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List of works by Gunter Schneider

1.9 Å structure of the signal receiver domain of the putative response regulator NarL fromMycobacterium tuberculosis

scientific article

A flexible lid controls access to the active site in 1,3,8-trihydroxynaphthalene reductase

scientific article published on 01 January 1997

A method for processing diffraction data from twinned protein crystals and its application in the structure determination of an FAD/NADH-binding fragment of nitrate reductase

scientific article

A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity

scientific article published on 21 April 2005

A structural basis for LCMV immune evasion: subversion of H-2D(b) and H-2K(b) presentation of gp33 revealed by comparative crystal structure.Analyses

scientific article

A thiamin diphosphate binding fold revealed by comparison of the crystal structures of transketolase, pyruvate oxidase and pyruvate decarboxylase

article

Aclacinomycin 10-hydroxylase is a novel substrate-assisted hydroxylase requiring S-adenosyl-L-methionine as cofactor

scientific article published on 17 November 2004

Aclacinomycin oxidoreductase (AknOx) from the biosynthetic pathway of the antibiotic aclacinomycin is an unusual flavoenzyme with a dual active site.

scholarly article

Activation of thiamin diphosphate in enzymes ⬇️

scientific article published on June 29, 1998

Active site specific cadmium(II)-substituted horse liver alcohol dehydrogenase: crystal structures of the free enzyme, its binary complex with NADH, and the ternary complex with NADH and bound p-bromobenzyl alcohol

scientific article published on 01 December 1985

An idea whose time has come

scientific article

Analysis of an invariant cofactor-protein interaction in thiamin diphosphate-dependent enzymes by site-directed mutagenesis. Glutamic acid 418 in transketolase is essential for catalysis.

scientific article published on December 1994

Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens.

scientific article published on 19 September 2006

Asp477 is a determinant of the enantioselectivity in yeast transketolase

scientific article published on 01 March 1998

Cloning, expression, purification and crystallization of saccharopine reductase from Magnaporthe grisea

scientific article published on May 2000

Comparison of fluorescence and light scattering based methods to assess formation and stability of protein–protein complexes ⬇️

article by Jolanta Kopec & Gunter Schneider published August 2011 in Journal of Structural Biology

Comparison of the crystal structures of L2 and L8S8 Rubisco suggests a functional role for the small subunit.

scientific article

Conservation of structure and mechanism within the transaldolase enzyme family

scientific article

Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis

scientific article

Crystal structure and reactivity of YbdL from Escherichia coli identify a methionine aminotransferase function

scientific article

Crystal structure of 1-deoxy-d-xylulose-5-phosphate reductoisomerase from Zymomonas mobilis at 1.9-A resolution

scientific article published in April 2004

Crystal structure of NirD, the small subunit of the nitrite reductase NirbD from Mycobacterium tuberculosis at 2.0 Å resolution

scientific article

Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products

scientific article

Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism

scientific article

Crystal structure of aclacinomycin-10-hydroxylase, a S-adenosyl-L-methionine-dependent methyltransferase homolog involved in anthracycline biosynthesis in Streptomyces purpurascens

scientific article

Crystal structure of an ATP-dependent carboxylase, dethiobiotin synthetase, at 1.65 A resolution

scientific article

Crystal structure of an arthritogenic anticollagen immune complex

scientific article

Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes

scientific article

Crystal structure of bifunctional aldos-2-ulose dehydratase/isomerase from Phanerochaete chrysosporium with the reaction intermediate ascopyrone M

scientific article

Crystal structure of decameric fructose-6-phosphate aldolase from Escherichia coli reveals inter-subunit helix swapping as a structural basis for assembly differences in the transaldolase family

scientific article

Crystal structure of diaminopelargonic acid synthase: evolutionary relationships between pyridoxal-5'-phosphate-dependent enzymes

scientific article

Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil

scientific article

Crystal structure of nitrile hydratase reveals a novel iron centre in a novel fold

scientific article published on 15 May 1997

Crystal structure of saccharopine reductase from Magnaporthe grisea, an enzyme of the alpha-aminoadipate pathway of lysine biosynthesis

