article

DRD2 C957T polymorphism interacts with the COMT Val158Met polymorphism in human working memory ability.

scientific article

Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo

scientific article published in Nature Communications

Development of a database of amino acid sequences for proteins identified and isolated on two-dimensional polyacrylamide gels

scientific article published on 01 February 1989

Development of neurons in the abdominal ganglion of Aplysia californica. I. Axosomatic synaptic contacts

scientific article published on July 1, 1979

Development of neurons in the abdominal ganglion of Aplysia californica. II. Nonneural support cells

scientific article published on July 1, 1979

Differential classical conditioning of a defensive withdrawal reflex in Aplysia californica.

scientific article published in January 1983

Differential evolutionary rates of neuronal transcriptome in Aplysia kurodai and Aplysia californica as a tool for gene mining

scientific article

Diphasic postsynaptic potential: a chemical synapse capable of mediating conjoint excitation and inhibition

scientific article published on 01 May 1972

Dishabituation in Aplysia can involve either reversal of habituation or superimposed sensitization

scientific article

Dissociation of hedonic reaction to reward and incentive motivation in an animal model of the negative symptoms of schizophrenia

scientific article published on 14 March 2012

Distinct neural signatures for safety and danger in the amygdala and striatum of the mouse

scientific article published in April 2005

Dopamine Regulation of Amygdala Inhibitory Circuits for Expression of Learned Fear

scientific article published on 22 September 2015

Dopamine release from the locus coeruleus to the dorsal hippocampus promotes spatial learning and memory

scientific article published on 07 December 2016

Dscam mediates remodeling of glutamate receptors in Aplysia during de novo and learning-related synapse formation.

scientific article

ERK plays a regulatory role in induction of LTP by theta frequency stimulation and its modulation by beta-adrenergic receptors

scientific article

Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons

scientific article published in June 1993

Electrophysiological properties and functional interconnections of two symmetrical neurosecretory clusters (bag cells) in abdominal ganglion of Aplysia ⬇️

scientific article published on November 1, 1970

Emergence of Posttetanic Potentiation as a Distinct Phase in the Differentiation of an Identified Synapse in Aplysia ⬇️

scientific article published on August 28, 1981

Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS.

scientific article published in July 1994

Enhancement of memory-related long-term facilitation by ApAF, a novel transcription factor that acts downstream from both CREB1 and CREB2.

scientific article

Enkephalin release from VIP interneurons in the hippocampal CA2/3a region mediates heterosynaptic plasticity and social memory

scientific article published on 14 May 2021

Essential role of coiled coils for aggregation and activity of Q/N-rich prions and PolyQ proteins

scientific article published on December 2010

Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic capture

scientific article published in March 2002

FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons

scientific article published in Nature

Facilitatory transmitters and cAMP can modulate accommodation as well as transmitter release in Aplysia sensory neurons: Evidence for parallel processing in a single cell

scientific article published on October 1986

Fear conditioning occludes LTP-induced presynaptic enhancement of synaptic transmission in the cortical pathway to the lateral amygdala

scientific article

From metapsychology to molecular biology: explorations into the nature of anxiety

scientific article

Functional Prions in the Brain

scientific article published on 3 January 2017

Functional role of Tia1/Pub1 and Sup35 prion domains: directing protein synthesis machinery to the tubulin cytoskeleton

scientific article published on 26 June 2014

Further identification of neurons in the abdominal ganglion of Aplysia using behavioral criteria

scientific article published on January 1977

Galpha(i2) inhibition of adenylate cyclase regulates presynaptic activity and unmasks cGMP-dependent long-term depression at Schaffer collateral-CA1 hippocampal synapses

scientific article published on 7 April 2008

Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture.

scientific article

Genes, nerve cells, and the remembrance of things past

scientific article

Genes, synapses, and long-term memory

scientific article published on November 1997

Genetic Perturbation of TIA1 Reveals a Physiological Role in Fear Memory

scientific article published on 01 March 2019

Genetic approaches to memory storage

scientific article

Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory

scientific article published on March 1997

Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation

scientific article

Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors

scientific journal article

Genetic variation in COMT activity impacts learning and dopamine release capacity in the striatum

scientific article published on 17 March 2014

Gpr158 mediates osteocalcin's regulation of cognition

scientific article published on 29 August 2017

Huntingtin is critical both pre- and postsynaptically for long-term learning-related synaptic plasticity in Aplysia

scientific article published in 2014

Identification of a peptide specific for Aplysia sensory neurons by PCR-based differential screening

scientific article published in May 1991

Identification of a serotonin receptor coupled to adenylyl cyclase involved in learning-related heterosynaptic facilitation in Aplysia.