scientific article

Crystal structure of the FAD-containing fragment of corn nitrate reductase at 2.5 A resolution: relationship to other flavoprotein reductases

scientific article

Crystal structure of the active site of ribulose-bisphosphate carboxylase

scientific article published in Nature

Crystal structure of the carbohydrate recognition domain of p58/ERGIC-53, a protein involved in glycoprotein export from the endoplasmic reticulum

scientific article

Crystal structure of the cofactor-independent monooxygenase SnoaB from Streptomyces nogalater: implications for the reaction mechanism

scientific article

Crystal structure of the complex of ribulose-1,5-bisphosphate carboxylase and a transition state analogue, 2-carboxy-D-arabinitol 1,5-bisphosphate

scientific article

Crystal structure of the glycosyltransferase SnogD from the biosynthetic pathway of nogalamycin in Streptomyces nogalater ⬇️

scientific article

Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity

scientific article published on 6 January 2006

Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer

scientific article

Crystal structure of the reduced Schiff-base intermediate complex of transaldolase B from Escherichia coli: mechanistic implications for class I aldolases

scientific article

Crystal structure of the ternary complex of 1,3,8-trihydroxynaphthalene reductase from Magnaporthe grisea with NADPH and an active-site inhibitor

scientific article

Crystal structure of the ternary complex of ribulose-1,5-bisphosphate carboxylase, Mg(II), and activator CO2 at 2.3-A resolution

scientific article

Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid

scientific article (publication date: May 2003)

Crystal structure of transaldolase B from Escherichia coli suggests a circular permutation of the alpha/beta barrel within the class I aldolase family

scientific article

Crystal structure of transketolase in complex with thiamine thiazolone diphosphate, an analogue of the reaction intermediate, at 2.3 Å resolution

scientific article published on 01 July 1993

Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF3-diaminopelargonic acid and enzyme-MgADP-dethiobiotin-phosphate; implications for catalysis

scientific article published on December 1998

Crystal structures of SnoaL2 and AclR: two putative hydroxylases in the biosynthesis of aromatic polyketide antibiotics

scientific article

Crystal structures of mouse class II alcohol dehydrogenase reveal determinants of substrate specificity and catalytic efficiency

scientific article

Crystal structures of rat acid phosphatase complexed with the transition-state analogs vanadate and molybdate. Implications for the reaction mechanism

scientific article

Crystal structures of the active site in specifically metal-depleted and cobalt-substituted horse liver alcohol dehydrogenase derivatives

scientific article

Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis

scientific article

Crystallization and Preliminary X-ray Analysis of Phenol Hydroxylase from Trichosporon cutaneum

Crystallization and preliminary X-ray crystallographic analysis of recombinant transaldolase B from Eschericha coli.

scientific article

Crystallization and preliminary X-ray diffraction studies of aclacinomycin-10-methyl esterase and aclacinomycin-10-hydroxylase from Streptomyces purpurascens

scientific article published on 19 August 2003

Crystallization and preliminary X-ray diffraction study of 1,3,8-trihydroxynaphthalene reductase fromMagnaporthe grisea

scientific article published in April 1996

Crystallization and preliminary X-ray study of pig liver dihydropyrimidine dehydrogenase.

scientific article

Crystallization and preliminary crystallographic data of SnoaL, a polyketide cyclase in nogalamycin biosynthesis

scientific article

Crystallization and preliminary crystallographic studies of the FAD domain of corn NADH: Nitrate reductase

scientific article published on 01 March 1992

Crystallographic refinement and structure of ribulose-1,5-bisphosphate carboxylase from Rhodospirillum rubrum at 1.7 A resolution

scientific article

Crystallography and mutagenesis of transketolase: mechanistic implications for enzymatic thiamin catalysis ⬇️

scientific article published on June 29, 1998

CysK2 from Mycobacterium tuberculosis is an O-phospho-L-serine-dependent S-sulfocysteine synthase

scientific journal article

Cysteine synthase (CysM) of Mycobacterium tuberculosis is an O-phosphoserine sulfhydrylase: evidence for an alternative cysteine biosynthesis pathway in mycobacteria

scientific article

Design of a specific colonic mucus marker using a human commensal bacterium cell surface domain

scientific article published on 16 March 2012

Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.

scientific article published in May 2004

Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-acyl-ACP Reductase from Pseudomonas aeruginosa

scientific article

Discovery of novel inhibitors targeting the Mycobacterium tuberculosis O-acetylserine sulfhydrylase (CysK1) using virtual high-throughput screening

scientific article published on 16 January 2013

Disruption of Escherichia coli transaldolase into catalytically active monomers: evidence against half-of-the-sites mechanism

scientific article published in December 1998

Effect of coenzyme modification on the structural and catalytic properties of wild-type transketolase and of the variant E418A from Saccharomyces cerevisiae.

scientific article

Electrostatic fields at the active site of ribulose-1,5-bisphosphate carboxylase

scientific article published in February 1992

Enzymes in the biosynthesis of aromatic polyketide antibiotics

scientific article

Epitope-specific antibody response is controlled by immunoglobulin V H polymorphisms

scientific article

Eukaryotic expression: developments for structural proteomics.

scientific article published on 19 September 2006

Examination of donor substrate conversion in yeast transketolase

scientific article

Examination of substrate binding in thiamin diphosphate-dependent transketolase by protein crystallography and site-directed mutagenesis

scientific article

Examination of the Thiamin Diphosphate Binding Site in Yeast Transketolase by Site-Directed Mutagenesis

scientific article published on 01 March 1997

Expression, purification and crystallization of the cofactor-independent monooxygenase SnoaB from the nogalamycin biosynthetic pathway

scientific article published on 14 February 2009

Expression, purification, refolding and crystallization of the carbohydrate-recognition domain of p58/ERGIC-53, an animal C-type lectin involved in export of glycoproteins from the endoplasmic reticulum

scientific article published on 21 February 2002

Expression, refolding and crystallization of murine MHC class I H-2Db in complex with human beta2-microglobulin

scientific article published on 24 November 2005

First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value.

scientific article published on 19 September 2006

High resolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylases

scientific article

High-resolution structures of oxidized and reduced thioredoxin reductase from Helicobacter pylori

scientific article

His103 in yeast transketolase is required for substrate recognition and catalysis.

scientific article published in November 1995

How Thiamin Diphosphate Is Activated in Enzymes

scientific article published in Science

Identification of Late-Stage Glycosylation Steps in the Biosynthetic Pathway of the Anthracycline Nogalamycin

scientific article published on 25 November 2011

Identification of catalytically important residues in the active site of Escherichia coli transaldolase

scientific article

Identification of catalytically important residues in yeast transketolase

scientific article

Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum

scientific article

Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate

scientific article

Murine class I major histocompatibility complex H–2Dd: expression, refolding and crystallization

article

NMR analysis of covalent intermediates in thiamin diphosphate enzymes

scientific article published in July 2003

New crystal forms of ribulose-1,5-bisphosphate carboxylase/oxygenase from Rhodospirillum rubrum.

scientific article

Novel tetramer assembly of pyruvate decarboxylase from brewer's yeast observed in a new crystal form

scientific article published on 01 February 1997

Oligomerization properties of ERp29, an endoplasmic reticulum stress protein

scientific journal article

Peptidoglycan remodeling in Mycobacterium tuberculosis: comparison of structures and catalytic activities of RipA and RipB

scientific article

Phosphatase and oxygen radical-generating activities of mammalian purple acid phosphatase are functionally independent

scientific journal article

Preliminary X-ray diffraction study of ribulose-1,5-bisphosphate carboxylase from Rhodospirillum rubrum

scientific article published on 01 May 1984

Preliminary crystallographic data for stearoyl-acyl carrier protein desaturase from castor seed

scientific article

Preliminary crystallographic data for transketolase from yeast.