scientific article

Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear

scientific article

Imaging physiologic dysfunction of individual hippocampal subregions in humans and genetically modified mice

scientific article

Imaging terminals of Aplysia sensory neurons demonstrates role of enhanced Ca2+ influx in presynaptic facilitation.

scientific article published in February 1993

Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice.

scientific article

Impaired recruitment of dopamine neurons during working memory in mice with striatal D2 receptor overexpression

scientific article published in Nature Communications

Impaired timing precision produced by striatal D2 receptor overexpression is mediated by cognitive and motivational deficits

scientific article (publication date: August 2009)

Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency

scientific article published in June 1995

Improving temporal cognition by enhancing motivation

scientific article

In Search of Memory

autobiography of Nobel-Prize winning neurologist Eric R. Kandel

In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus

scientific article

In situ hybridization to study the origin and fate of identified neurons

scientific article

Increased attention to spatial context increases both place field stability and spatial memory.

scientific article published in April 2004

Increased dopamine D2 receptor activity in the striatum alters the firing pattern of dopamine neurons in the ventral tegmental area.

scientific article

Increased size and stability of CA1 and CA3 place fields in HCN1 knockout mice

scientific article published on November 2011

Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces

scientific article published in December 2004

Inducible and reversible gene expression with the rtTA system for the study of memory

scientific article published in August 1998

Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins

scientific article

Induction of long-term facilitation in Aplysia sensory neurons by local application of serotonin to remote synapses

scientific article published on December 1993

Inhibition of Rac GTPase triggers a c-Jun- and Bim-dependent mitochondrial apoptotic cascade in cerebellar granule neurons

scientific article

Inhibitor of protein synthesis blocks long-term behavioral sensitization in the isolated gill-withdrawal reflex of Aplysia.

scientific article published in January 1989

Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation

scientific article

Inking in Aplysia californica. I. Neural circuit of an all-or-none behavioral response ⬇️

scientific article published on May 1, 1977

Inking in Aplysia californica. II. Central program for inking ⬇️

scientific article published on May 1, 1977

Inking in Aplysia californica. III. Two different synaptic conductance mechanisms for triggering central program for inking ⬇️

scientific article published on May 1, 1977

Input organization of two symmetrical giant cells in the snail brain

scientific article published in March 1966

Input-specific synaptic plasticity in the amygdala is regulated by neuroligin-1 via postsynaptic NMDA receptors

scientific article

Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure

scientific article published in November 2002

Intrasomatic Injection of Radioactive Precursors for Studying Transmitter Synthesis in Identified Neurons of Aplysia californica ⬇️

scientific article published on December 1, 1973

Ionic mechanisms of excitatory, inhibitory, and dual synaptic actions mediated by an identified interneuron in abdominal ganglion of Aplysia

scientific article published in January 1971

Is contiguity detection in classical conditioning a system or a cellular property? Learning in Aplysia suggests a possible molecular site

scientific article published on April 1988

Is heterosynaptic modulation essential for stabilizing Hebbian plasticity and memory?

scientific article

Is there a cell-biological alphabet for simple forms of learning?

scientific article published on 01 July 1984

Learning to modulate transmitter release: themes and variations in synaptic plasticity

scientific article published on January 1993

Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing

scientific article

Learning-related synaptic growth mediated by internalization of Aplysia cell adhesion molecule is controlled by membrane phosphatidylinositol 4,5-bisphosphate synthetic pathway.

scientific article published in November 2012

Learning-related synaptic plasticity: LTP and LTD ⬇️

scientific article published on June 1, 1991

Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells

scientific article published in Nature

Local protein synthesis and its role in synapse-specific plasticity

scientific article

Long-Term Sensitization of a Defensive Withdrawal Reflex in Aplysia ⬇️

scientific article published on December 7, 1973

Long-lasting forms of synaptic potentiation in the mammalian hippocampus

scientific article

Long-term facilitation in Aplysia involves increase in transmitter release.