scientific article

Production, crystallization and preliminary crystallographic study of the major cat allergen Fel d 1.

scientific article published on 23 May 2003

Protein engineering of Rubisco

scientific article published on December 1991

Purification and preliminary X-ray crystallographic studies of recombinant 7,8-diaminopelargonic acid synthase from Escherichia coli

scientific article published on 01 November 1998

Purification and preliminary X-ray crystallographic studies of recombinant L-ribulose-5-phosphate 4-epimerase from Escherichia coli

scientific article

Purification, crystallization and preliminary crystallographic data for rat cytosolic selenocysteine 498 to cysteine mutant thioredoxin reductase

scientific article

Purification, crystallization and preliminary crystallographic study of an IDS-epimerase from Agrobacterium tumefaciens BY6.

scientific article published on 24 July 2006

Pyridoxal-phosphate dependent mycobacterial cysteine synthases: Structure, mechanism and potential as drug targets

scientific article

Rat acid phosphatase: overexpression of active, secreted enzyme by recombinant baculovirus-infected insect cells, molecular properties, and crystallization

scientific article

Rational protein design of ThDP-dependent enzymes-engineering stereoselectivity

scientific article

Redesign of soluble fatty acid desaturases from plants for altered substrate specificity and double bond position

scientific article published on May 1997

Redesigning the active site of transaldolase TalB from Escherichia coli: new variants with improved affinity towards nonphosphorylated substrates

scientific article

Refined structure of transketolase from Saccharomyces cerevisiae at 2.0 A resolution

scientific article

Replacement of a Phenylalanine by a Tyrosine in the Active Site Confers Fructose-6-phosphate Aldolase Activity to the Transaldolase of Escherichia coli and Human Origin

scientific article

RipD (Rv1566c) from Mycobacterium tuberculosis: adaptation of an NlpC/p60 domain to a non-catalytic peptidoglycan-binding function

scientific article

Siroheme- and [Fe4-S4]-dependent NirA from Mycobacterium tuberculosis is a sulfite reductase with a covalent Cys-Tyr bond in the active site

scientific journal article

Site-directed mutagenesis of prostatic acid phosphatase. Catalytically important aspartic acid 258, substrate specificity, and oligomerization

scientific journal article

Snapshot of a key intermediate in enzymatic thiamin catalysis: crystal structure of the alpha-carbanion of (alpha,beta-dihydroxyethyl)-thiamin diphosphate in the active site of transketolase from Saccharomyces cerevisiae

scientific article

Snapshot of a phosphorylated substrate intermediate by kinetic crystallography

scientific article

Structural Basis of the Differential Stability and Receptor Specificity of H-2Db in Complex with Murine versus Human β2-Microglobulin

article

Structural Insights into the UbiD Protein Family from the Crystal Structure of PA0254 from Pseudomonas aeruginosa

scientific article

Structural and evolutionary aspects of the key enzymes in photorespiration; RuBisCO and glycolate oxidase

scientific article published on 01 January 1987

Structural and functional characterization of ochratoxinase, a novel mycotoxin-degrading enzyme

scientific article

Structural basis for C-ribosylation in the alnumycin A biosynthetic pathway

scientific article

Structural basis for substrate recognition and specificity in aklavinone-11-hydroxylase from rhodomycin biosynthesis

scientific article

Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin

scientific article

Structural basis for the thioredoxin-like activity profile of the glutaredoxin-like NrdH-redoxin from Escherichia coli

scientific article

Structural enzymology of sulphur metabolism in Mycobacterium tuberculosis

scientific article published on May 2010

Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme alpha-aminoacrylate intermediate and an enzyme-inhibitor complex

scientific article

Structural insights into the regulatory mechanism of the response regulator RocR from Pseudomonas aeruginosa in cyclic Di-GMP signaling

scientific article

Structural proteomics: from the molecule to the system.