scientific article published in January 1988

Long-term facilitation in Aplysia: persistent phosphorylation and structural changes

scientific article published on January 1990

Long-term habituation of a defensive withdrawal reflex in aplysia

scientific article published on 01 January 1972

Long-term heterosynaptic inhibition in Aplysia ⬇️

scientific article published on May 12, 1988

Long-term potentiation is reduced in mice that are doubly mutant in endothelial and neuronal nitric oxide synthase

scientific article published in December 1996

Long-term sensitization training in Aplysia leads to an increase in calreticulin, a major presynaptic calcium-binding protein

scientific article published on December 1, 1992

Long-term sensitization training in Aplysia leads to an increase in the expression of BiP, the major protein chaperon of the ER ⬇️

scientific article published on December 1, 1992

Low-frequency stimulation erases LTP through an NMDA receptor-mediated activation of protein phosphatases

scientific article published in July 1994

Low-frequency stimulation induces a pathway-specific late phase of LTP in the amygdala that is mediated by PKA and dependent on protein synthesis

scientific article published on 12 July 2007

Medial prefrontal lesions in mice impair sustained attention but spare maintenance of information in working memory

scientific article

Medicine. The future of psychiatric research: genomes and neural circuits

scientific article

Memory and behavior: a second generation of genetically modified mice ⬇️

scientific article published on September 1, 1997

Memory suppressor genes: inhibitory constraints on the storage of long-term memory

scientific article published on January 1998

Metamorphosis of Aplysia californica in Laboratory Culture ⬇️

scientific article published on September 1, 1974

Micellar TIA1 with folded RNA binding domains as a model for reversible stress granule formation

scientific article published on 30 November 2020

MicroRNA-22 Gates Long-Term Heterosynaptic Plasticity in Aplysia through Presynaptic Regulation of CPEB and Downstream Targets

scientific article published on 18 June 2015

Modeling cognitive endophenotypes of schizophrenia in mice

scientific article published on 04 May 2009

Modeling motivational deficits in mouse models of schizophrenia: behavior analysis as a guide for neuroscience

scientific article

Modulation of a transient K+ current in the pleural sensory neurons of Aplysia by serotonin and cAMP: implications for spike broadening ⬇️

scientific article published on December 1, 1992

Modulation of an NCAM-related adhesion molecule with long-term synaptic plasticity in Aplysia

scientific article published in May 1992

Molecular Biology of Learning: Modulation of Transmitter Release ⬇️

scientific article published on October 29, 1982

Molecular Mechanisms of the Memory Trace

scientific article published on 31 October 2018

Molecular and structural changes underlying long-term memory storage in Aplysia.

scientific article published on January 1994

Molecular biological approaches to the relationship between short-term and long-term memory in Aplysia.

scientific article published in February 1987

Molecular mechanism for a gateway drug: epigenetic changes initiated by nicotine prime gene expression by cocaine

scientific article

Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48

scientific article

Molecular mechanisms of memory storage in Aplysia

scientific article published on June 2006

Monosynaptic connections made by the sensory neurons of the gill- and siphon-withdrawal reflex in Aplysia participate in the storage of long-term memory for sensitization

scientific article published on December 1985

Nerve Cells and Behavior

scientific article published on July 1, 1970

Neural control of circulation in Aplysia. II. Interneurons

scientific article published in May 1974

Neural science: a century of progress and the mysteries that remain

scientific article

Neural science: a century of progress and the mysteries that remain

scholarly article

Neuralized1 activates CPEB3: a function for nonproteolytic ubiquitin in synaptic plasticity and memory storage

scientific journal article

Neurexin-neuroligin transsynaptic interaction mediates learning-related synaptic remodeling and long-term facilitation in aplysia

scientific article

Neurobiology and molecular biology: the second encounter

scientific article published in January 1983

Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals.

scholarly article

Neuronal Mechanisms of Habituation and Dishabituation of the Gill-Withdrawal Reflex in Aplysia ⬇️

scientific article published on March 27, 1970

Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels.

scientific article

Neuronal transcriptome of Aplysia: neuronal compartments and circuitry

scientific article (publication date: 29 December 2006)

Neuroscience thinks big (and collaboratively).

scientific article published in September 2013

Neuroscience: breaking down scientific barriers to the study of brain and mind

scientific article published in November 2000

Nicotine primes the effect of cocaine on the induction of LTP in the amygdala

scientific article published on 15 April 2013

Nitric oxide acts as a retrograde messenger during long-term potentiation in cultured hippocampal neurons

scientific article published on 01 January 1996

Nitric oxide and cGMP can produce either synaptic depression or potentiation depending on the frequency of presynaptic stimulation in the hippocampus

scientific article published in May 1994

Nitric oxide and carbon monoxide produce activity-dependent long-term synaptic enhancement in hippocampus

scientific article published in June 1993

Nobel laureates' letter to President Bush

Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia.

scientific article

Operant conditioning of gill withdrawal in Aplysia

scientific article published on 01 March 2006

Orbitofrontal cortex mediates the differential impact of signaled-reward probability on discrimination accuracy.

scientific article published on 23 June 2015

Overexpression of an Aplysia shaker K+ channel gene modifies the electrical properties and synaptic efficacy of identified Aplysia neurons ⬇️

scientific article published on February 1, 1992

PKA-activated ApAF-ApC/EBP heterodimer is a key downstream effector of ApCREB and is necessary and sufficient for the consolidation of long-term facilitation

scientific article

PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments

scientific article published on 7 March 2016

Paradoxical influence of hippocampal neurogenesis on working memory

scholarly article

Parallel processing of short-term memory for sensitization in Aplysia

scientific article published on June 1988

Persistent and transcriptionally-dependent increase in protein phosphorylation in long-term facilitation of Aplysia sensory neurons.

scientific article published in May 1989

Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophrenia

scientific article

Pharmacological and genetic approaches to the analysis of tyrosine kinase function in long-term potentiation

scientific article published on January 1, 1992

Physiological and kinetic properties of cholinergic receptors activated by multiaction interneurons in buccal ganglia of Aplysia ⬇️

scientific article published on March 1, 1977

Postsynaptic induction and PKA-dependent expression of LTP in the lateral amygdala

scientific article

Prefrontal cortex HCN1 channels enable intrinsic persistent neural firing and executive memory function

scientific article published on August 2013

Presynaptic Activation of Silent Synapses and Growth of New Synapses Contribute to Intermediate and Long-Term Facilitation in Aplysia ⬇️

scientific article published on September 25, 2003

Presynaptic BDNF required for a presynaptic but not postsynaptic component of LTP at hippocampal CA1-CA3 synapses

scientific article

Presynaptic Facilitation as a Mechanism for Behavioral Sensitization in Aplysia ⬇️

scientific article published on December 10, 1976

Presynaptic and postsynaptic mechanisms of synaptic plasticity and metaplasticity during intermediate-term memory formation in Aplysia.

scientific article

Presynaptic and postsynaptic roles of NO, cGK, and RhoA in long-lasting potentiation and aggregation of synaptic proteins

scientific article published in February 2005

Presynaptic inhibition in Aplysia involves a decrease in the Ca2+ current of the presynaptic neuron ⬇️

scientific article published on February 1, 1980

Presynaptic inhibition produced by an identified presynaptic inhibitory neuron. II. Presynaptic conductance changes caused by histamine

scientific article

Presynaptic membrane potential affects transmitter release in an identified neuron in Aplysia by modulating the Ca 2+ and K + currents ⬇️

scientific article published on January 1, 1980

Presynaptic modulation of voltage-dependent Ca 2+ current: Mechanism for behavioral sensitization in Aplysia californica ⬇️

scientific article published on July 1, 1978

Prior alcohol use enhances vulnerability to compulsive cocaine self-administration by promoting degradation of HDAC4 and HDAC5.

scientific article published in November 2017

Proteins functioning in synaptic transmission at the sensory to motor synapse of Aplysia

scientific article

Psychotherapy and the single synapse. The impact of psychiatric thought on neurobiologic research

scientific article

Quantitative analysis of relative contribution of central and peripheral neurons to gill-withdrawal reflex in Aplysia californica ⬇️

scientific article published on March 1, 1979

Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory

scientific article published on July 2003

Rapid increase in clusters of presynaptic proteins at onset of long-lasting potentiation.

scientific article published on 18 October 2001

RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss

article

Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice.

scientific article published in June 1996

Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization.

scientific article

Relationships between dishabituation, sensitization, and inhibition of the gill- and siphon-withdrawal reflex in Aplysia californica: effects of response measure, test time, and training stimulus.

scientific article published in February 1998

Resolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala

article

Resolving emotional conflict: a role for the rostral anterior cingulate cortex in modulating activity in the amygdala

scientific article published in September 2006

Response

Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory.