scientific article

Structural studies on corn nitrate reductase: refined structure of the cytochrome b reductase fragment at 2.5 A, its ADP complex and an active-site mutant and modeling of the cytochrome b domain

scientific article

Structure determination by multiwavelength anomalous diffraction of aclacinomycin oxidoreductase: indications of multidomain pseudomerohedral twinning

scientific article

Structure of HI-6*sarin-acetylcholinesterase determined by X-ray crystallography and molecular dynamics simulation: reactivator mechanism and design

scientific article published in 2009

Structure of LdtMt2, anL,D-transpeptidase fromMycobacterium tuberculosis

scientific article

Structure of PA4019, a putative aromatic acid decarboxylase fromPseudomonas aeruginosa

scientific article

Structure of dethiobiotin synthetase at 0.97 A resolution

scientific article

Structure of dethiobiotin synthetase at 0.97 Å resolution

Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed

scientific article

Structure of the branched-chain keto acid decarboxylase (KdcA) from Lactococcus lactis provides insights into the structural basis for the chemoselective and enantioselective carboligation reaction

scientific article

Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase

scientific article

Structure of the complex of active site metal-depleted horse liver alcohol dehydrogenase and NADH.

scientific article

Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation

scientific article

Structure-guided design of novel thiazolidine inhibitors of O-acetyl serine sulfhydrylase from Mycobacterium tuberculosis

scientific article

Substitution of ASP193 to ASN at the active site of ribulose-1,5-bisphosphate carboxylase results in conformational changes

scientific article

Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates

scientific article

Ta6Br14 is a useful cluster compound for isomorphous replacement in protein crystallography

scientific article published in March 1994

Tetrahydrodipicolinate N-Succinyltransferase and Dihydrodipicolinate Synthase from Pseudomonas aeruginosa: Structure Analysis and Gene Deletion

scientific article

The AEROPATH project targetingPseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery

scientific article

The C-terminal of CysM from Mycobacterium tuberculosis protects the aminoacrylate intermediate and is involved in sulfur donor selectivity

scientific article

The crystal structure of H-2Dd MHC class I complexed with the HIV-1-derived peptide P18-I10 at 2.4 A resolution: implications for T cell and NK cell recognition

scientific article

The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis

scientific article

The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family

scientific article

The dual-specific active site of 7,8-diaminopelargonic acid synthase and the effect of the R391A mutation

scientific article

The polyketide cyclase RemF from Streptomyces resistomycificus contains an unusual octahedral zinc binding site

scientific article

The structural basis of substrate activation in yeast pyruvate decarboxylase. A crystallographic and kinetic study

scientific article

The three-dimensional structure of human transaldolase

scientific article

Three-Dimensional Structure of Fel d 1, the Major Allergen in Cat

scientific article published on 01 September 2003

Three-dimensional Structure of Iminodisuccinate Epimerase Defines the Fold of the MmgE/PrpD Protein Family

Three-dimensional structure of a mammalian purple acid phosphatase at 2.2 A resolution with a mu-(hydr)oxo bridged di-iron center

scientific article

Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme

scientific article

Three-dimensional structure of apotransketolase flexible loops at the active site enable cofactor binding

scientific article published on 01 November 1992

Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 A resolution

scientific article

Three-dimensional structure of rat acid phosphatase

scientific article

Three-dimensional structure of rat acid phosphatase in complex with L(+)-tartrate

scientific article

Three-dimensional structure of transketolase, a thiamine diphosphate dependent enzyme, at 2.5 A resolution.

scientific article published on July 1992

Three-dimensional structures of apo- and holo-L-alanine dehydrogenase from Mycobacterium tuberculosis reveal conformational changes upon coenzyme binding

scientific article

Transaldolase B: trapping of Schiff base intermediate between dihydroxyacetone and epsilon-amino group of active-site lysine residue by borohydride reduction

scientific article published in January 2002

Truncation of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) from Rhodospirillum rubrum affects the holoenzyme assembly and activity.

scientific article

WAFL, a new protein involved in regulation of early endocytic transport at the intersection of actin and microtubule dynamics

scientific article

Yeast TKL1 gene encodes a transketolase that is required for efficient glycolysis and biosynthesis of aromatic amino acids.

scientific article

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