scientific article published in January 1998

Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory

scientific article published in April 2002

Role of Aplysia cell adhesion molecules during 5-HT-induced long-term functional and structural changes

scientific article published on 14 July 2004

Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation

scientific article

Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain

scientific article published on 24 October 2016

Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory

scientific article

SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3

scientific journal article

Selective elimination of mRNAs in vivo: complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity ⬇️

scientific article

Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene

scientific journal article

Selective overexpression of dopamine D3 receptors in the striatum disrupts motivation but not cognition.

scientific article

Sensitization in Aplysia: restoration of transmission in synapses inactivated by long-term habituation

scientific article

Sequencing of proteins from two-dimensional gels by using in situ digestion and transfer of peptides to polyvinylidene difluoride membranes: application to proteins associated with sensitization in Aplysia ⬇️

scientific article published on September 1, 1988

Sequencing proteins from acrylamide gels

scientific article published in Nature

Serotonin Induces Structural Plasticity of Both Extrinsic Modulating and Intrinsic Mediating Circuits In Vitro in Aplysia Californica

scientific article published on 01 September 2019

Serotonin and cyclic AMP close single K+ channels in Aplysia sensory neurones.

scientific article published in September 1982

Serotonin increases intracellular Ca2+ transients in voltage-clamped sensory neurons of Aplysia californica

scientific article published on December 1984

Serotonin-induced regulation of the actin network for learning-related synaptic growth requires Cdc42, N-WASP, and PAK in Aplysia sensory neurons

scientific article published in March 2005

Serotonin-mediated endocytosis of apCAM: an early step of learning-related synaptic growth in Aplysia.

scientific article

Sex Differences in Remote Contextual Fear Generalization in Mice

article by Arun Asok et al published 2019 in Frontiers in Behavioral Neuroscience

Short-term modulation of endogenous bursting rhythms by monosynaptic inhibition in Aplysia neurons: effects of contingent stimulation

scientific article published on April 8, 1977

Small systems of neurons / Eric R. Kandel. - (9.1979)

Article from 'Scientific American' published in September 1979

Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase

scientific article

Some principles emerging from the study of short- and long-term memory

scientific article

Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons ⬇️

scientific article published on April 9, 1993

Spontaneous transmitter release is critical for the induction of long-term and intermediate-term facilitation in Aplysia

scientific article

Spontaneous transmitter release recruits postsynaptic mechanisms of long-term and intermediate-term facilitation in Aplysia.

scientific article

Stimulus-response relations and stability of mechanoreceptor and motor neurons mediating defensive gill-withdrawal reflex in Aplysia ⬇️

scientific article published on March 1, 1978

Structural Components of Synaptic Plasticity and Memory Consolidation

scientific article published on July 2015

Structural changes accompanying memory storage

scientific article

Sustained CPEB-dependent local protein synthesis is required to stabilize synaptic growth for persistence of long-term facilitation in Aplysia

scientific article

Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storage

scientific article

Synaptic Facilitation and Behavioral Sensitization in Aplysia : Possible Role of Serotonin and Cyclic AMP ⬇️

scientific article published on December 10, 1976

Synaptic Plasticity and the Modulation of the Ca2+ Current ⬇️

scientific article published on December 1, 1980

Synaptic remodeling, synaptic growth and the storage of long-term memory in Aplysia

scientific article published on January 2008

Synaptic transmission: a bidirectional and self-modifiable form of cell-cell communication

scientific article

Synaptically released zinc gates long-term potentiation in fear conditioning pathways.

scholarly article

TIA-1 Is a Functional Prion-Like Protein.

scientific article published on 21 December 2016

TIA-1 Self-Multimerization, Phase Separation, and Recruitment into Stress Granules Are Dynamically Regulated by Zn2.

scientific article published in January 2018

Target-dependent structural changes accompanying long-term synaptic facilitation in Aplysia neurons

scientific article

Temporal and spatial regulation of the expression of BAD2, a MAP kinase phosphatase, during seizure, kindling, and long-term potentiation

scientific article published on 01 September 1994

The 3'-untranslated region of CaMKII alpha is a cis-acting signal for the localization and translation of mRNA in dendrites

scientific article published on November 1996

The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton.

scientific article

The Class II Histone Deacetylase Hypothesis of Addiction

scientific article published on 22 June 2018

The Functional Organization of Invertebrate Ganglia ⬇️

scientific article

The Neurobiology of Fear Generalization

scientific article published on 01 January 2018

The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3

scientific journal article

The Role of Functional Prion-Like Proteins in the Persistence of Memory

scientific article published on April 2016

The age of the unconscious

book written by: Eric R. Kandel

The contribution of facilitation of monosynaptic PSPs to dishabituation and sensitization of the Aplysia siphon withdrawal reflex.

scientific article published in December 1999

The emergence of modern neuroscience: some implications for neurology and psychiatry

scientific article

The growth cones of Aplysia sensory neurons: Modulation by serotonin of action potential duration and single potassium channel currents

scientific article published on September 1986

The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells

scientific article published in November 2003

The impact of motivation on cognitive performance in an animal model of the negative and cognitive symptoms of schizophrenia.

scientific article published on 27 April 2015

The long and the short of long-term memory--a molecular framework

scientific article published on July 1986

The long-term stability of new hippocampal place fields requires new protein synthesis.

scholarly article

The molecular biology of memory storage: a dialog between genes and synapses

scientific article

The molecular biology of memory storage: a dialogue between genes and synapses

scientific article

The morphology of identified neurons in the abdominal ganglion of Aplysia californica

scientific article published on August 13, 1976

The organization of subpopulations in the abdominal ganglion of Aplysia.

scientific article

The past, the future and the biology of memory storage

scientific article

The persistence of long-term memory: a molecular approach to self-sustaining changes in learning-induced synaptic growth

scientific article

The synaptic actions mediated by the different branches of a single neuron

scientific article

Theta frequency stimulation induces a local form of late phase LTP in the CA1 region of the hippocampus

scientific article

Theta frequency stimulation up-regulates the synaptic strength of the pathway from CA1 to subiculum region of hippocampus

scientific article

Timing as a window on cognition in schizophrenia

scientific article published on 21 April 2011

Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway

scientific article published in October 1998

Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation

scientific article published on February 1993

Toward a neurobiology of psychotherapy: basic science and clinical applications

scientific article

Transcriptional regulation of long-term memory in the marine snail Aplysia

scientific article

Transcriptome analysis and identification of regulators for long-term plasticity in Aplysia kurodai

scholarly article

Transgenic approaches to cognition.

scientific article published on April 1995

Transgenic mice lacking NMDAR-dependent LTD exhibit deficits in behavioral flexibility

scientific article

Transient and selective overexpression of D2 receptors in the striatum causes persistent deficits in conditional associative learning

scholarly article

Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning.

scientific article published in February 2006

Transient expansion of synaptically connected dendritic spines upon induction of hippocampal long-term potentiation.

scientific article

Transient overexpression of striatal D2 receptors impairs operant motivation and interval timing.

scientific article

Two endogenous neuropeptides modulate the gill and siphon withdrawal reflex in Aplysia by presynaptic facilitation involving cAMP-dependent closure of a serotonin-sensitive potassium channel ⬇️

scientific article published on December 1, 1984

Two functional effects of decreased conductance EPSP's: synaptic augmentation and increased electrotonic coupling

scientific article published on April 9, 1976

Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus

scientific article

Ubiquitination and SUMOylation of Amyloid and Amyloid-like Proteins in Health and Disease

scientific article published on 18 August 2019

Ultrastructure of the synapses of sensory neurons that mediate the gill-withdrawal reflex inAplysia ⬇️

scientific article published on August 1, 1979

Using an aplysia two-hybrid system to examine the interactions between transcription factors involved in long-term facilitation in the nervous system of aplysia

scientific article

What Molecular Steps Determine the Time Course of the Memory for Short-term Sensitization in Aplysia? ⬇️

scientific article published on January 1, 1983

What is remembered? Role of attention on the encoding and retrieval of hippocampal representations.

scientific article published on June 2009

Whereas short-term facilitation is presynaptic, intermediate-term facilitation involves both presynaptic and postsynaptic protein kinases and protein synthesis

scientific article published on 18 January 2011

cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase.

scientific article published in October 1994

cAMP evokes long-term facilitation in Aplysia sensory neurons that requires new protein synthesis

scientific article

cAMP response element-binding protein is activated by Ca2+/calmodulin- as well as cAMP-dependent protein kinase ⬇️

scientific article published on June 1, 1991

cAMP response element-binding protein-mediated gene expression increases the intrinsic excitability of CA1 pyramidal neurons.

scientific article

p38 MAP kinase mediates both short-term and long-term synaptic depression in aplysia.

scientific article published in August 2003

stathmin, a gene enriched in the amygdala, controls both learned and innate fear

scientific article

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